Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.9
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Selenium (elemental) (from 20 mg L-Selenomethionine)
100 mcg
182%
Top Medical Research Studies
8
Selenium nanoparticles inhibit tuberculosis growth
We assessed the potential of selenium nanoparticles in inhibiting the growth of Mycobacterium tuberculosis, a major global health threat due to rising drug resistance. Our study showed that these nanoparticles can potentially disrupt the bacteria's cell envelope, indicating a novel strategy for treatment. However, despite some promising results, further research is needed to fully establish their effectiveness and practical application in tuberculosis management.
Read More
9
We conducted a controlled study to see how selenium and other micronutrients might help prevent tuberculosis (TB) in people living with HIV in Botswana. Our trial included 878 HIV-positive participants who were not yet on antiretroviral treatment.
We found that supplementing with selenium, either alone or alongside multivitamins, significantly reduced the risk of developing TB compared to those taking a placebo. However, multivitamins on their own did not have the same protective effect.
These findings suggest that selenium supplementation could be an important strategy in tackling TB in HIV-infected individuals, particularly where malnutrition is an issue.
We found that supplementing with selenium, either alone or alongside multivitamins, significantly reduced the risk of developing TB compared to those taking a placebo. However, multivitamins on their own did not have the same protective effect.
These findings suggest that selenium supplementation could be an important strategy in tackling TB in HIV-infected individuals, particularly where malnutrition is an issue.
Read More
8
Selenium inhibits tuberculosis growth
We explored the connection between selenium levels and Mycobacterium tuberculosis (MTB) in patients with pulmonary tuberculosis (PTB). Our study found that patients had lower selenium levels compared to healthy individuals, which impacted their treatment outcomes.
Using methylseleninic acid (MSeA), a selenium donor, we observed its ability to block the growth of MTB in macrophages. This works through important pathways involving autophagy, led by a protein called c-Jun.
Overall, our findings suggest that selenium may be a valuable avenue for improving treatment strategies in PTB.
Using methylseleninic acid (MSeA), a selenium donor, we observed its ability to block the growth of MTB in macrophages. This works through important pathways involving autophagy, led by a protein called c-Jun.
Overall, our findings suggest that selenium may be a valuable avenue for improving treatment strategies in PTB.
Read More
Most Useful Reviews
9
High-quality supplement
Selenium aids in preventing poisoning, heart disease, and reducing stroke risks. It helps fight flu and tuberculosis, decreasing mortality rates among HIV patients. The thyroid gland's antioxidant enzyme activity relies on selenium, which is also vital for hormone regulation in body tissues. This supplement is highly effective and of top quality, addressing essential mineral deficiencies.
Read More
7.5
Fights tuberculosis effectively
A supplement is necessary; selenium is crucial for regulating metabolism and brain function, as well as for preventing various diseases. The daily selenium requirement for both men and women ranges from 15 to 70 μg, depending on age and other factors. Selenium aids in preventing poisoning, heart disease, and blood vessel issues, and it lowers the risk of stroke and Alzheimer's. Supplements containing selenium are beneficial in combating flu and tuberculosis, and they may decrease mortality rates among those diagnosed with HIV.
Read More
7.5
Reduces disease risks
Selenium helps prevent poisoning, cardiovascular diseases, and lowers the risk of strokes and Alzheimer's. Supplements with selenium are shown to assist in fighting flu and tuberculosis, also contributing to reduced mortality rates among those with HIV.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.9
- All Researches
9
We looked into how selenium nanoparticles (SeNPs) could enhance immunity against tuberculosis, particularly through their use as adjuvants in vaccines. By combining SeNPs with the AH antigen, we found that these nanoparticles significantly improved the immune response in mice. The results showed increased levels of protective antibodies and a higher activation of memory T cells in the lungs.
SeNPs helped to reduce infection loads and inflammatory lesions while boosting mucosal immunity, indicating their potential for developing effective tuberculosis vaccines. This study highlights the need for further exploration of SeNPs in vaccine formulations for both animals and potentially humans.
SeNPs helped to reduce infection loads and inflammatory lesions while boosting mucosal immunity, indicating their potential for developing effective tuberculosis vaccines. This study highlights the need for further exploration of SeNPs in vaccine formulations for both animals and potentially humans.
Read More
9
We conducted a controlled study to see how selenium and other micronutrients might help prevent tuberculosis (TB) in people living with HIV in Botswana. Our trial included 878 HIV-positive participants who were not yet on antiretroviral treatment.
