Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 38 Researches
7.9
USERS' SCORE
Moderately Good
Based on 162 Reviews
7.9
Supplement Facts
Serving Size: 2 Softgels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%**
Saturated Fat
0.5 g
3%**
Polyunsaturated Fat
1 g
†
Monounsaturated Fat
0.5 g
†
Fish Oil Concentrate
2 g (2,000 mg)
†
Eicosapentaenoic Acid (EPA)
360 mg
†
Docosahexaenoic Acid (DHA)
240 mg
†
Top Medical Research Studies
9
We conducted a comprehensive trial to understand how different types of omega-3 fatty acids affect cholesterol levels and inflammation in adults struggling with high cholesterol.
Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.
Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.
Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.
Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.
Read More
9
Scallop oil significantly reduces cholesterol
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.
Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Read More
9
We examined how swapping a saturated fat diet for omega-3 polyunsaturated fatty acids (n-3PUFAs) affects cholesterol and bone health in hypercholesterolemic rats.
In our study, rats that shifted to an n-3PUFA diet saw a notable decrease in serum lipids. While the diet appeared to positively impact their bone loss linked to periodontitis, rats on the n-3PUFA diet showed results similar to those on a commercial diet, indicating no major advantage of fish oil over a balanced diet.
Overall, our findings suggest that while omega-3s can help with cholesterol, they don't offer significant improvements over typical diets in these conditions.
In our study, rats that shifted to an n-3PUFA diet saw a notable decrease in serum lipids. While the diet appeared to positively impact their bone loss linked to periodontitis, rats on the n-3PUFA diet showed results similar to those on a commercial diet, indicating no major advantage of fish oil over a balanced diet.
Overall, our findings suggest that while omega-3s can help with cholesterol, they don't offer significant improvements over typical diets in these conditions.
Read More
Most Useful Reviews
9
Immune system boost
253 people found this helpful
We consistently order these Omega-3 capsules. They have significantly strengthened our immune systems and normalised my mother's high cholesterol levels. They have no aftertaste and are easy to swallow, even for children. Their cost is very competitive, making them an excellent choice.
Read More
10
Lower cholesterol levels
210 people found this helpful
My husband has high cholesterol, prompting our doctor to recommend Omega-3 supplementation. We chose this product for its value, and he took two capsules daily. After 2.5 months, his cholesterol levels normalised. The benefits of this Omega are invaluable, and I believe ongoing use is essential.
Read More
9
Improved blood work
162 people found this helpful
I take omega-3 capsules for daily polyunsaturated fatty acid intake. They improve my immune and endocrine systems, lower my high cholesterol, and benefit my skin, hair, and nails. I take four capsules daily, combining them with vitamin D3.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 38 Researches
7.9
- All Researches
9
We aimed to understand how Antarctic krill oil (ESKO) affects cholesterol levels, particularly in relation to obesity. Through our study involving mice, we observed that ESKO helped reduce oxidative stress and improve cholesterol metabolism.
While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
Read More
9
CA-rich fish oils lower cholesterol
We investigated whether cetoleic acid (CA), a healthy fat found in certain fish, can help lower cholesterol levels in rodents. Our systematic review included 12 studies, assessing how CA-rich fish oils influenced total cholesterol compared to regular diets.
The results showed a significant reduction in cholesterol levels in rodents that consumed CA-rich oils. However, it’s important to note that the risk of bias in the studies varied, making our conclusions tentative. Overall, these findings suggest CA-rich fish oils could play a beneficial role in heart health, but further research in humans is needed.
The results showed a significant reduction in cholesterol levels in rodents that consumed CA-rich oils. However, it’s important to note that the risk of bias in the studies varied, making our conclusions tentative. Overall, these findings suggest CA-rich fish oils could play a beneficial role in heart health, but further research in humans is needed.
Read More
9
Scallop oil significantly reduces cholesterol
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.
Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Read More
9
We examined the role of eicosapentaenoic acid (EPA), specifically icosapent ethyl, in reducing cardiovascular disease risks. Approved by the FDA, this omega-3 treatment showed a notable 25% reduction in major heart events for high-risk patients. These patients already had controlled cholesterol but elevated triglyceride levels.
Importantly, while EPA proved effective, mixed omega-3 products lacking substantial evidence for heart health did not provide the same benefits. We believe adding EPA-only formulations to cardiovascular prevention guidelines is essential for at-risk individuals.
