Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Fish Oil Concentrate
1.3 g (1,300 mg)
†
Docosahexaenoic Acid (DHA)
1 g (1,000 mg)
†
Top Medical Research Studies
9
We explored the effectiveness of omega-3 fatty acid (PUFA) supplements in improving heart failure. Through a comprehensive network meta-analysis, we examined data from 14 randomized controlled trials involving over 9,000 participants.
Our findings showed that taking high doses of omega-3s (2000-4000 mg daily) for a year or more led to significant improvements in heart function, specifically in left ventricular ejection fraction and peak oxygen consumption. However, lower doses or shorter use didn’t yield these benefits, and there were no notable increases in dropout rates or overall mortality.
This suggests that while omega-3s can be beneficial for heart function in heart failure patients, careful consideration of the dosage and duration is essential.
Our findings showed that taking high doses of omega-3s (2000-4000 mg daily) for a year or more led to significant improvements in heart function, specifically in left ventricular ejection fraction and peak oxygen consumption. However, lower doses or shorter use didn’t yield these benefits, and there were no notable increases in dropout rates or overall mortality.
This suggests that while omega-3s can be beneficial for heart function in heart failure patients, careful consideration of the dosage and duration is essential.
9
We explored the potential of docosahexaenoic acid (DHA) in protecting against ischemic stroke in diabetic mice. The study found that administering DHA led to reduced stroke damage, including smaller brain infarcts and less brain swelling.
Interestingly, DHA appeared to lower inflammation by decreasing neutrophils in the brain and lessening apoptosis, which is cell death. Additionally, there were notable changes in gene expression, promoting anti-inflammatory and neuroprotective pathways.
Overall, DHA shows promise as a therapeutic option for managing strokes in diabetic patients.
Interestingly, DHA appeared to lower inflammation by decreasing neutrophils in the brain and lessening apoptosis, which is cell death. Additionally, there were notable changes in gene expression, promoting anti-inflammatory and neuroprotective pathways.
Overall, DHA shows promise as a therapeutic option for managing strokes in diabetic patients.
9
We explored how omega-3 polyunsaturated fatty acids (PUFAs) relate to coronary heart disease (CHD) risk through a thorough review of 36 studies. By looking at different types of omega-3 PUFAs, we found that higher levels correlate with a reduced risk of CHD. Specifically, both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) showed beneficial effects. In fact, CHD patients had noticeably lower omega-3 levels compared to healthy individuals, emphasizing the potential importance of these fatty acids in heart health.
Most Useful Reviews
7.5
Enhanced well-being
3 people found this helpful
DHA, or docosahexaenoic acid, has been a total game-changer for me. Since incorporating it into my daily routine, I have noticed a remarkable improvement in my overall well-being. It has enhanced my cognitive function and mental clarity, boosted my mood, and provided sustained energy throughout the day. The anti-inflammatory properties of DHA also alleviate joint discomfort and support my cardiovascular health. Knowing that I’m nourishing my body with this essential omega-3 fatty acid gives me peace of mind, and I highly recommend DHA to anyone aiming to optimise their health and unlock their full potential.
7.5
Effective DHA product
Good quality DHA! Each omega-3 product contains the primary ingredients DHA/EPA, and this one has a good balance and benefits. This is my third purchase as omega-3s significantly improve my cholesterol levels, cardiovascular health, and even intestinal inflammation.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.5
- All Researches
9
We examined how different fatty acid types, specifically acylcarnitines, affect heart health. Our study compared saturated and monounsaturated acylcarnitines with omega-3 derived types, like EPA and DHA. We found that saturated and monounsaturated types can harm heart function, significantly reducing cardiac contractility and cell viability. In contrast, the omega-3 acylcarnitines EPAC and DHAC did not impair heart functionality or cell viability. This suggests that omega-3s may offer a safer option for heart health compared to other fatty acids, particularly in those with specific health conditions.
9
We explored the effectiveness of omega-3 fatty acid (PUFA) supplements in improving heart failure. Through a comprehensive network meta-analysis, we examined data from 14 randomized controlled trials involving over 9,000 participants.
Our findings showed that taking high doses of omega-3s (2000-4000 mg daily) for a year or more led to significant improvements in heart function, specifically in left ventricular ejection fraction and peak oxygen consumption. However, lower doses or shorter use didn’t yield these benefits, and there were no notable increases in dropout rates or overall mortality.
This suggests that while omega-3s can be beneficial for heart function in heart failure patients, careful consideration of the dosage and duration is essential.
