We investigated the link between plasma omega-3 levels and the risk of heart failure (HF) in a large UK cohort study. Our analysis revealed that higher omega-3 levels were associated with a 21% lower chance of developing HF over nearly 14 years.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
Read More
9
Omega-3 reduces cardiovascular risk
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
We observed the effects of icosapent ethyl on heart health in a significant clinical trial involving statin-treated patients at high risk for cardiovascular events. This post hoc analysis revealed that icosapent ethyl reduced major cardiovascular issues, regardless of whether patients had low-density lipoprotein cholesterol (LDL-C) levels below or above 55 mg/dL.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Read More
8
Eicosapentaenoic acid reduces arrhythmia
Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice.
We explored the impact of eicosapentaenoic acid (EPA) on heart health by studying mice on a high-fat diet. Those supplemented with EPA showed a significant reduction in atrial fibrillation compared to those without. While 100% of the high-fat diet mice developed atrial fibrillation, only 50% of those receiving EPA did, and their episodes were shorter.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Read More
Most Useful Reviews
7.5
Supports cardiovascular health
491 people found this helpful
Strengthening the cardiovascular system, Omegas from this company have been incredibly effective for me! Each product has its merits, and this one stands out for support in the cardiovascular system due to its high EPA content. For brain activity enhancement, opt for Omega with higher DHA, although this also has a substantial DHA level. Please like if you found my review helpful!
Read More
9
Lowers bad cholesterol
240 people found this helpful
Omega-3 is excellent for reducing the risk of cardiovascular disease; it combats bad cholesterol and regulates blood pressure. It aids in weight control and promotes hair health. After extended use, I've noticed my hair quality improved and my bad cholesterol decreased slightly. This Omega thins the blood well, beneficial for my heart. After starting Omega, my hair has shone and split less.
Read More
9
Improves vascular health
122 people found this helpful
Omega-3, identified by Danish scientist Dayerberbu, shows that northern peoples' fish-based diets contribute to longevity and health. These fatty acids prevent cardiovascular disease and improve metabolic processes. A shortage of omega-3 can lead to dangerous cholesterol levels. Omega-3 enhances blood vessel elasticity, may prevent allergic and skin diseases, and has antioxidant properties, reducing cancer risk. If you found this review helpful, please click YES!
We observed the effects of icosapent ethyl on heart health in a significant clinical trial involving statin-treated patients at high risk for cardiovascular events. This post hoc analysis revealed that icosapent ethyl reduced major cardiovascular issues, regardless of whether patients had low-density lipoprotein cholesterol (LDL-C) levels below or above 55 mg/dL.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Read More
9
Omega-3 improves heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
We assessed how omega-3 fatty acids (PUFAs) can support heart failure management through a thorough network meta-analysis of 14 studies with nearly 9,100 participants.
Our findings revealed that high doses (2,000-4,000 mg/day) taken for at least one year significantly improved heart function, particularly the left ventricular ejection fraction and peak oxygen consumption.
However, lower doses and shorter durations were not effective, and we found no major differences in safety measures like dropout rates or overall mortality between those taking omega-3 and those who were not.
Read More
9
Omega-3 levels reduce heart failure
Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities.
We investigated the link between plasma omega-3 levels and the risk of heart failure (HF) in a large UK cohort study. Our analysis revealed that higher omega-3 levels were associated with a 21% lower chance of developing HF over nearly 14 years.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
Read More
9
Krill oil may improve heart health
Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice.
We delved into how Antarctic krill oil, rich in eicosapentaenoic acid (EPA), can influence cardiovascular health, specifically in the context of obesity. Our focus centered on its effects in mice fed a high-fat diet, which typically leads to increased cholesterol levels and oxidative stress—conditions that can heighten cardiovascular disease risk.
Through our research methods, including molecular docking and analysis of liver histology, we discovered that Antarctic krill oil appears to play a beneficial role in combating these adverse effects. We observed that the oil reduced oxidative stress and fat accumulation in these obese mice. This was associated with improved metabolic parameters that contribute to heart health, primarily through its action on molecules involved in cholesterol metabolism.
