Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 12 Reviews
8.2
Supplement Facts
Serving Size: 1 Fish Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
<5 mg
1%
Vitamin D3 (as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%
Fish Oil Concentrate
1.2 g (1,200 mg)
†
Omega-3 Fatty Acids:
Eicosapentaenoic Acid (EPA)
600 mg
†
Docosahexaenoic Acid (DHA)
300 mg
†
Top Medical Research Studies
8
We discovered that a diet enriched with omega-3 fatty acids can effectively reduce symptoms of allergic conjunctivitis (AC) in mice. This reduction occurred without influencing the typical immune responses usually associated with allergies. Instead, omega-3s worked by changing the lipid molecules linked to inflammation.
Notably, these fatty acids completely suppressed itching near the eyes and significantly decreased the presence of eosinophils, cells commonly involved in allergic reactions. However, total serum IgE levels and T2 cytokine expression remained unchanged, suggesting that omega-3s tackle AC symptoms in a unique way.
Notably, these fatty acids completely suppressed itching near the eyes and significantly decreased the presence of eosinophils, cells commonly involved in allergic reactions. However, total serum IgE levels and T2 cytokine expression remained unchanged, suggesting that omega-3s tackle AC symptoms in a unique way.
Read More
9.5
Maternal omega-3 reduces allergy risks
We conducted a comprehensive meta-analysis to explore how omega-3 supplementation affects food allergy risks in children, focusing on whether maternal intake during pregnancy or childhood supplementation is more effective.
Our findings revealed that mothers who took omega-3 during pregnancy and lactation significantly lowered the chances of their infants developing allergies to eggs and peanuts.
However, omega-3 consumption later in childhood did not show similar benefits in allergy prevention. This emphasizes the critical timing of supplementation in allergy risk management.
Our findings revealed that mothers who took omega-3 during pregnancy and lactation significantly lowered the chances of their infants developing allergies to eggs and peanuts.
However, omega-3 consumption later in childhood did not show similar benefits in allergy prevention. This emphasizes the critical timing of supplementation in allergy risk management.
Read More
8
Omega-3 postbiotics reduce allergies
We examined how certain omega-3 postbiotics might address allergic reactions, specifically in mice.
Through our study, we found that a metabolite called t10,c15-18:2, derived from omega-3 fatty acids, effectively reduced skin inflammation associated with contact allergies.
It was particularly successful in easing symptoms like swelling and edema, distinguishing its effectiveness from another compound. This action seemed connected to its ability to inhibit a molecule that increases blood vessel activity, offering potential for therapeutic use in managing allergic conditions.
Through our study, we found that a metabolite called t10,c15-18:2, derived from omega-3 fatty acids, effectively reduced skin inflammation associated with contact allergies.
It was particularly successful in easing symptoms like swelling and edema, distinguishing its effectiveness from another compound. This action seemed connected to its ability to inhibit a molecule that increases blood vessel activity, offering potential for therapeutic use in managing allergic conditions.
Read More
Most Useful Reviews
9
Value for quality
This Omega is good, offering solid value for money. I'm satisfied with it, and it did not cause any allergies.
Read More
9
No side effects
The product combines Vitamin D and fish oil in one capsule, improving absorption and eliminating the need for additional capsules. It did not cause any side effects or allergies.
Read More
9
Gentle on skin
Excellent size for adults. The product is beneficial and has a wonderful composition. It is not refined and doesn't cause allergies, providing high moisture and gentleness.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9.5
Maternal omega-3 reduces allergy risks
We conducted a comprehensive meta-analysis to explore how omega-3 supplementation affects food allergy risks in children, focusing on whether maternal intake during pregnancy or childhood supplementation is more effective.
Our findings revealed that mothers who took omega-3 during pregnancy and lactation significantly lowered the chances of their infants developing allergies to eggs and peanuts.
However, omega-3 consumption later in childhood did not show similar benefits in allergy prevention. This emphasizes the critical timing of supplementation in allergy risk management.
Our findings revealed that mothers who took omega-3 during pregnancy and lactation significantly lowered the chances of their infants developing allergies to eggs and peanuts.
However, omega-3 consumption later in childhood did not show similar benefits in allergy prevention. This emphasizes the critical timing of supplementation in allergy risk management.
