Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
USERS' SCORE
Good
Based on 6 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
250 mg
278%
Vitamin E (as d-alpha Tocopheryl Succinate)
20 mg
133%
Alpha Lipoic Acid
100 mg
†
Top Medical Research Studies
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
Read More
8
We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
Read More
8
Vitamin C linked to reduced migraines
In our exploration of how dietary factors might influence migraine headaches, we examined the connection between vitamin C intake and headache intensity and frequency among women. The study included 265 participants who reported their dietary intake, and we focused particularly on their antioxidant quality score, which reflects the quality of their dietary antioxidants.
We observed noteworthy findings. Women with a higher dietary antioxidant quality score had significantly lower levels of migraine pain and fewer headache days. This trend was especially true for those who consumed more vitamin C. We found that higher vitamin C intake was associated with less severe headache pain, indicating that including more of this vitamin in our diets could potentially help alleviate migraine symptoms.
Furthermore, we noted that other antioxidants might also play a role, but vitamin C stood out in its association with reduced migraine severity. Overall, this research reinforces the idea that dietary choices, particularly those rich in vitamin C, could benefit those grappling with migraine headaches and should be closely monitored.
We observed noteworthy findings. Women with a higher dietary antioxidant quality score had significantly lower levels of migraine pain and fewer headache days. This trend was especially true for those who consumed more vitamin C. We found that higher vitamin C intake was associated with less severe headache pain, indicating that including more of this vitamin in our diets could potentially help alleviate migraine symptoms.
Furthermore, we noted that other antioxidants might also play a role, but vitamin C stood out in its association with reduced migraine severity. Overall, this research reinforces the idea that dietary choices, particularly those rich in vitamin C, could benefit those grappling with migraine headaches and should be closely monitored.
Read More
Most Useful Reviews
9
Reduced migraine frequency
99 people found this helpful
My neurologist, the director of the headache center at University of Pittsburgh Medical Center, recommended taking this daily. It has significantly reduced both the frequency and severity of my migraines.
Read More
0
Headaches developed
2 people found this helpful
Unfortunately, this brand caused headaches for me the morning after taking Alpha Lipoic Acid. Although I had used this brand before without issues, this instance was consistently problematic. I tried stopping and starting again multiple times, confirming that it was indeed the cause.
Read More
10
Headache relief
Fast delivery, high-quality and convenient packaging. The dosage is excellent, and the natural composition from herbal ingredients is commendable. The capsules are slightly large, but I have no trouble swallowing them, and they have a citrus taste. I take one capsule daily with meals, alongside vitamin D3+K2, magnesium, and vitamin B6. After just 10 days of use, I've noticed significant benefits; my energy levels have increased, headaches have ceased, and my mood is consistently positive. I highly recommend it, especially for those interested in sports, fitness, or dieting. Omega-3 is fantastic at replenishing what the body needs.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
- All Researches
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
Read More
8
We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
Read More
8
Vitamin C linked to reduced migraines
In our exploration of how dietary factors might influence migraine headaches, we examined the connection between vitamin C intake and headache intensity and frequency among women. The study included 265 participants who reported their dietary intake, and we focused particularly on their antioxidant quality score, which reflects the quality of their dietary antioxidants.
We observed noteworthy findings. Women with a higher dietary antioxidant quality score had significantly lower levels of migraine pain and fewer headache days. This trend was especially true for those who consumed more vitamin C. We found that higher vitamin C intake was associated with less severe headache pain, indicating that including more of this vitamin in our diets could potentially help alleviate migraine symptoms.
Furthermore, we noted that other antioxidants might also play a role, but vitamin C stood out in its association with reduced migraine severity. Overall, this research reinforces the idea that dietary choices, particularly those rich in vitamin C, could benefit those grappling with migraine headaches and should be closely monitored.
We observed noteworthy findings. Women with a higher dietary antioxidant quality score had significantly lower levels of migraine pain and fewer headache days. This trend was especially true for those who consumed more vitamin C. We found that higher vitamin C intake was associated with less severe headache pain, indicating that including more of this vitamin in our diets could potentially help alleviate migraine symptoms.
Furthermore, we noted that other antioxidants might also play a role, but vitamin C stood out in its association with reduced migraine severity. Overall, this research reinforces the idea that dietary choices, particularly those rich in vitamin C, could benefit those grappling with migraine headaches and should be closely monitored.
Read More
8
Vitamin E shows potential for migraines
We conducted a randomized, double-blind, sham-controlled pilot study to explore the effects of a combined antioxidant treatment—N-acetylcysteine, vitamin E, and vitamin C—on headaches in adults suffering from migraines.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
Read More
7
We explored how menopause affects headaches and the potential role of vitamin E in managing these symptoms. Among various treatment options, vitamin E emerged as one non-medication strategy that might help alleviate headaches related to hormonal changes during menopause. However, while some non-drug approaches like acupuncture and exercise show promise, there is limited evidence supporting the effectiveness of vitamin E specifically. We found that headaches can vary in frequency and severity during menopause, with many women experiencing little change in their headache status.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced migraine frequency
99 people found this helpful
My neurologist, the director of the headache center at University of Pittsburgh Medical Center, recommended taking this daily. It has significantly reduced both the frequency and severity of my migraines.
Read More
0
Headaches developed
2 people found this helpful
Unfortunately, this brand caused headaches for me the morning after taking Alpha Lipoic Acid. Although I had used this brand before without issues, this instance was consistently problematic. I tried stopping and starting again multiple times, confirming that it was indeed the cause.
