5/21/2025
Last update
5/21/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.3
USERS' SCORE
Good
Based on 27 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Boron (from 30 mg Bororganic Glycine)(Albion™)
3 mg
**
Top Medical Research Studies
8
We investigated the effectiveness of a novel compound, AN3485, on inflammation linked to arthritis. By administering AN3485 to mice, we discovered that it significantly reduced key inflammatory markers involved in arthritis over a 20-day period.
Our results showed that the compound successfully inhibited several pro-inflammatory cytokines, thus demonstrating its potential as a treatment for arthritis.
Overall, AN3485 may offer a promising pathway for managing arthritis and other inflammatory conditions.
Our results showed that the compound successfully inhibited several pro-inflammatory cytokines, thus demonstrating its potential as a treatment for arthritis.
Overall, AN3485 may offer a promising pathway for managing arthritis and other inflammatory conditions.
Read More
8
Boron shows potential for arthritis
We explored the effects of boron on arthritis, noting that evidence since 1963 indicates it may be a safe and effective treatment. Various studies suggest that people with arthritis often have lower boron levels, and boron supplementation could enhance bone strength. Notably, a controlled trial showed that 50% of osteoarthritis patients improved with 6 mg of boron daily, compared to just 10% on a placebo. Overall, while promising, more research is needed to fully understand boron's role in arthritis treatment and prevention.
Read More
9.5
Boron treatment aids arthritis inflammation
We investigated the potential of boron-10 liposomes combined with neutron irradiation to target macrophages in the knee joints of mice. Our study showed that injecting a boron-10 liposome solution resulted in high concentrations of boron within the macrophages.
Following neutron irradiation after the injection, we observed a significant reduction in macrophages nestled in the synovial lining. Importantly, this depletion led to decreased swelling and inflammation when arthritis was induced in the treated joints.
Histological analyses further confirmed the reduced inflammatory cell influx and protection against cartilage destruction.
Following neutron irradiation after the injection, we observed a significant reduction in macrophages nestled in the synovial lining. Importantly, this depletion led to decreased swelling and inflammation when arthritis was induced in the treated joints.
Histological analyses further confirmed the reduced inflammatory cell influx and protection against cartilage destruction.
Read More
Most Useful Reviews
9
Practically pain-free
146 people found this helpful
Life Changer. My arthritis feels nearly cured. I know this sounds unbelievable, but it is absolutely true! After suffering for 10 years with severe neck and back pain, I’ve finally found relief. I no longer require medication for my neck and back pain. It’s been nearly a month pain-free. I was diagnosed with arthritis in my neck, and while I'm not sure why this works, I won’t go without it in my life now.
Read More
6
Significant difference felt
84 people found this helpful
My daughter recommended this for arthritis, and I am pleased to report it works. When I stopped taking it after the first bottle, I immediately felt the difference and ordered more. Although it didn’t completely eliminate all my pain, it made a noticeable difference.
Read More
9
Improved mobility noted
82 people found this helpful
Not an easy convert, I read about boron and hoped to try it for my knees. The good news is that I no longer use my cane, and the chronic ache in my right knee has gone. I am grateful for this and recommend it to my wife, who has arthritis. The proof is in the lack of pain I now enjoy.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.3
- All Researches
9.5
Boron treatment aids arthritis inflammation
We investigated the potential of boron-10 liposomes combined with neutron irradiation to target macrophages in the knee joints of mice. Our study showed that injecting a boron-10 liposome solution resulted in high concentrations of boron within the macrophages.
Following neutron irradiation after the injection, we observed a significant reduction in macrophages nestled in the synovial lining. Importantly, this depletion led to decreased swelling and inflammation when arthritis was induced in the treated joints.
Histological analyses further confirmed the reduced inflammatory cell influx and protection against cartilage destruction.
Following neutron irradiation after the injection, we observed a significant reduction in macrophages nestled in the synovial lining. Importantly, this depletion led to decreased swelling and inflammation when arthritis was induced in the treated joints.
Histological analyses further confirmed the reduced inflammatory cell influx and protection against cartilage destruction.
Read More
9
This study explored a cutting-edge strategy using nanoparticles wrapped in macrophage membranes to treat rheumatoid arthritis.
The nanoparticles, designed to release 2-APB specifically in inflamed joints, successfully repolarized inflammatory macrophages, leading to reduced inflammation and joint damage in mouse models.
Overall, this innovative approach appears safe and effective, holding potential for better, targeted therapies for rheumatoid arthritis.