Importantly, while EPA proved effective, mixed omega-3 products lacking substantial evidence for heart health did not provide the same benefits. We believe adding EPA-only formulations to cardiovascular prevention guidelines is essential for at-risk individuals.
Read More
9
8-HEPE benefits cholesterol management
We explored how 8-hydroxyeicosapentaenoic acid (8-HEPE), derived from Pacific krill, could improve cholesterol levels in mice commonly used for dyslipidemia studies.
Over eighteen weeks, mice on a high-cholesterol diet receiving 8-HEPE showed significantly higher levels of good HDL cholesterol, alongside lower levels of bad LDL cholesterol and liver triglycerides.
This suggests that 8-HEPE may enhance lipid profiles and liver health by influencing certain genes in macrophages. While promising, further research is needed to confirm these benefits in humans.
Over eighteen weeks, mice on a high-cholesterol diet receiving 8-HEPE showed significantly higher levels of good HDL cholesterol, alongside lower levels of bad LDL cholesterol and liver triglycerides.
This suggests that 8-HEPE may enhance lipid profiles and liver health by influencing certain genes in macrophages. While promising, further research is needed to confirm these benefits in humans.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 162 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Immune system boost
253 people found this helpful
We consistently order these Omega-3 capsules. They have significantly strengthened our immune systems and normalised my mother's high cholesterol levels. They have no aftertaste and are easy to swallow, even for children. Their cost is very competitive, making them an excellent choice.
Read More
10
Lower cholesterol levels
210 people found this helpful
My husband has high cholesterol, prompting our doctor to recommend Omega-3 supplementation. We chose this product for its value, and he took two capsules daily. After 2.5 months, his cholesterol levels normalised. The benefits of this Omega are invaluable, and I believe ongoing use is essential.
Read More
9
Improved blood work
162 people found this helpful
I take omega-3 capsules for daily polyunsaturated fatty acid intake. They improve my immune and endocrine systems, lower my high cholesterol, and benefit my skin, hair, and nails. I take four capsules daily, combining them with vitamin D3.
Read More
9
Normal cholesterol
143 people found this helpful
These easy-to-swallow capsules have no fishy smell. After 2.5 months, blood tests showed my cholesterol level at a normal 5.6! This omega truly works.
Read More
9
Reduced health risks
122 people found this helpful
This omega-3 fights high cholesterol and normalises blood pressure, while also reducing obesity-related disease risks. The reasonable price means it lasts a long time.
Read More
Frequently Asked Questions
10
Lower cholesterol levels
210 people found this helpful
My husband has high cholesterol, prompting our doctor to recommend Omega-3 supplementation. We chose this product for its value, and he took two capsules daily. After 2.5 months, his cholesterol levels normalised. The benefits of this Omega are invaluable, and I believe ongoing use is essential.
9
Normal cholesterol
143 people found this helpful
These easy-to-swallow capsules have no fishy smell. After 2.5 months, blood tests showed my cholesterol level at a normal 5.6! This omega truly works.
9
Improvement observed
10 people found this helpful
This is one of my favourite Omega-3 supplements. I consume six capsules daily, and my cholesterol levels improved significantly. An intake of at least 3 grams daily is recommended for those with high cholesterol.
0
Did not lower
14 people found this helpful
The low price attracted me, but it did not lower my cholesterol. After taking it, my cholesterol increased slightly. Switching back to a concentrated product normalised my levels again. Higher concentration seems more effective for cholesterol management.
9
Improved blood work
162 people found this helpful
I take omega-3 capsules for daily polyunsaturated fatty acid intake. They improve my immune and endocrine systems, lower my high cholesterol, and benefit my skin, hair, and nails. I take four capsules daily, combining them with vitamin D3.
9
Reduced inflammation
22 people found this helpful
Due to occupational issues and ongoing joint inflammation, doctors recommended I take high-dose fish oil. After supplementing with Omega 3 for a month, my joint pain has improved, and my blood pressure stabilised. The reasonable price encourages me to continue using it.
9
Effective for cholesterol
9 people found this helpful
I bought this omega-3 for my husband due to his high cholesterol levels. He experienced positive impressions after taking it, and his bad cholesterol level dropped without medication! I combined it with vitamin D-3 and found it easy to use.
9
We examined the impact of a highly purified eicosapentaenoic acid (EPA) formulation on cholesterol levels and overall heart health in individuals considered at high risk for cardiovascular issues. The study involved 226 patients who had high triglycerides and one or more cardiovascular risk factors, such as hypertension or diabetes.
