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SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Medium or Average
Based on 36 Reviews
6.7
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 180 mg Ferrous Bisglycinate)(Ferrochel™)
36 mg
200%
Top Medical Research Studies
9
Iron enhances piglet gut health
Dietary Fe-Gly supplementation attenuates enterotoxigenic (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets.
Study focused on diarrhea reduction
We explored how adding iron, specifically Fe-Gly, to piglets' diets could help combat diarrhea caused by enterotoxigenic E. coli (ETEC) infections. In our study, we administered 50 mg of Fe-Gly to weaned piglets that had been infected, monitoring their growth, diarrhea rates, and overall gut health.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
Read More
7
Iron's mixed effects on diarrhea
Application of longitudinal multilevel zero inflated Poisson regression in modeling of infectious diseases among infants in Ethiopia.
Limited ability to isolate iron effects
We explored the effect of iron supplementation in the form of Micronutrient Powder (MNP) on the duration of diarrhea among infants aged 6 to 11 months. By analyzing longitudinal data, we utilized a sophisticated statistical approach that considered the unique patterns of each child’s health over time.
Our findings revealed some interesting trends. Initially, infants using low-dose iron seemed to experience a greater number of days with diarrhea compared to those who did not use it. However, this pattern flipped as time went on, suggesting that the immediate benefits may vary.
Additionally, we noticed that infants who practiced exclusive breastfeeding for the first six months and supplemented with MNP reported fewer instances of respiratory issues. Overall, we observed that while iron treatment had some impact on respiratory infections, its direct effect on diarrhea was not straightforward.
Therefore, while iron supplementation can be beneficial in some contexts, the results point towards a more complex interaction with diarrhea in infants. This emphasizes the necessity of further investigation into dietary and health practices to enhance child health in our communities.
Our findings revealed some interesting trends. Initially, infants using low-dose iron seemed to experience a greater number of days with diarrhea compared to those who did not use it. However, this pattern flipped as time went on, suggesting that the immediate benefits may vary.
Additionally, we noticed that infants who practiced exclusive breastfeeding for the first six months and supplemented with MNP reported fewer instances of respiratory issues. Overall, we observed that while iron treatment had some impact on respiratory infections, its direct effect on diarrhea was not straightforward.
Therefore, while iron supplementation can be beneficial in some contexts, the results point towards a more complex interaction with diarrhea in infants. This emphasizes the necessity of further investigation into dietary and health practices to enhance child health in our communities.
Read More
4
No significant diarrhea increase
Effects of iron supplements and iron-containing micronutrient powders on the gut microbiome in Bangladeshi infants: a randomized controlled trial.
Investigates iron's safety profile.
We conducted a study to evaluate how iron supplements and iron-containing micronutrient powders (MNPs) affect the gut microbiome and the incidence of diarrhea in infants from rural Bangladesh. Over the course of three months, we gave 923 infants either iron, MNPs, or a placebo while monitoring their gut health.
Interestingly, we found no significant increase in diarrhea among the infants receiving iron supplements or MNPs compared to those given the placebo. This gives us a bit of reassurance regarding the safety of these interventions. Our primary analysis showed no substantial changes in gut microbiome diversity or composition after the treatments.
However, it's worth noting that when we looked closer—without adjusting for multiple comparisons—we observed some changes. Infants receiving iron and MNPs showed a reduction in beneficial gut bacteria, like Bifidobacterium and Lactobacillus, alongside an increase in potentially harmful species like Clostridium. These shifts were more pronounced in infants who already had enough iron at the start of the study.
Overall, while there was no significant increase in diarrhea, the observed shifts in the gut microbiome could raise concerns, especially in well-nourished infants. Our findings highlight the need for further research to understand the complexities of iron treatment fully.
Interestingly, we found no significant increase in diarrhea among the infants receiving iron supplements or MNPs compared to those given the placebo. This gives us a bit of reassurance regarding the safety of these interventions. Our primary analysis showed no substantial changes in gut microbiome diversity or composition after the treatments.
