Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.4
USERS' SCORE
Good
Based on 28 Reviews
8.4
Supplement Facts
Serving Size: 2 Softgels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%**
Saturated Fat
0.5 g
3%**
Polyunsaturated Fat
1 g
†
Monounsaturated Fat
0.5 g
†
Fish Oil Concentrate
2 g (2,000 mg)
†
Eicosapentaenoic Acid (EPA)
360 mg
†
Docosahexaenoic Acid (DHA)
240 mg
†
Top Medical Research Studies
9
Eicosapentaenoic acid alleviates back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Read More
8
We conducted a study to see if omega-3 fatty acids, specifically sourced from Clupeonella grimmi fish oil, could help alleviate back pain associated with dysmenorrhoea. Our research involved a cross-over trial with 36 young women aged 18-22 years.
Participants were split into two groups: one group took 15 mL of fish oil each day, while the other received a placebo. After three months, we switched their treatments.
The results were quite compelling. Women who took the fish oil reported a significant drop in their pain levels on the visual analogue scale, scoring an average of 20.9 compared to 61.8 for those on the placebo. We also noticed a remarkable reduction in both low back and abdominal pain.
Furthermore, the use of fish oil allowed participants to need fewer ibuprofen doses for pain relief, suggesting its effectiveness in managing menstrual-related discomfort. Overall, our findings indicate that eicosapentaenoic acid can play a positive role in easing back pain during menstruation.
Participants were split into two groups: one group took 15 mL of fish oil each day, while the other received a placebo. After three months, we switched their treatments.
The results were quite compelling. Women who took the fish oil reported a significant drop in their pain levels on the visual analogue scale, scoring an average of 20.9 compared to 61.8 for those on the placebo. We also noticed a remarkable reduction in both low back and abdominal pain.
Furthermore, the use of fish oil allowed participants to need fewer ibuprofen doses for pain relief, suggesting its effectiveness in managing menstrual-related discomfort. Overall, our findings indicate that eicosapentaenoic acid can play a positive role in easing back pain during menstruation.
Read More
8
This study explored whether omega-3 fatty acids (n-3 FA) could slow down intervertebral disc degeneration, a common source of lower back pain. We induced disc degeneration in rats and then divided them into two groups—one received a daily diet enriched with omega-3s, while the other had a control diet.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
Read More
Most Useful Reviews
9
Eased back pain
96 people found this helpful
This vitamin is the best I have tried. As a chronic pain sufferer, I'm always looking for supplements to help. This one gives me an energy boost, and I am experiencing less back pain after taking it.
Read More
9
Eliminated back pain
90 people found this helpful
I've been taking this vitamin for a month now, and my back pain from work is gone. The quality of life improvement is worth the money.
Read More
9
Back pain relief
90 people found this helpful
I was suffering from lower back pain, but after taking this vitamin, I woke up the next day feeling stronger than ever!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.4
- All Researches
9
Eicosapentaenoic acid alleviates back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Read More
8
We investigated whether l-serine and EPA could help relieve chronic low-back and knee pain in adults. In a well-structured study with 120 participants, half received a combination of these compounds while the other half received a placebo. After eight weeks, results showed that those taking l-serine and EPA experienced significant pain relief.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
Read More
8
This study explored whether omega-3 fatty acids (n-3 FA) could slow down intervertebral disc degeneration, a common source of lower back pain. We induced disc degeneration in rats and then divided them into two groups—one received a daily diet enriched with omega-3s, while the other had a control diet.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
Read More
8
We conducted a study to see if omega-3 fatty acids, specifically sourced from Clupeonella grimmi fish oil, could help alleviate back pain associated with dysmenorrhoea. Our research involved a cross-over trial with 36 young women aged 18-22 years.
Participants were split into two groups: one group took 15 mL of fish oil each day, while the other received a placebo. After three months, we switched their treatments.
The results were quite compelling. Women who took the fish oil reported a significant drop in their pain levels on the visual analogue scale, scoring an average of 20.9 compared to 61.8 for those on the placebo. We also noticed a remarkable reduction in both low back and abdominal pain.
