'
SCIENTIFIC SCORE
Most Likely Effective
Based on 4 Researches
8
USERS' SCORE
Very Good
Based on 14 Reviews
8.6
Supplement Facts
Serving Size:   2 Softgels
Amount Per Serving
%DV
Calories
20
 
Total Fat
2 g
3%**
Saturated Fat
0.5 g
3%**
Polyunsaturated Fat
1 g
Monounsaturated Fat
0.5 g
Fish Oil Concentrate
2 g (2,000 mg)
Eicosapentaenoic Acid (EPA)
360 mg
Docosahexaenoic Acid (DHA)
240 mg

Top Medical Research Studies

9
Eicosapentaenoic Acid reduces eczema
Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial.
Highly relevant to eczema treatment
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.

Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.

Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Read More
9
Eicosapentaenoic acid improves eczema
Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum.
Therapeutic potential for eczema
We explored the effects of eicosapentaenoic acid (EPA) ethyl ester on symptoms of atopic dermatitis (AD), a common skin condition characterized by persistent itching and skin barrier dysfunction. In a carefully designed study using hairless mice on a special diet, we observed significant improvements in skin condition after administering EPA.

This study builds on previous findings that showed an increase in serum EPA levels from another omega-3 fatty acid, α-linolenic acid, which similarly helped restore skin health in mice with AD. When we administered EPA to the affected mice, we saw a marked alleviation in both itchy skin and barrier impairment.

A key finding was that the levels of covalently bound ceramides, essential lipids for maintaining our skin's barrier, were greatly reduced in the skin of the AD mice. With EPA treatment, these ceramides were restored, suggesting that EPA may play a crucial role in supporting skin health by improving these lipid levels.

Our findings point to the possible therapeutic application of EPA ethyl ester in treating human eczema, which could lead to effective new options for managing this often-challenging condition.
Read More
7
Eicosapentaenoic acid linked to eczema
Self-reported seafood intake and atopy in Japanese school-aged children.
Relevant study on EPA and eczema
We focused on understanding how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid found in fish, influences the prevalence of eczema among Japanese school-aged children. The study included 135 students with eczema, 136 with asthma, and 137 healthy controls, all from the fifth and eighth grades in Shunan, Japan.

Through questionnaires, we assessed the participants' dietary intake, specifically their fish consumption, and measured total serum IgE levels, a marker linked to allergic responses. The results indicated that those who consumed fatty or dried fish had a lower prevalence of eczema compared to others, highlighting the potential protective effect of fish in our diet.

Interestingly, we saw that only the levels of EPA in the blood had a negative association with eczema, meaning higher EPA levels may reduce the incidence of this condition. Despite these encouraging findings regarding EPA and eczema, we found that fish consumption did not have a significant effect on asthma.

Overall, our findings suggest that including more fish in the diet could be beneficial for reducing eczema in children, with EPA playing a key role in this protective effect.
Read More

Most Useful Reviews

7.5
Eczema management
My skin is fragile due to weak intestines, leading to issues like acne and eczema. Combining it with NOW Vitamin C and pantothenic acid has helped significantly since I began taking it. Previously, I struggled with eczema around my hands, which has improved notably. I appreciate Omega-3 and consider it essential for my well-being, especially in managing eczema.
Read More
9.5
Soothes eczema
Works perfectly for me, though I’m saddened that they no longer ship to Spain. I’ve taken it for years, and it effectively lowers inflammation and soothes my eczema.
Read More
9.5
Skin improvement
I bought fish oil for my husband, who has dry skin and eczema. After two weeks, his skin showed noticeable improvement!
Read More

Medical Researches

SCIENTIFIC SCORE
Most Likely Effective
Based on 4 Researches
8
9
Eicosapentaenoic Acid reduces eczema
Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial.
Highly relevant to eczema treatment
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.

Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.

Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Read More
9
Eicosapentaenoic acid improves eczema
Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum.
Therapeutic potential for eczema
We explored the effects of eicosapentaenoic acid (EPA) ethyl ester on symptoms of atopic dermatitis (AD), a common skin condition characterized by persistent itching and skin barrier dysfunction. In a carefully designed study using hairless mice on a special diet, we observed significant improvements in skin condition after administering EPA.

