Magnesium may protect against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study.
Direct magnesium impact on gout
We examined the relationship between magnesium levels and the occurrence of bone erosion in patients with gouty arthritis. In our analysis, we observed that 769 gout patients were studied, allowing us to classify them into groups based on their serum ionized magnesium levels.
The results were striking: those with lower magnesium levels had a significantly higher rate of bone erosion. Specifically, patients in the lowest magnesium group showed a bone erosion prevalence rate of over 60%, compared to less than 45% in those with higher magnesium levels.
Our findings suggest that maintaining adequate levels of magnesium might offer a protective effect against bone deterioration in gout arthritis. This points to the possibility that magnesium supplementation could be beneficial for preventing or slowing down bone erosion in these patients.
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We investigated the relationship between magnesium deficiency and the risk of developing gout by analyzing data from 18,039 adults in the National Health and Nutrition Examination Survey from 2007 to 2016. The magnesium depletion score (MDS) was used to assess magnesium status, revealing a significant positive correlation between higher MDS levels and gout risks.
Specifically, we found that individuals with an MDS score of 2 or higher had noticeably greater odds of experiencing gout compared to those with no magnesium deficiency. However, interestingly, our analysis indicated that dietary magnesium intake did not influence this correlation, suggesting that simply increasing magnesium in one's diet may not effectively lower gout risk.
Overall, while our findings highlight a clear link between magnesium deficiency and gout, they also emphasize that magnesium treatment on its own might not provide the relief or preventative effects one might hope for in managing gout. It seems dietary choices related to magnesium are not enough to alter gout risks, calling for further exploration into other treatments or lifestyle factors.
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