Our findings showed that taking high doses of omega-3s (2000-4000 mg daily) for a year or more led to significant improvements in heart function, specifically in left ventricular ejection fraction and peak oxygen consumption. However, lower doses or shorter use didn’t yield these benefits, and there were no notable increases in dropout rates or overall mortality.
This suggests that while omega-3s can be beneficial for heart function in heart failure patients, careful consideration of the dosage and duration is essential.
9
We explored the potential of docosahexaenoic acid (DHA) in protecting against ischemic stroke in diabetic mice. The study found that administering DHA led to reduced stroke damage, including smaller brain infarcts and less brain swelling.
Interestingly, DHA appeared to lower inflammation by decreasing neutrophils in the brain and lessening apoptosis, which is cell death. Additionally, there were notable changes in gene expression, promoting anti-inflammatory and neuroprotective pathways.
Overall, DHA shows promise as a therapeutic option for managing strokes in diabetic patients.
Interestingly, DHA appeared to lower inflammation by decreasing neutrophils in the brain and lessening apoptosis, which is cell death. Additionally, there were notable changes in gene expression, promoting anti-inflammatory and neuroprotective pathways.
Overall, DHA shows promise as a therapeutic option for managing strokes in diabetic patients.
9
We explored how omega-3 polyunsaturated fatty acids (PUFAs) relate to coronary heart disease (CHD) risk through a thorough review of 36 studies. By looking at different types of omega-3 PUFAs, we found that higher levels correlate with a reduced risk of CHD. Specifically, both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) showed beneficial effects. In fact, CHD patients had noticeably lower omega-3 levels compared to healthy individuals, emphasizing the potential importance of these fatty acids in heart health.
9
We explored how dihydroartemisinin (DHA) can protect the heart from damage caused by doxorubicin, a common cancer treatment. Through a series of tests on mice and heart cells, we found that DHA not only helped reduce heart dysfunction but also lessened oxidative stress and oxidative cell death.
The study demonstrated that DHA works by activating important cellular pathways and promoting the cleaning out of damaged cell parts. This means DHA could be a valuable option for mitigating the harmful effects of doxorubicin on the heart.
The study demonstrated that DHA works by activating important cellular pathways and promoting the cleaning out of damaged cell parts. This means DHA could be a valuable option for mitigating the harmful effects of doxorubicin on the heart.
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Enhanced well-being
3 people found this helpful
DHA, or docosahexaenoic acid, has been a total game-changer for me. Since incorporating it into my daily routine, I have noticed a remarkable improvement in my overall well-being. It has enhanced my cognitive function and mental clarity, boosted my mood, and provided sustained energy throughout the day. The anti-inflammatory properties of DHA also alleviate joint discomfort and support my cardiovascular health. Knowing that I’m nourishing my body with this essential omega-3 fatty acid gives me peace of mind, and I highly recommend DHA to anyone aiming to optimise their health and unlock their full potential.
7.5
Effective DHA product
Good quality DHA! Each omega-3 product contains the primary ingredients DHA/EPA, and this one has a good balance and benefits. This is my third purchase as omega-3s significantly improve my cholesterol levels, cardiovascular health, and even intestinal inflammation.
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Liepinsh E, Gukalova B, Krims-Davis K, Kuka J, Leduskrasta A, et al. EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines. Biofactors. 2025;51:e70014. doi:10.1002/biof.70014
- Medoro A, Graziano F, Cardinale G, Voccola S, Zotti T, et al. The influence of FADS1 and ELOVL2 genetic polymorphisms on polyunsaturated fatty acid composition in response to fish oil supplementation. Lipids Health Dis. 2025;24:102. doi:10.1186/s12944-025-02513-w
- Tseng PT, Zeng BY, Hsu CW, Liang CS, Stubbs B, et al. The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis. Adv Nutr. 2025;16:100366. doi:10.1016/j.advnut.2025.100366
