Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.6
USERS' SCORE
Moderately Good
Based on 27 Reviews
7.1
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
Top Medical Research Studies
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
8
We examined how various tocolytic drugs delay preterm birth, analyzing data from 122 trials involving nearly 13,700 women.
Our findings suggest that all classes of tocolytics, including magnesium sulfate, are likely effective for delaying birth up to 7 days compared to no treatment.
While these treatments showed promise, they also carried risks of side effects, such as nausea and headaches, particularly with betamimetics and calcium channel blockers. We found no definitive conclusions on their impact on neonatal outcomes, leaving room for further research.
Our findings suggest that all classes of tocolytics, including magnesium sulfate, are likely effective for delaying birth up to 7 days compared to no treatment.
While these treatments showed promise, they also carried risks of side effects, such as nausea and headaches, particularly with betamimetics and calcium channel blockers. We found no definitive conclusions on their impact on neonatal outcomes, leaving room for further research.
Read More
9.5
We explored the connection between calcium treatment and headaches, particularly in patients with reversible cerebral vasoconstriction syndrome (RCVS). In this case, we observed a healthy young woman who had been using escitalopram for a long time. She presented with bilateral neurological deficits, and after treatment with intra-arterial calcium channel blockers, her symptoms improved significantly.
However, it’s important to note that while calcium channel blockers were administered, the study does not specifically isolate calcium’s effects on headache relief. This combination of treatments makes it challenging to understand how much calcium alone contributes to alleviating headache symptoms, if at all.
As we considered the overall findings, it became clear that while calcium channel blockers can lead to symptom improvement in RCVS, the direct impact of calcium on headaches remains uncertain. Therefore, individuals experiencing thunderclap headaches, especially those on selective serotonin reuptake inhibitors, should consider RCVS as a possible diagnosis, but we cannot definitively conclude that calcium treatment is effective for headaches based on this case alone.
However, it’s important to note that while calcium channel blockers were administered, the study does not specifically isolate calcium’s effects on headache relief. This combination of treatments makes it challenging to understand how much calcium alone contributes to alleviating headache symptoms, if at all.
As we considered the overall findings, it became clear that while calcium channel blockers can lead to symptom improvement in RCVS, the direct impact of calcium on headaches remains uncertain. Therefore, individuals experiencing thunderclap headaches, especially those on selective serotonin reuptake inhibitors, should consider RCVS as a possible diagnosis, but we cannot definitively conclude that calcium treatment is effective for headaches based on this case alone.
Read More
Most Useful Reviews
7.5
Reduced headaches
11 people found this helpful
The doctor identified my lack of calcium and magnesium. After two weeks of taking these supplements, I noticed that the pain in my joints due to the weather and my headaches had lessened significantly. It’s important to use them purposefully, as overdosing can lead to poor reviews. One capsule a day lasts a long time with the sizeable container!
Read More
9
Headache relief
5 people found this helpful
I highly recommend this magnesium supplement! It helps relax my muscles and alleviates leg cramps. I've introduced it to my sister and friend, and they’ve also seen benefits. Magnesium serves as a natural anti-stress agent and can help with anxiety, insomnia, and headaches—conditions I often had due to magnesium deficiency.
Read More
9
Muscle relaxation
4 people found this helpful
I highly recommend this! After taking it for a long time, it’s the only thing that helps relax my chewing muscles and leg cramps. I've also advised friends to try it, as magnesium helps reduce anxiety and stressed states that lead to headaches.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.6
- All Researches
9.5
We explored the connection between calcium treatment and headaches, particularly in patients with reversible cerebral vasoconstriction syndrome (RCVS). In this case, we observed a healthy young woman who had been using escitalopram for a long time. She presented with bilateral neurological deficits, and after treatment with intra-arterial calcium channel blockers, her symptoms improved significantly.
However, it’s important to note that while calcium channel blockers were administered, the study does not specifically isolate calcium’s effects on headache relief. This combination of treatments makes it challenging to understand how much calcium alone contributes to alleviating headache symptoms, if at all.
As we considered the overall findings, it became clear that while calcium channel blockers can lead to symptom improvement in RCVS, the direct impact of calcium on headaches remains uncertain. Therefore, individuals experiencing thunderclap headaches, especially those on selective serotonin reuptake inhibitors, should consider RCVS as a possible diagnosis, but we cannot definitively conclude that calcium treatment is effective for headaches based on this case alone.
However, it’s important to note that while calcium channel blockers were administered, the study does not specifically isolate calcium’s effects on headache relief. This combination of treatments makes it challenging to understand how much calcium alone contributes to alleviating headache symptoms, if at all.
