Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 4 g)
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
4 g
1%**
Dietary Fiber
4 g
14%*
Organic Inulin (FOS) (from Blue Agave)
3.3 g
†
Top Medical Research Studies
8
Bradykinin enhances tumor permeability
We investigated the effects of bradykinin on the permeability of tumor capillaries to various substances, including inulin, in a model of RG2 glioma in rats. In this study, bradykinin was administered through the carotid artery to see how it would alter the capillary barrier in brain tumors.
Our findings revealed that bradykinin significantly increased the permeability of tumor vessels to several tracers, including inulin. Specifically, the permeability for inulin was 23.92, compared to just 6.20 in the control group receiving saline. This indicates that bradykinin may play a role in enhancing the ability of substances like inulin to penetrate brain tumors, which could have implications for drug delivery in such conditions.
It's important to note that the permeability changes observed were limited to the tumor sites and did not affect normal brain tissue. Moreover, once the bradykinin infusion was stopped, the increased permeability returned to baseline levels within 20 minutes, emphasizing the temporary nature of its effect. Overall, our research highlights the potential for using bradykinin to improve the delivery of treatments for brain tumors by temporarily opening up the blood-tumor barrier.
Our findings revealed that bradykinin significantly increased the permeability of tumor vessels to several tracers, including inulin. Specifically, the permeability for inulin was 23.92, compared to just 6.20 in the control group receiving saline. This indicates that bradykinin may play a role in enhancing the ability of substances like inulin to penetrate brain tumors, which could have implications for drug delivery in such conditions.
It's important to note that the permeability changes observed were limited to the tumor sites and did not affect normal brain tissue. Moreover, once the bradykinin infusion was stopped, the increased permeability returned to baseline levels within 20 minutes, emphasizing the temporary nature of its effect. Overall, our research highlights the potential for using bradykinin to improve the delivery of treatments for brain tumors by temporarily opening up the blood-tumor barrier.
Read More
7
This study explored the effects of RMP-7, a bradykinin analog, on enhancing the delivery of treatments to brain tumors, specifically RG2 glial tumors in rats. By infusing RMP-7 directly into the carotid artery, we found that it significantly increased the permeability of the tumor's capillaries to various substances, including inulin.
While we did observe a rise in inulin uptake in tumors treated with RMP-7, it is important to note that the infusion did not significantly enhance the permeability of normal brain capillaries. This selective improvement suggests that RMP-7 could be a promising technique for delivering therapeutic agents directly to tumors without affecting healthy brain tissue.
However, our results indicate that the isolated benefits of inulin as an individual treatment weren't the primary focus, as the study centered more on RMP-7's ability to enhance overall drug delivery. Thus, while inulin's role is highlighted, it does not hold standalone significance within this study's findings.
While we did observe a rise in inulin uptake in tumors treated with RMP-7, it is important to note that the infusion did not significantly enhance the permeability of normal brain capillaries. This selective improvement suggests that RMP-7 could be a promising technique for delivering therapeutic agents directly to tumors without affecting healthy brain tissue.
However, our results indicate that the isolated benefits of inulin as an individual treatment weren't the primary focus, as the study centered more on RMP-7's ability to enhance overall drug delivery. Thus, while inulin's role is highlighted, it does not hold standalone significance within this study's findings.
Read More
Most Useful Reviews
7.5
Gut-brain connection
7 people found this helpful
Inulin works wonderfully! We’ve given up probiotics to focus solely on prebiotics, and it has profoundly impacted my life and my children’s. It’s crucial to nourish the existing good bacteria rather than continuously introducing new strains. I've seen improvements in my daughter's concentration and a decrease in her aggressiveness. A healthy gut promotes a healthy brain—this prebiotic is a fantastic choice!
Read More
9
Weight loss aid
6 people found this helpful
This is the best probiotic I've ever tried! As a prebiotic, it's essential for our microflora and beneficial for everyone. It's excellent for preventing dysbacteriosis and cleaning the stomach, making it particularly useful for those wishing to lose weight. When dissolved in water, inulin creates a gelatinous substance that aids in appetite control and reduces body weight. It also boosts immunity and helps cleanse the liver. Moreover, it decreases the risk of various tumors. Overall, contraindications are virtually absent.
Read More
9
Improved mental clarity
8 people found this helpful
Inulin is fantastic for brain health! I purchased it for the Nemechek programme for children with developmental delays, and my entire family uses it. It’s particularly essential not only for my child but also for me to understand the treatment process thoroughly. After a month, we've seen wonderful results—my child is noticeably calmer, and their intellect and engagement have improved significantly. We're committed to using it for about a year as part of the programme.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
Bradykinin enhances tumor permeability
We investigated the effects of bradykinin on the permeability of tumor capillaries to various substances, including inulin, in a model of RG2 glioma in rats. In this study, bradykinin was administered through the carotid artery to see how it would alter the capillary barrier in brain tumors.
