Dietary impact on Hashimoto's inflammationThe Influence of an Anti-Inflammatory Gluten-Free Diet with EPA and DHA on the Involvement of Maresin and Resolvins in Hashimoto's Disease.
Moderate relevance to Hashimoto's treatment
We explored how a gluten-free diet (GFD) enriched with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) might influence thyroid inflammation in women with Hashimoto's thyroiditis (HT). This study included 39 Caucasian female patients with autoimmune HT, focusing on the role of long-chain fatty acids as mediators in the inflammatory process.
Notably, we observed that the introduction of a GFD, complemented by omega-3 fatty acids and an increase in vegetable intake, seemed to help reduce inflammation levels in these patients. Specifically, we saw an increase in anti-inflammatory mediators such as resolvins and maresins. This suggests that while eliminating gluten may not be necessary for everyone with HT, the inclusion of EPA and DHA alongside a healthy diet can provoke positive anti-inflammatory changes.
However, it's essential to point out that we found no significant changes in specific thyroid antibody markers, namely anti-TPO and anti-TG levels, meaning that while the dietary approach showed promise, it didn’t necessarily affect every aspect of Hashimoto's disease. Overall, the results highlight the potential of dietary strategies in managing inflammation related to HT.
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Dietary omega-3s improve inflammationThe Influence of an Anti-Inflammatory Gluten-Free Diet with EPA and DHA on the Involvement of Maresin and Resolvins in Hashimoto's Disease.
Moderate relevance due to design
We explored the role of a gluten-free diet supplemented with docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) in influencing the inflammation associated with Hashimoto’s thyroiditis (HT). Our study focused on 39 Caucasian women diagnosed with autoimmune HT to assess how these dietary changes might affect inflammatory responses.
Through careful analysis of metabolites, we observed that introducing a gluten-free diet with omega-3 fatty acids, including DHA, may help alleviate inflammation related to Hashimoto’s. We noted an increase in anti-inflammatory fatty acid mediators after dietary changes, suggesting potential benefits of such dietary interventions for people with HT.
However, it is important to clarify that while we saw significant changes in inflammatory markers, the specific impact of DHA alone remains unclear. Moreover, our findings did not reveal any improvements in thyroid antibodies. This indicates that while dietary changes can have a positive impact on inflammation, the direct effects of DHA on Hashimoto's may require further investigation.
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