We conducted a study exploring whether iron deficiency might influence the development of coeliac disease through a method called Mendelian randomization. By analyzing genetic data from nearly 337,000 individuals, we discovered a link between lower iron levels and a higher risk of coeliac disease.
The findings suggest that maintaining good iron status could be vital in preventing this condition. However, while our results are promising, they do not establish a definitive cause-and-effect relationship.
Read More
4
Iron supplementation not significantly beneficial
Iron deficiency without anemia in children with newly diagnosed celiac disease: 1-year follow-up of ferritin levels, with and without iron supplementation.
We examined the effectiveness of iron supplementation in children with newly diagnosed celiac disease who have iron deficiency. Our study reviewed the ferritin levels of these kids on a gluten-free diet over a year.
Interestingly, we found that both those taking iron and those not taking it showed significant increases in ferritin levels. However, there was no marked difference in the outcomes between the two groups. Most importantly, children who adhered to a gluten-free diet tended to normalize their ferritin levels without needing iron supplements.
Read More
9.5
Iron treatment benefits in celiac disease
Anemia Etiology and the Response to a Gluten-Free Diet in Untreated Patients With Celiac Disease: A 2-Year Follow-Up.
We explored how iron deficiency and anemia affect individuals diagnosed with celiac disease (CeD) and the role of a gluten-free diet (GFD) in treating these issues. In a study of 572 patients, about 25% had anemia at the time of diagnosis, with iron deficiency being a major cause.
Interestingly, nearly 90% of those with anemia saw their hemoglobin levels return to normal after two years on a GFD. This suggests a positive response to dietary changes, helping many restore their health through improved nutrition.
Read More
Most Useful Reviews
9
Effective iron supplement
1 people found this helpful
Ferrochel iron bisglycinate has effectively corrected my iron deficiency related to celiac disease, utilising a dual absorption mechanism. Its bioavailability approaches 90-100%, being 2.6 times safer than ferrous sulfate. I found that two doses in one capsule quickly raised my iron levels. Monitoring ferritin, instead of serum iron, is crucial in detecting anaemia. If you struggle with morning fatigue despite normal haemoglobin levels, checking ferritin will reveal much about your health. An equivalent from Russian pharmacies is Sideral forte, but it's considerably pricier.
Read More
9
Cost-effective iron solution
I purchased NOW Foods Iron Double Strength (36 mg, 90 Veggie Caps) and have noticed improvements in my energy levels within a couple of weeks. The vegetarian capsules are gentle on the stomach and do not cause the common side effects of other iron forms. They are free from allergens, and their long-term use is a great value for money, making them ideal for maintaining normal iron levels and enhancing overall health.
Read More
6
Improved haemoglobin levels
1 people found this helpful
This iron supplement helped me increase my haemoglobin from 108 to 132. Additionally, I incorporated vitamin C and B vitamins, while eliminating sugar, gluten, and dairy from my diet.
We explored how iron deficiency and anemia affect individuals diagnosed with celiac disease (CeD) and the role of a gluten-free diet (GFD) in treating these issues. In a study of 572 patients, about 25% had anemia at the time of diagnosis, with iron deficiency being a major cause.
Interestingly, nearly 90% of those with anemia saw their hemoglobin levels return to normal after two years on a GFD. This suggests a positive response to dietary changes, helping many restore their health through improved nutrition.
Read More
9
Atypical celiac disease presented effectively
Diagnostic dilemma of celiac disease presenting with weight loss and secondary amenorrhea: A case report.
We reported a case of a 30-year-old woman who experienced unexplained weight loss, menstrual irregularities, and severe fatigue, leading to a diagnosis of celiac disease (CD). Interestingly, her symptoms were atypical and lacked the usual gastrointestinal signs.
Through a strict gluten-free diet and supplementation of essential vitamins and minerals like iron and folate, she exhibited remarkable improvement within three months, regaining hemoglobin levels and restoring her menstrual cycle.
This case emphasizes the importance of recognizing atypical presentations of CD, as they can often lead to under-diagnosis of this complex condition.
Read More
8
Study on ultra-short coeliac disease
New entity of adult ultra-short coeliac disease: the first international cohort and case-control study.
We conducted an international study involving 137 patients with ultra-short coeliac disease (USCD) to understand its characteristics compared to conventional coeliac disease.
Our findings revealed that USCD patients were younger and had overall similar symptoms, but experienced less iron deficiency. Despite these differences, both groups showed similar improvements in health after starting a gluten-free diet.
This research highlights the importance of careful diagnostic sampling in the duodenal bulb for better identification of this unique condition.
Read More
8
Iron status affects coeliac disease risk
Investigating the role of iron status in the development of coeliac disease: a Mendelian randomisation study.
