'
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.2
USERS' SCORE
Moderately Good
Based on 27 Reviews
7.7
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%

Top Medical Research Studies

9
Magnesium aids migraine management
Magnesium and Migraine.
Directly studies magnesium’s effect
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
9.5
Calcium's uncertain headache impact
Reversible Cerebral Vasoconstriction Syndrome Secondary to Escitalopram.
Study raises questions on effectiveness
We explored the connection between calcium treatment and headaches, particularly in patients with reversible cerebral vasoconstriction syndrome (RCVS). In this case, we observed a healthy young woman who had been using escitalopram for a long time. She presented with bilateral neurological deficits, and after treatment with intra-arterial calcium channel blockers, her symptoms improved significantly.

However, it’s important to note that while calcium channel blockers were administered, the study does not specifically isolate calcium’s effects on headache relief. This combination of treatments makes it challenging to understand how much calcium alone contributes to alleviating headache symptoms, if at all.

As we considered the overall findings, it became clear that while calcium channel blockers can lead to symptom improvement in RCVS, the direct impact of calcium on headaches remains uncertain. Therefore, individuals experiencing thunderclap headaches, especially those on selective serotonin reuptake inhibitors, should consider RCVS as a possible diagnosis, but we cannot definitively conclude that calcium treatment is effective for headaches based on this case alone.
Read More
7
Magnesium's efficacy for headaches
Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur.
Moderate relevance for magnesium use
We explored the impact of magnesium treatment on headaches, focusing specifically on its role in preventing migraines. The evidence suggests that magnesium may be beneficial for some individuals in managing headache frequency and intensity. It is often recommended not only for migraine prevention but also for acute treatment when given intravenously.

Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.

Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
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Most Useful Reviews

8.8
Reduced headaches
The doctor identified my lack of calcium and magnesium. After two weeks of taking these supplements, I noticed that the pain in my joints due to the weather and my headaches had lessened significantly. It’s important to use them purposefully, as overdosing can lead to poor reviews. One capsule a day lasts a long time with the sizeable container!
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9.5
Headache relief
I highly recommend this magnesium supplement! It helps relax my muscles and alleviates leg cramps. I've introduced it to my sister and friend, and they’ve also seen benefits. Magnesium serves as a natural anti-stress agent and can help with anxiety, insomnia, and headaches—conditions I often had due to magnesium deficiency.
Read More
8.3
Muscle relaxation
I highly recommend this! After taking it for a long time, it’s the only thing that helps relax my chewing muscles and leg cramps. I've also advised friends to try it, as magnesium helps reduce anxiety and stressed states that lead to headaches.
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Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.2
9.5
Calcium's uncertain headache impact
Reversible Cerebral Vasoconstriction Syndrome Secondary to Escitalopram.
Study raises questions on effectiveness
We explored the connection between calcium treatment and headaches, particularly in patients with reversible cerebral vasoconstriction syndrome (RCVS). In this case, we observed a healthy young woman who had been using escitalopram for a long time. She presented with bilateral neurological deficits, and after treatment with intra-arterial calcium channel blockers, her symptoms improved significantly.

However, it’s important to note that while calcium channel blockers were administered, the study does not specifically isolate calcium’s effects on headache relief. This combination of treatments makes it challenging to understand how much calcium alone contributes to alleviating headache symptoms, if at all.

As we considered the overall findings, it became clear that while calcium channel blockers can lead to symptom improvement in RCVS, the direct impact of calcium on headaches remains uncertain. Therefore, individuals experiencing thunderclap headaches, especially those on selective serotonin reuptake inhibitors, should consider RCVS as a possible diagnosis, but we cannot definitively conclude that calcium treatment is effective for headaches based on this case alone.
Read More
9
Magnesium aids migraine management
Magnesium and Migraine.
Directly studies magnesium’s effect
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
9
Magnesium's role in headache treatment
[Therapeutic approaches to comorbid pathology in episodic migraine and tension-type headache].
Combined treatment limits magnesium's isolation
We examined the effects of magnesium treatment on individuals suffering from episodic migraine and tension-type headache, aiming to understand its potential benefits alongside other therapeutic approaches. The study involved 104 participants, who were assessed for anxiety, depression, insomnia, and fatigue before and after receiving various treatments, including magnesium.

Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.

Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
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8
Magnesium shows potential in VM therapy
Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study.
Combination product limits specific conclusions.
We conducted a study assessing how nonprescription therapies, particularly a combination product containing magnesium, affect symptoms of vestibular migraine (VM). Our research involved collecting data from patients diagnosed with VM who were given guidance on lifestyle changes, like hydration and nutrition, alongside the supplement.

After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.

Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.

Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
Read More
8
Migraine connection in Meniere's disease
Meniere's disease is a manifestation of migraine.
Magnesium's role in migraine treatment
We examined the idea that Meniere's disease (MD) might actually be a form of migraine rather than just a standalone inner ear issue. Interestingly, we found that while only about 12% of the general population deals with migraines, a staggering 51-60% of those with MD also experience migraine headaches regularly.

Furthermore, we learned that endolymphatic hydrops, a key feature often associated with MD, has also been spotted in people suffering from vestibular migraine. This connection hints that treating migraine might also benefit those with MD. A particularly effective approach we've seen involves changes in diet and lifestyle, along with magnesium and riboflavin supplements, and possibly preventative medication to manage migraine symptoms.

By treating the underlying migraine aspect, we observed that patients with MD can find relief and improvement. This indicates that MD might best be approached as a migraine-related condition, opening up new avenues for effective treatment strategies.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 27 Reviews
7.7
9.5
Headache relief
I highly recommend this magnesium supplement! It helps relax my muscles and alleviates leg cramps. I've introduced it to my sister and friend, and they’ve also seen benefits. Magnesium serves as a natural anti-stress agent and can help with anxiety, insomnia, and headaches—conditions I often had due to magnesium deficiency.
Read More
9.5
Headache relief
This calcium and magnesium supplement truly works. I’ve found relief from sleep disturbances, headaches, and irritability since taking it consistently for years. It’s my go-to for these issues.
9.5
Reduced headaches
I took this for better nail growth and improved sleep, and it worked wonders. My insomnia and headaches have decreased significantly, and I now feel calmer overall, making it ideal for anyone with such issues.
9.5
Headache improvement
After suffering from chronic headaches, I suspected magnesium deficiency. Once I began this supplement, the headaches disappeared, which I attribute to finally addressing my dietary deficiencies.
9.5
Headache prevention
Since being diagnosed with positional vertigo, I’ve been taking calcium to supplement my soy milk diet, which has benefitted my migraines. I'm grateful for this supplement as it combines both calcium and magnesium.
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