Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 11 Reviews
8.6
Supplement Facts
Serving Size: 1 Fish Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%**
Cholesterol
<5 mg
1%
Vitamin D3 (as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%
Fish Oil Concentrate
1.2 g (1,200 mg)
Omega-3 Fatty Acids:
 
 
Eicosapentaenoic Acid (EPA)
600 mg
Docosahexaenoic Acid (DHA)
300 mg

Top Medical Research Studies

9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
Read More
8
Omega-3s reduce headache frequency
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.

Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.

Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
Read More
8
Omega-3 fish oil reduces headaches
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.

While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.

This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.
Read More

Most Useful Reviews

10
Headache was cured
My mother's headache has vanished. I consistently buy this for her. Although I've been taking it for years due to high cholesterol, I was concerned about occasional headaches. After taking this, her headaches were effectively cured.
Read More
10
Quick effect
After being treated with hormone diprospan, I suffered severe headaches. I started taking Omega and, after two weeks, the headaches disappeared along with the rise in pressure and heartbeat. I'm astonished by the quick effects!
Read More
9
Headaches stopped bothering
Great! After using it, headaches stopped bothering me, and I no longer feel the pressure fluctuations as much. Overall, this product is excellent for health, and I’m very pleased with my purchase.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
  • All Researches
9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
Read More
9
Omega-3 diet improves headaches
We examined how adjusting omega-3 and omega-6 fatty acids influences chronic headaches and overall well-being. In a randomized trial with 67 participants suffering from severe headaches, those who increased omega-3 intake while decreasing omega-6 saw significant improvements in their headaches and reductions in psychological distress.

Over 12 weeks, participants in this dietary intervention reported better mental and physical health, which also helped decrease the number of headache days. Overall, this approach not only targets headache relief but also enhances quality of life.
Read More
8
Omega-3s reduce headache frequency
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.

Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.

Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
Read More
8
Omega-3 fish oil reduces headaches
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.

While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.

This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.
Read More
8
Omega-3 reduces migraine frequency
We explored the effectiveness of omega-3 fatty acids in preventing chronic migraine attacks through a well-structured double-blind study. Sixty patients diagnosed with chronic migraines were split into two groups: one received omega-3 alongside amitriptyline, while the other got a placebo.

After 60 days, we observed that 66.7% of the omega-3 group reported more than an 80% reduction in headache days, compared to only 33.3% in the control group. This shows promise for omega-3 as a migraine preventive, though further study is needed to solidify these findings.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Headache was cured
My mother's headache has vanished. I consistently buy this for her. Although I've been taking it for years due to high cholesterol, I was concerned about occasional headaches. After taking this, her headaches were effectively cured.
Read More
10
Quick effect
After being treated with hormone diprospan, I suffered severe headaches. I started taking Omega and, after two weeks, the headaches disappeared along with the rise in pressure and heartbeat. I'm astonished by the quick effects!
Read More
9
Headaches stopped bothering
Great! After using it, headaches stopped bothering me, and I no longer feel the pressure fluctuations as much. Overall, this product is excellent for health, and I’m very pleased with my purchase.
Read More
9
Headaches disappeared quickly
I took one capsule of this Omega daily. The quality is impressive! I noticed the benefits right away; headaches disappeared, and my hair, legs, and skin visibly improved. Although I dislike taking Omega due to the fishy aftertaste, I know it's one of my most beneficial supplements. Plus, it comes in convenient packaging.
Read More
9
Constant use helps
Now Foods are trustworthy and affordable. I bought this Omega 3 as it includes vitamin D, and my headache disappeared after starting it. I take it steadily.
Read More

Frequently Asked Questions

10
Quick effect
After being treated with hormone diprospan, I suffered severe headaches. I started taking Omega and, after two weeks, the headaches disappeared along with the rise in pressure and heartbeat. I'm astonished by the quick effects!
9
Constant use helps
Now Foods are trustworthy and affordable. I bought this Omega 3 as it includes vitamin D, and my headache disappeared after starting it. I take it steadily.
7.5
Weather dependence disappears
Excellent dosage! This product is remarkably effective. I've been using it for 2 months, taking one capsule daily. During the autumn-spring period, I used to suffer from headaches; however, since starting omega, I feel much better. My headaches have largely subsided, allowing me to enjoy my day more without the burden of discomfort.
10
Headache was cured
My mother's headache has vanished. I consistently buy this for her. Although I've been taking it for years due to high cholesterol, I was concerned about occasional headaches. After taking this, her headaches were effectively cured.
9
Headaches stopped bothering
Great! After using it, headaches stopped bothering me, and I no longer feel the pressure fluctuations as much. Overall, this product is excellent for health, and I’m very pleased with my purchase.
9
Weakness disappeared
Excellent! I purchased it for myself and have no regrets. My mood has seen significant improvement, and I no longer experience weakness or headaches. These vitamins serve as a fantastic supplement for women.
7.5
Headaches decreased
This product gives me super strength! I've been taking this omega along with magnesium for over a month, and I've noticed several things: improved sleep quality, decreased headaches (which I constantly experienced due to vertebral displacement), increased stamina, and calmer demeanour. Additionally, my hair has become thicker. Now, the whole family is taking omega; I highly recommend it!
7.5
Effective fish oil
When I have a headache, swallowing fish oil is very effective. I usually take four pills at a time. If I feel relief, I take another four, but mix them with cheaper fish oil.
7
EPA supplementation may reduce migraines
We conducted a randomized, placebo-controlled trial to explore the effects of daily 2000 mg of eicosapentaenoic acid (EPA) on chronic migraines. Over 8 weeks, participants recorded their headache symptoms, with some taking EPA and others receiving a placebo.

