' 
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.2
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
250 mg
278%
Vitamin E (as d-alpha Tocopheryl Succinate)
20 mg
133%
Alpha Lipoic Acid
100 mg
†
Top Medical Research Studies
9
Vitamin E may reduce blood clots
Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study.
High relevance to VTE treatment
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9
Vitamin C enhances blood clotting
Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b.
Highly relevant to blood clotting
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
Read More
9
Vitamin E aids blood clot resolution
Vitamin E improves fibrinolytic activity in patients with coronary spastic angina.
Significant results within study scope
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
Read More
Most Useful Reviews
8.8
Enhanced energy levels
Alpha-lipoic acid has truly been a blessing for my health and energy. Since I began taking it, I’ve noticed a significant boost in my overall well-being – more energy, improved mental clarity, and a lighter feeling. I'm particularly pleased that it helps regulate blood sugar levels, supporting a healthy metabolism. Additionally, it boasts antioxidant properties that protect cells from damage and slow ageing. This versatile supplement has greatly improved my health and recovery abilities.
Read More
8
Reduced fat storage
ALA markedly increases insulin sensitivity, leading to less insulin release from the pancreas, thereby lowering blood sugar. Insulin’s role as a "storage hormone" results in less fat storage due to lower insulin levels. Taking 2 capsules daily enables me to reach fasting blood sugar levels more quickly than without ALA and maintains stable blood sugar levels. It is a more effective and safer option compared to Ozempic!
Read More
7.5
Essential for management
I have been taking ALA for years to manage my blood sugar and can't imagine being without it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.2
- All Researches
9
Vitamin C aids tendon healing
The effect of fibrin clot and C vitamin on the surgical treatment of Achilles tendon injury in the rat model✰.
Demonstrates vitamin C effectiveness
In our investigation, we looked at how vitamin C, in combination with a fibrin clot, influences the healing of Achilles tendon injuries in rats. We used 52 adult Wistar-Albino rats and divided them into four distinct groups to assess various treatments.
The results showed that vitamin C, when paired with fibrin clot, significantly improved tendon healing. Not only did it enhance the mechanical strength of the tendon, but it also led to better histological and biochemical outcomes, suggesting a more robust healing process. We noted increased levels of important growth factors in the groups treated with fibrin clot and vitamin C.
Importantly, the findings indicated that vitamin C plays a beneficial role in recovery, especially when combined with other treatment strategies. While further research may be necessary to fully understand its isolated effects, the data suggests that vitamin C is a valuable component in the healing bundle for Achilles tendon injuries.
The results showed that vitamin C, when paired with fibrin clot, significantly improved tendon healing. Not only did it enhance the mechanical strength of the tendon, but it also led to better histological and biochemical outcomes, suggesting a more robust healing process. We noted increased levels of important growth factors in the groups treated with fibrin clot and vitamin C.
Importantly, the findings indicated that vitamin C plays a beneficial role in recovery, especially when combined with other treatment strategies. While further research may be necessary to fully understand its isolated effects, the data suggests that vitamin C is a valuable component in the healing bundle for Achilles tendon injuries.
Read More
9
Vitamin C enhances blood clotting
Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b.
Highly relevant to blood clotting
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
Read More
9
Tocotrienols reduce blood clot formation
Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries.
Highly relevant for cardiovascular health
Our exploration focused on how tocotrienols, a form of vitamin E, influence blood clotting, especially in the context of risk factors like stroke. Using a canine model, we assessed the effects of tocotrienols on platelet aggregation and thrombus formation.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
Read More
9
Vitamin E may reduce blood clots
Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study.
High relevance to VTE treatment
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9
Vitamin E shows limited blood clot impact
Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.
Preliminary findings on efficacy
We explored the effects of vitamin E and sesamin on blood pressure and blood clot formation using young rats prone to stroke. The rats were divided into four groups: a control group, a vitamin E group, a sesamin group, and a combination group for five weeks.
Notably, the rats receiving vitamin E and sesamin showed lower blood pressure and thrombotic tendencies compared to the control group. However, while there was some reduction in clot formation, it was not substantial enough to conclude a significant clinical benefit.
Thus, we observed that while vitamin E and sesamin may have some protective effects, their impact on blood clot prevention is not definitively established.
Notably, the rats receiving vitamin E and sesamin showed lower blood pressure and thrombotic tendencies compared to the control group. However, while there was some reduction in clot formation, it was not substantial enough to conclude a significant clinical benefit.
Thus, we observed that while vitamin E and sesamin may have some protective effects, their impact on blood clot prevention is not definitively established.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Enhanced energy levels
Alpha-lipoic acid has truly been a blessing for my health and energy. Since I began taking it, I’ve noticed a significant boost in my overall well-being – more energy, improved mental clarity, and a lighter feeling. I'm particularly pleased that it helps regulate blood sugar levels, supporting a healthy metabolism. Additionally, it boasts antioxidant properties that protect cells from damage and slow ageing. This versatile supplement has greatly improved my health and recovery abilities.
Read More
8
Reduced fat storage
ALA markedly increases insulin sensitivity, leading to less insulin release from the pancreas, thereby lowering blood sugar. Insulin’s role as a "storage hormone" results in less fat storage due to lower insulin levels. Taking 2 capsules daily enables me to reach fasting blood sugar levels more quickly than without ALA and maintains stable blood sugar levels. It is a more effective and safer option compared to Ozempic!
Read More
7.5
Essential for management
I have been taking ALA for years to manage my blood sugar and can't imagine being without it.