Read More
8
Omega-3 postbiotics reduce allergies
We examined how certain omega-3 postbiotics might address allergic reactions, specifically in mice.
Through our study, we found that a metabolite called t10,c15-18:2, derived from omega-3 fatty acids, effectively reduced skin inflammation associated with contact allergies.
It was particularly successful in easing symptoms like swelling and edema, distinguishing its effectiveness from another compound. This action seemed connected to its ability to inhibit a molecule that increases blood vessel activity, offering potential for therapeutic use in managing allergic conditions.
Through our study, we found that a metabolite called t10,c15-18:2, derived from omega-3 fatty acids, effectively reduced skin inflammation associated with contact allergies.
It was particularly successful in easing symptoms like swelling and edema, distinguishing its effectiveness from another compound. This action seemed connected to its ability to inhibit a molecule that increases blood vessel activity, offering potential for therapeutic use in managing allergic conditions.
Read More
8
We explored the link between maternal fatty acids and allergies in children during their first 2 years of life, focusing on a group of 573 mother-infant pairs in China. By analyzing the fatty acid levels in mothers, we found that higher levels of total polyunsaturated fatty acids (PUFA), particularly arachidonic acid and omega-3, were linked to a lower risk of allergies in their children.
Interestingly, the relationship was even stronger in children whose mothers had allergies. Our findings suggest that maternal intake of specific omega-3 fatty acids might play a beneficial role in reducing allergy risks for their offspring.
Interestingly, the relationship was even stronger in children whose mothers had allergies. Our findings suggest that maternal intake of specific omega-3 fatty acids might play a beneficial role in reducing allergy risks for their offspring.
Read More
8
We examined how long-chain polyunsaturated fatty acids (LCPUFAs) like DHA and EPA influence the immune system and allergies in infants. Research shows that mothers who intake n-3 LCPUFAs during pregnancy may reduce their baby's chances of developing allergies and asthma. Infants fed formula with these fatty acids had immune responses similar to breastfed babies, leading to a lower risk of allergic diseases. Overall, our findings suggest that LCPUFAs are important for immune system development and may help prevent allergic conditions in early life.
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8
We explored how a mother’s omega-3 fatty acid intake affects the allergic responses of their pups. By focusing on the diets high in omega-3s, we investigated how these fatty acids influence breast milk composition and ultimately reduce the chances of allergic conditions in infants.
Our findings indicate that omega-3 fatty acids lead to beneficial changes in immune responses in infant mice, specifically reducing skin allergies. However, it's important to note that while these results are encouraging, further studies are needed to confirm this effect in humans.
Our findings indicate that omega-3 fatty acids lead to beneficial changes in immune responses in infant mice, specifically reducing skin allergies. However, it's important to note that while these results are encouraging, further studies are needed to confirm this effect in humans.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Value for quality
This Omega is good, offering solid value for money. I'm satisfied with it, and it did not cause any allergies.
Read More
9
No side effects
The product combines Vitamin D and fish oil in one capsule, improving absorption and eliminating the need for additional capsules. It did not cause any side effects or allergies.
Read More
9
Gentle on skin
Excellent size for adults. The product is beneficial and has a wonderful composition. It is not refined and doesn't cause allergies, providing high moisture and gentleness.
Read More
9
Improved mental clarity
One of the best omega supplements for me, worth every penny. My husband and I took it, and we noticed improved skin condition and mental clarity. The capsules are large but easy to swallow, and they do not cause allergies.
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9
Skin and hair enhancement
This is a favourite supplement for our family. It doesn’t cause allergies and is gentle on the liver and stomach. It’s essential to take with food and isn't easily found in local pharmacies. I’ve noticed an improvement in skin complexion and smoother skin. With vitamin D added to omega, it’s perfect for our long winters. I will definitely reorder.
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Frequently Asked Questions
7.5
Improved skin condition
Easy to drink and long-lasting, this product does not trigger allergies. I consistently purchase it, and after using it, my facial skin improved significantly; the rashes are less bothersome, and my nails are better. My parents also take it and are pleased with the results.
0
Caused itchy allergies
It caused me allergies and itching in my body. I don’t like it at all. I felt no benefit from it, as it triggered allergies.
7.5
Relieved severe allergies
I bought this for a friend for treating severe allergies. The results were surprising. The "ultra omega-3-D" combines Omega-3 and vitamin D, both of which are typically low in St. Petersburg residents. I highly recommend it unless contraindicated by a doctor.