Our findings suggest that EPA may significantly reduce the frequency of migraine attacks and improve overall quality of life for chronic migraine sufferers. However, we believe that more research is needed for a clearer understanding of its benefits and dosage.
7
Fish oil shows promise for migraines
We investigated the effectiveness of fish oil supplementation for managing headache symptoms and improving blood lipid levels in migraine patients.

Participants were given either 1g of fish oil or a soybean oil placebo for 12 weeks.

At the end of the study, those taking fish oil reported notable improvements in the frequency, duration, and intensity of their migraine attacks, along with healthier blood lipid profiles.

This suggests fish oil could be a helpful addition to traditional migraine treatments.
8
Omega-3 diet improves headache relief
We explored how modifying our diet to increase omega-3 fatty acids while decreasing omega-6 can impact headache pain. In a study involving 55 chronic headache patients, we found that this dietary approach significantly boosted beneficial omega-3-derived compounds in the bloodstream and reduced harmful omega-6 derivatives.

These changes were closely linked to notable improvements in headache intensity and psychological well-being. Ultimately, our findings suggest that adjusting our intake of these fatty acids may offer a valuable method for alleviating chronic headaches and improving overall mental health.
This cross-sectional study explored whether eating more long-chain omega-3 fatty acids could help reduce headaches in the U.S. population.

We analyzed data from over 12,000 adults, looking at their reported headaches and dietary intake of omega-3s like EPA and DHA.

Our findings showed that higher intake of these omega-3 fats was linked to a lower chance of experiencing severe headaches or migraines, especially among non-Mexican Hispanics. This suggests that omega-3 fatty acids could play a role in headache prevention.
9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
8
Omega-3 fish oil reduces headaches
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.

While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.

This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.

References

  1. Yeh EL, Yang CP, Lin SW, Wang HF. Feasibility of Fish Oil Supplementation on Headache Symptoms and Blood Lipids in Migraine Patients. Brain Behav. 2024;14:e70149. 10.1002/brb3.70149
  2. Mohammadnezhad G, Assarzadegan F, Koosha M, Esmaily H. Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial. Headache. 2025;65:153. 10.1111/head.14808
  3. Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. 10.1016/j.bbi.2024.03.019
  4. Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions. J Pain. 2023;24:478. 10.1016/j.jpain.2022.10.008
  5. Faurot KR, Cole WR, MacIntosh BA, Dunlap M, Moore CB, et al. Targeted dietary interventions to reduce pain in persistent post-traumatic headache among service members: Protocol for a randomized, controlled parallel-group trial. Contemp Clin Trials. 2022;119:106851. 10.1016/j.cct.2022.106851
  6. Ramsden CE, Zamora D, Faurot KR, MacIntosh B, Horowitz M, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. 10.1136/bmj.n1448
  7. Honarvar NM, Soveid N, Abdolahi M, Djalali M, Hatami M, et al. Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano- Curcumin on Migraine Patients from Cellular to Clinical Insight: A Randomized, Double-Blind and Placebo-Controlled Trial. Endocr Metab Immune Disord Drug Targets. 2021;21:365. 10.2174/1871530320666200729144430
  8. Abdolahi M, Jafarieh A, Sarraf P, Sedighiyan M, Yousefi A, et al. The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms. Endocr Metab Immune Disord Drug Targets. 2019;19:874. 10.2174/1871530319666190212170140
  9. Sanders AE, Shaikh SR, Slade GD. Long-chain omega-3 fatty acids and headache in the U.S. population. Prostaglandins Leukot Essent Fatty Acids. 2018;135:47. 10.1016/j.plefa.2018.06.008
  10. Mann JD, Faurot KR, MacIntosh B, Palsson OS, Suchindran CM, et al. A sixteen-week three-armed, randomized, controlled trial investigating clinical and biochemical effects of targeted alterations in dietary linoleic acid and n-3 EPA+DHA in adults with episodic migraine: Study protocol. Prostaglandins Leukot Essent Fatty Acids. 2018;128:41. 10.1016/j.plefa.2017.11.002
  11. Shen T, Xing G, Zhu J, Zhang S, Cai Y, et al. Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol. Lipids Health Dis. 2017;16:253. 10.1186/s12944-017-0617-0
  12. Soveyd N, Abdolahi M, Djalali M, Hatami M, Tafakhori A, et al. The Combined Effects of ω -3 Fatty Acids and Nano-Curcumin Supplementation on Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression and Serum Levels in Migraine Patients. CNS Neurol Disord Drug Targets. 2018;16:1120. 10.2174/1871527317666171213154749
  13. Abdolahi M, Tafakhori A, Togha M, Okhovat AA, Siassi F, et al. The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients. Immunogenetics. 2017;69:371. 10.1007/s00251-017-0992-8
  14. Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS, et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21:219. 10.1080/1028415X.2016.1266133
  15. Ramsden CE, Zamora D, Makriyannis A, Wood JT, Mann JD, et al. Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress. J Pain. 2015;16:707. 10.1016/j.jpain.2015.04.007
  16. Ramsden CE, Faurot KR, Zamora D, Palsson OS, MacIntosh BA, et al. Targeted alterations in dietary n-3 and n-6 fatty acids improve life functioning and reduce psychological distress among patients with chronic headache: a secondary analysis of a randomized trial. Pain. 2015;156:587. 10.1097/01.j.pain.0000460348.84965.47
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