Last update
6/13/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Moderately Good
Based on 28 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1.3 g
2%*
Polyunsaturated Fat
1 g
†
Monounsaturated Fat
<0.5 g
†
Evening Primrose Oil(Oenothera biennis) (Seed) (Cold-Pressed, Hexane-Free)
1.3 g (1,300 mg)
†
Gamma Linolenic Acid (GLA)
120 mg
†
Top Medical Research Studies
8
Evening primrose oil reduces LDL cholesterol
We examined the effects of evening primrose oil, high in gammalinolenic acid, on cholesterol levels in nineteen patients with high cholesterol. This study used a rigorous crossover design where participants received both the evening primrose oil and a placebo safflower oil over 16 weeks.
During the evening primrose oil treatment, we noticed a significant reduction in low-density lipoprotein (LDL) cholesterol levels and apolipoprotein B in patients without hypertriglyceridemia. These findings suggest that evening primrose oil can be beneficial for individuals struggling with high cholesterol.
During the evening primrose oil treatment, we noticed a significant reduction in low-density lipoprotein (LDL) cholesterol levels and apolipoprotein B in patients without hypertriglyceridemia. These findings suggest that evening primrose oil can be beneficial for individuals struggling with high cholesterol.
Read More
8
Gamma-linolenic acid reduces cholesterol
We explored how evening primrose oil (EPO) affects cholesterol levels by comparing its effects with safflower oil and olive oil in male rats on high-cholesterol diets.
Our findings revealed that EPO was more effective at lowering cholesterol than safflower oil, particularly in the initial two weeks. Even when the phytosterol content was equalized, EPO continued to show better results.
This suggests that gamma-linolenic acid in EPO has a notable cholesterol-lowering effect, which may be significant for potential applications in dietary management.
Our findings revealed that EPO was more effective at lowering cholesterol than safflower oil, particularly in the initial two weeks. Even when the phytosterol content was equalized, EPO continued to show better results.
This suggests that gamma-linolenic acid in EPO has a notable cholesterol-lowering effect, which may be significant for potential applications in dietary management.
Read More
4
We investigated the impact of evening primrose oil on cholesterol levels using New Zealand White rabbits. A noteworthy increase in high-density lipoprotein (HDL) cholesterol was observed after four weeks of supplementation, which persisted even two weeks after stopping the oil.
However, overall plasma cholesterol and triglycerides remained unchanged. We saw significant alterations in HDL subfractions, with an increase in HDL2b and HDL3c. These results indicate that n-6 fatty acid supplementation could help prevent atherosclerosis in the long run.
However, overall plasma cholesterol and triglycerides remained unchanged. We saw significant alterations in HDL subfractions, with an increase in HDL2b and HDL3c. These results indicate that n-6 fatty acid supplementation could help prevent atherosclerosis in the long run.
Read More
Most Useful Reviews
7.5
Cycle restoration
15 people found this helpful
I have no complaints about the packaging, and the capsules are easy to take. After three months, I've noticed my cycle has improved, and my hair and nails are growing better. It has also led to a slight drop in my high cholesterol levels, which is encouraging.
Read More
9
Improved skin health
2 people found this helpful
The product quality is remarkable. I take a capsule daily, and I've seen a significant improvement in my skin and hair. Primrose oil aids in inflammation reduction, positively affects blood quality, heart health, and hormonal cycles, thanks to its beneficial composition.
Read More
9
Balancing hormones
1 people found this helpful
Very high-quality evening primrose that helped normalise my hormone imbalance and supported my efforts to conceive.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
- All Researches
8
Evening primrose oil reduces LDL cholesterol
We examined the effects of evening primrose oil, high in gammalinolenic acid, on cholesterol levels in nineteen patients with high cholesterol. This study used a rigorous crossover design where participants received both the evening primrose oil and a placebo safflower oil over 16 weeks.
During the evening primrose oil treatment, we noticed a significant reduction in low-density lipoprotein (LDL) cholesterol levels and apolipoprotein B in patients without hypertriglyceridemia. These findings suggest that evening primrose oil can be beneficial for individuals struggling with high cholesterol.
During the evening primrose oil treatment, we noticed a significant reduction in low-density lipoprotein (LDL) cholesterol levels and apolipoprotein B in patients without hypertriglyceridemia. These findings suggest that evening primrose oil can be beneficial for individuals struggling with high cholesterol.
Read More
8
Gamma-linolenic acid reduces cholesterol
We explored how evening primrose oil (EPO) affects cholesterol levels by comparing its effects with safflower oil and olive oil in male rats on high-cholesterol diets.
Our findings revealed that EPO was more effective at lowering cholesterol than safflower oil, particularly in the initial two weeks. Even when the phytosterol content was equalized, EPO continued to show better results.
This suggests that gamma-linolenic acid in EPO has a notable cholesterol-lowering effect, which may be significant for potential applications in dietary management.
Our findings revealed that EPO was more effective at lowering cholesterol than safflower oil, particularly in the initial two weeks. Even when the phytosterol content was equalized, EPO continued to show better results.
This suggests that gamma-linolenic acid in EPO has a notable cholesterol-lowering effect, which may be significant for potential applications in dietary management.
Read More
4
We investigated the impact of evening primrose oil on cholesterol levels using New Zealand White rabbits. A noteworthy increase in high-density lipoprotein (HDL) cholesterol was observed after four weeks of supplementation, which persisted even two weeks after stopping the oil.