Furthermore, the use of fish oil allowed participants to need fewer ibuprofen doses for pain relief, suggesting its effectiveness in managing menstrual-related discomfort. Overall, our findings indicate that eicosapentaenoic acid can play a positive role in easing back pain during menstruation.
Participants were split into two groups: one group took 15 mL of fish oil each day, while the other received a placebo. After three months, we switched their treatments.
The results were quite compelling. Women who took the fish oil reported a significant drop in their pain levels on the visual analogue scale, scoring an average of 20.9 compared to 61.8 for those on the placebo. We also noticed a remarkable reduction in both low back and abdominal pain.
Furthermore, the use of fish oil allowed participants to need fewer ibuprofen doses for pain relief, suggesting its effectiveness in managing menstrual-related discomfort. Overall, our findings indicate that eicosapentaenoic acid can play a positive role in easing back pain during menstruation.
Read More
8
We explored the connection between docosahexaenoic acid (DHA) and back pain. This study aimed to understand if higher levels of omega-3 fatty acids, like DHA, can lead to less frequent or intense back pain.
Using robust data from previous genome-wide association studies, we found that increased levels of circulating omega-3 fatty acids were linked to a lower risk of experiencing lower back pain and sciatica. This suggests that incorporating more omega-3 fatty acids in our diet could potentially help alleviate some of the discomfort associated with back pain.
Our analysis also pointed out that individuals with higher omega-3 levels experienced less abdominal and pelvic pain, alongside the benefits for back pain. It’s exciting to think about how simple dietary adjustments could contribute to managing chronic pain effectively.
Using robust data from previous genome-wide association studies, we found that increased levels of circulating omega-3 fatty acids were linked to a lower risk of experiencing lower back pain and sciatica. This suggests that incorporating more omega-3 fatty acids in our diet could potentially help alleviate some of the discomfort associated with back pain.
Our analysis also pointed out that individuals with higher omega-3 levels experienced less abdominal and pelvic pain, alongside the benefits for back pain. It’s exciting to think about how simple dietary adjustments could contribute to managing chronic pain effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 28 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eased back pain
96 people found this helpful
This vitamin is the best I have tried. As a chronic pain sufferer, I'm always looking for supplements to help. This one gives me an energy boost, and I am experiencing less back pain after taking it.
Read More
9
Eliminated back pain
90 people found this helpful
I've been taking this vitamin for a month now, and my back pain from work is gone. The quality of life improvement is worth the money.
Read More
9
Back pain relief
90 people found this helpful
I was suffering from lower back pain, but after taking this vitamin, I woke up the next day feeling stronger than ever!
Read More
9
No more back pain
49 people found this helpful
I noticed that menstrual pain is gone after starting Omega-3, making it easier without painkillers. My health is also good!
Read More
9
Improved back pain
19 people found this helpful
Surprisingly, Omega-3 has been refreshing. By the second capsule, I felt health improvements, including less back pain and easier mornings. For $9.95, it’s the best quality supplement I’ve found.
Read More
Frequently Asked Questions
9
Back pain relief
90 people found this helpful
I was suffering from lower back pain, but after taking this vitamin, I woke up the next day feeling stronger than ever!
9
Overall health improvement
1 people found this helpful
I loved this product! After two weeks, my lower back pain and other discomforts were gone, and I felt great. I take two capsules daily, though I didn't notice any weight loss effects.
9
Eliminated knee pain
2 people found this helpful
I purchased Omega 3 on my rheumatologist's advice for knee pain. After a month of taking two capsules daily along with vitamin D3, I realised my back pain had disappeared. I'm very pleased with the product's quality.
9
Eased back pain
96 people found this helpful
This vitamin is the best I have tried. As a chronic pain sufferer, I'm always looking for supplements to help. This one gives me an energy boost, and I am experiencing less back pain after taking it.
9
Eliminated back pain
90 people found this helpful
I've been taking this vitamin for a month now, and my back pain from work is gone. The quality of life improvement is worth the money.
9
Reduced body pain
1 people found this helpful
I heard that taking this with calcium and vitamin D could alleviate my chronic body pain. Thanks to this, I've experienced less discomfort, including my back pain.
