Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.9
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Calories
10
 
Total Fat
1.3 g
2%*
Polyunsaturated Fat
1 g
Monounsaturated Fat
<0.5 g
Evening Primrose Oil(Oenothera biennis) (Seed) (Cold-Pressed, Hexane-Free)
1.3 g (1,300 mg)
Gamma Linolenic Acid (GLA)
120 mg

Top Medical Research Studies

7
EPO shows symptom relief potential
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).

Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.

However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.

Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.
Read More
8
EPO shows promise for arthritis
We explored the effects of evening primrose oil (EPO) on rheumatoid arthritis, a condition marked by inflammation and dangerous new blood vessel formation. In our study, we used male albino rats with induced arthritis to see how EPO, alone or combined with common medications like aspirin and celecoxib, could help.

The results were promising, showing that EPO could normalize body weight and reduce harmful levels of specific inflammatory markers. Moreover, it helped decrease inflammation and improve overall joint health. Although combining EPO with other treatments enhanced its effects, we observed that EPO alone provides significant benefits in managing arthritis symptoms.
Read More
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.

However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
Read More

Most Useful Reviews

7.5
Improves arthritis symptoms
54 people found this helpful
This oil is fantastic! It’s rich in gamma-linolenic acid and helps alleviate menstrual and menopausal symptoms, skin issues, arthritis, and improves fertility. I've noticed an improvement in my skin's elasticity and moisture. For best results, it's advised to take the capsules for 12 weeks. Stay healthy!
Read More
9
Relieves arthritis pain
2 people found this helpful
The Evening Primrose Oil from NOW is effective for reducing arthritis pain.
Read More
9
Arthritis symptom relief
1 people found this helpful
Evening primrose oil offers numerous benefits including alleviating rheumatoid arthritis, menopause symptoms, and skin disorders. It's effective in treating various ailments.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
  • All Researches
We examined the impact of evening primrose oil combined with fish oil on patients with rheumatoid arthritis through a 12-week study involving 60 participants. The results showed that both fish oil and the combination with evening primrose oil led to significant improvements in symptoms, like reduced disease activity scores and fewer tender joints.

However, while evening primrose oil contributed positively, the study emphasized the notable benefits of omega-3 fatty acids alone as well. Overall, this suggests a potential pathway for improving arthritis symptoms through these supplements.
Read More
8
EPO shows promise for arthritis
We explored the effects of evening primrose oil (EPO) on rheumatoid arthritis, a condition marked by inflammation and dangerous new blood vessel formation. In our study, we used male albino rats with induced arthritis to see how EPO, alone or combined with common medications like aspirin and celecoxib, could help.

The results were promising, showing that EPO could normalize body weight and reduce harmful levels of specific inflammatory markers. Moreover, it helped decrease inflammation and improve overall joint health. Although combining EPO with other treatments enhanced its effects, we observed that EPO alone provides significant benefits in managing arthritis symptoms.
Read More
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.

However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
Read More
7
EPO shows symptom relief potential
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).

Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.

However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.

Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.
Read More
4
Mild benefits of evening primrose oil
We conducted a six-month double-blind study exploring the effects of evening primrose oil on rheumatoid arthritis.

In total, 40 patients participated, with half receiving evening primrose oil and the other half a placebo.

While we noted a slight improvement in morning stiffness at three months with evening primrose oil, olive oil showed more significant reductions in pain and overall joint issues at the six-month mark.