However, it's worth noting that when we looked closer—without adjusting for multiple comparisons—we observed some changes. Infants receiving iron and MNPs showed a reduction in beneficial gut bacteria, like Bifidobacterium and Lactobacillus, alongside an increase in potentially harmful species like Clostridium. These shifts were more pronounced in infants who already had enough iron at the start of the study.
Overall, while there was no significant increase in diarrhea, the observed shifts in the gut microbiome could raise concerns, especially in well-nourished infants. Our findings highlight the need for further research to understand the complexities of iron treatment fully.
Read More
Most Useful Reviews
9.5
No issues noted
Excellent hardware! I occasionally take iron as my ferritin levels were found to be low (17). This iron is gentle on my gastrointestinal tract and does not cause diarrhoea. Previously, I used Solgar's soft iron, but this has a better dosage of 36 mg instead of 25 mg, which is more effective. It’s best taken with vitamin C or B vitamins for better absorption. I recommend it for those with low ferritin, pregnant or lactating women, and menstruating women.
Read More
9.5
Effective iron supplement
After two months of using pharmaceutical iron, I only experienced diarrhoea without any benefits. I switched to this supplement and felt improvements within three weeks: my complexion improved, energy levels rose, and irritability decreased. My ferritin increased from 8 to 48 along with hemoglobin levels. I definitely recommend it!
Read More
10
No side effects
I have long-standing iron deficiency anaemia but cannot take prescription drugs due to vomiting and diarrhoea. After taking this chelated iron for two months, my ferritin level increased from single digits to 40, which was a significant improvement. I will continue using it, and I noticed more hair growth since starting the supplement.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
9
Iron enhances piglet gut health
Dietary Fe-Gly supplementation attenuates enterotoxigenic (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets.
Study focused on diarrhea reduction
We explored how adding iron, specifically Fe-Gly, to piglets' diets could help combat diarrhea caused by enterotoxigenic E. coli (ETEC) infections. In our study, we administered 50 mg of Fe-Gly to weaned piglets that had been infected, monitoring their growth, diarrhea rates, and overall gut health.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
Read More
7
Iron's mixed effects on diarrhea
Application of longitudinal multilevel zero inflated Poisson regression in modeling of infectious diseases among infants in Ethiopia.
Limited ability to isolate iron effects
We explored the effect of iron supplementation in the form of Micronutrient Powder (MNP) on the duration of diarrhea among infants aged 6 to 11 months. By analyzing longitudinal data, we utilized a sophisticated statistical approach that considered the unique patterns of each child’s health over time.
Our findings revealed some interesting trends. Initially, infants using low-dose iron seemed to experience a greater number of days with diarrhea compared to those who did not use it. However, this pattern flipped as time went on, suggesting that the immediate benefits may vary.
Additionally, we noticed that infants who practiced exclusive breastfeeding for the first six months and supplemented with MNP reported fewer instances of respiratory issues. Overall, we observed that while iron treatment had some impact on respiratory infections, its direct effect on diarrhea was not straightforward.
Therefore, while iron supplementation can be beneficial in some contexts, the results point towards a more complex interaction with diarrhea in infants. This emphasizes the necessity of further investigation into dietary and health practices to enhance child health in our communities.
Our findings revealed some interesting trends. Initially, infants using low-dose iron seemed to experience a greater number of days with diarrhea compared to those who did not use it. However, this pattern flipped as time went on, suggesting that the immediate benefits may vary.
Additionally, we noticed that infants who practiced exclusive breastfeeding for the first six months and supplemented with MNP reported fewer instances of respiratory issues. Overall, we observed that while iron treatment had some impact on respiratory infections, its direct effect on diarrhea was not straightforward.
Therefore, while iron supplementation can be beneficial in some contexts, the results point towards a more complex interaction with diarrhea in infants. This emphasizes the necessity of further investigation into dietary and health practices to enhance child health in our communities.
