Inulin aids ulcer preventionInulin-rich fractions from Vernonia kotschyana roots have anti-ulcer activity.
Directly supports traditional uses
We examined the potential effects of inulin-rich extracts from the roots of Vernonia kotschyana on gastritis, particularly its anti-ulcer properties. The roots are recognized in Mali for their traditional use in treating gastric issues like gastritis and ulcers, sold under the name Gastrosedal.
In our research, we analyzed two different water extracts from these roots, from 50°C and 100°C extractions, to see how they could impact stomach ulcers induced in mice. The study highlighted that both extracts contained high levels of inulin—98% in the cooler extract and 83% in the hotter one.
The results were promising, as both VK50-I and VK100-I displayed a significant ability to inhibit ulcer formation in the mice. Interestingly, despite these positive findings, we did not observe any significant immunomodulating activities or toxicity associated with the extracts.
This suggests that inulin may play a vital role in safeguarding the gastrointestinal tract's health, particularly in combating conditions such as gastritis. Overall, our findings support the traditional use of Vernonia kotschyana as a natural remedy for stomach-related ailments.
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