Notably, we found that krill oil helped lower the levels of harmful low-density lipoprotein cholesterol and activated pathways that support good cholesterol management in the body. These findings suggest that incorporating Antarctic krill oil, with its high EPA content, might be a promising strategy for addressing obesity-related cardiovascular issues.
Overall, our study points to the potential of eicosapentaenoic acid from krill oil as a natural approach to improving heart health, particularly for those struggling with obesity and its challenges.
Read More
8
Omega-3s are safer for hearts
EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines.
This study examined how different fatty acids affect heart health, particularly focusing on long-chain acylcarnitines. We found that saturated and monounsaturated acylcarnitines, especially one type called trans-elaidoylcarnitine, can significantly harm heart function and cell viability.
On the other hand, omega-3 derived acylcarnitines like eicosapentaenoylcarnitine and docosahexaenoylcarnitine showed minimal negative effects. In fact, they did not impair heart function or cell viability, suggesting that omega-3 fish oil might be a safer option for people with heart issues compared to other fatty acid sources.
Strengthening the cardiovascular system, Omegas from this company have been incredibly effective for me! Each product has its merits, and this one stands out for support in the cardiovascular system due to its high EPA content. For brain activity enhancement, opt for Omega with higher DHA, although this also has a substantial DHA level. Please like if you found my review helpful!
Read More
9
Lowers bad cholesterol
240 people found this helpful
Omega-3 is excellent for reducing the risk of cardiovascular disease; it combats bad cholesterol and regulates blood pressure. It aids in weight control and promotes hair health. After extended use, I've noticed my hair quality improved and my bad cholesterol decreased slightly. This Omega thins the blood well, beneficial for my heart. After starting Omega, my hair has shone and split less.
Read More
9
Improves vascular health
122 people found this helpful
Omega-3, identified by Danish scientist Dayerberbu, shows that northern peoples' fish-based diets contribute to longevity and health. These fatty acids prevent cardiovascular disease and improve metabolic processes. A shortage of omega-3 can lead to dangerous cholesterol levels. Omega-3 enhances blood vessel elasticity, may prevent allergic and skin diseases, and has antioxidant properties, reducing cancer risk. If you found this review helpful, please click YES!
Read More
9
Heart disease control
70 people found this helpful
This fish oil is fantastic! My family takes two capsules daily. Omega 3 is vital for preventing cardiovascular disease and also enhances brain function and immune response. The quality and affordability make NOW Foods a great choice.
Read More
9
Effective against disease
36 people found this helpful
Omega-3 is one of the best options for combating cardiovascular disease. I prioritise my health and that of my loved ones, so I choose it with confidence.
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
Omega-3 fish oil has long been touted for its potential cardiovascular benefits, and numerous studies support the notion that it can be helpful in managing overall heart health. Rich in EPA and DHA, the primary active components in fish oil, omega-3 fatty acids are known to reduce triglyceride levels, lower blood pressure, and may even decrease the risk of arrhythmias. Some research suggests that regular consumption of omega-3s can lead to a reduced risk of heart disease and stroke by improving vascular health and reducing inflammation in the body.
However, it's essential to approach this topic with a balanced perspective. While omega-3 supplements can be beneficial, they should not be seen as a standalone solution for cardiovascular disease. Incorporating omega-3s through diet—such as fatty fish like salmon, sardines, and mackerel—is preferable to relying solely on supplements. Moreover, if you're considering adding fish oil supplements to your routine, it's advisable to consult with a healthcare provider to ensure they fit within your complete cardiovascular health strategy, which should also include a nutritious diet, regular exercise, and other heart-healthy lifestyle choices.
Based on user reviews, the time it takes to see results from taking Omega-3 supplements for cardiovascular disease can vary significantly. Many users report feeling noticeable effects within a month. For instance, one reviewer mentioned a decrease in discomfort and improved blood pressure stability after just 30 days of taking Omega-3 Read Review. Another user experienced improvements in vision and lubrication in their eyes within a week of starting to take the supplement Read Review.