This study builds on previous findings that showed an increase in serum EPA levels from another omega-3 fatty acid, α-linolenic acid, which similarly helped restore skin health in mice with AD. When we administered EPA to the affected mice, we saw a marked alleviation in both itchy skin and barrier impairment.

A key finding was that the levels of covalently bound ceramides, essential lipids for maintaining our skin's barrier, were greatly reduced in the skin of the AD mice. With EPA treatment, these ceramides were restored, suggesting that EPA may play a crucial role in supporting skin health by improving these lipid levels.

Our findings point to the possible therapeutic application of EPA ethyl ester in treating human eczema, which could lead to effective new options for managing this often-challenging condition.
Read More
7
Eicosapentaenoic acid in eczema treatment
Ameliorative effects of squid phospholipids from Todarodes pacificus on atopic dermatitis-like lesions in NC/Nga mice.
Limited isolated effect noted
We examined the potential benefits of eicosapentaenoic acid (EPA) in treating eczema by analyzing squid phospholipids derived from Todarodes pacificus. The research utilized established models, including the rat paw edema model and an atopic dermatitis-like mouse model (NC/Nga mice), allowing us to assess the effectiveness of this treatment.

The squid phospholipids primarily contained essential fatty acids like docosahexaenoic acid (DHA), EPA, and arachidonic acid, which are believed to contribute to their anti-inflammatory properties. In our testing, squid phospholipids notably reduced skin inflammation in the mouse model, leading to improvements in dermatitis symptoms. However, we observed that while these phospholipids showed promising results, the isolated impact of EPA alone could not be definitively established due to the complexities of the treatment's composition.

Our findings indicate that while squid phospholipids, which include EPA, may help in the management of eczema, other components within them also play significant roles in their overall effectiveness. Therefore, further research will be necessary to isolate and clarify how eicosapentaenoic acid specifically influences eczema outcomes.
Read More
7
Eicosapentaenoic acid linked to eczema
Self-reported seafood intake and atopy in Japanese school-aged children.
Relevant study on EPA and eczema
We focused on understanding how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid found in fish, influences the prevalence of eczema among Japanese school-aged children. The study included 135 students with eczema, 136 with asthma, and 137 healthy controls, all from the fifth and eighth grades in Shunan, Japan.

Through questionnaires, we assessed the participants' dietary intake, specifically their fish consumption, and measured total serum IgE levels, a marker linked to allergic responses. The results indicated that those who consumed fatty or dried fish had a lower prevalence of eczema compared to others, highlighting the potential protective effect of fish in our diet.

Interestingly, we saw that only the levels of EPA in the blood had a negative association with eczema, meaning higher EPA levels may reduce the incidence of this condition. Despite these encouraging findings regarding EPA and eczema, we found that fish consumption did not have a significant effect on asthma.

Overall, our findings suggest that including more fish in the diet could be beneficial for reducing eczema in children, with EPA playing a key role in this protective effect.
Read More

User Reviews

USERS' SCORE
Very Good
Based on 14 Reviews
8.6
9.5
Soothes eczema
Works perfectly for me, though I’m saddened that they no longer ship to Spain. I’ve taken it for years, and it effectively lowers inflammation and soothes my eczema.
9.5
Hydrated skin
I take four pills daily to achieve 1200 mg of EPA/DHA. This dosage keeps my skin hydrated and assists with my eczema.
9.5
Skin improvement
I bought fish oil for my husband, who has dry skin and eczema. After two weeks, his skin showed noticeable improvement!
9.5
Eczema relief
I was initially sceptical about any fishy taste, but there’s hardly any! It significantly healed my eczema, and while I need to take four pills a day, I’ve adjusted my dosage. It also helps with muscle soreness and promotes hair growth.
8.8
Antioxidant properties
Omega-3 has been shown to have a curative effect on various body systems. It can help prevent cardiovascular and gastrointestinal diseases, and it improves memory and vision. A lack of Omega-3 can lead to atherosclerotic plaques. This supplement helps with skin issues like eczema, boosts immunity, and has antioxidant properties. I recommend it for better health.
Read More
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