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NOW Supplements Alpha Lipoic Acid
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
250 mg
278%
Vitamin E (as d-alpha Tocopheryl Succinate)
20 mg
133%
Alpha Lipoic Acid
100 mg

Top Medical Research Studies

7
Vitamin C's role in arthritis management
The role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review.
Focused on vitamin C's benefits
We explored the role of vitamin C in addressing arthritis symptoms, particularly its effect on joint inflammation. Vitamin C is known for its antioxidant properties, and we found that it plays a crucial role in collagen synthesis. This feature is important as collagen forms the structural basis of our joints.

What excited us was the possibility that vitamin C could help reduce inflammation in patients with rheumatoid arthritis. Given that inflammation is a major factor in the discomfort and damage associated with this condition, any reduction could significantly enhance the quality of life for those affected.

However, while vitamin C shows promise due to its supportive functions, we must remember that the evidence concerning its direct effectiveness on arthritis specifically is still evolving. The correlation between vitamin C intake and reduced joint inflammation points to a beneficial role, but more detailed studies are necessary to solidify these findings and determine optimal dosages.

Overall, our review highlights that while vitamin C may indeed support joint health and aid in managing inflammation, further research is essential to fully understand its impact and to evaluate how it can be integrated into arthritis management strategies effectively.
Read More
8
Vitamin C's potential against arthritis
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
Effectiveness requires combination context
We explored the role of vitamin C (VC) in combating rheumatoid arthritis (RA) using a rat model. The study focused on how VC works in combination with inorganic nitrates to prevent arthritis symptoms, presenting an interesting angle on potential treatments for this chronic inflammatory disease.

Our observations revealed that when nitrates and VC were combined, they significantly reduced swelling and arthritis scores in the rats. This combination also appeared to lead to improvements in bone health and a decrease in inflammation markers in the body. Histological and radiological examinations indicated that the rats relieved from symptoms showed less synovial hyperplasia and bone loss.

Interestingly, while VC alone couldn’t be fully isolated for its effects, it contributed to reducing critical inflammation indicators such as TNF-α and IL-1β. By working together, nitrates and VC seem to effectively inhibit key inflammatory processes, particularly a type of cell death known as pyroptosis in macrophages. This suggests a promising new pathway for RA prevention, where the synergy between these two substances plays a crucial role.
Read More

Most Useful Reviews

8.8
Neuropathy alleviation
Great stuff! I used to suffer from intense nerve pain and cramps, which were debilitating. After consulting my rheumatologist for osteoarthritis and looking into alternative treatments, I started taking Alpha Lipoic Acid. This supplement has worked wonders; night cramps have vanished and the peripheral pain has significantly decreased. I'm extremely pleased with these results, and so is my rheumatologist.
Read More
9.5
Pain-free neuropathy
It must be magic. After reading positive feedback, I tried this supplement and was amazed at the results. My fingernails have become strong after just a few days, and my neuropathy and foot pain, including osteoarthritis discomfort, have notably improved. I've also eliminated my night-time leg cramps!
Read More
8.8
Eased nerve pain
Alpha Lipoic Acid has garnered attention for its ability to mitigate nerve pain, which I can attest to. I have been diagnosed with moderate to severe osteoarthritis, and dealing with severe nerve pain was arduous. Since taking Alpha Lipoic Acid daily, I've experienced calming effects on my nerves and relief from extreme pain. I'm optimistic about continuing this regimen; it’s a commendable product.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
8
Vitamin C's potential against arthritis
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
Effectiveness requires combination context
We explored the role of vitamin C (VC) in combating rheumatoid arthritis (RA) using a rat model. The study focused on how VC works in combination with inorganic nitrates to prevent arthritis symptoms, presenting an interesting angle on potential treatments for this chronic inflammatory disease.

Our observations revealed that when nitrates and VC were combined, they significantly reduced swelling and arthritis scores in the rats. This combination also appeared to lead to improvements in bone health and a decrease in inflammation markers in the body. Histological and radiological examinations indicated that the rats relieved from symptoms showed less synovial hyperplasia and bone loss.

Interestingly, while VC alone couldn’t be fully isolated for its effects, it contributed to reducing critical inflammation indicators such as TNF-α and IL-1β. By working together, nitrates and VC seem to effectively inhibit key inflammatory processes, particularly a type of cell death known as pyroptosis in macrophages. This suggests a promising new pathway for RA prevention, where the synergy between these two substances plays a crucial role.
Read More
7
Vitamin C's role in arthritis management
The role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review.
Focused on vitamin C's benefits
We explored the role of vitamin C in addressing arthritis symptoms, particularly its effect on joint inflammation. Vitamin C is known for its antioxidant properties, and we found that it plays a crucial role in collagen synthesis. This feature is important as collagen forms the structural basis of our joints.

What excited us was the possibility that vitamin C could help reduce inflammation in patients with rheumatoid arthritis. Given that inflammation is a major factor in the discomfort and damage associated with this condition, any reduction could significantly enhance the quality of life for those affected.

However, while vitamin C shows promise due to its supportive functions, we must remember that the evidence concerning its direct effectiveness on arthritis specifically is still evolving. The correlation between vitamin C intake and reduced joint inflammation points to a beneficial role, but more detailed studies are necessary to solidify these findings and determine optimal dosages.

Overall, our review highlights that while vitamin C may indeed support joint health and aid in managing inflammation, further research is essential to fully understand its impact and to evaluate how it can be integrated into arthritis management strategies effectively.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Neuropathy alleviation
Great stuff! I used to suffer from intense nerve pain and cramps, which were debilitating. After consulting my rheumatologist for osteoarthritis and looking into alternative treatments, I started taking Alpha Lipoic Acid. This supplement has worked wonders; night cramps have vanished and the peripheral pain has significantly decreased. I'm extremely pleased with these results, and so is my rheumatologist.
Read More
9.5
Pain-free neuropathy
It must be magic. After reading positive feedback, I tried this supplement and was amazed at the results. My fingernails have become strong after just a few days, and my neuropathy and foot pain, including osteoarthritis discomfort, have notably improved. I've also eliminated my night-time leg cramps!
Read More
8.8
Eased nerve pain
Alpha Lipoic Acid has garnered attention for its ability to mitigate nerve pain, which I can attest to. I have been diagnosed with moderate to severe osteoarthritis, and dealing with severe nerve pain was arduous. Since taking Alpha Lipoic Acid daily, I've experienced calming effects on my nerves and relief from extreme pain. I'm optimistic about continuing this regimen; it’s a commendable product.
Read More
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