Overall, while some users experience benefits like improved cholesterol levels and enhanced heart function relatively quickly, others may find that it takes continuous use over several months to fully appreciate the cardiovascular benefits of Omega-3 Read Review. Therefore, it seems wise to maintain a consistent regimen for optimal effects, keeping in mind individual responses may differ.
Research strongly supports the use of omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in promoting cardiovascular health. Various studies have consistently linked the intake of these fatty acids to a reduced risk of heart disease and improvements in heart function. For example, a large cohort study indicated that higher omega-3 levels were associated with a 21% decreased risk of heart failure, while another found that EPA supplementation significantly reduced major cardiovascular events in high-risk patients [22]. This evidence suggests that omega-3 supplementation can be a valuable intervention for individuals looking to enhance their heart health.
Moreover, findings from studies examining the impact of omega-3 diets highlight their meaningful effects on lowering cholesterol levels, reducing blood pressure, and decreasing inflammation—all crucial factors in cardiovascular disease management [4]. Collectively, this body of evidence emphasizes the potential of omega-3 supplements as a proactive strategy for supporting heart health and mitigating cardiovascular risks. As with any supplement, though, it's essential to consult healthcare professionals before starting a regimen, especially for those with existing health conditions.
Based on user reviews, many individuals report marked improvements in various health symptoms after taking Omega-3 supplements. Users frequently note enhancements related to cardiovascular health, such as lower bad cholesterol levels and improved blood pressure stability. One user shared their experience of easing discomfort and achieving more stable blood pressure after a month of use Read Review. Additionally, several reviews indicate that Omega-3 can improve skin quality, support joint mobility, and even enhance hair health over time, suggesting a multi-faceted approach to wellness Read Review.
Users also report cognitive benefits, such as enhanced memory and focus, alongside physical health improvements. One reviewer mentioned a significant boost in vision and lubrication of the eyes within just a week of starting the supplement Read Review. Overall, while it's clear that many have experienced positive results—from enhanced heart health to improved cognitive function—responses to Omega-3 can vary from person to person, underscoring that individual results may differ significantly.
Based on user reviews, many individuals feel that combining Omega-3 supplements with other dietary supplements can yield substantial benefits for managing cardiovascular health. Several users reported that they complement their Omega-3 intake with vitamins or additional health supplements to enhance overall wellness. For example, one reviewer mentioned taking Omega-3 for cardiovascular support and also noted the importance of consulting a doctor regarding additional supplements Read Review. This indicates that users are often open to integrating Omega-3 with other supplements to optimize their health outcomes.
Additionally, reviews highlight that Omega-3 itself is often taken alongside other nutrients that promote heart health, such as vitamins that enhance absorption or support metabolic processes. One reviewer pointed out that they prefer Omega-3 options over other combinations due to its effectiveness in reducing cardiovascular risks, suggesting a tailored supplementation strategy Read Review. This implies a trend toward strategic combinations of supplements among users aiming to bolster their cardiovascular health.
When it comes to Omega-3 fish oil for treating cardiovascular disease, research suggests that high doses ranging from 2,000 to 4,000 mg per day are optimal. A comprehensive meta-analysis involving nearly 9,000 participants indicated that these higher doses, when sustained for at least one year, significantly improved heart function parameters, like left ventricular ejection fraction and peak oxygen consumption. Lower doses, unfortunately, did not yield similar cardiovascular benefits, reinforcing the idea that quantity matters in supplementation ([7]).
Additionally, another study focused on the effectiveness of eicosapentaenoic acid (EPA), a prominent Omega-3 fatty acid, noted its role in reducing major cardiovascular events in patients who were already at high risk due to other factors like statin use. This underpins the broader consensus within the research community regarding the importance of adequate Omega-3 intake in managing heart health, especially for patients with pre-existing cardiovascular conditions ([5]).
8
Reduced inflammation
22 people found this helpful
Due to work-related issues and persistent joint inflammation, my doctors advised high-dose fish oil for inflammation reduction. Scientific journals recommend adults over 50 to take over 1000mg of fish oil, especially those with circulatory issues. After a month of taking Omega 3, my discomfort has eased, and my blood pressure is more stable. I plan to keep purchasing it as the price is reasonable.
