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Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.2
USERS' SCORE
Good
Based on 14 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Bromelain (2400 GDU/g)†(from Pineapple)
500 mg
*
Top Medical Research Studies
8
We explored a new way to deliver bromelain, a natural enzyme, using nanostructured lipid carriers (Br-NCs).
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Read More
8
We evaluated the effects of a new glucosamine combination, which includes bromelain, on cartilage damage in rats induced by formalin. The study involved different groups of rats, including a control group, and assessed various biochemical and gene expression markers after 30 days of treatment.
Our findings showed that the new combination significantly reduced markers of inflammation and oxidative damage while improving antioxidants compared to the control group. Notably, this new formula helped protect cartilage, indicating its potential clinical relevance for osteoarthritis treatment. However, the standard glucosamine combination did not demonstrate similar benefits.
Our findings showed that the new combination significantly reduced markers of inflammation and oxidative damage while improving antioxidants compared to the control group. Notably, this new formula helped protect cartilage, indicating its potential clinical relevance for osteoarthritis treatment. However, the standard glucosamine combination did not demonstrate similar benefits.
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4
We aimed to understand how bromelain, an enzyme from pineapples, affects knee osteoarthritis (OA) over a 16-week period. Our randomized, single-blind pilot study involved 40 participants who received either bromelain or diclofenac.
While both groups showed improvements in pain and function after four weeks, no significant differences emerged between the treatments. By week 16, bromelain users showed some enhancements in WOMAC scores and reductions in oxidative stress markers. However, bromelain didn't significantly outperform diclofenac in relieving OA symptoms.
While both groups showed improvements in pain and function after four weeks, no significant differences emerged between the treatments. By week 16, bromelain users showed some enhancements in WOMAC scores and reductions in oxidative stress markers. However, bromelain didn't significantly outperform diclofenac in relieving OA symptoms.
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Most Useful Reviews
9
Substantial improvement
75 people found this helpful
This works for arthritis. My mum suffered for 15 years before trying Bromelain caps. After following the correct regimen, her swelling and pain greatly reduced. It takes time and consistency, but we’re seeing improvement.
Read More
7.5
Manageable pain
32 people found this helpful
Amazing relief for my arthritis! After two months, my osteoarthritis pain is far more manageable. I have diminished the need for Aleve and can enjoy life more. I highly recommend trying Bromelain!
Read More
9
Notable difference
31 people found this helpful
For my osteoarthritis, this really works! After trying many methods, I've noticed a significant drop in pain while taking Bromelain. Transitioning from sitting to standing is much easier now. Highly recommend for arthritis sufferers who can't take aspirin.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.2
- All Researches
8
We explored a new way to deliver bromelain, a natural enzyme, using nanostructured lipid carriers (Br-NCs).
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Read More
8
This pilot study focused on whether a food supplement containing bromelain and Boswellia could enhance the quality of life for osteoarthritis (OA) patients. Over 49 participants took the supplement for 1 to 6 months and reported on their daily activities.
We found that, after treatment, 7 out of 10 questions regarding patient quality of life showed significant improvements, especially in the joints most affected. Notably, no adverse effects were reported.
These findings suggest that this combination may serve as a helpful, non-drug option for OA patients, paving the way for further research.
We found that, after treatment, 7 out of 10 questions regarding patient quality of life showed significant improvements, especially in the joints most affected. Notably, no adverse effects were reported.
These findings suggest that this combination may serve as a helpful, non-drug option for OA patients, paving the way for further research.
Read More
8
We evaluated the effects of a new glucosamine combination, which includes bromelain, on cartilage damage in rats induced by formalin. The study involved different groups of rats, including a control group, and assessed various biochemical and gene expression markers after 30 days of treatment.
Our findings showed that the new combination significantly reduced markers of inflammation and oxidative damage while improving antioxidants compared to the control group. Notably, this new formula helped protect cartilage, indicating its potential clinical relevance for osteoarthritis treatment. However, the standard glucosamine combination did not demonstrate similar benefits.
Our findings showed that the new combination significantly reduced markers of inflammation and oxidative damage while improving antioxidants compared to the control group. Notably, this new formula helped protect cartilage, indicating its potential clinical relevance for osteoarthritis treatment. However, the standard glucosamine combination did not demonstrate similar benefits.
Read More
8
We evaluated how a blend of three natural ingredients—Devil's claw, turmeric, and bromelain—could help alleviate osteoarthritis pain. Conducted in eight rheumatology centers, the study looked at both acute and chronic pain experienced by 42 participants, mostly women around 67 years old.