As we considered the overall findings, it became clear that while calcium channel blockers can lead to symptom improvement in RCVS, the direct impact of calcium on headaches remains uncertain. Therefore, individuals experiencing thunderclap headaches, especially those on selective serotonin reuptake inhibitors, should consider RCVS as a possible diagnosis, but we cannot definitively conclude that calcium treatment is effective for headaches based on this case alone.
Read More
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
9
We examined the effects of magnesium treatment on individuals suffering from episodic migraine and tension-type headache, aiming to understand its potential benefits alongside other therapeutic approaches. The study involved 104 participants, who were assessed for anxiety, depression, insomnia, and fatigue before and after receiving various treatments, including magnesium.
Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.
Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.
Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
Read More
9
We explored a case involving a 36-year-old woman with endometriosis suffering from frequent headaches and debilitating pain. While traditional medications didn't work for her, she started a new treatment plan that included acupuncture and supplements like magnesium and turmeric.
After this multimodal approach, her headache frequency decreased significantly, along with improvements in her lumbopelvic pain, sleep quality, and overall focus. This case indicates that integrating various alternative therapies can provide significant relief for those with challenging symptoms.
After this multimodal approach, her headache frequency decreased significantly, along with improvements in her lumbopelvic pain, sleep quality, and overall focus. This case indicates that integrating various alternative therapies can provide significant relief for those with challenging symptoms.
Read More
8
We conducted a study assessing how nonprescription therapies, particularly a combination product containing magnesium, affect symptoms of vestibular migraine (VM). Our research involved collecting data from patients diagnosed with VM who were given guidance on lifestyle changes, like hydration and nutrition, alongside the supplement.
After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.
Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.
Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.
Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.
Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 27 Reviews
7.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced headaches
11 people found this helpful
The doctor identified my lack of calcium and magnesium. After two weeks of taking these supplements, I noticed that the pain in my joints due to the weather and my headaches had lessened significantly. It’s important to use them purposefully, as overdosing can lead to poor reviews. One capsule a day lasts a long time with the sizeable container!
Read More
9
Headache relief
5 people found this helpful
I highly recommend this magnesium supplement! It helps relax my muscles and alleviates leg cramps. I've introduced it to my sister and friend, and they’ve also seen benefits. Magnesium serves as a natural anti-stress agent and can help with anxiety, insomnia, and headaches—conditions I often had due to magnesium deficiency.
Read More
9
Muscle relaxation
4 people found this helpful
I highly recommend this! After taking it for a long time, it’s the only thing that helps relax my chewing muscles and leg cramps. I've also advised friends to try it, as magnesium helps reduce anxiety and stressed states that lead to headaches.
Read More
9
Headache prevention
1 people found this helpful
Since being diagnosed with positional vertigo, I’ve been taking calcium to supplement my soy milk diet, which has benefitted my migraines. I'm grateful for this supplement as it combines both calcium and magnesium.
Read More
9
Migraine improvement
1 people found this helpful
This is a great supplement. After years of suffering from migraine headaches with little effect from prescribed medications, I was advised to take Magnesium alongside other supplements. My migraines have improved significantly, and I love this product—it works for me.
Read More
Frequently Asked Questions
7.5
Reduced headaches
11 people found this helpful
The doctor identified my lack of calcium and magnesium. After two weeks of taking these supplements, I noticed that the pain in my joints due to the weather and my headaches had lessened significantly. It’s important to use them purposefully, as overdosing can lead to poor reviews. One capsule a day lasts a long time with the sizeable container!
9
Headache relief
3 people found this helpful
This calcium and magnesium supplement truly works. I’ve found relief from sleep disturbances, headaches, and irritability since taking it consistently for years. It’s my go-to for these issues.
9
Headache improvement
1 people found this helpful
After suffering from chronic headaches, I suspected magnesium deficiency. Once I began this supplement, the headaches disappeared, which I attribute to finally addressing my dietary deficiencies.
9
Headache relief
5 people found this helpful
I highly recommend this magnesium supplement! It helps relax my muscles and alleviates leg cramps. I've introduced it to my sister and friend, and they’ve also seen benefits. Magnesium serves as a natural anti-stress agent and can help with anxiety, insomnia, and headaches—conditions I often had due to magnesium deficiency.
9
Reduced headaches
1 people found this helpful
I took this for better nail growth and improved sleep, and it worked wonders. My insomnia and headaches have decreased significantly, and I now feel calmer overall, making it ideal for anyone with such issues.
9
Headache prevention
1 people found this helpful
Since being diagnosed with positional vertigo, I’ve been taking calcium to supplement my soy milk diet, which has benefitted my migraines. I'm grateful for this supplement as it combines both calcium and magnesium.
0
Severe headache
1 people found this helpful
If I take this alone, my headache becomes so severe that I have to lie down without anything.
9
Pregnancy relief
My obstetrician recommended magnesium for my severe headaches during the first trimester. After taking it, my symptoms significantly reduced for the remainder of my pregnancy.
