SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 4 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
Rutin Powder (from Sophora japonica Flower Bud)
25 mg

Top Medical Research Studies

7
Vitamin C's role in arthritis management
The role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review.
Focused on vitamin C's benefits
We explored the role of vitamin C in addressing arthritis symptoms, particularly its effect on joint inflammation. Vitamin C is known for its antioxidant properties, and we found that it plays a crucial role in collagen synthesis. This feature is important as collagen forms the structural basis of our joints.

What excited us was the possibility that vitamin C could help reduce inflammation in patients with rheumatoid arthritis. Given that inflammation is a major factor in the discomfort and damage associated with this condition, any reduction could significantly enhance the quality of life for those affected.

However, while vitamin C shows promise due to its supportive functions, we must remember that the evidence concerning its direct effectiveness on arthritis specifically is still evolving. The correlation between vitamin C intake and reduced joint inflammation points to a beneficial role, but more detailed studies are necessary to solidify these findings and determine optimal dosages.

Overall, our review highlights that while vitamin C may indeed support joint health and aid in managing inflammation, further research is essential to fully understand its impact and to evaluate how it can be integrated into arthritis management strategies effectively.
Read More
8
Vitamin C's potential against arthritis
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
Effectiveness requires combination context
We explored the role of vitamin C (VC) in combating rheumatoid arthritis (RA) using a rat model. The study focused on how VC works in combination with inorganic nitrates to prevent arthritis symptoms, presenting an interesting angle on potential treatments for this chronic inflammatory disease.

Our observations revealed that when nitrates and VC were combined, they significantly reduced swelling and arthritis scores in the rats. This combination also appeared to lead to improvements in bone health and a decrease in inflammation markers in the body. Histological and radiological examinations indicated that the rats relieved from symptoms showed less synovial hyperplasia and bone loss.

Interestingly, while VC alone couldn’t be fully isolated for its effects, it contributed to reducing critical inflammation indicators such as TNF-α and IL-1β. By working together, nitrates and VC seem to effectively inhibit key inflammatory processes, particularly a type of cell death known as pyroptosis in macrophages. This suggests a promising new pathway for RA prevention, where the synergy between these two substances plays a crucial role.
Read More

Most Useful Reviews

9.5
Joint pain relief
In one capsule, not only essential vitamin C, but also rutin and bioflavonoids. Rutin is known for its protective role for ascorbic acid (vitamin C) due to its antioxidant properties, which fend off excessive oxidation. Preparations from sophora are recommended for strengthening blood vessels. I have arthritis and can definitely say that my joints have become much less painful. This vitamin is particularly useful during heightened virus activity. My whole family takes it as an additional source of body protection, and we rarely suffer from respiratory illnesses. I appreciate the convenient dosage and reasonable pricing of this company's products, and I wholeheartedly recommend it.
Read More
9.5
Helpful for inflammation
I have been a loyal consumer of Thorne Pure Ascorbic Acid, but when they reduced the capsules, I searched for a replacement. I decided to try "NOW Foods, C-1000 with Bioflavonoids" due to its safe, vegetable-sourced ingredients. Although I don't have arthritis, my mother does, and this supplement has been helpful for her inflammation and pain. I manage my allergies effectively with this vitamin C, reducing my need for OTC allergy medications. These capsules are of acceptable size and are gentle on my stomach. I highly recommend giving it a try!
Read More
8.8
Effective ingredient
Perfect quality! The ingredient is beneficial for arthritis, the effect is noticeable, and my immunity has improved with the convenient packaging.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
8
Vitamin C's potential against arthritis
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
Effectiveness requires combination context
We explored the role of vitamin C (VC) in combating rheumatoid arthritis (RA) using a rat model. The study focused on how VC works in combination with inorganic nitrates to prevent arthritis symptoms, presenting an interesting angle on potential treatments for this chronic inflammatory disease.

Our observations revealed that when nitrates and VC were combined, they significantly reduced swelling and arthritis scores in the rats. This combination also appeared to lead to improvements in bone health and a decrease in inflammation markers in the body. Histological and radiological examinations indicated that the rats relieved from symptoms showed less synovial hyperplasia and bone loss.

Interestingly, while VC alone couldn’t be fully isolated for its effects, it contributed to reducing critical inflammation indicators such as TNF-α and IL-1β. By working together, nitrates and VC seem to effectively inhibit key inflammatory processes, particularly a type of cell death known as pyroptosis in macrophages. This suggests a promising new pathway for RA prevention, where the synergy between these two substances plays a crucial role.
Read More
7
Vitamin C's role in arthritis management
The role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review.
Focused on vitamin C's benefits
We explored the role of vitamin C in addressing arthritis symptoms, particularly its effect on joint inflammation. Vitamin C is known for its antioxidant properties, and we found that it plays a crucial role in collagen synthesis. This feature is important as collagen forms the structural basis of our joints.

What excited us was the possibility that vitamin C could help reduce inflammation in patients with rheumatoid arthritis. Given that inflammation is a major factor in the discomfort and damage associated with this condition, any reduction could significantly enhance the quality of life for those affected.

However, while vitamin C shows promise due to its supportive functions, we must remember that the evidence concerning its direct effectiveness on arthritis specifically is still evolving. The correlation between vitamin C intake and reduced joint inflammation points to a beneficial role, but more detailed studies are necessary to solidify these findings and determine optimal dosages.

Overall, our review highlights that while vitamin C may indeed support joint health and aid in managing inflammation, further research is essential to fully understand its impact and to evaluate how it can be integrated into arthritis management strategies effectively.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Joint pain relief
In one capsule, not only essential vitamin C, but also rutin and bioflavonoids. Rutin is known for its protective role for ascorbic acid (vitamin C) due to its antioxidant properties, which fend off excessive oxidation. Preparations from sophora are recommended for strengthening blood vessels. I have arthritis and can definitely say that my joints have become much less painful. This vitamin is particularly useful during heightened virus activity. My whole family takes it as an additional source of body protection, and we rarely suffer from respiratory illnesses. I appreciate the convenient dosage and reasonable pricing of this company's products, and I wholeheartedly recommend it.
Read More
9.5
Helpful for inflammation
I have been a loyal consumer of Thorne Pure Ascorbic Acid, but when they reduced the capsules, I searched for a replacement. I decided to try "NOW Foods, C-1000 with Bioflavonoids" due to its safe, vegetable-sourced ingredients. Although I don't have arthritis, my mother does, and this supplement has been helpful for her inflammation and pain. I manage my allergies effectively with this vitamin C, reducing my need for OTC allergy medications. These capsules are of acceptable size and are gentle on my stomach. I highly recommend giving it a try!
Read More
8.8
Effective ingredient
Perfect quality! The ingredient is beneficial for arthritis, the effect is noticeable, and my immunity has improved with the convenient packaging.
8
Rheumatoid arthritis control
Easy to swallow, I take these with others to manage my rheumatoid arthritis and to ward off illnesses. I love the NOW brand.

Frequently Asked Questions

No FAQs are available for this product and symptom.
image