- Li J, Guo J, Yuen M, Yuen H, Peng Q. The comparative effects of ω-7 fatty acid-rich sea buckthorn oil and ω-3 fatty acid-rich DHA algal oil on improving high-fat diet-induced hyperlipidemia. Food Funct. 2025;16:1241. doi:10.1039/d4fo04961f
- Liu C, Guo J, Guan L, Li C, Hu X, et al. Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis. Exp Neurol. 2025;385:115075. doi:10.1016/j.expneurol.2024.115075
- Hegde PS, Agni MB, Rai P, Upadhyay SS, Aravind A, et al. Supplementation of diet with Astaxanthin and DHA prevents gestational and lactational undernourishment-induced metabolic derangements in dams: a metabolomic approach. J Dev Orig Health Dis. 2024;15:e30. doi:10.1017/S2040174424000345
- Lee YQ, Tan KH, Chong MF. Biomarkers of PUFA and cardiovascular risk factors and events in healthy Asian populations: a systematic review. Br J Nutr. 2024;132:1474. doi:10.1017/S0007114524002708
- Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, et al. Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis. Eur J Prev Cardiol. 2025;32:233. doi:10.1093/eurjpc/zwae315
- Zhang P, Munier JJ, Wiese CB, Vergnes L, Link JC, et al. X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction. Nat Commun. 2024;15:5571. doi:10.1038/s41467-024-49764-2
- Xiao Y, Chen Y, Pietzner A, Elbelt U, Fan Z, et al. Circulating Omega-3 Polyunsaturated Fatty Acids Levels in Coronary Heart Disease: Pooled Analysis of 36 Observational Studies. Nutrients. 2024;16. doi:10.3390/nu16111610
- Dinu M, Sofi F, Lotti S, Colombini B, Mattioli AV, et al. Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis. Eur J Prev Cardiol. 2024;31:1863. doi:10.1093/eurjpc/zwae184
- Lin ZH, Xiang HQ, Yu YW, Xue YJ, Wu C, et al. Dihydroartemisinin alleviates doxorubicin-induced cardiotoxicity and ferroptosis by activating Nrf2 and regulating autophagy. FASEB J. 2024;38:e23677. doi:10.1096/fj.202400222RR
- Hamaya R, Cook NR, Sesso HD, Buring JE, Manson JE. A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events. Am J Clin Nutr. 2025. doi:10.1016/j.ajcnut.2025.02.028
- Liboriussen C, Nygaard L, Jensen JD, Schmidt EB, Glerup RI, et al. Low Plasma Marine N-3 Polyunsaturated Fatty Acids are Associated with Increased Risk of Cardiovascular Events in Patients Treated with Maintenance Hemodialysis. J Ren Nutr. 2025. doi:10.1053/j.jrn.2025.02.001
- Yunoki K, Matsumi H, Miyoshi T, Kubo M, Hata Y, et al. Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy. J Cardiovasc Dev Dis. 2025;12. doi:10.3390/jcdd12020060
- Ren Y, Chen B, Zhang H, Xu S. A cohort study reveals shared and distinct serum metabolic biomarkers for major adverse cardiovascular events in middle-aged and older adults. Geroscience. 2025. doi:10.1007/s11357-025-01544-6
- Kim JY, Kong SYJ, Jung E, Cho YS. Omega-3 Fatty Acids as Potential Predictors of Sudden Cardiac Death and Cardiovascular Mortality: A Systematic Review and Meta-Analysis. J Clin Med. 2024;14. doi:10.3390/jcm14010026
- Arghavani H, Bilodeau JF, Rudkowska I. Association Between Circulating Fatty Acids and Blood Pressure: A Review. Curr Nutr Rep. 2025;14:15. doi:10.1007/s13668-024-00602-3
- Lamon-Fava S. Associations between omega-3 fatty acid-derived lipid mediators and markers of inflammation in older subjects with low-grade chronic inflammation. Prostaglandins Other Lipid Mediat. 2025;176:106948. doi:10.1016/j.prostaglandins.2025.106948
- Berkowitz L, Echeverría G, Salazar C, Faúndez C, Coe CL, et al. Lipidomic Signature of Healthy Diet Adherence and Its Association with Cardiometabolic Risk in American Adults. Nutrients. 2024;16. doi:10.3390/nu16233995
- O'Keefe EL, O'Keefe JH, Abuissa H, Metzinger M, Murray E, et al. Omega-3 and Risk of atrial fibrillation: Vagally-mediated double-edged sword. Prog Cardiovasc Dis. 2024. doi:10.1016/j.pcad.2024.11.003
- So J, Yao JH, Magadmi R, Matthan NR, Lamon-Fava S. Sex differences in lipid mediators derived from omega-3 fatty acids in older individuals with low-grade chronic inflammation. Prostaglandins Leukot Essent Fatty Acids. 2024;203:102655. doi:10.1016/j.plefa.2024.102655
- Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. doi:10.3389/fnut.2024.1423228
- Koutsaliaris IK, Pantazi D, Tsouka AN, Argyropoulou O, Tellis CC, et al. Differential Effect of Omega-3 Fatty Acids on Platelet Inhibition by Antiplatelet Drugs In Vitro. Int J Mol Sci. 2024;25. doi:10.3390/ijms251810136
