Iron (elemental) (from 180 mg Ferrous Bisglycinate)(Ferrochel™)
36 mg
200%
Top Medical Research Studies
9
Magnetic stent-grafts improve healing
Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model.
We explored how magnetizable stent-grafts can improve healing in carotid artery pseudoaneurysms by investigating their ability to capture blood outgrowth endothelial cells.
In a porcine model, we compared magnetic stent-grafts with standard non-magnetic ones. The results showed that the magnetic stent-grafts not only occluded all nine pseudoaneurysms but also achieved better cell capture and endothelial growth.
Essentially, the magnetic properties enhanced the healing process, leading to less thrombosis compared to non-magnetic counterparts. This innovative approach could reduce complications associated with these medical devices.
Read More
9
ESA and iron enhance surgery outcomes
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
Read More
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
Read More
Most Useful Reviews
9
Positive improvement
6 people found this helpful
For a while, I struggled with severe anaemia, receiving blood-thinning injections twice a week, and taking agents to increase my blood. Recently, I experienced dizziness and noticed my lower eyelids turning white, prompting me to start this medicine. After three weeks, my eyelid colour improved to red, which I believe indicates a significant effect.
Read More
9
Visible improvement
1 people found this helpful
I didn’t feel any effects from heme iron supplements, so I switched to this one. My eyelids were previously white, but they have since returned to a healthier colour, and a recent blood test confirmed my Hb is within the normal range. I plan to continue using this product!
Read More
0
Ineffective results
33 people found this helpful
I would like to share my experience with this iron supplement for my iron deficiency anaemia. After improving my levels with domestic drugs, I tried this supplement to boost my ferritin but was shocked to see almost no progress after three months. Despite positive reviews, it seems ineffective; I cannot recommend it.
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
Read More
9
Magnetic stent-grafts improve healing
Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model.
We explored how magnetizable stent-grafts can improve healing in carotid artery pseudoaneurysms by investigating their ability to capture blood outgrowth endothelial cells.
In a porcine model, we compared magnetic stent-grafts with standard non-magnetic ones. The results showed that the magnetic stent-grafts not only occluded all nine pseudoaneurysms but also achieved better cell capture and endothelial growth.
Essentially, the magnetic properties enhanced the healing process, leading to less thrombosis compared to non-magnetic counterparts. This innovative approach could reduce complications associated with these medical devices.
Read More
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 7 Reviews
6.4
All Reviews
Positive Reviews
Negative Reviews
9
Positive improvement
6 people found this helpful
For a while, I struggled with severe anaemia, receiving blood-thinning injections twice a week, and taking agents to increase my blood. Recently, I experienced dizziness and noticed my lower eyelids turning white, prompting me to start this medicine. After three weeks, my eyelid colour improved to red, which I believe indicates a significant effect.
Read More
9
Visible improvement
1 people found this helpful
I didn’t feel any effects from heme iron supplements, so I switched to this one. My eyelids were previously white, but they have since returned to a healthier colour, and a recent blood test confirmed my Hb is within the normal range. I plan to continue using this product!
Read More
0
Ineffective results
33 people found this helpful
I would like to share my experience with this iron supplement for my iron deficiency anaemia. After improving my levels with domestic drugs, I tried this supplement to boost my ferritin but was shocked to see almost no progress after three months. Despite positive reviews, it seems ineffective; I cannot recommend it.
Read More
7.5
Flow control
4 people found this helpful
My periods used to be extremely heavy. This supplement has really helped slow the flow. Before taking iron, my menstrual blood resembled water, but now it is thicker and flows more slowly.
Read More
0
No level increase
1 people found this helpful
I did not notice any increase in my iron levels, even after taking two capsules alongside vitamin C. I check my blood monthly and can confirm this supplement has not worked for me. I am now trying ferrous sulfate again.
A blood clot is a mass of blood that changes from a liquid to a gel, effectively forming a plug that can stop bleeding. This natural process, known as coagulation, is critical for preventing excessive blood loss when you sustain an injury. Blood clots can occur in various areas of the body, typically at the site of a wound, but they can also form within blood vessels without an obvious injury, which may lead to serious health complications.
While blood clots are essential for healing, they can pose significant health risks if they form inappropriately. For example, a deep vein thrombosis (DVT) occurs when a clot forms in a deep vein, usually in the legs, and can travel to the lungs, causing a life-threatening condition called a pulmonary embolism. Risk factors for blood clots include prolonged immobility, certain medical conditions, and the use of specific medications, among others. It’s important to recognize the symptoms of abnormal clotting, such as swelling, pain, and redness in the affected area, and seek medical attention if they occur.
Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.
In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.
Based on user reviews, the time it takes to see results from this supplement can vary significantly among individuals. Some users report noticeable improvements within three weeks. For instance, one user observed a color change in their eyelids from white to red, suggesting an improvement in blood health after just three weeks of use Read Review. Another user confirmed through a blood test that their hemoglobin levels returned to normal, further supporting the potential for a relatively quick response Read Review.
Conversely, other users experienced no significant changes after longer periods of use. One user indicated no progress after three months of taking the supplement Read Review, while another mentioned an absence of results despite consistent monthly tracking Read Review. This highlights the importance of individual variability in response times to the supplement. Ultimately, you may want to allow for a timeframe of at least a few weeks to a few months to assess the effectiveness based on your personal experience.