9
Improves vision health
5 people found this helpful
I felt effects on my vision quickly after buying this Omega-3 for cardiovascular support. After just one week of taking 4 capsules daily, I noticed significant lubrication in my eyes and improvement in vision. I could read without glasses, even in low light. It’s a quality product that works!
9
Lowers bad cholesterol
240 people found this helpful
Omega-3 is excellent for reducing the risk of cardiovascular disease; it combats bad cholesterol and regulates blood pressure. It aids in weight control and promotes hair health. After extended use, I've noticed my hair quality improved and my bad cholesterol decreased slightly. This Omega thins the blood well, beneficial for my heart. After starting Omega, my hair has shone and split less.
9
Supports cardiovascular health
7 people found this helpful
Excellent! Everyone needs Omega 3! I order several jars for the family. The capsules are easy to swallow. Great packaging at a good price. We often don’t get enough fatty acids from food. Therefore, taking Omega 3 is essential! It supports cardiovascular disease, immunity, and improves brain function. Do consult your doctor first!
8
Strengthens heart health
10 people found this helpful
Currently, the omega-3 options are competitively priced. This supplement plays a critical role in enhancing cell membrane strength and overall cardiovascular health. Regular consumption is linked to lower cardiovascular risks. I prefer it over other combinations due to its effectiveness.
4
Exploring EPA's heart health effects
Relationship Between Serum ω-3 Polyunsaturated Fatty Acid Concentration and Fatty Acid Fraction of Epicardial Adipose Tissue in Patients With Cardiovascular Disease.
We explored the relationship between eicosapentaenoic acid (EPA) and cardiovascular health by examining patients undergoing heart surgery. The study included 21 individuals, comprised of both men and women with an average age of around 70. We focused on measuring the fatty acid fractions in epicardial adipose tissue (EAT), subcutaneous adipose tissue (SAT), and serum to understand how these relate to inflammation and heart disease.
Our findings revealed that while levels of docosahexaenoic acid (DHA) were higher in EAT compared to SAT, EPA levels showed a significant correlation with serum EPA concentrations. This suggests that the EPA found in the body is likely to influence its presence in EAT. Additionally, we noted that both ALA and EPA levels in EAT were linked to lower levels of TNFα, a marker of inflammation.
However, we didn't find significant differences in EPA levels across the different tissue types among patients with or without atherosclerotic heart disease. Overall, while EPA and ALA are associated with potential anti-inflammatory effects for cardiovascular disease patients, further efforts to enhance serum EPA levels may be necessary to see increased availability in EAT.
8
Diet and fish oil improve heart health
Reduction of cardiovascular risk factors by the diet - Evaluation of the MoKaRi concept by a parallel-designed randomized study.
We explored how dietary changes, particularly the MoKaRi diet, can impact cardiovascular health. In a 20-week study with 65 participants, individualized meal plans were combined with fish oil supplements to assess their effects on various cardiometabolic risk factors.
The results showcased significant reductions in cholesterol levels, body weight, and other critical indicators. Notably, those who incorporated fish oil saw even greater improvements in weight loss and blood sugar levels. This research suggests that pairing a healthy diet with fish oil can enhance cardiovascular outcomes.
9
Omega-3 improves heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
We assessed how omega-3 fatty acids (PUFAs) can support heart failure management through a thorough network meta-analysis of 14 studies with nearly 9,100 participants.
Our findings revealed that high doses (2,000-4,000 mg/day) taken for at least one year significantly improved heart function, particularly the left ventricular ejection fraction and peak oxygen consumption.
However, lower doses and shorter durations were not effective, and we found no major differences in safety measures like dropout rates or overall mortality between those taking omega-3 and those who were not.