We conducted a study exploring whether iron deficiency might influence the development of coeliac disease through a method called Mendelian randomization. By analyzing genetic data from nearly 337,000 individuals, we discovered a link between lower iron levels and a higher risk of coeliac disease.
The findings suggest that maintaining good iron status could be vital in preventing this condition. However, while our results are promising, they do not establish a definitive cause-and-effect relationship.
Read More
4
Long-term anemia remains in Celiac
Persistence of anemia in patients with Celiac disease despite a gluten free diet: a retrospective study.
We examined the prevalence of anemia in patients with Celiac Disease (CD) before and after they started a gluten-free diet (GFD). Through our cross-sectional study, we gathered blood data from 311 participants over the years, revealing that 17.8% of adults and 4.4% of children still struggled with anemia even after several years on the GFD.
While adults showed some improvement over time, with anemia rates dropping from 24% to 17.8%, the underlying issues, such as diagnostic delays and severe gut damage, could explain why anemia persists for some patients.
Ferrochel iron bisglycinate has effectively corrected my iron deficiency related to celiac disease, utilising a dual absorption mechanism. Its bioavailability approaches 90-100%, being 2.6 times safer than ferrous sulfate. I found that two doses in one capsule quickly raised my iron levels. Monitoring ferritin, instead of serum iron, is crucial in detecting anaemia. If you struggle with morning fatigue despite normal haemoglobin levels, checking ferritin will reveal much about your health. An equivalent from Russian pharmacies is Sideral forte, but it's considerably pricier.
Read More
9
Cost-effective iron solution
I purchased NOW Foods Iron Double Strength (36 mg, 90 Veggie Caps) and have noticed improvements in my energy levels within a couple of weeks. The vegetarian capsules are gentle on the stomach and do not cause the common side effects of other iron forms. They are free from allergens, and their long-term use is a great value for money, making them ideal for maintaining normal iron levels and enhancing overall health.
Read More
6
Improved haemoglobin levels
1 people found this helpful
This iron supplement helped me increase my haemoglobin from 108 to 132. Additionally, I incorporated vitamin C and B vitamins, while eliminating sugar, gluten, and dairy from my diet.
Read More
9
Powerful iron support
Super Double Strength Iron (36 mg) is a robust support for energy and blood health. Iron bisglycinate is better absorbed and does not irritate the gastrointestinal tract. The capsules, taken preferably on an empty stomach with vitamin C, help combat anaemia, reduce fatigue, and are beneficial for pregnant women. Additionally, they support healthy skin, hair, and nails.
Read More
9
Significant health improvement
I have been using these vegetarian capsules for several months and the results have been tremendous. Prior to this, I felt tired and dizzy due to anaemia. Since starting them, I have gained energy and vitality. They are gluten, soy, and GMO free, easy to swallow, and have no side effects, which is a significant plus for me.
Celiac disease is a chronic autoimmune disorder that affects the small intestine, triggered by the consumption of gluten, a protein found in wheat, barley, and rye. When individuals with celiac disease consume gluten, their immune system reacts by damaging the lining of the small intestine, leading to malabsorption of nutrients. This can result in a variety of health issues, including gastrointestinal symptoms like diarrhea, bloating, and abdominal pain, as well as non-GI symptoms such as fatigue, anemia, and skin rashes.
Diagnosis of celiac disease typically involves blood tests for specific antibodies, followed by a biopsy of the small intestine to confirm intestinal damage. The only effective treatment for celiac disease is strict adherence to a gluten-free diet, which helps heal the intestine and alleviates symptoms. Living gluten-free can be challenging but is essential for preventing long-term health complications associated with the disease. Many people with celiac disease find success with a gluten-free diet by seeking out certified gluten-free products, becoming accustomed to reading food labels, and exploring alternative grains such as rice and quinoa.
Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.
In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.
Based on user reviews, the time it takes to see results from iron supplements for those with Celiac disease can vary, but many users report noticeable improvements within just a couple of weeks. For instance, one user experienced enhanced energy levels just two weeks after starting NOW Foods Iron Double Strength Read Review. Another user highlighted significant increases in haemoglobin and overall vitality after a few months on their chosen supplement Read Review.
It's also worth noting that users emphasize the importance of consistency and proper dietary support, such as incorporating vitamin C, which can aid absorption, as mentioned by a reviewer who saw their haemoglobin rise considerably Read Review. Those with ongoing dietary restrictions, like avoiding gluten and dairy, also benefit greatly from these supplements without gastrointestinal upset, making them an ideal choice for individuals managing Celiac disease Read Review.