7.5
Less discomfort
6 people found this helpful
I realised the effects of taking magnesium as my joint pain from menopause and headaches before menstruation have drastically decreased. I started this regular supplement to improve the balance of magnesium and calcium.
0
Stop taking it
I've been taking magnesium alone, but I switched to this due to calcium deficiency during pregnancy. It caused me headaches and diarrhoea, which is unusual for me, so I will stop taking it.
2
More headaches felt
I had to switch to these instead of my usual magnesium and calcium. I’ve experienced more muscular pain, cramps, and headaches since. Even taking three per day did not help. It highlights the need for a proper balance of supplements.
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
7
We explored the impact of magnesium treatment on headaches, focusing specifically on its role in preventing migraines. The evidence suggests that magnesium may be beneficial for some individuals in managing headache frequency and intensity. It is often recommended not only for migraine prevention but also for acute treatment when given intravenously.
Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.
Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.
Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
8
We conducted a study assessing how nonprescription therapies, particularly a combination product containing magnesium, affect symptoms of vestibular migraine (VM). Our research involved collecting data from patients diagnosed with VM who were given guidance on lifestyle changes, like hydration and nutrition, alongside the supplement.
After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.
Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.
Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.
Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.
Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
7
The effectiveness of magnesium in treating headaches has garnered attention, particularly when we consider its potential role as a dietary supplement for both children and adults. In examining its impact, studies have indeed explored how magnesium may help alleviate headache symptoms.
Our review highlighted research findings that suggest magnesium may not only reduce headache frequency but also the intensity of pain experienced during episodes. Interestingly, some studies specifically noted that certain dietary supplements, including magnesium, could yield positive outcomes for individuals suffering from headaches.
It’s important to note, however, that while there are promising indications, the evaluation of magnesium's effectiveness often comes paired with other treatments. This raises questions about its isolated impact. Therefore, while there’s evidence pointing to magnesium's benefits, its exact role, particularly when not combined with other therapies, remains to be clarified.
Our review highlighted research findings that suggest magnesium may not only reduce headache frequency but also the intensity of pain experienced during episodes. Interestingly, some studies specifically noted that certain dietary supplements, including magnesium, could yield positive outcomes for individuals suffering from headaches.
It’s important to note, however, that while there are promising indications, the evaluation of magnesium's effectiveness often comes paired with other treatments. This raises questions about its isolated impact. Therefore, while there’s evidence pointing to magnesium's benefits, its exact role, particularly when not combined with other therapies, remains to be clarified.
References
- Postolowski M, Shakil O, Ramachandran L, Rao CV. Reversible Cerebral Vasoconstriction Syndrome Secondary to Escitalopram. Clin Med Res. 2024;22:222. doi:10.3121/cmr.2025.1864
- Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725
- Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. doi:10.1007/s11916-025-01358-3
- Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. doi:10.1111/imj.16314
- Mirzaeva LM, Lobzina AS, Akhmedova KN, Shvartsman GI, Kula II, et al. [Therapeutic approaches to comorbid pathology in episodic migraine and tension-type headache]. Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123:52. doi:10.17116/jnevro202312309152
- Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
- Frank M, Abouzari M, Djalilian HR. Meniere's disease is a manifestation of migraine. Curr Opin Otolaryngol Head Neck Surg. 2023;31:313. doi:10.1097/MOO.0000000000000908
- Verhaak A, Bakaysa S, Johnson A, Veronesi M, Williamson A, et al. Migraine treatment in pregnancy: A survey of comfort and treatment practices of women's healthcare providers. Headache. 2023;63:211. doi:10.1111/head.14436
- Mahajan R, Anand KS, Mahajan RK, Garg J, Juneja A. Serum Magnesium Levels During the Ictal and Interictal Phase in Patients of Migraine: A Prospective Observational Study. Neurol India. 2022;70:1852. doi:10.4103/0028-3886.359247
- Wilson A, Hodgetts-Morton VA, Marson EJ, Markland AD, Larkai E, et al. Tocolytics for delaying preterm birth: a network meta-analysis (0924). Cochrane Database Syst Rev. 2022;8:CD014978. doi:10.1002/14651858.CD014978.pub2
- Bhurat R, Premkumar S, Manokaran RK. Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study. Indian Pediatr. 2022;59:623.
- Bharadwaj VN, Meyerowitz J, Zou B, Klukinov M, Yan N, et al. Impact of Magnesium on Oxytocin Receptor Function. Pharmaceutics. 2022;14. doi:10.3390/pharmaceutics14051105
- Martin BR. Multimodal Care for Headaches, Lumbopelvic Pain, and Dysmenorrhea in a Woman With Endometriosis: A Case Report. J Chiropr Med. 2021;20:148. doi:10.1016/j.jcm.2021.10.002