9
Improved mental clarity
One of the best omega supplements for me, worth every penny. My husband and I took it, and we noticed improved skin condition and mental clarity. The capsules are large but easy to swallow, and they do not cause allergies.
9
Skin and hair enhancement
This is a favourite supplement for our family. It doesn’t cause allergies and is gentle on the liver and stomach. It’s essential to take with food and isn't easily found in local pharmacies. I’ve noticed an improvement in skin complexion and smoother skin. With vitamin D added to omega, it’s perfect for our long winters. I will definitely reorder.
7.5
Strengthened immunity noted
This Omega is one of the best; it normalises the nervous system and enhances immunity. It significantly reduces the risk of allergies. It's essential for skin health and can be used regularly to prevent hair brittleness.
9
No side effects
The product combines Vitamin D and fish oil in one capsule, improving absorption and eliminating the need for additional capsules. It did not cause any side effects or allergies.
9.5
Maternal omega-3 reduces allergy risks
We conducted a comprehensive meta-analysis to explore how omega-3 supplementation affects food allergy risks in children, focusing on whether maternal intake during pregnancy or childhood supplementation is more effective.
Our findings revealed that mothers who took omega-3 during pregnancy and lactation significantly lowered the chances of their infants developing allergies to eggs and peanuts.
However, omega-3 consumption later in childhood did not show similar benefits in allergy prevention. This emphasizes the critical timing of supplementation in allergy risk management.
Our findings revealed that mothers who took omega-3 during pregnancy and lactation significantly lowered the chances of their infants developing allergies to eggs and peanuts.
However, omega-3 consumption later in childhood did not show similar benefits in allergy prevention. This emphasizes the critical timing of supplementation in allergy risk management.
8
We explored the link between maternal fatty acids and allergies in children during their first 2 years of life, focusing on a group of 573 mother-infant pairs in China. By analyzing the fatty acid levels in mothers, we found that higher levels of total polyunsaturated fatty acids (PUFA), particularly arachidonic acid and omega-3, were linked to a lower risk of allergies in their children.
Interestingly, the relationship was even stronger in children whose mothers had allergies. Our findings suggest that maternal intake of specific omega-3 fatty acids might play a beneficial role in reducing allergy risks for their offspring.
Interestingly, the relationship was even stronger in children whose mothers had allergies. Our findings suggest that maternal intake of specific omega-3 fatty acids might play a beneficial role in reducing allergy risks for their offspring.
8
We discovered that a diet enriched with omega-3 fatty acids can effectively reduce symptoms of allergic conjunctivitis (AC) in mice. This reduction occurred without influencing the typical immune responses usually associated with allergies. Instead, omega-3s worked by changing the lipid molecules linked to inflammation.
Notably, these fatty acids completely suppressed itching near the eyes and significantly decreased the presence of eosinophils, cells commonly involved in allergic reactions. However, total serum IgE levels and T2 cytokine expression remained unchanged, suggesting that omega-3s tackle AC symptoms in a unique way.
Notably, these fatty acids completely suppressed itching near the eyes and significantly decreased the presence of eosinophils, cells commonly involved in allergic reactions. However, total serum IgE levels and T2 cytokine expression remained unchanged, suggesting that omega-3s tackle AC symptoms in a unique way.
7
Omega-3 supplementation's weak effectiveness
We conducted a systematic review and meta-analysis to explore whether omega-3 fatty acids taken during pregnancy affect allergic outcomes in children.
While our findings indicate that starting omega-3 supplementation during pregnancy may reduce the risk of sensitization to foods like egg and peanut, the overall evidence is somewhat limited.
This stems from the small number of studies available and concerns regarding their reliability, making it hard to draw definitive conclusions about omega-3's effects on allergies.
While our findings indicate that starting omega-3 supplementation during pregnancy may reduce the risk of sensitization to foods like egg and peanut, the overall evidence is somewhat limited.
This stems from the small number of studies available and concerns regarding their reliability, making it hard to draw definitive conclusions about omega-3's effects on allergies.