The nanoparticles, designed to release 2-APB specifically in inflamed joints, successfully repolarized inflammatory macrophages, leading to reduced inflammation and joint damage in mouse models.
Overall, this innovative approach appears safe and effective, holding potential for better, targeted therapies for rheumatoid arthritis.
Read More
9
We explored how 6-(benzoylamino)benzoxaborole analogs could impact inflammation related to arthritis. In laboratory tests, a compound called 1q effectively inhibited inflammation-causing cytokines.
When tested in mice, this compound reduced TNF-α and IL-6 levels and even showed improvement in collagen-induced arthritis.
These findings suggest that compound 1q could be a strong candidate for developing new anti-inflammatory treatments.
When tested in mice, this compound reduced TNF-α and IL-6 levels and even showed improvement in collagen-induced arthritis.
These findings suggest that compound 1q could be a strong candidate for developing new anti-inflammatory treatments.
Read More
8
We explored a new injectable hydrogel made from calcium boride nanosheets designed to deliver hydrogen gas for easing osteoarthritis (OA). This hydrogel helps maintain a stable environment that allows for more extended hydrogen release, lasting over a week. In our experiments, it showed the ability to scavenge harmful reactive oxygen species and reduce inflammation, which can ultimately protect joint health. Notably, a single injection significantly lessened joint damage in rats with OA. This innovative approach provides a promising option for alleviating OA symptoms and improving patient quality of life.
Read More
8
Boron treatment shows therapeutic promise
We explored the potential of boron neutron capture synovectomy (BNCS) as a treatment for rheumatoid arthritis using a model involving rabbits. This innovative approach applies boron compounds directly to the affected tissue followed by neutron irradiation.
Our study found that rabbits undergoing BNCS showed significant reductions in inflammatory markers without any toxic effects or pain. MRI results indicated healthy joint conditions post-treatment, resembling those of rabbits without arthritis. These findings suggest that low-dose BNCS could be an effective local therapy for rheumatoid arthritis.
Our study found that rabbits undergoing BNCS showed significant reductions in inflammatory markers without any toxic effects or pain. MRI results indicated healthy joint conditions post-treatment, resembling those of rabbits without arthritis. These findings suggest that low-dose BNCS could be an effective local therapy for rheumatoid arthritis.
Read More
User Reviews
USERS' SCORE
Good
Based on 27 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Practically pain-free
146 people found this helpful
Life Changer. My arthritis feels nearly cured. I know this sounds unbelievable, but it is absolutely true! After suffering for 10 years with severe neck and back pain, I’ve finally found relief. I no longer require medication for my neck and back pain. It’s been nearly a month pain-free. I was diagnosed with arthritis in my neck, and while I'm not sure why this works, I won’t go without it in my life now.
Read More
6
Significant difference felt
84 people found this helpful
My daughter recommended this for arthritis, and I am pleased to report it works. When I stopped taking it after the first bottle, I immediately felt the difference and ordered more. Although it didn’t completely eliminate all my pain, it made a noticeable difference.
Read More
9
Improved mobility noted
82 people found this helpful
Not an easy convert, I read about boron and hoped to try it for my knees. The good news is that I no longer use my cane, and the chronic ache in my right knee has gone. I am grateful for this and recommend it to my wife, who has arthritis. The proof is in the lack of pain I now enjoy.
Read More
9
Much better arthritis
28 people found this helpful
REALLY HELPS MY ARTHRITIS. I started taking boron about 5-6 years ago due to severe pain in my hands from arthritis. For months, I couldn’t use my fingers at all; my thumb joint was bright red and swollen. Following a friend's advice, I took a 3mg dose of boron, and the next day I noticed slight pain improvement. I take boron almost daily now, and my arthritis is significantly better. If I miss several days, my pain returns, so I recommend consulting with your healthcare provider before starting any supplements.
Read More
9
Effective for arthritis
28 people found this helpful
GREAT product... LOVE IT! An Australian doctor states that the absence of boron increases the prevalence of arthritis—I believe it! This has helped my arthritis more than anything else I’ve tried. I recommend it or a similar product for anyone suffering from arthritis.
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Frequently Asked Questions
7.5
Helps hands and wrists
7 people found this helpful
I take Now Boron along with MSM for arthritis, and it has helped. After a year of use, I’ve noticed an improvement in my hands and wrists.
7.5
Helpful for rheumatoid
3 people found this helpful
I have been using Boron Capsules for several years and found them to be very beneficial for my rheumatoid arthritis.
