Can NOW Supplements Sambucus Zinc-C Elderberry Concentrate and Vitamin C Help with Sinusitis?

SCIENTIFIC SCORE

Questionable

Based on 3 Researches

6.7

USERS' SCORE

Good

Based on 2 Reviews

8.6

Supplement Facts

Serving Size: 1 Lozenge

Amount Per Serving

%DV

Calories

Total Carbohydrate

<1 g

<1%**

Total Sugars

0 g

†

Includes 0 g Added Sugars

0%**

Xylitol

<1 g

†

Vitamin C (as Ascorbic Acid)

100 mg

111%

Zinc (elemental) (from 15 mg Zinc Bisglycinate) (TRAACS™)

3 mg

27%

Elderberry (10:1 Concentrate)(Sambucus nigra) (Fruit)

150 mg

†

Top Medical Research Studies

Vitamin C aids chloride transport

Effect of L-ascorbate on chloride transport in freshly excised sinonasal epithelia.

Relevant to sinusitis treatment

We explored the effects of L-ascorbate, commonly known as Vitamin C, on chloride transport in sinonasal epithelial tissues. This research is particularly significant as it addresses the common condition of chronic rhinosinusitis (CRS) and its potential link to the function of the cystic fibrosis transmembrane conductance regulator (CFTR) — a key chloride ion channel.

During our investigation, we utilized freshly excised sinonasal tissues from both normal individuals and patients suffering from CRS. The tissues were carefully prepared and tested to understand how L-ascorbate influenced chloride secretion. Our findings revealed that the application of L-ascorbate notably enhanced chloride secretion in these tissues.

This is important because optimal chloride transport is essential for maintaining healthy mucosal surfaces and effective mucociliary clearance. Therefore, since decreased chloride secretion could lead to the worsening of sinus conditions, L-ascorbate presents a promising avenue for therapeutic intervention in improving mucociliary clearance for those affected by chronic sinus issues.

Vitamin C aids sinusitis recovery

[Clinical and biochemical aspects in the treatment of acute maxillary sinusitis with antioxidants].

Examines mixed antioxidant approach

We evaluated the impact of antioxidants, specifically vitamin C, on acute maxillary sinusitis treatment through a study involving different treatment approaches. Patients received a mix of dibunol and vitamin C, delivered into the sinuses, while others only had traditional treatments like ampicillin and hydrocortisone.

This study involved control groups that helped us compare the effectiveness of the antioxidant treatment. Stunningly, we found that those receiving the antioxidant mixture demonstrated substantial improvements, with shorter treatment times and fewer overall interventions compared to the control group.

Additionally, positive changes in certain blood markers indicated that the antioxidant approach markedly enhanced the body's response to infection. These findings underscore the potential benefits of including vitamin C as part of a sinusitis treatment plan, especially when dealing with acute flare-ups.

Zinc Levels and Sinusitis Effects

Comparison of serum zinc levels between patients with sinonasal neutrophilic and eosinophilic inflammatory polyposis and healthy individuals.

Limited treatment insights on zinc

We explored the connection between zinc levels and chronic rhinosinusitis, particularly focusing on patients with nasal polyps. The study involved 105 participants divided into three groups: those with eosinophilic polyps, those with neutrophilic polyps, and a control group of individuals who underwent surgery for reasons other than polyposis.

We measured the serum zinc concentrations in these groups to see if there were any significant differences. Our findings revealed that patients suffering from chronic rhinosinusitis and having neutrophilic polyps had notably lower zinc levels compared to the general population. However, the zinc levels in patients with eosinophilic polyps did not show a significant difference when compared to healthy controls.

While we saw a clear distinction in zinc levels between the neutrophilic group and the control group, the overall data suggests that zinc's role in sinusitis, especially for those with eosinophilic polyps, may not be as pronounced. As such, while zinc might contribute to inflammation in specific cases, its effectiveness as a standalone treatment for sinusitis remains uncertain.

Most Useful Reviews

9.5

Effective for colds

This is my go-to remedy! At the first sign of a cold, I take one tablet, and it has never let me down. I have chronic sinusitis and tonsillitis, and whenever I feel a runny nose or sore throat, I take the tablet before bed, and by morning, there’s no trace of the illness.

8.8

Quality ingredients

The quality of the ingredients is excellent. The package arrived within 15 days and has proven beneficial against rhinitis and sinusitis.