Our findings revealed that bradykinin significantly increased the permeability of tumor vessels to several tracers, including inulin. Specifically, the permeability for inulin was 23.92, compared to just 6.20 in the control group receiving saline. This indicates that bradykinin may play a role in enhancing the ability of substances like inulin to penetrate brain tumors, which could have implications for drug delivery in such conditions.
It's important to note that the permeability changes observed were limited to the tumor sites and did not affect normal brain tissue. Moreover, once the bradykinin infusion was stopped, the increased permeability returned to baseline levels within 20 minutes, emphasizing the temporary nature of its effect. Overall, our research highlights the potential for using bradykinin to improve the delivery of treatments for brain tumors by temporarily opening up the blood-tumor barrier.
Our findings revealed that bradykinin significantly increased the permeability of tumor vessels to several tracers, including inulin. Specifically, the permeability for inulin was 23.92, compared to just 6.20 in the control group receiving saline. This indicates that bradykinin may play a role in enhancing the ability of substances like inulin to penetrate brain tumors, which could have implications for drug delivery in such conditions.
It's important to note that the permeability changes observed were limited to the tumor sites and did not affect normal brain tissue. Moreover, once the bradykinin infusion was stopped, the increased permeability returned to baseline levels within 20 minutes, emphasizing the temporary nature of its effect. Overall, our research highlights the potential for using bradykinin to improve the delivery of treatments for brain tumors by temporarily opening up the blood-tumor barrier.
Read More
7
This study explored the effects of RMP-7, a bradykinin analog, on enhancing the delivery of treatments to brain tumors, specifically RG2 glial tumors in rats. By infusing RMP-7 directly into the carotid artery, we found that it significantly increased the permeability of the tumor's capillaries to various substances, including inulin.
While we did observe a rise in inulin uptake in tumors treated with RMP-7, it is important to note that the infusion did not significantly enhance the permeability of normal brain capillaries. This selective improvement suggests that RMP-7 could be a promising technique for delivering therapeutic agents directly to tumors without affecting healthy brain tissue.
However, our results indicate that the isolated benefits of inulin as an individual treatment weren't the primary focus, as the study centered more on RMP-7's ability to enhance overall drug delivery. Thus, while inulin's role is highlighted, it does not hold standalone significance within this study's findings.
While we did observe a rise in inulin uptake in tumors treated with RMP-7, it is important to note that the infusion did not significantly enhance the permeability of normal brain capillaries. This selective improvement suggests that RMP-7 could be a promising technique for delivering therapeutic agents directly to tumors without affecting healthy brain tissue.
However, our results indicate that the isolated benefits of inulin as an individual treatment weren't the primary focus, as the study centered more on RMP-7's ability to enhance overall drug delivery. Thus, while inulin's role is highlighted, it does not hold standalone significance within this study's findings.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Gut-brain connection
7 people found this helpful
Inulin works wonderfully! We’ve given up probiotics to focus solely on prebiotics, and it has profoundly impacted my life and my children’s. It’s crucial to nourish the existing good bacteria rather than continuously introducing new strains. I've seen improvements in my daughter's concentration and a decrease in her aggressiveness. A healthy gut promotes a healthy brain—this prebiotic is a fantastic choice!
Read More
9
Weight loss aid
6 people found this helpful
This is the best probiotic I've ever tried! As a prebiotic, it's essential for our microflora and beneficial for everyone. It's excellent for preventing dysbacteriosis and cleaning the stomach, making it particularly useful for those wishing to lose weight. When dissolved in water, inulin creates a gelatinous substance that aids in appetite control and reduces body weight. It also boosts immunity and helps cleanse the liver. Moreover, it decreases the risk of various tumors. Overall, contraindications are virtually absent.
Read More
9
Improved mental clarity
8 people found this helpful
Inulin is fantastic for brain health! I purchased it for the Nemechek programme for children with developmental delays, and my entire family uses it. It’s particularly essential not only for my child but also for me to understand the treatment process thoroughly. After a month, we've seen wonderful results—my child is noticeably calmer, and their intellect and engagement have improved significantly. We're committed to using it for about a year as part of the programme.
Read More
7.5
Immunity boost
2 people found this helpful
Excellent! Inulin helps with weight loss by creating a feeling of satiety without added calories. It boosts immunity, cleans the liver, accelerates digestion, and removes heavy metals. It also reduces the risk of various tumors and aids in vitamin absorption. A truly beneficial product!
