Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study.
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).
Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.
However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.
Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.
Read More
8
EPO shows promise for arthritis
Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1.
We explored the effects of evening primrose oil (EPO) on rheumatoid arthritis, a condition marked by inflammation and dangerous new blood vessel formation. In our study, we used male albino rats with induced arthritis to see how EPO, alone or combined with common medications like aspirin and celecoxib, could help.
The results were promising, showing that EPO could normalize body weight and reduce harmful levels of specific inflammatory markers. Moreover, it helped decrease inflammation and improve overall joint health. Although combining EPO with other treatments enhanced its effects, we observed that EPO alone provides significant benefits in managing arthritis symptoms.
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.
However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
Read More
Most Useful Reviews
7.5
Improves arthritis symptoms
54 people found this helpful
This oil is fantastic! It’s rich in gamma-linolenic acid and helps alleviate menstrual and menopausal symptoms, skin issues, arthritis, and improves fertility. I've noticed an improvement in my skin's elasticity and moisture. For best results, it's advised to take the capsules for 12 weeks. Stay healthy!
Read More
9
Relieves arthritis pain
2 people found this helpful
The Evening Primrose Oil from NOW is effective for reducing arthritis pain.
Read More
9
Arthritis symptom relief
1 people found this helpful
Evening primrose oil offers numerous benefits including alleviating rheumatoid arthritis, menopause symptoms, and skin disorders. It's effective in treating various ailments.
We examined the impact of evening primrose oil combined with fish oil on patients with rheumatoid arthritis through a 12-week study involving 60 participants. The results showed that both fish oil and the combination with evening primrose oil led to significant improvements in symptoms, like reduced disease activity scores and fewer tender joints.
However, while evening primrose oil contributed positively, the study emphasized the notable benefits of omega-3 fatty acids alone as well. Overall, this suggests a potential pathway for improving arthritis symptoms through these supplements.
Read More
8
EPO shows promise for arthritis
Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1.
We explored the effects of evening primrose oil (EPO) on rheumatoid arthritis, a condition marked by inflammation and dangerous new blood vessel formation. In our study, we used male albino rats with induced arthritis to see how EPO, alone or combined with common medications like aspirin and celecoxib, could help.
The results were promising, showing that EPO could normalize body weight and reduce harmful levels of specific inflammatory markers. Moreover, it helped decrease inflammation and improve overall joint health. Although combining EPO with other treatments enhanced its effects, we observed that EPO alone provides significant benefits in managing arthritis symptoms.
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.
However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
Read More
7
EPO shows symptom relief potential
Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study.
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).
Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.
However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.
Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.
Read More
4
Mild benefits of evening primrose oil
Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs.
We conducted a six-month double-blind study exploring the effects of evening primrose oil on rheumatoid arthritis.
In total, 40 patients participated, with half receiving evening primrose oil and the other half a placebo.
While we noted a slight improvement in morning stiffness at three months with evening primrose oil, olive oil showed more significant reductions in pain and overall joint issues at the six-month mark.
This suggests that evening primrose oil provides only mild benefits, while olive oil may have important, previously overlooked advantages.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
7.5
Improves arthritis symptoms
54 people found this helpful
This oil is fantastic! It’s rich in gamma-linolenic acid and helps alleviate menstrual and menopausal symptoms, skin issues, arthritis, and improves fertility. I've noticed an improvement in my skin's elasticity and moisture. For best results, it's advised to take the capsules for 12 weeks. Stay healthy!
Read More
9
Relieves arthritis pain
2 people found this helpful
The Evening Primrose Oil from NOW is effective for reducing arthritis pain.
Read More
9
Arthritis symptom relief
1 people found this helpful
Evening primrose oil offers numerous benefits including alleviating rheumatoid arthritis, menopause symptoms, and skin disorders. It's effective in treating various ailments.
Read More
9
Eased arthritis pain
1 people found this helpful
A must for women! The oil is rich in gamma-linolenic acid, helping alleviate PMS, menopause symptoms, and conditions like arthritis. My cycle is now regular without notice.
Read More
7.5
Reduced arthritis symptoms
1 people found this helpful
Greta is a great alternative for those with seafood or fish allergies who want the benefits of omegas. It has been quite effective for my arthritis!
Arthritis is a general term that refers to inflammation of the joints, which can lead to pain, stiffness, and swelling. It encompasses over 100 different types, with osteoarthritis and rheumatoid arthritis being the most common. Osteoarthritis, often associated with aging, occurs when the cartilage that cushions the joints wears down over time. In contrast, rheumatoid arthritis is an autoimmune disorder where the body's immune system mistakenly attacks the joints, leading to chronic inflammation and potential disability if left untreated.