This suggests that evening primrose oil provides only mild benefits, while olive oil may have important, previously overlooked advantages.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 25 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Improves arthritis symptoms
54 people found this helpful
This oil is fantastic! It’s rich in gamma-linolenic acid and helps alleviate menstrual and menopausal symptoms, skin issues, arthritis, and improves fertility. I've noticed an improvement in my skin's elasticity and moisture. For best results, it's advised to take the capsules for 12 weeks. Stay healthy!
Read More
9
Relieves arthritis pain
2 people found this helpful
The Evening Primrose Oil from NOW is effective for reducing arthritis pain.
Read More
9
Arthritis symptom relief
1 people found this helpful
Evening primrose oil offers numerous benefits including alleviating rheumatoid arthritis, menopause symptoms, and skin disorders. It's effective in treating various ailments.
Read More
9
Eased arthritis pain
1 people found this helpful
A must for women! The oil is rich in gamma-linolenic acid, helping alleviate PMS, menopause symptoms, and conditions like arthritis. My cycle is now regular without notice.
Read More
7.5
Reduced arthritis symptoms
1 people found this helpful
Greta is a great alternative for those with seafood or fish allergies who want the benefits of omegas. It has been quite effective for my arthritis!
Read More

Frequently Asked Questions

7.5
Improves arthritis symptoms
54 people found this helpful
This oil is fantastic! It’s rich in gamma-linolenic acid and helps alleviate menstrual and menopausal symptoms, skin issues, arthritis, and improves fertility. I've noticed an improvement in my skin's elasticity and moisture. For best results, it's advised to take the capsules for 12 weeks. Stay healthy!
7.5
Positive arthritis effects
NOW Foods Primrose quality is excellent. It offers relief from inflammation and aids in arthritis and menopause symptoms. Results are seen after three months. I plan to reorder.
9
Enhanced arthritis mobility
3 people found this helpful
Evening primrose oil has significantly improved my arthritis and mobility. I highly recommend it.
2
Not suitable for arthritis
While evening primrose oil contains beneficial gamma-linolenic acid, it didn't suit me as I experienced spotting during my cycle. Although it has many advantages for treating PMS, menopause, and skin conditions like psoriasis and arthritis, my personal reaction was not positive. If you haven't tried it before, I recommend starting with a smaller dosage to see if it's right for you.
7.5
Reduced arthritis symptoms
1 people found this helpful
Greta is a great alternative for those with seafood or fish allergies who want the benefits of omegas. It has been quite effective for my arthritis!
9
Relieves arthritis pain
2 people found this helpful
The Evening Primrose Oil from NOW is effective for reducing arthritis pain.
7.5
Improved arthritis management
1 people found this helpful
The quality is decent, especially at a discount. Evening primrose oil is renowned for its benefits to women's health and has aided my rheumatoid arthritis and other conditions.
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.

However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
We examined the impact of evening primrose oil combined with fish oil on patients with rheumatoid arthritis through a 12-week study involving 60 participants. The results showed that both fish oil and the combination with evening primrose oil led to significant improvements in symptoms, like reduced disease activity scores and fewer tender joints.

However, while evening primrose oil contributed positively, the study emphasized the notable benefits of omega-3 fatty acids alone as well. Overall, this suggests a potential pathway for improving arthritis symptoms through these supplements.
4
Mild benefits of evening primrose oil
We conducted a six-month double-blind study exploring the effects of evening primrose oil on rheumatoid arthritis.

In total, 40 patients participated, with half receiving evening primrose oil and the other half a placebo.

While we noted a slight improvement in morning stiffness at three months with evening primrose oil, olive oil showed more significant reductions in pain and overall joint issues at the six-month mark.

This suggests that evening primrose oil provides only mild benefits, while olive oil may have important, previously overlooked advantages.
7
EPO shows symptom relief potential
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).

Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.

However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.

Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.

References

  1. Veselinovic M, Vasiljevic D, Vucic V, Arsic A, Petrovic S, et al. Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. Nutrients. 2017;9. doi:10.3390/nu9040325
  2. El-Sayed RM, Moustafa YM, El-Azab MF. Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1. Inflammopharmacology. 2014;22:305. doi:10.1007/s10787-014-0200-5
  3. Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst Rev. 2011. doi:10.1002/14651858.CD002948.pub2
  4. Brzeski M, Madhok R, Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol. 1991;30:370.
  5. Belch JJ, Ansell D, Madhok R, O'Dowd A, Sturrock RD. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. Ann Rheum Dis. 1988;47:96.
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