Read More
Frequently Asked Questions
9
Improved mental clarity
8 people found this helpful
Inulin is fantastic for brain health! I purchased it for the Nemechek programme for children with developmental delays, and my entire family uses it. It’s particularly essential not only for my child but also for me to understand the treatment process thoroughly. After a month, we've seen wonderful results—my child is noticeably calmer, and their intellect and engagement have improved significantly. We're committed to using it for about a year as part of the programme.
7.5
Gut-brain connection
7 people found this helpful
Inulin works wonderfully! We’ve given up probiotics to focus solely on prebiotics, and it has profoundly impacted my life and my children’s. It’s crucial to nourish the existing good bacteria rather than continuously introducing new strains. I've seen improvements in my daughter's concentration and a decrease in her aggressiveness. A healthy gut promotes a healthy brain—this prebiotic is a fantastic choice!
7.5
Immunity boost
2 people found this helpful
Excellent! Inulin helps with weight loss by creating a feeling of satiety without added calories. It boosts immunity, cleans the liver, accelerates digestion, and removes heavy metals. It also reduces the risk of various tumors and aids in vitamin absorption. A truly beneficial product!
8
Bradykinin enhances tumor permeability
We investigated the effects of bradykinin on the permeability of tumor capillaries to various substances, including inulin, in a model of RG2 glioma in rats. In this study, bradykinin was administered through the carotid artery to see how it would alter the capillary barrier in brain tumors.
Our findings revealed that bradykinin significantly increased the permeability of tumor vessels to several tracers, including inulin. Specifically, the permeability for inulin was 23.92, compared to just 6.20 in the control group receiving saline. This indicates that bradykinin may play a role in enhancing the ability of substances like inulin to penetrate brain tumors, which could have implications for drug delivery in such conditions.
It's important to note that the permeability changes observed were limited to the tumor sites and did not affect normal brain tissue. Moreover, once the bradykinin infusion was stopped, the increased permeability returned to baseline levels within 20 minutes, emphasizing the temporary nature of its effect. Overall, our research highlights the potential for using bradykinin to improve the delivery of treatments for brain tumors by temporarily opening up the blood-tumor barrier.
Our findings revealed that bradykinin significantly increased the permeability of tumor vessels to several tracers, including inulin. Specifically, the permeability for inulin was 23.92, compared to just 6.20 in the control group receiving saline. This indicates that bradykinin may play a role in enhancing the ability of substances like inulin to penetrate brain tumors, which could have implications for drug delivery in such conditions.
It's important to note that the permeability changes observed were limited to the tumor sites and did not affect normal brain tissue. Moreover, once the bradykinin infusion was stopped, the increased permeability returned to baseline levels within 20 minutes, emphasizing the temporary nature of its effect. Overall, our research highlights the potential for using bradykinin to improve the delivery of treatments for brain tumors by temporarily opening up the blood-tumor barrier.
7
This study explored the effects of RMP-7, a bradykinin analog, on enhancing the delivery of treatments to brain tumors, specifically RG2 glial tumors in rats. By infusing RMP-7 directly into the carotid artery, we found that it significantly increased the permeability of the tumor's capillaries to various substances, including inulin.
While we did observe a rise in inulin uptake in tumors treated with RMP-7, it is important to note that the infusion did not significantly enhance the permeability of normal brain capillaries. This selective improvement suggests that RMP-7 could be a promising technique for delivering therapeutic agents directly to tumors without affecting healthy brain tissue.
However, our results indicate that the isolated benefits of inulin as an individual treatment weren't the primary focus, as the study centered more on RMP-7's ability to enhance overall drug delivery. Thus, while inulin's role is highlighted, it does not hold standalone significance within this study's findings.
While we did observe a rise in inulin uptake in tumors treated with RMP-7, it is important to note that the infusion did not significantly enhance the permeability of normal brain capillaries. This selective improvement suggests that RMP-7 could be a promising technique for delivering therapeutic agents directly to tumors without affecting healthy brain tissue.
However, our results indicate that the isolated benefits of inulin as an individual treatment weren't the primary focus, as the study centered more on RMP-7's ability to enhance overall drug delivery. Thus, while inulin's role is highlighted, it does not hold standalone significance within this study's findings.
References
- Inamura T, Nomura T, Bartus RT, Black KL. Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors. J Neurosurg. 1994;81:752.
- Inamura T, Black KL. Bradykinin selectively opens blood-tumor barrier in experimental brain tumors. J Cereb Blood Flow Metab. 1994;14:862.