The scientific support for specific supplements targeting blood clots, particularly in cases of deep vein thrombosis (DVT) or post-operative complications, appears to be limited and somewhat ambiguous. One study explored a case of a woman with DVT associated with May-Thurner Syndrome, where iron supplementation was included during treatment. However, the independent effectiveness of iron on resolving blood clots was found to be unclear, as other treatments were also involved, making it difficult to gauge the supplement's direct impact on thrombus resolution [1].
In another investigation focused on surgical patients dealing with anemia, the use of erythropoietin-stimulating agents (ESAs) showed notable reductions in the risk of post-operative blood clots, particularly when combined with intravenous iron. While the study suggested that the combination might enhance patient outcomes, the role of iron supplement alone in preventing or treating blood clots remains inconclusive [2]. Overall, while certain supplements may play supportive roles in broader treatment regimens, there is no clear, definitive research backing any specific supplement as a standalone treatment for blood clots.
Based on user reviews, many individuals have reported notable improvements in their symptoms after using this iron supplement, particularly regarding iron deficiency anaemia. Several users mentioned that their eyelids transitioned from a pale white to a healthier red color, indicating enhanced blood health. For instance, one user saw this change within just three weeks of starting the supplement, suggesting a quick response Read Review. Another user confirmed improvements with a blood test, where their hemoglobin returned to normal levels, reinforcing the positive claims surrounding the product's effectiveness Read Review.
Additionally, users noted improvements in menstrual flow, with one individual experiencing a significant reduction in heaviness, transforming their previously watery blood into a thicker flow Read Review. However, it’s important to mention that individual responses vary widely; some users reported no changes even after prolonged use, while another experienced no increases in iron levels despite diligent monitoring Read ReviewRead Review. Overall, while many users enjoyed significant benefits, results may differ from person to person.
Based on user reviews, combining this iron supplement with vitamin C has yielded mixed results for users aiming to improve their iron levels. One user noted that they did not see any increase in iron levels after taking the supplement with vitamin C for an extended period while monitoring their blood monthly Read Review. Conversely, another individual reported that consistent use of iron during their menstrual cycle led to a significant improvement in their hemoglobin and ferritin levels Read Review.
While some users experienced notable benefits from the supplement alone, such as improved eyelid color and confirmed normal hemoglobin levels, others expressed dissatisfaction with their results despite adhering to their regimen diligently Read ReviewRead Review. The variance in these experiences underscores the importance of tailoring supplementation and consulting a healthcare professional for optimal outcomes.
Based on user reviews, the appropriate dosage for iron in treating blood clotting issues correlates with personal experiences rather than strict recommendations. One user reported notable improvements in their hemoglobin and ferritin levels after taking 1-3 iron tablets regularly for seven days during their menstrual cycle, noting a rise in hemoglobin from 120 to 135 (Read Review). This suggests that a concentrated and consistent intake may be beneficial for some individuals.
However, experiences vary significantly, as another user highlighted a lack of effectiveness even when taking the supplement alongside vitamin C, opting to revert to ferrous sulfate instead (Read Review). Additionally, one user mentioned no observable increase in their iron levels, leading them to inquire about doubling their dosage (Read Review). Ultimately, while some users found success with specific dosages, results appear to depend greatly on individual circumstances, emphasizing the importance of monitoring and consulting healthcare professionals for tailored advice.
9
Positive improvement
6 people found this helpful
For a while, I struggled with severe anaemia, receiving blood-thinning injections twice a week, and taking agents to increase my blood. Recently, I experienced dizziness and noticed my lower eyelids turning white, prompting me to start this medicine. After three weeks, my eyelid colour improved to red, which I believe indicates a significant effect.
9
Visible improvement
1 people found this helpful
I didn’t feel any effects from heme iron supplements, so I switched to this one. My eyelids were previously white, but they have since returned to a healthier colour, and a recent blood test confirmed my Hb is within the normal range. I plan to continue using this product!
0
Ineffective results
33 people found this helpful
I would like to share my experience with this iron supplement for my iron deficiency anaemia. After improving my levels with domestic drugs, I tried this supplement to boost my ferritin but was shocked to see almost no progress after three months. Despite positive reviews, it seems ineffective; I cannot recommend it.
0
No level increase
1 people found this helpful
I did not notice any increase in my iron levels, even after taking two capsules alongside vitamin C. I check my blood monthly and can confirm this supplement has not worked for me. I am now trying ferrous sulfate again.
7.5
Flow control
4 people found this helpful
My periods used to be extremely heavy. This supplement has really helped slow the flow. Before taking iron, my menstrual blood resembled water, but now it is thicker and flows more slowly.
7.5
Boosted haemoglobin
1 people found this helpful
I take iron regularly during my cycle, which has made a substantial difference. After three months of taking 1-3 tablets for seven days, my haemoglobin increased from 120 to 135, and my ferritin levels returned to normal. I recommend this to others experiencing blood loss.
0
No absorption improvement
This supplement hasn’t helped increase my iron absorption. I contacted NOW about potentially doubling the dosage, but I have yet to receive a response. I find their customer service lacking and my iron levels unchanged.
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
9
ESA and iron enhance surgery outcomes
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
References
Basu R, Reddy M, Kaabneh A, Mohamedelamin Khidir Ahmed A, Bamne S. May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women. Cureus. 2024;16:e75621. 10.7759/cureus.75621
Choi UE, Nicholson RC, Frank SM, Cha S, Cho BC, et al. Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia. Vox Sang. 2024;119:1174. 10.1111/vox.13729
Oliver AA, Carlson KD, Price C, Banaskiewicz K, Benike A, et al. Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model. Acta Biomater. 2025. 10.1016/j.actbio.2025.03.040