' 
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
Top Medical Research Studies
9
Magnesium chloride reduces liver stress
Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats.
Moderate relevance to health impacts.
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
Read More
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
Relevant for hypertension and cholesterol
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
Read More
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
Highly relevant findings for health
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
Read More
Most Useful Reviews
9.5
Convenient combination
Excellent! When taking calcium, it's not absorbed effectively unless magnesium is included, making this combination very convenient. I highly recommend it for women.
Read More
8.8
Lowered blood pressure
Useful for bone health and reducing blood pressure! My readings for high cholesterol improved slightly while taking this supplement alongside my medication. Additionally, my hair has grown quicker and stronger. The tablets may be large for some, though. For better absorption, I recommend taking vitamin D3 and K2 together; vegan options are available. Natural sources like sunlight and natto also provide vitamin D and K.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.1
- All Researches
9
Embelin influences cholesterol metabolism
Embelin Elevates Endoplasmic Reticulum Calcium Levels and Blocks the Sterol Regulatory Element-Binding Protein 2 Mediated Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Improves the Low-Density Lipoprotein Receptor Mediated Lipid Clearance on Hepatocytes.
Calcium's impact on cholesterol highlighted.
We examined the effects of embelin, a compound derived from the dried berries of Embelia ribes, on cholesterol levels by focusing on its relationship with calcium in liver cells. Our analysis showed that embelin treatment aids in regulating cholesterol metabolism by influencing key proteins associated with cholesterol clearance.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
Read More
9
Magnesium chloride reduces liver stress
Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats.
Moderate relevance to health impacts.
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
Read More
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
Relevant for hypertension and cholesterol
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
Read More
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
Highly relevant findings for health
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
Read More
8
Magnesium helps reduce cholesterol risk
An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations.
Strong correlation with cardiovascular factors
We examined how magnesium levels in urine relate to cardiovascular disease risk factors, focusing on cholesterol and other health measures. In a large, diverse group of 4,211 participants from 50 countries, we found that higher urinary magnesium was linked to lower body mass index, blood pressure, and total cholesterol.
Notably, people with the highest magnesium levels experienced significantly lower risks for obesity and hypertension compared to those with the lowest levels. These findings suggest that increasing magnesium intake may have meaningful benefits for heart health.
Notably, people with the highest magnesium levels experienced significantly lower risks for obesity and hypertension compared to those with the lowest levels. These findings suggest that increasing magnesium intake may have meaningful benefits for heart health.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Convenient combination
Excellent! When taking calcium, it's not absorbed effectively unless magnesium is included, making this combination very convenient. I highly recommend it for women.
8.8
Lowered blood pressure
Useful for bone health and reducing blood pressure! My readings for high cholesterol improved slightly while taking this supplement alongside my medication. Additionally, my hair has grown quicker and stronger. The tablets may be large for some, though. For better absorption, I recommend taking vitamin D3 and K2 together; vegan options are available. Natural sources like sunlight and natto also provide vitamin D and K.
Read More