Participants received 4 grams of EPA daily for three months alongside regular nutritional counseling. By tracking key health markers, we noted significant improvements in cholesterol levels, particularly in triglycerides and low-density lipoprotein (LDL). For instance, triglyceride levels dropped from an average of 2.97 mmol/L to 1.75 mmol/L in just three months.
Additionally, we found improvements in other important metrics, including total cholesterol and glucose levels, indicating that EPA supplementation may have broad benefits for cardiometabolic health. Although apolipoprotein A levels did not change significantly, the overall trend suggests that incorporating EPA could play a role in achieving better heart health outcomes.
Participants received 4 grams of EPA daily for three months alongside regular nutritional counseling. By tracking key health markers, we noted significant improvements in cholesterol levels, particularly in triglycerides and low-density lipoprotein (LDL). For instance, triglyceride levels dropped from an average of 2.97 mmol/L to 1.75 mmol/L in just three months.
Additionally, we found improvements in other important metrics, including total cholesterol and glucose levels, indicating that EPA supplementation may have broad benefits for cardiometabolic health. Although apolipoprotein A levels did not change significantly, the overall trend suggests that incorporating EPA could play a role in achieving better heart health outcomes.
8
We examined the effects of eicosapentaenoic acid (EPA), an omega-3 fatty acid, on high cholesterol levels. In a systematic review of randomized controlled trials, we looked at studies involving at least 2 grams of EPA or its counterpart, docosahexaenoic acid (DHA).
Both EPA and DHA were found to lower triglyceride levels, with DHA appearing slightly more effective. Interestingly, we also saw that DHA increases high-density lipoprotein (HDL) cholesterol, which is known to promote heart health, while EPA does so as well, but to a lesser extent.
On the flip side, DHA has been observed to increase low-density lipoprotein (LDL) cholesterol, but it also enhances the size of LDL particles, making them less likely to contribute to artery blockages. Moreover, we noted that DHA might be more effective than EPA in reducing heart rate and blood pressure, which are essential factors in heart health.
Although both EPA and DHA show potential in promoting heart health by reducing inflammation and oxidative stress, the variations in their effects can make things complicated. We found that the evidence comparing EPA and DHA directly is limited, and more high-quality research is necessary to better understand their individual impacts on cholesterol and other cardiovascular risk factors.
Overall, while EPA has beneficial effects on cholesterol, further studies are needed to isolate these effects clearly from those of DHA.
Both EPA and DHA were found to lower triglyceride levels, with DHA appearing slightly more effective. Interestingly, we also saw that DHA increases high-density lipoprotein (HDL) cholesterol, which is known to promote heart health, while EPA does so as well, but to a lesser extent.
On the flip side, DHA has been observed to increase low-density lipoprotein (LDL) cholesterol, but it also enhances the size of LDL particles, making them less likely to contribute to artery blockages. Moreover, we noted that DHA might be more effective than EPA in reducing heart rate and blood pressure, which are essential factors in heart health.
Although both EPA and DHA show potential in promoting heart health by reducing inflammation and oxidative stress, the variations in their effects can make things complicated. We found that the evidence comparing EPA and DHA directly is limited, and more high-quality research is necessary to better understand their individual impacts on cholesterol and other cardiovascular risk factors.
Overall, while EPA has beneficial effects on cholesterol, further studies are needed to isolate these effects clearly from those of DHA.
9
We aimed to understand how Antarctic krill oil (ESKO) affects cholesterol levels, particularly in relation to obesity. Through our study involving mice, we observed that ESKO helped reduce oxidative stress and improve cholesterol metabolism.
While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
8
Omega-3s improve cholesterol and vascular health
We conducted a study to evaluate how high-dose eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) might affect cholesterol levels, particularly remnant-like lipoprotein cholesterol (RLP-C), and the ankle-brachial index (ABI) in hemodialysis patients struggling with dyslipidemia. Our research involved 38 participants who were divided into two groups: one received standard therapy alone, while the other received the same therapy plus the omega-3 supplements for three months. After the intervention, we took a closer look at how these treatments influenced cholesterol levels and vascular health.
The results were quite promising for those on the omega-3 regimen. The group that received EPA/DHA showed a significant reduction in RLP-C levels, with an average drop of about 3.25 mg/dL. In contrast, the control group experienced a small increase in cholesterol levels. Additionally, the omega-3 group also saw improvements in ABI measurements, indicating better peripheral arterial function. We discovered a noteworthy correlation, showing that the drops in cholesterol were connected to improvements in ABI.