After taking AINAT capsules, patients reported a significant reduction in joint pain within three days for acute cases and 60 days for chronic cases. With an excellent safety profile, this natural remedy offers a promising alternative to conventional painkillers for those suffering from joint discomfort.
After taking AINAT capsules, patients reported a significant reduction in joint pain within three days for acute cases and 60 days for chronic cases. With an excellent safety profile, this natural remedy offers a promising alternative to conventional painkillers for those suffering from joint discomfort.
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8
We explored how bromelain affects mild acute knee pain in healthy individuals. This study involved volunteers taking either 200 mg or 400 mg of bromelain per day for a month.
The results were promising: both dosage groups reported significant reductions in pain and overall improvement in well-being. The high-dose group experienced even greater benefits, suggesting that more bromelain leads to better outcomes.
However, further double-blind, placebo-controlled studies are necessary to confirm these findings and fully understand bromelain's role in joint health.
The results were promising: both dosage groups reported significant reductions in pain and overall improvement in well-being. The high-dose group experienced even greater benefits, suggesting that more bromelain leads to better outcomes.
However, further double-blind, placebo-controlled studies are necessary to confirm these findings and fully understand bromelain's role in joint health.
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User Reviews
USERS' SCORE
Good
Based on 14 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Substantial improvement
75 people found this helpful
This works for arthritis. My mum suffered for 15 years before trying Bromelain caps. After following the correct regimen, her swelling and pain greatly reduced. It takes time and consistency, but we’re seeing improvement.
Read More
7.5
Manageable pain
32 people found this helpful
Amazing relief for my arthritis! After two months, my osteoarthritis pain is far more manageable. I have diminished the need for Aleve and can enjoy life more. I highly recommend trying Bromelain!
Read More
9
Notable difference
31 people found this helpful
For my osteoarthritis, this really works! After trying many methods, I've noticed a significant drop in pain while taking Bromelain. Transitioning from sitting to standing is much easier now. Highly recommend for arthritis sufferers who can't take aspirin.
Read More
9
Significant pain relief
20 people found this helpful
Bought these for floaters but they ended up helping my arthritis in hands. I initially wanted to get rid of the numerous floaters in my eyes, which did not improve. However, they significantly reduced the arthritis pain in my hands. Each morning, I take one on an empty stomach and the pain has almost gone—about 90% reduced. If I skip doses, the pain returns. I'm nearly finished with this bottle and have ordered more. I'm very pleased, although I wish it helped with the floaters too.
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9
Significant help
14 people found this helpful
I have seen significant help with arthritis pain since taking Bromelain. I read studies that used it for osteoarthritis and noticed a major difference in joint pain; it’s been very effective for me.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Brochard S, Pontin J, Bernay B, Boumediene K, Conrozier T, et al. The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells. BMC Complement Med Ther. 2021;21:261. 10.1186/s12906-021-03435-7
- Sharma M, Chaudhary D. Exploration of bromelain laden nanostructured lipid carriers: An oral platform for bromelain delivery in rheumatoid arthritis management. Int J Pharm. 2021;594:120176. 10.1016/j.ijpharm.2020.120176
- Italiano G, Raimondo M, Giannetti G, Gargiulo A. Benefits of a Food Supplement Containing and Bromelain for Improving the Quality of Life in Patients with Osteoarthritis: A Pilot Study. J Altern Complement Med. 2020;26:123. 10.1089/acm.2019.0258
- Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016;35:2531. 10.1007/s10067-016-3363-1
- Ucuncu Y, Celik N, Ozturk C, Turkoglu M, Cetin N, et al. Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation. Life Sci. 2015;130:31. 10.1016/j.lfs.2015.03.012
- Conrozier T, Mathieu P, Bonjean M, Marc JF, Renevier JL, et al. A complex of three natural anti-inflammatory agents provides relief of osteoarthritis pain. Altern Ther Health Med. 2014;20 Suppl 1:32.
- Akhtar NM, Naseer R, Farooqi AZ, Aziz W, Nazir M. Oral enzyme combination versus diclofenac in the treatment of osteoarthritis of the knee--a double-blind prospective randomized study. Clin Rheumatol. 2004;23:410.
- Walker AF, Bundy R, Hicks SM, Middleton RW. Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults. Phytomedicine. 2002;9:681.
- Desser L, Holomanova D, Zavadova E, Pavelka K, Mohr T, et al. Oral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human blood. Cancer Chemother Pharmacol. 2001;47 Suppl:S10.