However, overall plasma cholesterol and triglycerides remained unchanged. We saw significant alterations in HDL subfractions, with an increase in HDL2b and HDL3c. These results indicate that n-6 fatty acid supplementation could help prevent atherosclerosis in the long run.
However, overall plasma cholesterol and triglycerides remained unchanged. We saw significant alterations in HDL subfractions, with an increase in HDL2b and HDL3c. These results indicate that n-6 fatty acid supplementation could help prevent atherosclerosis in the long run.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 28 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Cycle restoration
15 people found this helpful
I have no complaints about the packaging, and the capsules are easy to take. After three months, I've noticed my cycle has improved, and my hair and nails are growing better. It has also led to a slight drop in my high cholesterol levels, which is encouraging.
Read More
9
Improved skin health
2 people found this helpful
The product quality is remarkable. I take a capsule daily, and I've seen a significant improvement in my skin and hair. Primrose oil aids in inflammation reduction, positively affects blood quality, heart health, and hormonal cycles, thanks to its beneficial composition.
Read More
9
Balancing hormones
1 people found this helpful
Very high-quality evening primrose that helped normalise my hormone imbalance and supported my efforts to conceive.
Read More
9
Good for symptoms
1 people found this helpful
This product is excellent in terms of price and quantity, odourless, and it effectively lowers cholesterol, making it beneficial for menstrual symptoms.
Read More
9
High cholesterol support
17 people found this helpful
I took this for various women's health issues along with other supplements. Its high omega-6 content is notable for boosting immunity and helps to restore cellular health, also treating high cholesterol. The capsules, though large, are manageable for me.
Read More
Frequently Asked Questions
7.5
Cycle restoration
15 people found this helpful
I have no complaints about the packaging, and the capsules are easy to take. After three months, I've noticed my cycle has improved, and my hair and nails are growing better. It has also led to a slight drop in my high cholesterol levels, which is encouraging.
9
Anti-age benefits
1 people found this helpful
The quality of this ingredient is phenomenal. I've seen noticeable anti-age effects after just a few days. It helps reduce high cholesterol and inflammation while improving heart and hair health.
9
Balances hormones, lowers cholesterol
1 people found this helpful
Great deal! This supplement has a higher concentration than Blackmores, therefore I only need one pill daily to assist with hormone balance and support lowering my high cholesterol.
8
Evening primrose oil reduces LDL cholesterol
We examined the effects of evening primrose oil, high in gammalinolenic acid, on cholesterol levels in nineteen patients with high cholesterol. This study used a rigorous crossover design where participants received both the evening primrose oil and a placebo safflower oil over 16 weeks.
During the evening primrose oil treatment, we noticed a significant reduction in low-density lipoprotein (LDL) cholesterol levels and apolipoprotein B in patients without hypertriglyceridemia. These findings suggest that evening primrose oil can be beneficial for individuals struggling with high cholesterol.
During the evening primrose oil treatment, we noticed a significant reduction in low-density lipoprotein (LDL) cholesterol levels and apolipoprotein B in patients without hypertriglyceridemia. These findings suggest that evening primrose oil can be beneficial for individuals struggling with high cholesterol.
4
We investigated the impact of evening primrose oil on cholesterol levels using New Zealand White rabbits. A noteworthy increase in high-density lipoprotein (HDL) cholesterol was observed after four weeks of supplementation, which persisted even two weeks after stopping the oil.
However, overall plasma cholesterol and triglycerides remained unchanged. We saw significant alterations in HDL subfractions, with an increase in HDL2b and HDL3c. These results indicate that n-6 fatty acid supplementation could help prevent atherosclerosis in the long run.
However, overall plasma cholesterol and triglycerides remained unchanged. We saw significant alterations in HDL subfractions, with an increase in HDL2b and HDL3c. These results indicate that n-6 fatty acid supplementation could help prevent atherosclerosis in the long run.
8
Gamma-linolenic acid reduces cholesterol
We explored how evening primrose oil (EPO) affects cholesterol levels by comparing its effects with safflower oil and olive oil in male rats on high-cholesterol diets.
Our findings revealed that EPO was more effective at lowering cholesterol than safflower oil, particularly in the initial two weeks. Even when the phytosterol content was equalized, EPO continued to show better results.
This suggests that gamma-linolenic acid in EPO has a notable cholesterol-lowering effect, which may be significant for potential applications in dietary management.
Our findings revealed that EPO was more effective at lowering cholesterol than safflower oil, particularly in the initial two weeks. Even when the phytosterol content was equalized, EPO continued to show better results.
This suggests that gamma-linolenic acid in EPO has a notable cholesterol-lowering effect, which may be significant for potential applications in dietary management.
References
- Fragoso YD, Skinner ER. The effect of gammalinolenic acid on the subfractions of plasma high density lipoprotein of the rabbit. Biochem Pharmacol. 1992;44:1085. PubMed
- Ishikawa T, Fujiyama Y, Igarashi O, Morino M, Tada N, et al. Effects of gammalinolenic acid on plasma lipoproteins and apolipoproteins. Atherosclerosis. 1989;75:95. PubMed
- Sugano M, Ide T, Ishida T, Yoshida K. Hypocholesterolemic effect of gamma-linolenic acid as evening primrose oil in rats. Ann Nutr Metab. 1986;30:289. PubMed
