Last update
3/14/2026
Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Medium or Average
Based on 8 Reviews
6.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Selenium (elemental) (from 20 mg L-Selenomethionine)
100 mcg
182%
📅 Last updated:

Top Medical Research Studies

8
Selenium shows promise for migraines
We explored the effects of selenium supplementation in a double-blinded trial involving 72 patients with migraines. Over 12 weeks, participants received either selenium or a placebo. We observed that those taking selenium experienced reduced headache frequency and severity.

Additionally, selenium improved antioxidant levels and lowered oxidative stress markers. However, it appears that many other factors related to migraine symptoms did not see significant changes. While this research shows promise, further studies are necessary to confirm these findings.
Read More
7
Higher selenium may reduce migraines
We examined how dietary selenium affects the occurrence of migraines, especially looking at age differences. Analyzing data from nearly 10,000 adults in the NHANES survey, we found that higher selenium intake is linked to fewer migraines.

This beneficial effect seems particularly significant for adults aged 20 to 50, where increasing selenium to about 101.9 µg/day appears to help prevent migraines. However, the relationship is complex and influenced by age, highlighting the importance of adequate selenium-rich foods for this age group.
Read More
7
Sodium selenite shows symptom improvement
We explored how sodium selenite affects symptoms in patients with brain tumors. This study included 32 patients who experienced increased intracranial pressure after previous treatments.

Notably, 76% of participants reported significant improvements in their symptoms, including headaches, while 24% experienced slight improvements.

Treatments also positively impacted blood cell counts and enhanced the effects of oxygen therapy. Overall, sodium selenite could be a promising part of supportive care for brain tumor patients experiencing multiple symptoms.
Read More

Most Useful Reviews

0
Severe headache caused
7 people found this helpful
Unfortunately, I experienced a severe headache after taking this. After five days, I found a black spot inside the tablet.
Read More
9
Headache completely faded
1 people found this helpful
I've started feeling better since beginning selenium, which I take with vitamin D and C. My mood has lifted, and my headache has completely faded away.
Read More
9
Frequent headaches ceased
The product has excellent composition and fast delivery. While I take it daily with other supplements, I initially struggled with frequent headaches and fatigue. After just ten days of use, I've noticed a significant energy boost, my headaches have ceased, and my mood has improved greatly.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
  • All Researches
8
Selenium shows promise for migraines
We explored the effects of selenium supplementation in a double-blinded trial involving 72 patients with migraines. Over 12 weeks, participants received either selenium or a placebo. We observed that those taking selenium experienced reduced headache frequency and severity.

Additionally, selenium improved antioxidant levels and lowered oxidative stress markers. However, it appears that many other factors related to migraine symptoms did not see significant changes. While this research shows promise, further studies are necessary to confirm these findings.
Read More
7
Higher selenium may reduce migraines
We examined how dietary selenium affects the occurrence of migraines, especially looking at age differences. Analyzing data from nearly 10,000 adults in the NHANES survey, we found that higher selenium intake is linked to fewer migraines.

This beneficial effect seems particularly significant for adults aged 20 to 50, where increasing selenium to about 101.9 µg/day appears to help prevent migraines. However, the relationship is complex and influenced by age, highlighting the importance of adequate selenium-rich foods for this age group.
Read More
7
Sodium selenite shows symptom improvement
We explored how sodium selenite affects symptoms in patients with brain tumors. This study included 32 patients who experienced increased intracranial pressure after previous treatments.

Notably, 76% of participants reported significant improvements in their symptoms, including headaches, while 24% experienced slight improvements.

Treatments also positively impacted blood cell counts and enhanced the effects of oxygen therapy. Overall, sodium selenite could be a promising part of supportive care for brain tumor patients experiencing multiple symptoms.
Read More

User Reviews

USERS' SCORE
Medium or Average
Based on 8 Reviews
6.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
0
Severe headache caused
7 people found this helpful
Unfortunately, I experienced a severe headache after taking this. After five days, I found a black spot inside the tablet.
Read More
9
Headache completely faded
1 people found this helpful
I've started feeling better since beginning selenium, which I take with vitamin D and C. My mood has lifted, and my headache has completely faded away.
Read More
9
Frequent headaches ceased
The product has excellent composition and fast delivery. While I take it daily with other supplements, I initially struggled with frequent headaches and fatigue. After just ten days of use, I've noticed a significant energy boost, my headaches have ceased, and my mood has improved greatly.
Read More
0
Severe headache experienced
I experienced a severe headache from this product, and I'm unsure of the cause. I ceased using it and suggest consulting a doctor prior to use.
Read More
7.5
Significant health improvement
After my doctor prescribed selenium among other supplements for chronic fatigue and headaches, I noticed a significant health improvement. Although I can't pinpoint which treatment helped the most, selenium has notably contributed to my wellbeing.
Read More

Frequently Asked Questions

9
Frequent headaches ceased
The product has excellent composition and fast delivery. While I take it daily with other supplements, I initially struggled with frequent headaches and fatigue. After just ten days of use, I've noticed a significant energy boost, my headaches have ceased, and my mood has improved greatly.
9
Headache completely faded
1 people found this helpful
I've started feeling better since beginning selenium, which I take with vitamin D and C. My mood has lifted, and my headache has completely faded away.
0
Severe headache experienced
I experienced a severe headache from this product, and I'm unsure of the cause. I ceased using it and suggest consulting a doctor prior to use.
7
Higher selenium may reduce migraines
We examined how dietary selenium affects the occurrence of migraines, especially looking at age differences. Analyzing data from nearly 10,000 adults in the NHANES survey, we found that higher selenium intake is linked to fewer migraines.

This beneficial effect seems particularly significant for adults aged 20 to 50, where increasing selenium to about 101.9 µg/day appears to help prevent migraines. However, the relationship is complex and influenced by age, highlighting the importance of adequate selenium-rich foods for this age group.
8
Selenium shows promise for migraines
We explored the effects of selenium supplementation in a double-blinded trial involving 72 patients with migraines. Over 12 weeks, participants received either selenium or a placebo. We observed that those taking selenium experienced reduced headache frequency and severity.

Additionally, selenium improved antioxidant levels and lowered oxidative stress markers. However, it appears that many other factors related to migraine symptoms did not see significant changes. While this research shows promise, further studies are necessary to confirm these findings.

References

  1. Yu X, Wu L, Zheng H, Wu W, Tian S. Interaction between dietary selenium intake and age on severe headache or migraine in the United States: a population-based study. Front Nutr. 2025;12:1537151. 10.3389/fnut.2025.1537151
  2. Balali A, Sadeghi O, Khorvash F, Rouhani MH, Askari G. The effect of selenium supplementation on oxidative stress, clinical and physiological symptoms in patients with migraine: a double-blinded randomized clinical trial. Front Nutr. 2024;11:1369373. 10.3389/fnut.2024.1369373
  3. Pakdaman A. Symptomatic treatment of brain tumor patients with sodium selenite, oxygen, and other supportive measures. Biol Trace Elem Res. 1998;62:1. PubMed
Data last updated:
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