7.5
Decreases symptoms
This is a good form of boron at a reasonable price. Using boron has helped reduce some of my arthritis symptoms.
8
Minimises arthritis effects
3 people found this helpful
I take Boron to reduce the effects of arthritis, primarily in my hands. It appears to be effective where nothing else has helped. The delivery was timely as I was running low on capsules. It’s a good quality product, and Boron, being a mineral, is essential.
7.5
Helpful for density
I use this product for arthritis and bone density and found it to be beneficial for both. We observed an improvement in my daughter's bone density when she took this product regularly.
6
Minimal help
Boron is beneficial for arthritis; I bought it for my parents. It helps a bit, but perhaps not enough to provide a complete cure.
7.5
Good for relief
1 people found this helpful
I was advised to take Boron last year, and while it’s also present in multivitamins, I’m pleased with the relief it provides for my arthritis. These small capsules are very easy to swallow, and I have received excellent service from "iherbs."
8
Boron treatment shows therapeutic promise
We explored the potential of boron neutron capture synovectomy (BNCS) as a treatment for rheumatoid arthritis using a model involving rabbits. This innovative approach applies boron compounds directly to the affected tissue followed by neutron irradiation.
Our study found that rabbits undergoing BNCS showed significant reductions in inflammatory markers without any toxic effects or pain. MRI results indicated healthy joint conditions post-treatment, resembling those of rabbits without arthritis. These findings suggest that low-dose BNCS could be an effective local therapy for rheumatoid arthritis.
Our study found that rabbits undergoing BNCS showed significant reductions in inflammatory markers without any toxic effects or pain. MRI results indicated healthy joint conditions post-treatment, resembling those of rabbits without arthritis. These findings suggest that low-dose BNCS could be an effective local therapy for rheumatoid arthritis.
8
Boron shows potential for arthritis
We explored the effects of boron on arthritis, noting that evidence since 1963 indicates it may be a safe and effective treatment. Various studies suggest that people with arthritis often have lower boron levels, and boron supplementation could enhance bone strength. Notably, a controlled trial showed that 50% of osteoarthritis patients improved with 6 mg of boron daily, compared to just 10% on a placebo. Overall, while promising, more research is needed to fully understand boron's role in arthritis treatment and prevention.
References
- Zhou R, Xue S, Cheng Y, Chen Y, Wang Y, et al. Macrophage membrane-camouflaged biomimetic nanoparticles for rheumatoid arthritis treatment via modulating macrophage polarization. J Nanobiotechnology. 2024;22:578. 10.1186/s12951-024-02822-9
- Zhang W, Zeng L, Yu H, He Z, Huang C, et al. Injectable spontaneous hydrogen-releasing hydrogel for long-lasting alleviation of osteoarthritis. Acta Biomater. 2023;158:163. 10.1016/j.actbio.2022.12.056
- Trivillin VA, Bruno LJ, Gatti DA, Stur M, Garabalino MA, et al. Boron neutron capture synovectomy (BNCS) as a potential therapy for rheumatoid arthritis: radiobiological studies at RA-1 Nuclear Reactor in a model of antigen-induced arthritis in rabbits. Radiat Environ Biophys. 2016;55:467.
- Akama T, Dong C, Virtucio C, Freund YR, Chen D, et al. Discovery and structure-activity relationships of 6-(benzoylamino)benzoxaboroles as orally active anti-inflammatory agents. Bioorg Med Chem Lett. 2013;23:5870. 10.1016/j.bmcl.2013.08.096
- Dong C, Sexton H, Gertrudes A, Akama T, Martin S, et al. Inhibition of Toll-like receptor-mediated inflammation in vitro and in vivo by a novel benzoxaborole. J Pharmacol Exp Ther. 2013;344:436. 10.1124/jpet.112.200030
- van Lent PL, Krijger GC, Hofkens W, Nievaart VA, Sloetjes AW, et al. Selectively induced death of macrophages in the synovial lining of murine knee joints using 10B-liposomes and boron neutron capture synovectomy. Int J Radiat Biol. 2009;85:860. 10.1080/09553000903072454
- Watson-Clark RA, Banquerigo ML, Shelly K, Hawthorne MF, Brahn E. Model studies directed toward the application of boron neutron capture therapy to rheumatoid arthritis: boron delivery by liposomes in rat collagen-induced arthritis. Proc Natl Acad Sci U S A. 1998;95:2531.
- Newnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect. 1994;102 Suppl 7:83.