Read More
4
No significant diarrhea increase
Effects of iron supplements and iron-containing micronutrient powders on the gut microbiome in Bangladeshi infants: a randomized controlled trial.
Investigates iron's safety profile.
We conducted a study to evaluate how iron supplements and iron-containing micronutrient powders (MNPs) affect the gut microbiome and the incidence of diarrhea in infants from rural Bangladesh. Over the course of three months, we gave 923 infants either iron, MNPs, or a placebo while monitoring their gut health.
Interestingly, we found no significant increase in diarrhea among the infants receiving iron supplements or MNPs compared to those given the placebo. This gives us a bit of reassurance regarding the safety of these interventions. Our primary analysis showed no substantial changes in gut microbiome diversity or composition after the treatments.
However, it's worth noting that when we looked closer—without adjusting for multiple comparisons—we observed some changes. Infants receiving iron and MNPs showed a reduction in beneficial gut bacteria, like Bifidobacterium and Lactobacillus, alongside an increase in potentially harmful species like Clostridium. These shifts were more pronounced in infants who already had enough iron at the start of the study.
Overall, while there was no significant increase in diarrhea, the observed shifts in the gut microbiome could raise concerns, especially in well-nourished infants. Our findings highlight the need for further research to understand the complexities of iron treatment fully.
Interestingly, we found no significant increase in diarrhea among the infants receiving iron supplements or MNPs compared to those given the placebo. This gives us a bit of reassurance regarding the safety of these interventions. Our primary analysis showed no substantial changes in gut microbiome diversity or composition after the treatments.
However, it's worth noting that when we looked closer—without adjusting for multiple comparisons—we observed some changes. Infants receiving iron and MNPs showed a reduction in beneficial gut bacteria, like Bifidobacterium and Lactobacillus, alongside an increase in potentially harmful species like Clostridium. These shifts were more pronounced in infants who already had enough iron at the start of the study.
Overall, while there was no significant increase in diarrhea, the observed shifts in the gut microbiome could raise concerns, especially in well-nourished infants. Our findings highlight the need for further research to understand the complexities of iron treatment fully.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 36 Reviews
6.7
10
No side effects
I have long-standing iron deficiency anaemia but cannot take prescription drugs due to vomiting and diarrhoea. After taking this chelated iron for two months, my ferritin level increased from single digits to 40, which was a significant improvement. I will continue using it, and I noticed more hair growth since starting the supplement.
Read More
10
Maintained iron levels
I have suffered from chronic anaemia for many years, complicating my efforts to conceive. I cannot tolerate pharmaceutical preparations due to diarrhoea. After starting this iron supplement, my ferritin rose from 7 to 32 in two months, and later, I successfully got pregnant with twins. I continue to take it to maintain my ferritin levels.
Read More
9.5
No issues noted
Excellent hardware! I occasionally take iron as my ferritin levels were found to be low (17). This iron is gentle on my gastrointestinal tract and does not cause diarrhoea. Previously, I used Solgar's soft iron, but this has a better dosage of 36 mg instead of 25 mg, which is more effective. It’s best taken with vitamin C or B vitamins for better absorption. I recommend it for those with low ferritin, pregnant or lactating women, and menstruating women.
Read More
9.5
Effective iron supplement
After two months of using pharmaceutical iron, I only experienced diarrhoea without any benefits. I switched to this supplement and felt improvements within three weeks: my complexion improved, energy levels rose, and irritability decreased. My ferritin increased from 8 to 48 along with hemoglobin levels. I definitely recommend it!
Read More
9.5
No stomach pain
I have problems with anaemia, and taking supplements usually causes stomach pain and diarrhoea. However, after starting this iron supplement, my stomach no longer hurts, my pallor improved, and I feel less dizzy and weak. For that reason alone, I would certainly recommend this product.
Read More