9
Omega-3 reduces cardiovascular risk
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
We observed the effects of icosapent ethyl on heart health in a significant clinical trial involving statin-treated patients at high risk for cardiovascular events. This post hoc analysis revealed that icosapent ethyl reduced major cardiovascular issues, regardless of whether patients had low-density lipoprotein cholesterol (LDL-C) levels below or above 55 mg/dL.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
References
Liepinsh E, Gukalova B, Krims-Davis K, Kuka J, Leduskrasta A, et al. EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines. Biofactors. 2025;51:e70014. 10.1002/biof.70014
Medoro A, Graziano F, Cardinale G, Voccola S, Zotti T, et al. The influence of FADS1 and ELOVL2 genetic polymorphisms on polyunsaturated fatty acid composition in response to fish oil supplementation. Lipids Health Dis. 2025;24:102. 10.1186/s12944-025-02513-w
Horii K, Ono K, Sumi T, Higashihara M, Zaima N, et al. Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice. J Physiol Sci. 2025;75:100014. 10.1016/j.jphyss.2025.100014
Dawczynski C, Drobner T, Weidauer T, Schlattmann P, Kiehntopf M, et al. Reduction of cardiovascular risk factors by the diet - Evaluation of the MoKaRi concept by a parallel-designed randomized study. Lipids Health Dis. 2025;24:88. 10.1186/s12944-025-02500-1
Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. 10.1161/JAHA.124.038656
Mao Q, Tian X, Wang X, Xu H, Zhang Y, et al. Global burden of cardiovascular diseases attributable to diet low in seafood omega-3 fatty acids from 1990~2021 and forecasting the future trends: A population-based study. PLoS One. 2025;20:e0316767. 10.1371/journal.pone.0316767
Tseng PT, Zeng BY, Hsu CW, Liang CS, Stubbs B, et al. The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis. Adv Nutr. 2025;16:100366. 10.1016/j.advnut.2025.100366
Hemmati R, Bahrami Zanjanbar D, Shishesaz MI, Soleimani A, Yari T. The impact of Omega-3 supplementation on arrhythmia reduction in acute coronary syndrome patients: a randomized clinical trial. J Complement Integr Med. 2025;22:173. 10.1515/jcim-2024-0427
Wang Y, Wu G, Wang Y, Rehman A, Yu L, et al. Recent developments, challenges, and prospects of dietary omega-3 PUFA-fortified foods: Focusing on their effects on cardiovascular diseases. Food Chem. 2025;470:142498. 10.1016/j.foodchem.2024.142498
Dong S, Wang Y, Bian J, Chen H, Dong J, et al. The effect of omega-3 Polyunsaturated Fatty Acid (PUFA) prescription preparations on the prevention of clinical cardiovascular disease: a meta-analysis of RCTs. Nutr J. 2024;23:157. 10.1186/s12937-024-01051-y
Jawad MA, O'Keefe JH, Tintle N, O'Keefe EL, Franco WG, et al. Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities. Mayo Clin Proc. 2024;99:1895. 10.1016/j.mayocp.2024.08.007
Brosolo G, Da Porto A, Marcante S, Capilupi F, Bertin N, et al. The role for ω-3 polyunsaturated and short chain fatty acids in hypertension: An updated view on the interaction with gut microbiota. Eur J Pharmacol. 2024;985:177107. 10.1016/j.ejphar.2024.177107
Lee YQ, Tan KH, Chong MF. Biomarkers of PUFA and cardiovascular risk factors and events in healthy Asian populations: a systematic review. Br J Nutr. 2024;132:1474. 10.1017/S0007114524002708
Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. 10.1038/s44319-024-00271-x
Li ZH, Song WQ, Qiu CS, Li HM, Tang XL, et al. Fish oil supplementation, genetic susceptibility and risk of new-onset hypertension. Prev Med. 2024;189:108152. 10.1016/j.ypmed.2024.108152
