I was researching for a supplement that protects the liver when taking Acetaminophen. I found the following information in an article by Julius Goepp, MD. NAC is a defense against some of today's most deadly public health threats. 1. Acetaminophen toxicity and acute liver failure: the number one cause of acute liver failure in the United States. 2. Influenza: whose victims are primarily aging individualsâ€"three quarters of all flu-related deaths occur in the elderly. 3. Chronic obstructive pulmonary disease: the fourth-leading cause of death in the United States (includes emphysema and chronic bronchitis). 4. Helicobacter pylori: the bacterial culprit behind stomach ulcers, and a potentially lethal pathogen closely linked to malignant gastric cancer, the second most frequent cause of cancer death worldwide. N-ACETYL CYSTEINE'S BROAD-SPECTRUM BENEFITS 1. NAC replenishes levels of the intracellular antioxidant glutathione (GSH), which is often deficient with advancing age and in chronic illness. 2. NAC also regulates expression of scores of genes in the pathways that link oxidative stress to inflammation. 3. These dual effects give NAC a unique role in the prevention and treatment of many common diseases, both acute and chronic. 4. NAC can protect against avian Influenza and more common seasonal flu symptoms. 5. NAC reduces the frequency and duration of attacks of chronic obstructive pulmonary disease (COPD) and may slow the clinical course of idiopathic pulmonary fibrosis (IPF). 6. NAC protects tissues from the effects of exercise-induced oxidative stress, adding value and safety to your workout. 7. NAC improves insulin sensitivity in people with some of the most difficult-to-treat metabolic disorders. 8. NAC blocks cancer development at virtually every step in the process, and through multiple mechanisms, making it an important cancer chemo preventive agent. 9. NAC fights the stomach infection Helicobacter pylori on two fronts, inhibiting the organism's growth while reducing production of inflammatory cytokines that can lead to gastritis and cancer. Though most individuals gain benefits from 600-1,800 mg/day, clinical studies have found that doses of up to 2,000 mg/day are safe and effective. A recent study demonstrated the safety of 2,800 mg/day for 3 months in patients with COPD