In light of these findings, it appears that adding EPA/DHA can enhance standard treatment options for hemodialysis patients by lowering harmful cholesterol levels and improving vascular health. This suggests that healthcare providers should pay attention to RLP-C levels in these patients and consider omega-3 fatty acids as a viable option for managing cardiovascular risks.
The results were quite promising for those on the omega-3 regimen. The group that received EPA/DHA showed a significant reduction in RLP-C levels, with an average drop of about 3.25 mg/dL. In contrast, the control group experienced a small increase in cholesterol levels. Additionally, the omega-3 group also saw improvements in ABI measurements, indicating better peripheral arterial function. We discovered a noteworthy correlation, showing that the drops in cholesterol were connected to improvements in ABI.
In light of these findings, it appears that adding EPA/DHA can enhance standard treatment options for hemodialysis patients by lowering harmful cholesterol levels and improving vascular health. This suggests that healthcare providers should pay attention to RLP-C levels in these patients and consider omega-3 fatty acids as a viable option for managing cardiovascular risks.
8
We explored how eicosapentaenoic acid (EPA) impacts cholesterol, particularly focusing on its effects in patients with high triglyceride levels. Research indicates that hypertriglyceridaemia can contribute significantly to atherosclerotic cardiovascular disease (ASCVD), even in patients who have low levels of low-density lipoprotein cholesterol (LDL-C) due to treatments like statins.
While previous studies have shown mixed results regarding the effectiveness of triglyceride-lowering medications, EPA stands out in providing favorable outcomes for certain patient groups. It's worth noting that the combination of EPA with another substance, docosahexaenoic acid (DHA), has not demonstrated the same benefits.
The key takeaway is that while the search for efficient treatments continues, isolated EPA treatment has shown promise in reducing ASCVD risk, especially for patients struggling with high triglyceride levels. This suggests that as we develop our understanding of cholesterol management, EPA could be an important piece of the puzzle for those at risk.
While previous studies have shown mixed results regarding the effectiveness of triglyceride-lowering medications, EPA stands out in providing favorable outcomes for certain patient groups. It's worth noting that the combination of EPA with another substance, docosahexaenoic acid (DHA), has not demonstrated the same benefits.
The key takeaway is that while the search for efficient treatments continues, isolated EPA treatment has shown promise in reducing ASCVD risk, especially for patients struggling with high triglyceride levels. This suggests that as we develop our understanding of cholesterol management, EPA could be an important piece of the puzzle for those at risk.
References
- Choi JH, Park SE, Kim S. Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice. Nutrients. 2024;16. doi:10.3390/nu16213614
- Hirako S, Kim H, Iizuka Y, Matsumoto A. Fish oil consumption prevents hepatic lipid accumulation induced by high-cholesterol feeding in obese KK mice. Biomed Res. 2024;45:33. doi:10.2220/biomedres.45.33
- Mjaatveit M, Oldernes H, Gudbrandsen OA. Effects of diets containing fish oils or fish oil concentrates with high cetoleic acid content on the circulating cholesterol concentration in rodents. A systematic review and meta-analysis. Br J Nutr. 2024;131:606. doi:10.1017/S0007114523002118
- Zhang C, Wang X, Sun S, Fu Y, Wu Y, et al. Fat-1 expression alleviates atherosclerosis in transgenic rabbits. J Cell Mol Med. 2022;26:1306. doi:10.1111/jcmm.17188