Symptoms of arthritis can vary widely depending on the type but typically include joint pain, swelling, reduced range of motion, and sometimes fatigue. Diagnosis usually involves a combination of physical exams, imaging tests, and blood tests. While there is currently no cure for arthritis, various treatments ranging from lifestyle modifications, physical therapy, and medications can help manage symptoms and improve quality of life. For those affected, seeking early diagnosis and intervention is crucial for slowing disease progression and preserving joint function.
Evening Primrose Oil is derived from the seeds of the evening primrose plant (Oenothera biennis), a native North American flowering plant known for its bright yellow blooms that open in the evening. This oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid that plays a crucial role in various bodily functions, including maintaining skin health and regulating inflammation. Due to its high GLA content, evening primrose oil is often used as a dietary supplement to assist with a variety of health concerns, such as symptoms associated with premenstrual syndrome (PMS), menopause, and conditions that involve inflammation like eczema.
In addition to its potential health benefits when taken in supplement form, many users also apply evening primrose oil topically to help improve skin health, reduce dryness, and soothe irritations. While some research supports its benefits, results can vary, and it’s always recommended to consult with a healthcare professional before adding any new supplement to your routine. Overall, evening primrose oil is celebrated for its versatility as both a dietary and topical addition, making it a popular choice among those seeking natural wellness options.
Evening Primrose Oil (EPO) has been studied for its potential benefits in managing arthritis symptoms, primarily due to its high content of gamma-linolenic acid (GLA), an omega-6 fatty acid. Some research suggests that GLA may help reduce inflammation and pain associated with arthritis, particularly rheumatoid arthritis. A few small studies have indicated that EPO can improve overall joint function and reduce stiffness, making it a tempting option for those seeking natural remedies. However, results can vary significantly among individuals, and more extensive, well-designed trials are needed to fully establish its effectiveness.
It's important to note that while some individuals may find relief with EPO, it should not replace conventional medical treatment for arthritis. Always consult with a healthcare professional before starting any new supplement, especially if you are currently on medication or have underlying health issues. They can provide guidance tailored to your specific health needs and help you understand how EPO might fit into your broader treatment plan.
Based on user reviews, individuals taking Evening Primrose Oil for arthritis typically report noticing results after approximately 12 weeks of consistent usage Read Review. This timeframe aligns with comments about needing a sustained intake to achieve optimal benefits, particularly for alleviating joint pain and inflammation associated with arthritis Read Review.
Many users have mentioned experiencing a reduction in symptoms after several weeks of regular intake, suggesting that patience and persistence are key for seeing improvements. Some feedback also highlighted significant gains in mobility and overall health after several months of use Read Review. However, individual responses may vary, so it may be beneficial to monitor one's own experience during the initial weeks of supplementation.
Evening primrose oil (EPO) has garnered attention in the scientific community for its potential benefits in managing arthritis symptoms, particularly for rheumatoid arthritis (RA). Studies, including a systematic review of 22 papers, indicate that EPO may help alleviate pain and improve functionality in RA patients due to its high gamma linolenic acid content [3]. For instance, one study with 60 participants highlighted that EPO, when combined with fish oil, significantly improved symptoms such as disease activity scores and tender joints, although the omega-3 fatty acids were primarily responsible for these benefits [1].
However, not all studies unanimously support EPO's effectiveness. While some results show promising reductions in inflammation and improvement in overall joint health, others have noted only mild benefits compared to other treatments like olive oil [4]. Additionally, a long-term study emphasized that while participants experienced some symptom relief during the initial months, EPO did not alter disease progression, suggesting it should be viewed more as a supportive treatment rather than a cure [5]. Overall, while there is moderate evidence for EPO's role in managing arthritis, further rigorous studies are needed to solidify its place in arthritis treatment regimens.
Users have reported a variety of positive improvements in their symptoms after using Evening Primrose Oil. Many reviewers emphasized its effectiveness for alleviating conditions such as arthritis, menstrual cramps, and menopause symptoms. For instance, several individuals have noted a significant reduction in arthritis pain and improved mobility after sustained use, with one user stating, "Evening primrose oil has significantly improved my arthritis and mobility" Read Review. Others highlighted improvements in skin health, mentioning enhanced elasticity and moisture Read Review.
Some users reported needing to persist with the product for about three months to see tangible results, particularly for inflammatory conditions Read Review. Overall, while many have experienced benefits—ranging from relief in pain to improved hormonal balance—it's essential to recognize that individual experiences can vary widely. As evidenced by one user's experience of spotting during their cycle, it may be helpful for newcomers to start with a smaller dosage to assess their personal response Read Review.