Read More
10
Headache relief
Fast delivery, high-quality and convenient packaging. The dosage is excellent, and the natural composition from herbal ingredients is commendable. The capsules are slightly large, but I have no trouble swallowing them, and they have a citrus taste. I take one capsule daily with meals, alongside vitamin D3+K2, magnesium, and vitamin B6. After just 10 days of use, I've noticed significant benefits; my energy levels have increased, headaches have ceased, and my mood is consistently positive. I highly recommend it, especially for those interested in sports, fitness, or dieting. Omega-3 is fantastic at replenishing what the body needs.
Read More
6
Helps prevent headaches
26 people found this helpful
I rely on this to manage my hypoglycemia, avoiding sugar and junk foods. Along with GTF Chromium, these supplements help prevent headaches and other hypoglycemic symptoms.
Read More
7.5
Reduced headaches
2 people found this helpful
For detoxification, I manage the amount based on the half-life of Alpha lipoic acid, which is effective in eliminating heavy metals like mercury. The 100 mg dosage is useful for easy adjustments. Although lipoic acid and glutathione can cause headaches, I’ve learnt to follow the three-hour half-life and stay within limits to minimise this effect. Additionally, I appreciate that it includes vitamins C and E, which further support my health.
Read More
Frequently Asked Questions
10
Headache relief
Fast delivery, high-quality and convenient packaging. The dosage is excellent, and the natural composition from herbal ingredients is commendable. The capsules are slightly large, but I have no trouble swallowing them, and they have a citrus taste. I take one capsule daily with meals, alongside vitamin D3+K2, magnesium, and vitamin B6. After just 10 days of use, I've noticed significant benefits; my energy levels have increased, headaches have ceased, and my mood is consistently positive. I highly recommend it, especially for those interested in sports, fitness, or dieting. Omega-3 is fantastic at replenishing what the body needs.
7.5
Reduced headaches
2 people found this helpful
For detoxification, I manage the amount based on the half-life of Alpha lipoic acid, which is effective in eliminating heavy metals like mercury. The 100 mg dosage is useful for easy adjustments. Although lipoic acid and glutathione can cause headaches, I’ve learnt to follow the three-hour half-life and stay within limits to minimise this effect. Additionally, I appreciate that it includes vitamins C and E, which further support my health.
8
We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
8
Vitamin C linked to reduced migraines
In our exploration of how dietary factors might influence migraine headaches, we examined the connection between vitamin C intake and headache intensity and frequency among women. The study included 265 participants who reported their dietary intake, and we focused particularly on their antioxidant quality score, which reflects the quality of their dietary antioxidants.
We observed noteworthy findings. Women with a higher dietary antioxidant quality score had significantly lower levels of migraine pain and fewer headache days. This trend was especially true for those who consumed more vitamin C. We found that higher vitamin C intake was associated with less severe headache pain, indicating that including more of this vitamin in our diets could potentially help alleviate migraine symptoms.
Furthermore, we noted that other antioxidants might also play a role, but vitamin C stood out in its association with reduced migraine severity. Overall, this research reinforces the idea that dietary choices, particularly those rich in vitamin C, could benefit those grappling with migraine headaches and should be closely monitored.
We observed noteworthy findings. Women with a higher dietary antioxidant quality score had significantly lower levels of migraine pain and fewer headache days. This trend was especially true for those who consumed more vitamin C. We found that higher vitamin C intake was associated with less severe headache pain, indicating that including more of this vitamin in our diets could potentially help alleviate migraine symptoms.
Furthermore, we noted that other antioxidants might also play a role, but vitamin C stood out in its association with reduced migraine severity. Overall, this research reinforces the idea that dietary choices, particularly those rich in vitamin C, could benefit those grappling with migraine headaches and should be closely monitored.
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
7
Vitamin E's mixed effects on headaches
We aimed to understand how vitamin E influences headaches in relation to oxidative stress and calcium levels. Our exploration involved the use of glyceryl trinitrate to induce migraine-like symptoms in experimental models.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
References
- Zhao D, Long X, Wang J. Association between dietary vitamin C intake and migraine in adults: A cross-sectional study of the National Health and Nutrition Examination Survey. J Hum Nutr Diet. 2024;37:1454. doi:10.1111/jhn.13366
- Hajishizari S, Mirzababaei A, Abaj F, Bahrampour N, Moradi S, et al. The association between dietary antioxidant quality score and intensity and frequency of migraine headaches among women: a cross-sectional study. BMC Womens Health. 2024;24:497. doi:10.1186/s12905-024-03260-3
- Visser EJ, Drummond PD, Lee-Visser JLA. Reduction in Migraine and Headache Frequency and Intensity With Combined Antioxidant Prophylaxis (N-acetylcysteine, Vitamin E, and Vitamin C): A Randomized Sham-Controlled Pilot Study. Pain Pract. 2020;20:737. doi:10.1111/papr.12902
- Lauritsen CG, Chua AL, Nahas SJ. Current Treatment Options: Headache Related to Menopause-Diagnosis and Management. Curr Treat Options Neurol. 2018;20:7. doi:10.1007/s11940-018-0492-7
- Bütün A, Nazıroğlu M, Demirci S, Çelik Ö, Uğuz AC. Riboflavin and vitamin E increase brain calcium and antioxidants, and microsomal calcium-ATP-ase values in rat headache models induced by glyceryl trinitrate. J Membr Biol. 2015;248:205. doi:10.1007/s00232-014-9758-5
- Ziaei S, Kazemnejad A, Sedighi A. The effect of vitamin E on the treatment of menstrual migraine. Med Sci Monit. 2009;15:CR16.
- Chayasirisobhon S. Use of a pine bark extract and antioxidant vitamin combination product as therapy for migraine in patients refractory to pharmacologic medication. Headache. 2006;46:788.