Hamaya R, Cook NR, Sesso HD, Buring JE, Manson JE. A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events. Am J Clin Nutr. 2025. 10.1016/j.ajcnut.2025.02.028
Liboriussen C, Nygaard L, Jensen JD, Schmidt EB, Glerup RI, et al. Low Plasma Marine N-3 Polyunsaturated Fatty Acids are Associated with Increased Risk of Cardiovascular Events in Patients Treated with Maintenance Hemodialysis. J Ren Nutr. 2025. 10.1053/j.jrn.2025.02.001
Yunoki K, Matsumi H, Miyoshi T, Kubo M, Hata Y, et al. Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy. J Cardiovasc Dev Dis. 2025;12. 10.3390/jcdd12020060
Patil T, Gregory M, Savona N, Jarmukli N, Leonard CE. Evaluating the Real-World Safety of Icosapent Ethyl Versus Omega-3 Polyunsaturated Fatty Acid in Nationwide US Veterans Cohort: Examining Atrial Fibrillation and Bleeding Endpoints. Clin Drug Investig. 2025;45:69. 10.1007/s40261-024-01417-4
Kim JY, Kong SYJ, Jung E, Cho YS. Omega-3 Fatty Acids as Potential Predictors of Sudden Cardiac Death and Cardiovascular Mortality: A Systematic Review and Meta-Analysis. J Clin Med. 2024;14. 10.3390/jcm14010026
Lamon-Fava S. Associations between omega-3 fatty acid-derived lipid mediators and markers of inflammation in older subjects with low-grade chronic inflammation. Prostaglandins Other Lipid Mediat. 2025;176:106948. 10.1016/j.prostaglandins.2025.106948
Fukuda T, Nakajima T, Hasegawa T, Amano H, Arikawa T, et al. Relationship Between Serum ω-3 Polyunsaturated Fatty Acid Concentration and Fatty Acid Fraction of Epicardial Adipose Tissue in Patients With Cardiovascular Disease. Cureus. 2024;16:e73417. 10.7759/cureus.73417
O'Keefe EL, O'Keefe JH, Abuissa H, Metzinger M, Murray E, et al. Omega-3 and Risk of atrial fibrillation: Vagally-mediated double-edged sword. Prog Cardiovasc Dis. 2024. 10.1016/j.pcad.2024.11.003
Choi JH, Park SE, Kim S. Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice. Nutrients. 2024;16. 10.3390/nu16213614
So J, Yao JH, Magadmi R, Matthan NR, Lamon-Fava S. Sex differences in lipid mediators derived from omega-3 fatty acids in older individuals with low-grade chronic inflammation. Prostaglandins Leukot Essent Fatty Acids. 2024;203:102655. 10.1016/j.plefa.2024.102655
Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. 10.3389/fnut.2024.1423228
Follonier C, Rabassa G, Branca M, Carballo D, Koskinas K, et al. Eligibility for marine omega-3 fatty acid supplementation after acute coronary syndromes. Atheroscler Plus. 2024;58:1. 10.1016/j.athplu.2024.09.002
Koutsaliaris IK, Pantazi D, Tsouka AN, Argyropoulou O, Tellis CC, et al. Differential Effect of Omega-3 Fatty Acids on Platelet Inhibition by Antiplatelet Drugs In Vitro. Int J Mol Sci. 2024;25. 10.3390/ijms251810136
Ren Y, Chen B, Zhang H, Xu S. A cohort study reveals shared and distinct serum metabolic biomarkers for major adverse cardiovascular events in middle-aged and older adults. Geroscience. 2025. 10.1007/s11357-025-01544-6
Arghavani H, Bilodeau JF, Rudkowska I. Association Between Circulating Fatty Acids and Blood Pressure: A Review. Curr Nutr Rep. 2025;14:15. 10.1007/s13668-024-00602-3
Li J, Guo J, Yuen M, Yuen H, Peng Q. The comparative effects of ω-7 fatty acid-rich sea buckthorn oil and ω-3 fatty acid-rich DHA algal oil on improving high-fat diet-induced hyperlipidemia. Food Funct. 2025;16:1241. 10.1039/d4fo04961f
Berkowitz L, Echeverría G, Salazar C, Faúndez C, Coe CL, et al. Lipidomic Signature of Healthy Diet Adherence and Its Association with Cardiometabolic Risk in American Adults. Nutrients. 2024;16. 10.3390/nu16233995
Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, et al. Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis. Eur J Prev Cardiol. 2025;32:233. 10.1093/eurjpc/zwae315