' 
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.3
USERS' SCORE
Medium or Average
Based on 121 Reviews
6.2
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
Top Medical Research Studies
7
CMT shows potential for pain relief
The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study.
Moderate relevance for clinical practice
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
Pamidronate therapy reduces bone pain
New trends in the treatment of osteogenesis imperfecta type III - own experience.
Study demonstrates effective treatment
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
Calcium's effect isn't isolated
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
Most Useful Reviews
9.5
Strengthened nails
NowFoods provides excellent quality calcium and magnesium. This supplement noticeably improved my nails, making them stronger and shinier. I also experienced less tooth sensitivity thanks to magnesium's calming effects. Overall, I highly recommend this supplement for strengthening nails, teeth, and providing nervous system stability.
Read More
9.5
Improved teeth sensitivity
Magnesium has significantly reduced my teeth sensitivity and improved my bone health. My nails grew stronger, and my skin looked fresher during the one-month course I completed regularly. I was pleased with the results, which lasted for months.
Read More
9.5
Pain relief achieved
This calcium is remarkable! Previously, I had issues with my knee and hip joints for five years after surgery. After consuming half a jar of this calcium, I experienced significant relief. I had been limping but can now walk and even run. The pain that used to occur weekly has vanished. I'm thrilled to have forgotten about my arthritis!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.3
- All Researches
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
Calcium's effect isn't isolated
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
7
Promising drug delivery for osteoporosis
Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis.
High relevance due to innovative approach
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
Pamidronate therapy reduces bone pain
New trends in the treatment of osteogenesis imperfecta type III - own experience.
Study demonstrates effective treatment
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
CMT shows potential for pain relief
The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study.
Moderate relevance for clinical practice
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 121 Reviews
6.2
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Strengthened nails
NowFoods provides excellent quality calcium and magnesium. This supplement noticeably improved my nails, making them stronger and shinier. I also experienced less tooth sensitivity thanks to magnesium's calming effects. Overall, I highly recommend this supplement for strengthening nails, teeth, and providing nervous system stability.
Read More
9.5
Improved teeth sensitivity
Magnesium has significantly reduced my teeth sensitivity and improved my bone health. My nails grew stronger, and my skin looked fresher during the one-month course I completed regularly. I was pleased with the results, which lasted for months.
9.5
Pain relief achieved
This calcium is remarkable! Previously, I had issues with my knee and hip joints for five years after surgery. After consuming half a jar of this calcium, I experienced significant relief. I had been limping but can now walk and even run. The pain that used to occur weekly has vanished. I'm thrilled to have forgotten about my arthritis!
Read More
9.5
Eliminated leg pain
I started taking this during pregnancy after waking up at night with leg pain. Since then, I haven’t experienced any pain, and my muscles aren’t cramping. The capsules are large but easy to swallow. I noticed a positive effect on my teeth as well.
10
Stopped leg cramps
This product is miraculous! I had sharp pains in my legs and cramps, but after starting it, everything disappeared within five days. Even my 70-year-old neighbour experienced similar relief after taking it.
