4 of our family members use this vitamin to ward off migraines or stop them at the first symptom. Caffiene. cow's milk products, real chocolate etc loads the migraine pistol. Extreme stress pulls the trigger of that overloaded pistol. This yeast based B-50 vitamin builds a resistance to the symptoms (bright colors, Vertigo, head pain, nausea etc) and when taken at the onset of one, will immediately stop one. The dosage that was prescribed to my family is 2 capsules with each of the 3 meals, lessening the supper one first to 1 then lessen the lunch one. Keep the breakfast one at 2. Each of our family have a little different system. But they all take 5-6 capsules at the onset if one sneeks through. (More underlying stress not paid attention to.) It lessens the time where that awful fatigue recks a day