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NOW Supplements BioCell Collagen® Hydrolyzed Type II
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 35 Reviews
8.3
Supplement Facts
Serving Size: 2 Veg Capsules
Serving Per Container: 60
Amount Per Serving
%DV
BioCell Collagen® (Hydrolyzed Chicken Sternal Cartilage Extract) providing
1 g (1,000 mg)
**
Hydrolyzed Type II Collagen
570 mg
**
Chondroitin Sulfate
190 mg
**
Hyaluronic Acid
95 mg
**

Top Medical Research Studies

8
Collagen supplements improve knee pain
The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy: a randomized, double-blind, placebo-controlled study.
Study shows positive initial results
We investigated whether collagen supplements could ease pain and improve quality of life for patients with knee meniscus issues. This randomized, double-blind, placebo-controlled study involved 32 participants, half receiving collagen and half a placebo.

After eight weeks, we noted that those taking collagen reported reduced pain and enhanced quality of life, along with improvements in some physical tests. While the results are promising, more extensive studies are needed to explore long-term benefits and outcomes for different patient groups.
Read More
8
Collagen peptides effectively reduce knee pain
Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides.
Significant improvement in knee pain
We investigated the effects of specific collagen peptides on knee pain in athletes experiencing functional issues. Over 12 weeks, 139 participants took either 5 g of these peptides or a placebo daily.

Participants reported a noticeable reduction in activity-related pain, which was confirmed by physicians.

While resting pain also improved, it wasn't statistically significant. Additionally, those taking collagen needed fewer additional treatments. Overall, collagen peptides appear to be an effective option for managing knee pain during physical activity.
Read More
9
Collagen reduces knee osteoarthritis pain
Oral Administration of Protease-Soluble Chicken Type II Collagen Ameliorates Anterior Cruciate Ligament Transection-Induced Osteoarthritis in Rats.
Strong relevance for knee pain
This study set out to determine if oral collagen supplements could help treat knee pain linked to osteoarthritis caused by ACL injury in rats.

We found that different types of collagen, especially the protease-soluble chicken type II collagen, not only reduced pain sensitivity but also improved cartilage health.

Rats given collagen showed significant improvements compared to those who didn't receive it, leading to better joint function and less inflammation.

Overall, collagen treatment appears beneficial for managing knee pain related to osteoarthritis.
Read More

Most Useful Reviews

9.5
Notable improvements
I recommended this for my mother whose knees pained her excessively, to the point of struggling to walk. Doctors suggested costly knee injections, yet many report them as ineffective. Instead, we opted for collagen, glucosamine, and chondroitin in courses, leading to noticeable improvements. We will continue this regimen.
Read More
9.5
Visible improvements
I’m delighted with this super collagen. Despite its small size, it has impressive benefits, particularly for my knee pain, which has subsided significantly. I noticed improvements in my health with regular use.
Read More
9.5
Significant improvement
Effective! This is a great complex. My mum has finger joint issues and I have knee pain which causes crunching during fitness. We take it in courses for three months, and after three weeks, I felt noticeable improvement. By the end of the course, our issues seemed to vanish. Highly recommended!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
  • All Researches
9
Collagen supplement reduces knee pain
Open, Observational, Single-Arm, Multicenter Study Assessing the Effectiveness of a Dietary Supplement Containing Hydrolyzed Collagen, Chondroitin Sulfate, and Glucosamine for Osteoarthritis Pain Reduction.
Promising for osteoarthritis management
We investigated the effects of a dietary supplement containing hydrolyzed collagen, chondroitin sulfate, glucosamine, turmeric extract, and devil's claw on knee pain and function in osteoarthritis patients.

In a study with 186 participants over six months, they reported a significant decrease in pain and improved joint function. Measures showed noticeable pain relief at both three and six months, as well as enhancements in overall functioning.

Comfortingly, there were no severe side effects noted during the observation period.
Read More
9
Collagen reduces knee osteoarthritis pain
Oral Administration of Protease-Soluble Chicken Type II Collagen Ameliorates Anterior Cruciate Ligament Transection-Induced Osteoarthritis in Rats.
Strong relevance for knee pain
This study set out to determine if oral collagen supplements could help treat knee pain linked to osteoarthritis caused by ACL injury in rats.

We found that different types of collagen, especially the protease-soluble chicken type II collagen, not only reduced pain sensitivity but also improved cartilage health.

Rats given collagen showed significant improvements compared to those who didn't receive it, leading to better joint function and less inflammation.

Overall, collagen treatment appears beneficial for managing knee pain related to osteoarthritis.
Read More
8
Collagen supplements improve knee pain
The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy: a randomized, double-blind, placebo-controlled study.
Study shows positive initial results
We investigated whether collagen supplements could ease pain and improve quality of life for patients with knee meniscus issues. This randomized, double-blind, placebo-controlled study involved 32 participants, half receiving collagen and half a placebo.

After eight weeks, we noted that those taking collagen reported reduced pain and enhanced quality of life, along with improvements in some physical tests. While the results are promising, more extensive studies are needed to explore long-term benefits and outcomes for different patient groups.
Read More
8
Collagen shows promise for knee pain
Effect of supplementation with type 1 and type 3 collagen peptide and type 2 hydrolyzed collagen on osteoarthritis-related pain, quality of life, and physical function: A double-blind, randomized, placebo-controlled study.
High relevance due to credible structure
This clinical study aimed to evaluate how collagen supplements might ease knee pain related to osteoarthritis.

We involved 31 participants in a controlled setting, comparing those taking collagen with a placebo group over eight weeks.

The findings indicated that collagen supplementation led to improvements in pain levels and quality of life. Some aspects of physical function also showed positive changes, highlighting collagen's potential benefits for those suffering from knee issues.
Read More
8
NXT15906F6 helps reduce knee pain
A Blend of and Extracts Alleviates Monosodium Iodoacetate (MIA)-Induced Osteoarthritic Pain and Joint Inflammation in Rats.
Key findings on knee pain treatment.
We conducted a study to see how effective a herbal supplement, NXT15906F6 (also known as TamaFlex), is in reducing knee pain and joint inflammation, specifically in a rat model of osteoarthritis. The rats were divided into groups and received either this supplement or a standard medication called Celecoxib over 28 days.

Post-treatment results revealed that NXT15906F6 significantly decreased joint pain and inflammation, while also improving the overall joint condition. The study showed promising signs by reducing harmful proteins that can cause joint damage. This suggests that NXT15906F6 could be a beneficial option for managing knee pain more effectively.
Read More

User Reviews

USERS' SCORE
Good
Based on 35 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Notable improvements
I recommended this for my mother whose knees pained her excessively, to the point of struggling to walk. Doctors suggested costly knee injections, yet many report them as ineffective. Instead, we opted for collagen, glucosamine, and chondroitin in courses, leading to noticeable improvements. We will continue this regimen.
Read More
9.5
Visible improvements
I’m delighted with this super collagen. Despite its small size, it has impressive benefits, particularly for my knee pain, which has subsided significantly. I noticed improvements in my health with regular use.
9.5
Significant improvement
Effective! This is a great complex. My mum has finger joint issues and I have knee pain which causes crunching during fitness. We take it in courses for three months, and after three weeks, I felt noticeable improvement. By the end of the course, our issues seemed to vanish. Highly recommended!
Read More
9.5
Stopped knee crunching
This product works effectively when combined with chondroprotectors and vitamins. I have found that my knees have stopped crunching and hurting since I started using it.
8.3
Excellent for joints
I took Collagen for my mother because of her knee. It is excellent and has an acceptable taste. The benefits are remarkable.
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