The supplement in question is not explicitly supported by scientific research specifically addressing its efficacy for patients with celiac disease (CD). However, studies have shown that many individuals with CD experience persistent anemia and iron deficiency despite adhering to a gluten-free diet, which can suggest a need for additional nutritional support [1]. For instance, one study found that around 25% of newly diagnosed patients had anemia, with a significant portion improving after two years on a gluten-free diet [6].
Interestingly, another study focusing on children with celiac disease indicated that although iron supplementation was provided, the outcomes for ferritin levels showed no significant difference when compared to those not receiving supplementation [2]. This suggests that while certain supplements may be beneficial, their necessity could vary greatly among individuals, especially considering that many experience normalization of essential levels through dietary changes alone. Therefore, while some individuals may benefit from specific supplements, the overall support for a generalized supplement for celiac disease remains nuanced and warrants further tailored research.
Users have reported substantial improvements in their symptoms after incorporating iron supplements into their routines, specifically for conditions like iron deficiency related to Celiac disease. Many have experienced noticeable enhancements in energy levels within just a couple of weeks of starting their supplementation. For example, one user noted a rapid increase in energy and vitality after several months of taking a vegetarian iron capsule, which they described as gentle on the stomach and effective in combating fatigue Read Review. Another user shared that their haemoglobin levels rose significantly from 108 to 132, attributing their improved health partly to the integration of vitamin C alongside their iron supplement Read Review.
In addition, reviewers praised the ease of swallowing vegetarian capsules and highlighted the lack of gastrointestinal upset often associated with traditional iron forms. Users emphasized that the supplements not only helped with increasing iron levels but also contributed to overall well-being, reducing fatigue and aiding in the production of healthy red blood cells Read Review. It's important to note that individual results can vary, and while these anecdotal experiences are promising, factors like diet and consistency in supplementation may influence outcomes.
Based on user reviews, many individuals managing Celiac disease find that combining iron supplements with additional nutrients, like vitamin C and B vitamins, enhances their overall effectiveness. For instance, one user reported a significant increase in haemoglobin levels after pairing their iron supplementation with vitamin C and dietary changes, which included eliminating sugar, gluten, and dairy Read Review. This combination appears to optimize iron absorption and improve energy levels, which is especially beneficial for those experiencing fatigue related to iron deficiency.
Additionally, reviewers noted that iron supplements, particularly those that are gluten-free and designed for enhanced absorption, like Ferrochel Iron Bisglycinate, can provide a safety profile that is favorable for those with gluten sensitivities. These supplements are well tolerated, often without gastrointestinal upset, which is ideal for individuals with dietary restrictions Read Review. Overall, users emphasize the importance of pairing these iron supplements with supportive nutrients while adhering to a gluten-free diet to fully address their health needs.
Users have reported positive experiences with various iron supplements for treating iron deficiency associated with Celiac disease, particularly emphasizing the importance of the proper dose. Many recommend a dosage of around 36 mg, commonly found in products like NOW Foods Iron. One user noted a significant improvement in their energy levels within a couple of weeks of taking this specific dosage Read Review. Others highlighted that these doses, especially when paired with vitamin C, enhance absorption and overall effectiveness, helping to combat symptoms like fatigue and anemia Read Review.
Additionally, users have shared that the gentle nature of Ferrochel® Iron Bisglycinate is beneficial, as it reduces the risk of gastrointestinal discomfort often associated with iron supplements Read Review. The effectiveness in raising hemoglobin levels, such as an increase from 108 to 132 reported by one user, showcases the potential of an adequate 36 mg dose in addressing anemia resulting from Celiac disease Read Review. Overall, many users underscore the significance of selecting the right formulation and monitoring ferritin levels to accurately assess iron status and treatment efficacy.
9
Cost-effective iron solution
I purchased NOW Foods Iron Double Strength (36 mg, 90 Veggie Caps) and have noticed improvements in my energy levels within a couple of weeks. The vegetarian capsules are gentle on the stomach and do not cause the common side effects of other iron forms. They are free from allergens, and their long-term use is a great value for money, making them ideal for maintaining normal iron levels and enhancing overall health.
9
Significant health improvement
I have been using these vegetarian capsules for several months and the results have been tremendous. Prior to this, I felt tired and dizzy due to anaemia. Since starting them, I have gained energy and vitality. They are gluten, soy, and GMO free, easy to swallow, and have no side effects, which is a significant plus for me.
6
Improved haemoglobin levels
1 people found this helpful
This iron supplement helped me increase my haemoglobin from 108 to 132. Additionally, I incorporated vitamin C and B vitamins, while eliminating sugar, gluten, and dairy from my diet.