6
Easier menstruation
1 people found this helpful
I took two Omega 3 capsules before bed and found it easier to swallow. After a few trials, I discovered this timing worked best for me. I also noticed relief from back pain and muscle discomfort, which I couldn’t previously express. I’m incredibly pleased!
7
We examined the connection between the levels of omega-3 and omega-6 fatty acids in the blood and chronic pain conditions like lower back pain. In our study of 503 adults, we found that a higher ratio of omega-6 to omega-3 was linked to increased odds of experiencing both low back pain and temporomandibular disorder.
Interestingly, while men benefited from higher levels of omega-3 causing lower pain likelihood, the same effect wasn't seen for women. Overall, our findings suggest that omega-3 could play a role in managing back pain, although the results vary by gender.
Interestingly, while men benefited from higher levels of omega-3 causing lower pain likelihood, the same effect wasn't seen for women. Overall, our findings suggest that omega-3 could play a role in managing back pain, although the results vary by gender.
8
This study explored whether omega-3 fatty acids (n-3 FA) could slow down intervertebral disc degeneration, a common source of lower back pain. We induced disc degeneration in rats and then divided them into two groups—one received a daily diet enriched with omega-3s, while the other had a control diet.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
After a month, we noted a decrease in inflammation markers in the omega-3 group. Furthermore, MRI scans showed better hydration in their discs and histological assessments indicated less tissue damage. These findings suggest that omega-3 supplementation could be beneficial for back pain related to disc degeneration.
9
Eicosapentaenoic acid alleviates back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
7
We explored the effectiveness of omega-3 fish oil supplements as an alternative treatment for nonsurgical neck and back pain. Over a period from March to June 2004, we asked 250 patients to take 1200 mg of omega-3 fatty acids daily. After about a month, a questionnaire revealed that 60% of participants reported improvement in their overall pain and joint pain. A significant number even stopped using traditional NSAIDs, with over 88% expressing the desire to continue taking fish oil. Overall, our findings suggest that fish oil could be a safer option for managing pain without notable side effects.
8
We investigated whether l-serine and EPA could help relieve chronic low-back and knee pain in adults. In a well-structured study with 120 participants, half received a combination of these compounds while the other half received a placebo. After eight weeks, results showed that those taking l-serine and EPA experienced significant pain relief.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
This suggests that these compounds could be beneficial for individuals suffering from chronic pain, improving their overall quality of life. However, as with all treatments, individual results may vary.
References
- Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions. J Pain. 2023;24:478. doi:10.1016/j.jpain.2022.10.008
- Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Omega-6 and Omega-3 Polyunsaturated Fatty Acids in Painful Temporomandibular Disorder and Low Back Pain. J Pain. 2022;23:1724. doi:10.1016/j.jpain.2022.05.008
- Sasahara I, Yamamoto A, Takeshita M, Suga Y, Suzuki K, et al. l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J Nutr. 2020;150:2278. doi:10.1093/jn/nxaa156
- NaPier Z, Kanim LEA, Arabi Y, Salehi K, Sears B, et al. Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration. Med Sci Monit. 2019;25:9531. doi:10.12659/MSM.918649
- Maroon JC, Bost JW. Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain. Surg Neurol. 2006;65:326.
- Lin Z, Ni L, Teng C, Zhang Z, Wu L, et al. Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis. Front Cell Dev Biol. 2021;9:745621. doi:10.3389/fcell.2021.745621
- Kawabata F, Tsuji T. Effects of dietary supplementation with a combination of fish oil, bilberry extract, and lutein on subjective symptoms of asthenopia in humans. Biomed Res. 2011;32:387.
- Moghadamnia AA, Mirhosseini N, Abadi MH, Omranirad A, Omidvar S. Effect of Clupeonella grimmi (anchovy/kilka) fish oil on dysmenorrhoea. East Mediterr Health J. 2010;16:408.
- Dai Y, Chen Y, Gu R, Zhang C, Jiang R. Causal association of polyunsaturated fatty acids with chronic pain: a two-sample Mendelian randomization study. Front Nutr. 2023;10:1265928. doi:10.3389/fnut.2023.1265928