We found that supplementing with selenium, either alone or alongside multivitamins, significantly reduced the risk of developing TB compared to those taking a placebo. However, multivitamins on their own did not have the same protective effect.
These findings suggest that selenium supplementation could be an important strategy in tackling TB in HIV-infected individuals, particularly where malnutrition is an issue.
We found that supplementing with selenium, either alone or alongside multivitamins, significantly reduced the risk of developing TB compared to those taking a placebo. However, multivitamins on their own did not have the same protective effect.
These findings suggest that selenium supplementation could be an important strategy in tackling TB in HIV-infected individuals, particularly where malnutrition is an issue.
Read More
9
We conducted a randomized study with 72 patients suffering from prostate tuberculosis to explore how to safeguard their fertility. One group of men received standard tuberculosis treatment alongside a therapy that included dietary supplements with zinc and selenium, while another group only received the standard treatment.
Our findings revealed that the additional therapy made a significant difference. Men who received the spermatoprotective treatment saw marked improvements in sperm count and mobility compared to those who did not.
Therefore, incorporating selenium and other supplements could play an important role in preserving fertility for these patients.
Our findings revealed that the additional therapy made a significant difference. Men who received the spermatoprotective treatment saw marked improvements in sperm count and mobility compared to those who did not.
Therefore, incorporating selenium and other supplements could play an important role in preserving fertility for these patients.
Read More
8
Selenium nanoparticles inhibit tuberculosis growth
We assessed the potential of selenium nanoparticles in inhibiting the growth of Mycobacterium tuberculosis, a major global health threat due to rising drug resistance. Our study showed that these nanoparticles can potentially disrupt the bacteria's cell envelope, indicating a novel strategy for treatment. However, despite some promising results, further research is needed to fully establish their effectiveness and practical application in tuberculosis management.
Read More
8
This study examined how trace elements, specifically zinc and selenium, might influence latent tuberculosis infection (LTBI). Using data from over 6000 participants, researchers found that higher serum levels of zinc were linked to a lower risk of LTBI, while selenium showed no significant impact. Results suggest that maintaining adequate zinc levels is crucial, especially for certain demographics. Overall, we observed that while selenium's role is unclear, ensuring proper trace element balance can potentially aid in TB prevention efforts.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
High-quality supplement
Selenium aids in preventing poisoning, heart disease, and reducing stroke risks. It helps fight flu and tuberculosis, decreasing mortality rates among HIV patients. The thyroid gland's antioxidant enzyme activity relies on selenium, which is also vital for hormone regulation in body tissues. This supplement is highly effective and of top quality, addressing essential mineral deficiencies.
Read More
7.5
Fights tuberculosis effectively
A supplement is necessary; selenium is crucial for regulating metabolism and brain function, as well as for preventing various diseases. The daily selenium requirement for both men and women ranges from 15 to 70 μg, depending on age and other factors. Selenium aids in preventing poisoning, heart disease, and blood vessel issues, and it lowers the risk of stroke and Alzheimer's. Supplements containing selenium are beneficial in combating flu and tuberculosis, and they may decrease mortality rates among those diagnosed with HIV.
Read More
7.5
Reduces disease risks
Selenium helps prevent poisoning, cardiovascular diseases, and lowers the risk of strokes and Alzheimer's. Supplements with selenium are shown to assist in fighting flu and tuberculosis, also contributing to reduced mortality rates among those with HIV.
Read More
6
Boosts immune response
SELENIUM is an essential mineral with potent antioxidant properties. It plays a vital role in protecting cells from free radical damage, enhances antibody production to combat cancer, improves hair and nail health, aids in vitamin E absorption, and regulates metabolic processes. It is also crucial for thyroid function and supports liver health. High selenium levels can enhance the immune systems of individuals facing HIV, flu, tuberculosis, and hepatitis C, whilst helping to maintain heart health and combat chronic diseases.
Read More
Frequently Asked Questions
7.5
Reduces disease risks
Selenium helps prevent poisoning, cardiovascular diseases, and lowers the risk of strokes and Alzheimer's. Supplements with selenium are shown to assist in fighting flu and tuberculosis, also contributing to reduced mortality rates among those with HIV.
6
Boosts immune response
SELENIUM is an essential mineral with potent antioxidant properties. It plays a vital role in protecting cells from free radical damage, enhances antibody production to combat cancer, improves hair and nail health, aids in vitamin E absorption, and regulates metabolic processes. It is also crucial for thyroid function and supports liver health. High selenium levels can enhance the immune systems of individuals facing HIV, flu, tuberculosis, and hepatitis C, whilst helping to maintain heart health and combat chronic diseases.