According to user reviews, many individuals have found that combining Evening Primrose Oil with other supplements enhances its effectiveness in managing arthritis symptoms. Users report that this oil, rich in gamma-linolenic acid, can be particularly beneficial when used in conjunction with omega-3 supplements or other anti-inflammatory aids, helping to further alleviate joint pain and inflammation associated with arthritis Read Review. Some suggest that regular intake of Evening Primrose Oil, particularly over three months, yields significant improvements in mobility and overall pain reduction, making it a viable addition to a comprehensive supplement regimen Read Review.
While the oil is generally praised for its effectiveness on its own, users recommend individual experimentation to determine the best combination for their specific needs. This approach allows for tailoring dosages and combinations with other supplements based on personal experiences and results Read Review. Overall, many users advocate for the synergy that can be achieved through a well-rounded supplementation strategy, leading to enhanced management of arthritis symptoms Read Review.
Based on user reviews, the right dosage of Evening Primrose Oil for treating arthritis appears to be around three months of consistent use for optimal results. Many users recommend starting with capsules, noting that they can help alleviate joint pain and improve mobility associated with arthritis, although specific dosage amounts are not universally stated. For instance, one reviewer suggested taking the oil for 12 weeks to see significant improvements (Read Review).
Additionally, some users have experienced benefits from taking the oil without specifying a dosage, indicating that it helped reduce inflammation and arthritis symptoms effectively (Read Review, Read Review). It's also recommended that individuals begin with smaller doses to gauge tolerance, particularly if they have had negative reactions in the past (Read Review). Overall, consistency over a few months is key for realizing the potential benefits of this supplement for arthritis management.
7.5
Improves arthritis symptoms
54 people found this helpful
This oil is fantastic! It’s rich in gamma-linolenic acid and helps alleviate menstrual and menopausal symptoms, skin issues, arthritis, and improves fertility. I've noticed an improvement in my skin's elasticity and moisture. For best results, it's advised to take the capsules for 12 weeks. Stay healthy!
7.5
Positive arthritis effects
NOW Foods Primrose quality is excellent. It offers relief from inflammation and aids in arthritis and menopause symptoms. Results are seen after three months. I plan to reorder.
9
Enhanced arthritis mobility
3 people found this helpful
Evening primrose oil has significantly improved my arthritis and mobility. I highly recommend it.
2
Not suitable for arthritis
While evening primrose oil contains beneficial gamma-linolenic acid, it didn't suit me as I experienced spotting during my cycle. Although it has many advantages for treating PMS, menopause, and skin conditions like psoriasis and arthritis, my personal reaction was not positive. If you haven't tried it before, I recommend starting with a smaller dosage to see if it's right for you.
7.5
Reduced arthritis symptoms
1 people found this helpful
Greta is a great alternative for those with seafood or fish allergies who want the benefits of omegas. It has been quite effective for my arthritis!
9
Relieves arthritis pain
2 people found this helpful
The Evening Primrose Oil from NOW is effective for reducing arthritis pain.
7.5
Improved arthritis management
1 people found this helpful
The quality is decent, especially at a discount. Evening primrose oil is renowned for its benefits to women's health and has aided my rheumatoid arthritis and other conditions.
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.
However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
9
Evening primrose oil shows promise
Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis.
We examined the impact of evening primrose oil combined with fish oil on patients with rheumatoid arthritis through a 12-week study involving 60 participants. The results showed that both fish oil and the combination with evening primrose oil led to significant improvements in symptoms, like reduced disease activity scores and fewer tender joints.
However, while evening primrose oil contributed positively, the study emphasized the notable benefits of omega-3 fatty acids alone as well. Overall, this suggests a potential pathway for improving arthritis symptoms through these supplements.
4
Mild benefits of evening primrose oil
Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs.
We conducted a six-month double-blind study exploring the effects of evening primrose oil on rheumatoid arthritis.
In total, 40 patients participated, with half receiving evening primrose oil and the other half a placebo.
While we noted a slight improvement in morning stiffness at three months with evening primrose oil, olive oil showed more significant reductions in pain and overall joint issues at the six-month mark.
This suggests that evening primrose oil provides only mild benefits, while olive oil may have important, previously overlooked advantages.
7
EPO shows symptom relief potential
Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study.
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).
Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.
However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.
Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.
References
Veselinovic M, Vasiljevic D, Vucic V, Arsic A, Petrovic S, et al. Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. Nutrients. 2017;9. doi:10.3390/nu9040325
El-Sayed RM, Moustafa YM, El-Azab MF. Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1. Inflammopharmacology. 2014;22:305. doi:10.1007/s10787-014-0200-5
Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst Rev. 2011. doi:10.1002/14651858.CD002948.pub2
Brzeski M, Madhok R, Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol. 1991;30:370.
Belch JJ, Ansell D, Madhok R, O'Dowd A, Sturrock RD. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. Ann Rheum Dis. 1988;47:96.