- Sugimoto K, Hosomi R, Shimono T, Kanda S, Nishiyama T, et al. Comparison of the Cholesterol-Lowering Effect of Scallop Oil Prepared from the Internal Organs of the Japanese Giant Scallop (Patinopecten yessoensis), Fish Oil, and Krill Oil in Obese Type II Diabetic KK-A Mice. J Oleo Sci. 2021;70:965. doi:10.5650/jos.ess21032
- Jaca A, Durão S, Harbron J. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. S Afr Med J. 2020;110:1158. doi:10.7196/SAMJ.2020.v110i12.14730
- Trivedi K, Le V, Nelson JR. The case for adding eicosapentaenoic acid (icosapent ethyl) to the ABCs of cardiovascular disease prevention. Postgrad Med. 2021;133:28. doi:10.1080/00325481.2020.1783937
- Saito M, Ishida N, Yamada H, Ibi M, Hirose M. 8-HEPE-Concentrated Materials from Pacific Krill Improve Plasma Cholesterol Levels and Hepatic Steatosis in High Cholesterol Diet-Fed Low-Density Lipoprotein (LDL) Receptor-Deficient Mice. Biol Pharm Bull. 2020;43:919. doi:10.1248/bpb.b20-00162
- Llop-Talaveron J, Badía-Tahull M, Lozano-Andreu T, Rigo-Bonnin R, Virgili-Casas N, et al. Phytosterolemia and γ-glutamyl transferase in adults with parenteral nutrition: Fish versus vegetal lipids: A randomized clinical trial. Nutrition. 2020;70:110587. doi:10.1016/j.nut.2019.110587
- Antona ME, Ramos C, Stranges A, Monteiro AF, Gonzales Chaves MM, et al. Fish oil diet effects on alveolar bone loss, in hypercholesterolemic rats. Arch Oral Biol. 2020;109:104553. doi:10.1016/j.archoralbio.2019.104553
- Zhou Q, Zhang Z, Wang P, Zhang B, Chen C, et al. EPA+DHA, but not ALA, Improved Lipids and Inflammation Status in Hypercholesterolemic Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Mol Nutr Food Res. 2019;63:e1801157. doi:10.1002/mnfr.201801157
- Bhatt DL, Steg PG, Miller M, Brinton EA, Jacobson TA, et al. Effects of Icosapent Ethyl on Total Ischemic Events: From REDUCE-IT. J Am Coll Cardiol. 2019;73:2791. doi:10.1016/j.jacc.2019.02.032
- Preston Mason R. New Insights into Mechanisms of Action for Omega-3 Fatty Acids in Atherothrombotic Cardiovascular Disease. Curr Atheroscler Rep. 2019;21:2. doi:10.1007/s11883-019-0762-1
- Vikøren LA, Drotningsvik A, Bergseth MT, Mjøs SA, Austgulen MH, et al. Intake of Baked Cod Fillet Resulted in Lower Serum Cholesterol and Higher Long Chain -3 PUFA Concentrations in Serum and Tissues in Hypercholesterolemic Obese Zucker fa/fa Rats. Nutrients. 2018;10. doi:10.3390/nu10070840
- Blom WAM, Koppenol WP, Hiemstra H, Stojakovic T, Scharnagl H, et al. A low-fat spread with added plant sterols and fish omega-3 fatty acids lowers serum triglyceride and LDL-cholesterol concentrations in individuals with modest hypercholesterolaemia and hypertriglyceridaemia. Eur J Nutr. 2019;58:1615. doi:10.1007/s00394-018-1706-1
- Shen J, Rastogi R, Guan L, Li F, Du H, et al. Omega-3 fatty acid supplement reduces activation of NADPH oxidase in intracranial atherosclerosis stenosis. Neurol Res. 2018;40:499. doi:10.1080/01616412.2018.1451290
- Yunoki K, Matsumi H, Miyoshi T, Kubo M, Hata Y, et al. Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy. J Cardiovasc Dev Dis. 2025;12. doi:10.3390/jcdd12020060
- Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. doi:10.1161/JAHA.124.038656
- Uthaiah NM, Venkataramareddy SR, Mudhol S, Sheikh AY. EPA-rich Nannochloropsis oceanica biomass regulates gut microbiota, alleviates inflammation and ameliorates liver fibrosis in rats. Food Res Int. 2025;202:115733. doi:10.1016/j.foodres.2025.115733
- Yoshikiyo K, Shimizu H, Nagato EG, Ishizuka S, Yamamoto T. Comparative Analysis of γ-Cyclodextrin, Perilla Oil, and Their Inclusion Complexes on Liver Injury and Dyslipidemia Associated with Elevated Gastrointestinal 12-Hydroxylated Bile Acid Levels. Molecules. 2025;30. doi:10.3390/molecules30020281
- Lamantia V, Bissonnette S, Beaudry M, Cyr Y, Rosiers CD, et al. EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors. Sci Rep. 2024;14:27146. doi:10.1038/s41598-024-73672-6
- Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. doi:10.3389/fnut.2024.1423228
- Bashir B, Schofield J, Downie P, France M, Ashcroft DM, et al. Beyond LDL-C: unravelling the residual atherosclerotic cardiovascular disease risk landscape-focus on hypertriglyceridaemia. Front Cardiovasc Med. 2024;11:1389106. doi:10.3389/fcvm.2024.1389106
- Lin YL, Wang CL, Chiang TI. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients. Front Nephrol. 2024;4:1365809. doi:10.3389/fneph.2024.1365809
- Omari M, Alkhalil M. Atherosclerosis Residual Lipid Risk-Overview of Existing and Future Pharmacotherapies. J Cardiovasc Dev Dis. 2024;11. doi:10.3390/jcdd11040126
- Szarek M, Bhatt DL, Miller M, Brinton EA, Jacobson TA, et al. Lipoprotein(a) Blood Levels and Cardiovascular Risk Reduction With Icosapent Ethyl. J Am Coll Cardiol. 2024;83:1529. doi:10.1016/j.jacc.2024.02.016
- Liakos CI, Lanaras L, Bristianou M, Papadopoulos DP. Pleiotropic beneficial cardiometabolic actions of a high-purity eicosapentaenoic acid product in high cardiovascular risk individuals. Lipids. 2024;59:67. doi:10.1002/lipd.12391
- Ganuza E, Etomi EH, Olson M, Whisner CM. Omega-3 eicosapentaenoic polar-lipid rich extract from microalgae decreases plasma triglycerides and cholesterol in a real-world normolipidemic supplement consumer population. Front Nutr. 2024;11:1293909. doi:10.3389/fnut.2024.1293909
- Kobayashi Y, Fujikawa T, Haruna A, Kawano R, Ozawa M, et al. Omega-3 Fatty Acids Reduce Remnant-like Lipoprotein Cholesterol and Improve the Ankle-Brachial Index of Hemodialysis Patients with Dyslipidemia: A Pilot Study. Medicina (Kaunas). 2023;60. doi:10.3390/medicina60010075
- Mueller PA, Bergstrom P, Rosario S, Heard M, Pamir N. Fish Oil Supplementation Modifies the Proteome, Lipidome, and Function of High-Density Lipoprotein: Findings from a Trial in Young Healthy Adults. J Nutr. 2024;154:1130. doi:10.1016/j.tjnut.2024.01.007
- Kaur G, Mason RP, Steg PG, Bhatt DL. Omega-3 fatty acids for cardiovascular event lowering. Eur J Prev Cardiol. 2024;31:1005. doi:10.1093/eurjpc/zwae003
- Chang Y, Xuan Y, Zhang R, Ding X, Zeng Q, et al. Effects of Dietary Schizochytrium Algae as ω-3 PUFA Source on the Egg-Laying Quail Performance, Serum Indexes, and Egg Yolk Fatty Acids Contents. Animals (Basel). 2024;15. doi:10.3390/ani15010021
- Li J, Guo J, Yuen M, Yuen H, Peng Q. The comparative effects of ω-7 fatty acid-rich sea buckthorn oil and ω-3 fatty acid-rich DHA algal oil on improving high-fat diet-induced hyperlipidemia. Food Funct. 2025;16:1241. doi:10.1039/d4fo04961f
- Coelho-Júnior HJ, Álvarez-Bustos A, Picca A, Calvani R, Rodriguez-Mañas L, et al. Dietary Intake of Polyunsaturated Fatty Acids Is Associated with Blood Glucose and Diabetes in Community-Dwelling Older Adults. Nutrients. 2024;16. doi:10.3390/nu16234087
- Cabrita ARJ, Barroso C, Fontes-Sousa AP, Correia A, Teixeira L, et al. Assessing functional properties of diet protein hydrolysate and oil from fish waste on canine immune parameters, cardiac biomarkers, and fecal microbiota. Front Vet Sci. 2024;11:1449141. doi:10.3389/fvets.2024.1449141
- Zhang D, Wang Z, Guo S, Sun Y, Zhou D, et al. F-Fluorodeoxyglucose positron emission tomography/computed tomography imaging reveals the protective effect of docosahexaenoic acid on glucose metabolism by reducing brain 27-hydroxycholesterol. Exp Gerontol. 2024;196:112577. doi:10.1016/j.exger.2024.112577
- Zhao W, Wang Y, Li J, Chen T, Yin D, et al. Efficacy and safety of omega-3-acid ethyl acetate 90 capsules in severe hypertriglyceridemia: A randomized, controlled, multicenter study. Lipids. 2024;59:145. doi:10.1002/lipd.12406
- Li P, Khan S, Huang Y, Lu S, Zhou P, et al. Effect of Perilla seeds inclusion on the performance, egg quality characteristics, biochemical parameters and egg yolk fatty acid composition of laying hens. Trop Anim Health Prod. 2024;56:147. doi:10.1007/s11250-024-03983-3