7.5
Fights tuberculosis effectively
A supplement is necessary; selenium is crucial for regulating metabolism and brain function, as well as for preventing various diseases. The daily selenium requirement for both men and women ranges from 15 to 70 μg, depending on age and other factors. Selenium aids in preventing poisoning, heart disease, and blood vessel issues, and it lowers the risk of stroke and Alzheimer's. Supplements containing selenium are beneficial in combating flu and tuberculosis, and they may decrease mortality rates among those diagnosed with HIV.
9
High-quality supplement
Selenium aids in preventing poisoning, heart disease, and reducing stroke risks. It helps fight flu and tuberculosis, decreasing mortality rates among HIV patients. The thyroid gland's antioxidant enzyme activity relies on selenium, which is also vital for hormone regulation in body tissues. This supplement is highly effective and of top quality, addressing essential mineral deficiencies.
References
- Ge X, Liang Z, Li K, Dong Y, Wang Y, et al. Selenium nanoparticles enhance mucosal immunity against Mycobacterium bovis infection. Int Immunopharmacol. 2024;137:112384. 10.1016/j.intimp.2024.112384
- Parveen S, Sur T, Sarkar S, Roy R. Antagonist Impact of Selenium-Based Nanoparticles Against Mycobacterium tuberculosis. Appl Biochem Biotechnol. 2023;195:3606. 10.1007/s12010-023-04315-1
- Zhao R, Miao W, Li B. The Relation Between Trace Elements and Latent Tuberculosis Infection: a Study Based on National Health and Nutritional Examination Survey 2011-2012. Biol Trace Elem Res. 2023;201:1080. 10.1007/s12011-022-03240-4
- Chen W, Liu Z, Zheng Y, Wei B, Shi J, et al. Selenium donor restricts the intracellular growth of Mycobacterium tuberculosis through the induction of c-Jun-mediated both canonical autophagy and LC3-associated phagocytosis of alveolar macrophages. Microb Pathog. 2021;161:105269. 10.1016/j.micpath.2021.105269
- Ribeiro RCB, de Marins DB, Di Leo I, da Silva Gomes L, de Moraes MG, et al. Anti-tubercular profile of new selenium-menadione conjugates against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain and multidrug-resistant clinical isolates. Eur J Med Chem. 2021;209:112859. 10.1016/j.ejmech.2020.112859
- Nizi MG, Desantis J, Nakatani Y, Massari S, Mazzarella MA, et al. Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors. Eur J Med Chem. 2020;201:112420. 10.1016/j.ejmech.2020.112420
- Pi J, Shen L, Yang E, Shen H, Huang D, et al. Macrophage-Targeted Isoniazid-Selenium Nanoparticles Promote Antimicrobial Immunity and Synergize Bactericidal Destruction of Tuberculosis Bacilli. Angew Chem Int Ed Engl. 2020;59:3226. 10.1002/anie.201912122
- Hussain MI, Ahmed W, Nasir M, Mushtaq MH, Sheikh AA, et al. Immune modulatory and anti-oxidative effect of selenium against pulmonary tuberculosis. Pak J Pharm Sci. 2019;32:779.
- Feleke BE, Feleke TE, Mekonnen D, Beyene MB. Micronutrient levels of tuberculosis patients during the intensive phase, a prospective cohort study. Clin Nutr ESPEN. 2019;31:56. 10.1016/j.clnesp.2019.03.001
- Campa A, Baum MK, Bussmann H, Martinez SS, Farahani M, et al. The effect of micronutrient supplementation on active TB incidence early in HIV infection in Botswana. Nutr Diet Suppl. 2017;2017:37. 10.2147/NDS.S123545
- Thanna S, Goins CM, Knudson SE, Slayden RA, Ronning DR, et al. Thermal and Photoinduced Copper-Promoted C-Se Bond Formation: Synthesis of 2-Alkyl-1,2-benzisoselenazol-3(2H)-ones and Evaluation against Mycobacterium tuberculosis. J Org Chem. 2017;82:3844. 10.1021/acs.joc.7b00440
- Kulchavenya EV, Osadchii AV. [The role of pathogenetic therapy in preserving ejaculate fertility in patients with tuberculosis of prostate]. Urologiia. 2016.