8
Gentle but effective
Iron 36 mg by NOW is an effective supplement for healthy red blood cell production. This product utilises Ferrochel® Iron Bisglycinate, which is gentler and has lower chances of gastrointestinal discomfort. It is free from gluten, dairy, and soy, providing improved energy and reduced fatigue, particularly beneficial for those with iron deficiency anaemia. The capsules are easy to swallow, making daily intake hassle-free and cost-effective for anyone needing to boost their iron levels.
9
Effective iron supplement
1 people found this helpful
Ferrochel iron bisglycinate has effectively corrected my iron deficiency related to celiac disease, utilising a dual absorption mechanism. Its bioavailability approaches 90-100%, being 2.6 times safer than ferrous sulfate. I found that two doses in one capsule quickly raised my iron levels. Monitoring ferritin, instead of serum iron, is crucial in detecting anaemia. If you struggle with morning fatigue despite normal haemoglobin levels, checking ferritin will reveal much about your health. An equivalent from Russian pharmacies is Sideral forte, but it's considerably pricier.
9
Powerful iron support
Super Double Strength Iron (36 mg) is a robust support for energy and blood health. Iron bisglycinate is better absorbed and does not irritate the gastrointestinal tract. The capsules, taken preferably on an empty stomach with vitamin C, help combat anaemia, reduce fatigue, and are beneficial for pregnant women. Additionally, they support healthy skin, hair, and nails.
4
Long-term anemia remains in Celiac
Persistence of anemia in patients with Celiac disease despite a gluten free diet: a retrospective study.
We examined the prevalence of anemia in patients with Celiac Disease (CD) before and after they started a gluten-free diet (GFD). Through our cross-sectional study, we gathered blood data from 311 participants over the years, revealing that 17.8% of adults and 4.4% of children still struggled with anemia even after several years on the GFD.
While adults showed some improvement over time, with anemia rates dropping from 24% to 17.8%, the underlying issues, such as diagnostic delays and severe gut damage, could explain why anemia persists for some patients.
9.5
Iron treatment benefits in celiac disease
Anemia Etiology and the Response to a Gluten-Free Diet in Untreated Patients With Celiac Disease: A 2-Year Follow-Up.
We explored how iron deficiency and anemia affect individuals diagnosed with celiac disease (CeD) and the role of a gluten-free diet (GFD) in treating these issues. In a study of 572 patients, about 25% had anemia at the time of diagnosis, with iron deficiency being a major cause.
Interestingly, nearly 90% of those with anemia saw their hemoglobin levels return to normal after two years on a GFD. This suggests a positive response to dietary changes, helping many restore their health through improved nutrition.
4
Iron supplementation not significantly beneficial
Iron deficiency without anemia in children with newly diagnosed celiac disease: 1-year follow-up of ferritin levels, with and without iron supplementation.
We examined the effectiveness of iron supplementation in children with newly diagnosed celiac disease who have iron deficiency. Our study reviewed the ferritin levels of these kids on a gluten-free diet over a year.
Interestingly, we found that both those taking iron and those not taking it showed significant increases in ferritin levels. However, there was no marked difference in the outcomes between the two groups. Most importantly, children who adhered to a gluten-free diet tended to normalize their ferritin levels without needing iron supplements.
References
Valvano M, Giansante C, Vinci A, Maurici M, Fabiani S, et al. Persistence of anemia in patients with Celiac disease despite a gluten free diet: a retrospective study. BMC Gastroenterol. 2025;25:128. 10.1186/s12876-025-03712-6
Ben-Ami T, Trotskovsky A, Topf-Olivestone C, Kori M. Iron deficiency without anemia in children with newly diagnosed celiac disease: 1-year follow-up of ferritin levels, with and without iron supplementation. Eur J Pediatr. 2024;183:4705. 10.1007/s00431-024-05721-1
Raju SA, Greenaway EA, Schiepatti A, Arpa G, Vecchione N, et al. New entity of adult ultra-short coeliac disease: the first international cohort and case-control study. Gut. 2024;73:1124. 10.1136/gutjnl-2023-330913
Hujoel IA, Hujoel MLA. Investigating the role of iron status in the development of coeliac disease: a Mendelian randomisation study. BMJ Open Gastroenterol. 2024;11. 10.1136/bmjgast-2023-001236
Mumtaz A, Khan QA, Asim N, Baqi A, Iram S, et al. Diagnostic dilemma of celiac disease presenting with weight loss and secondary amenorrhea: A case report. Medicine (Baltimore). 2022;101:e31350. 10.1097/MD.0000000000031350
Roldan GA, Goyes D, Villafuerte-Gálvez JA, Urquiaga M, Dennis M, et al. Anemia Etiology and the Response to a Gluten-Free Diet in Untreated Patients With Celiac Disease: A 2-Year Follow-Up. Am J Gastroenterol. 2022;117:1684. 10.14309/ajg.0000000000001875