Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Moderately Good
Based on 86 Reviews
7.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 180 mg Ferrous Bisglycinate)(Ferrochel™)
36 mg
200%
Top Medical Research Studies
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Read More
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Read More
7
We explored the effects of daily versus three times weekly (TIW) oral iron supplementation on nausea in NCAA Division 1 female athletes. The study involved 33 athletes who were either in track and field or soccer. Participants were given either daily doses or TIW doses of ferrous bisglycinate over eight weeks.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Read More
Most Useful Reviews
9
No nausea
391 people found this helpful
Awesome working additive! I ordered this iron for a friend suffering from muscle myositis. She struggled with low haemoglobin and fatigue, trying various pharmacy drugs with nausea as a side effect. After taking this for 3 months, her haemoglobin rose from 117 to 143, and the product caused no nausea. She's feeling great at work now! I also ordered it for myself for preventative measures. Thank you to the manufacturers for such a wonderful product!
Read More
9
Feeling better
62 people found this helpful
I've suffered from anaemia for years, trying many preparations that caused nausea. I like this drug for its dosage and the absence of side effects. After two weeks, I started feeling better; there’s less fatigue, and I plan to retake my tests soon. Click "yes" if you agree!
Read More
9
No side effects
57 people found this helpful
This chelated form of bisglycinate does not cause nausea or constipation. My tests indicate it's effective, and I highly recommend it to others!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
- All Researches
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Read More
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Read More
7
We explored the effects of daily versus three times weekly (TIW) oral iron supplementation on nausea in NCAA Division 1 female athletes. The study involved 33 athletes who were either in track and field or soccer. Participants were given either daily doses or TIW doses of ferrous bisglycinate over eight weeks.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Read More
7
Ferric carboxymaltose reduces nausea
This randomized controlled trial explored how low-dose ferric carboxymaltose (FCM) affects hemoglobin levels and nausea in postpartum East Asian women. Participants received either an intravenous FCM infusion or oral iron for four weeks.
We found that while FCM significantly increased hemoglobin levels after two weeks, both treatments showed no significant difference in final hemoglobin results after four weeks.
Notably, the FCM group experienced fewer gastrointestinal side effects, including nausea, suggesting it may be a more comfortable option for new mothers.
We found that while FCM significantly increased hemoglobin levels after two weeks, both treatments showed no significant difference in final hemoglobin results after four weeks.
Notably, the FCM group experienced fewer gastrointestinal side effects, including nausea, suggesting it may be a more comfortable option for new mothers.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 86 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
No nausea
391 people found this helpful
Awesome working additive! I ordered this iron for a friend suffering from muscle myositis. She struggled with low haemoglobin and fatigue, trying various pharmacy drugs with nausea as a side effect. After taking this for 3 months, her haemoglobin rose from 117 to 143, and the product caused no nausea. She's feeling great at work now! I also ordered it for myself for preventative measures. Thank you to the manufacturers for such a wonderful product!
Read More
9
Feeling better
62 people found this helpful
I've suffered from anaemia for years, trying many preparations that caused nausea. I like this drug for its dosage and the absence of side effects. After two weeks, I started feeling better; there’s less fatigue, and I plan to retake my tests soon. Click "yes" if you agree!
Read More
9
No side effects
57 people found this helpful
This chelated form of bisglycinate does not cause nausea or constipation. My tests indicate it's effective, and I highly recommend it to others!
Read More
9
No discomfort
46 people found this helpful
I'm amazed by the results of this iron. After a year of low haemoglobin, I switched from painful iron supplements to this one. I felt better physically after weeks and my haemoglobin rose from 113 to 144 without any nausea or discomfort. I highly recommend it!
Read More
9
No nausea
37 people found this helpful
I ordered this for my mother, who cannot tolerate other iron supplements that cause severe nausea. There are no side effects with this product, making it an excellent choice for her.
Read More
Frequently Asked Questions
9
Feeling better
62 people found this helpful
I've suffered from anaemia for years, trying many preparations that caused nausea. I like this drug for its dosage and the absence of side effects. After two weeks, I started feeling better; there’s less fatigue, and I plan to retake my tests soon. Click "yes" if you agree!
9
No discomfort
46 people found this helpful
I'm amazed by the results of this iron. After a year of low haemoglobin, I switched from painful iron supplements to this one. I felt better physically after weeks and my haemoglobin rose from 113 to 144 without any nausea or discomfort. I highly recommend it!
9
Reduced nausea
3 people found this helpful
I was advised to take this after a blood test showed low ferritin at 22. I’m now on Ferm's 1 and Iron 3, and my levels have risen to 40. This supplement is easy to take without nausea, and I believe it will continue to help if I increase the dose.
9
No side effects noted
2 people found this helpful
This iron supplements is excellent and readily absorbed by the body. I take only this one and have eliminated the usual side effects from conventional iron, such as constipation and nausea. I highly recommend it.
0
Nausea reported
6 people found this helpful
Unfortunately, this drug did not suit me due to strong side effects, specifically nausea and vomiting, even when taken with meals.
9
No nausea side effects
4 people found this helpful
I noticed an improvement in my anaemia during my period, which worsened due to heavy menstrual flow. This supplement improved my condition without the usual nausea or bowel issues that prescription medications caused. I also take it with vitamin C to aid absorption, and I plan to continue using it regularly as iron from food is hard to get.
0
Nausea experienced
8 people found this helpful
I began taking these pills to raise ferritin, but after a week, I experienced nausea, constipation, and intestinal pain. Despite having a healthy gut, I cannot recommend this drug.
9
No nausea
391 people found this helpful
Awesome working additive! I ordered this iron for a friend suffering from muscle myositis. She struggled with low haemoglobin and fatigue, trying various pharmacy drugs with nausea as a side effect. After taking this for 3 months, her haemoglobin rose from 117 to 143, and the product caused no nausea. She's feeling great at work now! I also ordered it for myself for preventative measures. Thank you to the manufacturers for such a wonderful product!
0
Severe nausea
5 people found this helpful
I have a sensitive stomach. After taking this iron supplement, which has a high absorption rate due to my low ferritin at 19, I experienced nausea, stomachache, and constipation. It did not suit me, and I am considering switching to a Japanese iron supplement.
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
References
- Srivastav A, Kshirsagar S, Adhav T, Ganu G, Shah A. Efficacy and Safety of Microsomal Ferric Pyrophosphate Supplement for Iron Deficiency Anemia in Pregnancy. Cureus. 2024;16:e57108. doi:10.7759/cureus.57108
- Schulte J, Peterson K, Thomsen T, Lentz S, Hall M, et al. Daily versus three times weekly dosing for treatment of iron deficiency nonanemia in NCAA Division 1 female athletes. PM R. 2024;16:316. doi:10.1002/pmrj.13172
- Nagao T, Takahashi K, Takahashi S, Yokomizo R, Samura O, et al. Low-dose ferric carboxymaltose vs. oral iron for improving hemoglobin levels in postpartum East Asian women: A randomized controlled trial. PLoS One. 2025;20:e0319795. doi:10.1371/journal.pone.0319795
- Wada-Hiraike O, Maruyama A, Mitobe Y, Iriyama T, Mori-Uchino M, et al. A Multicenter Single-Arm Study of Switching to Ferric Citrate Hydrate for Iron Deficiency Anemia in Patients Intolerant to Oral Iron: RIO-SWITCH. Adv Ther. 2025. doi:10.1007/s12325-025-03123-9