References
- Saika A, Nagatake T, Kishino S, Kitamura N, Honda T, et al. The omega-3 postbiotic -10--15-octadecadienoic acid attenuates contact hypersensitivity in mice through downregulation of vascular endothelial growth factor A. Front Cell Infect Microbiol. 2024;14:1355679. 10.3389/fcimb.2024.1355679
- Tsuji S, Adachi Y, Tsuchida A, Hamazaki K, Matsumura K, et al. Association of allergies in children younger than 3 years with levels of maternal intake of n-3 polyunsaturated fatty acids or fish during pregnancy: A nationwide birth cohort study, the Japan Environment and Children's Study. Allergol Int. 2024;73:282. 10.1016/j.alit.2023.12.004
- Huynh LBP, Nguyen NN, Fan HY, Huang SY, Huang CH, et al. Maternal Omega-3 Supplementation During Pregnancy, but Not Childhood Supplementation, Reduces the Risk of Food Allergy Diseases in Offspring. J Allergy Clin Immunol Pract. 2023;11:2862. 10.1016/j.jaip.2023.06.005
- Peng S, Du Z, He Y, Zhao F, Chen Y, et al. Association of Maternal Erythrocyte PUFA during Pregnancy with Offspring Allergy in the Chinese Population. Nutrients. 2022;14. 10.3390/nu14112312
- Adjibade M, Davisse-Paturet C, Bernard JY, Adel-Patient K, Divaret-Chauveau A, et al. Enrichment of infant formula with long-chain polyunsaturated fatty acids and risk of infection and allergy in the nationwide ELFE birth cohort. Allergy. 2022;77:1522. 10.1111/all.15137
- Miles EA, Childs CE, Calder PC. Long-Chain Polyunsaturated Fatty Acids (LCPUFAs) and the Developing Immune System: A Narrative Review. Nutrients. 2021;13. 10.3390/nu13010247
- Hirata SI, Nagatake T, Sawane K, Hosomi K, Honda T, et al. Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL-expressing plasmacytoid dendritic cells in mice. Allergy. 2020;75:1939. 10.1111/all.14217
- Huhmann R, Mueller RS. A cream containing omega-3-fatty acids, humectants and emollients as an aid in the treatment of equine Culicoides hypersensitivity. Vet Dermatol. 2019;30:155. 10.1111/vde.12728
- Vahdaninia M, Mackenzie H, Dean T, Helps S. ω-3 LCPUFA supplementation during pregnancy and risk of allergic outcomes or sensitization in offspring: A systematic review and meta-analysis. Ann Allergy Asthma Immunol. 2019;122:302. 10.1016/j.anai.2018.12.008
- Hirakata T, Lee HC, Ohba M, Saeki K, Okuno T, et al. Dietary ω-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating T2 immune responses. FASEB J. 2019;33:3392. 10.1096/fj.201801805R
- Clausen M, Jonasson K, Keil T, Beyer K, Sigurdardottir ST. Fish oil in infancy protects against food allergy in Iceland-Results from a birth cohort study. Allergy. 2018;73:1305. 10.1111/all.13385
- Hansen S, Strøm M, Maslova E, Dahl R, Hoffmann HJ, et al. Fish oil supplementation during pregnancy and allergic respiratory disease in the adult offspring. J Allergy Clin Immunol. 2017;139:104. 10.1016/j.jaci.2016.02.042
- Best KP, Sullivan T, Palmer D, Gold M, Kennedy DJ, et al. Prenatal Fish Oil Supplementation and Allergy: 6-Year Follow-up of a Randomized Controlled Trial. Pediatrics. 2016;137. 10.1542/peds.2015-4443
- Willemsen LEM. Dietary n-3 long chain polyunsaturated fatty acids in allergy prevention and asthma treatment. Eur J Pharmacol. 2016;785:174. 10.1016/j.ejphar.2016.03.062
- Warstedt K, Furuhjelm C, Fälth-Magnusson K, Fagerås M, Duchén K. High levels of omega-3 fatty acids in milk from omega-3 fatty acid-supplemented mothers are related to less immunoglobulin E-associated disease in infancy. Acta Paediatr. 2016;105:1337. 10.1111/apa.13395
- Ahmed N, Barrow CJ, Suphioglu C. Exploring the Effects of Omega-3 and Omega-6 Fatty Acids on Allergy Using a HEK-Blue Cell Line. Int J Mol Sci. 2016;17:220. 10.3390/ijms17020220
