Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.6
USERS' SCORE
Good
Based on 5 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Bromelain (2400 GDU/g)† (from Pineapple)
500 mg
*

Top Medical Research Studies

We examined how bromelain, a pineapple extract, helps in identifying allergies to Hymenoptera venom. By analyzing serum from 51 patients, we found that many presented cross-reactive IgE due to a carbohydrate called CCD.

Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.

Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Read More
8
Bromelain reduces allergic airway inflammation
We explored how bromelain, a natural extract from pineapples, influences allergic airway disease in a mouse model. Mice were sensitized and treated with bromelain or saline over several days.

Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.

However, further research is needed to confirm these effects in human subjects.
Read More
The study looked into how plant-made influenza vaccines interact with the immune system, particularly concerning allergies. We followed 280 participants over six months, monitoring for allergic reactions and measuring specific antibodies.

While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
Read More

Most Useful Reviews

10
Life-changing relief
33 people found this helpful
I have terrible allergies and have dealt with nasal polyps all my life. Having undergone two surgeries and tried various treatments, I was sceptical about this product. However, I decided to give it a go—best decision I ever made! I felt a difference after the first pill. A week later, I could breathe and smell again! It has changed my life. I take one pill each morning and have had no problems with polyps or breathing. I highly recommend this product.
Read More
10
Joint pain relief
8 people found this helpful
It really works with Quercetin! This product cured my joint pain and seasonal allergies. I take it together with Quercetin, and I am extremely grateful for the results.
Read More
9
Aids mucus reduction
157 people found this helpful
I read online that bromelain helps reduce mucus, which I usually struggle with. These have significantly helped, especially as I often deal with allergies and persistent post-nasal drip. They are effective, but ensure to choose one with at least 2,000 gdu for optimal results.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.6
  • All Researches
The study looked into how plant-made influenza vaccines interact with the immune system, particularly concerning allergies. We followed 280 participants over six months, monitoring for allergic reactions and measuring specific antibodies.

While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
Read More
We examined how bromelain, a pineapple extract, helps in identifying allergies to Hymenoptera venom. By analyzing serum from 51 patients, we found that many presented cross-reactive IgE due to a carbohydrate called CCD.

Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.

Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Read More
8
Bromelain reduces allergic airway inflammation
We explored how bromelain, a natural extract from pineapples, influences allergic airway disease in a mouse model. Mice were sensitized and treated with bromelain or saline over several days.

Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.

However, further research is needed to confirm these effects in human subjects.
Read More
8
Bromelain aids sinusitis recovery
We examined how bromelain, an enzyme derived from pineapple, affects children under 11 with acute sinusitis. In our study involving 116 patients across Germany, we compared those treated with bromelain alone, standard treatments, and a mix of both.

The results revealed that the bromelain group had the quickest recovery, with symptoms lasting about 6.66 days. Interestingly, only one patient had a mild allergic reaction, which was self-limiting. Overall, bromelain appears to provide a beneficial treatment option for young children suffering from acute sinusitis.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Life-changing relief
33 people found this helpful
I have terrible allergies and have dealt with nasal polyps all my life. Having undergone two surgeries and tried various treatments, I was sceptical about this product. However, I decided to give it a go—best decision I ever made! I felt a difference after the first pill. A week later, I could breathe and smell again! It has changed my life. I take one pill each morning and have had no problems with polyps or breathing. I highly recommend this product.
Read More
10
Joint pain relief
8 people found this helpful
It really works with Quercetin! This product cured my joint pain and seasonal allergies. I take it together with Quercetin, and I am extremely grateful for the results.
Read More
9
Aids mucus reduction
157 people found this helpful
I read online that bromelain helps reduce mucus, which I usually struggle with. These have significantly helped, especially as I often deal with allergies and persistent post-nasal drip. They are effective, but ensure to choose one with at least 2,000 gdu for optimal results.
Read More
7.5
Thins sinus issues
22 people found this helpful
So far, so great! The items arrived promptly and in excellent condition. I took one last night alongside Quercetin and one this morning. I've begun this for my sinus issues and physical pain, seeking asthma relief. Although it is early to review, I already feel some improvement. My sinuses seem less swollen, I’m breathing easier, and my body feels relaxed, with less pain. There is also some urgent bathroom need, not painful, but as long as it remains manageable, I’m okay. I’m thrilled to see how this progresses as I continue taking it!
Read More
7.5
Reduces seasonal allergies
20 people found this helpful
Helped tremendously with allergies. Initially, I bought these capsules to reduce swelling following a tummy tuck surgery but noticed seasonal allergies were less severe too. I didn't attribute the improvement to these until I read other reviews highlighting their benefits for mucus and congestion. I can confirm these capsules definitely assisted with my allergies.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Abram DM, Fernandes LGR, Perez-Riverol A, Regina Brochetto-Braga M, Zollner RL. Cross-Reactive Carbohydrate Determinant in , and Venoms: Identification of Allergic Sensitization and Cross-Reactivity. Toxins (Basel). 2020;12. 10.3390/toxins12100649
  2. Ward BJ, Landry N, Trépanier S, Mercier G, Dargis M, et al. Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines. Vaccine. 2014;32:6098. 10.1016/j.vaccine.2014.08.079
  3. Secor ER, Carson WF, Cloutier MM, Guernsey LA, Schramm CM, et al. Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease. Cell Immunol. 2005;237:68.
  4. Braun JM, Schneider B, Beuth HJ. Therapeutic use, efficiency and safety of the proteolytic pineapple enzyme Bromelain-POS in children with acute sinusitis in Germany. In Vivo. 2005;19:417.
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