' 
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Thiamin (Vitamin B-1) (from Thiamin HCl)
50 mg
4167%
Riboflavin (Vitamin B-2)
50 mg
3846%
Niacin (Vitamin B-3) (as Niacinamide)
50 mg
313%
Vitamin B-6 (from Pyridoxine HCl)
50 mg
2941%
Folate
680 mcg DFE (400 mcg folic acid)
170%
Vitamin B-12 (as Cyanocobalamin)
50 mcg
2083%
Biotin
50 mcg
167%
Pantothenic Acid (from Calcium Pantothenate)
50 mg
1000%
Choline (from Choline Bitartrate)
25 mg
5%
PABA (Para-Aminobenzoic Acid)
25 mg
†
Inositol
25 mg
†
Top Medical Research Studies
8
Folic acid reduces clot events
Supplementation with Folic Acid and Cardiovascular Outcomes in End-Stage Kidney Disease: A Multi-Institution Cohort Study.
Research score: Moderate relevance
We examined the effects of folic acid supplementation on blood clot events in patients with end-stage kidney disease (ESKD). Analyzing data from over 2,000 patients, we divided them into daily and weekly supplementation groups for a mean follow-up of 5.8 years.
Our findings indicated that patients receiving daily folic acid had a lower rate of arteriovenous access thrombosis compared to those on a weekly regimen. However, we found no significant differences between the groups concerning major cardiovascular events or overall mortality.
More research is needed to fully understand the potential of folate in preventing thrombosis in this population.
Our findings indicated that patients receiving daily folic acid had a lower rate of arteriovenous access thrombosis compared to those on a weekly regimen. However, we found no significant differences between the groups concerning major cardiovascular events or overall mortality.
More research is needed to fully understand the potential of folate in preventing thrombosis in this population.
Read More
8
Folic acid mitigates coagulation risk
Folic acid targets splenic extramedullary hemopoiesis to attenuate carbon black-induced coagulation-thrombosis potential.
High relevance to blood clotting
We investigated how folic acid (FA) affects blood clotting in response to carbon black exposure. Adult mice were exposed to filtered air or carbon black for 28 days. We found that carbon black increased blood clotting and spurred the development of a certain type of blood cells in the spleen. Interestingly, while carbon black lowered folic acid levels, administering FA helped restore normal coagulation by inhibiting certain enzymes in spleen macrophages. This suggests that folic acid could be beneficial in protecting against increased clotting risks related to carbon black exposure.
Read More
8
Nitrous oxide use leads to health risks
A 19-Year-Old Man with a History of Recreational Inhalation of Nitrous Oxide with Severe Peripheral Neuropathy and Central Pulmonary Embolism.
High relevance for young users
In this case, we observed a 19-year-old man who developed severe peripheral neuropathy and central pulmonary embolism after using nitrous oxide recreationally. Elevated levels of homocysteine and methylmalonic acid indicated vitamin B₁₂ inactivation due to the substance. After discontinuing nitrous oxide and undergoing treatment with B vitamins for six months, the patient showed remarkable recovery, with symptoms significantly reduced. This highlights that even low levels of nitrous oxide use can lead to serious health issues, including increased blood clot risks. Awareness is crucial for young individuals who may use this substance.
Read More
Most Useful Reviews
8.8
Cardiovascular protection
Works well and aids in combating homocysteine. I've taken the second can of this complex with no side effects, and the positive effects are clear. B12 and folic acid are vital for lowering homocysteine, which can lead to blood clots. It serves as a good preventative measure for cardiovascular diseases when combined with Omega-3.
Read More
3.8
Excessive reactions
I sought to replenish my B vitamin levels and opted to take one every other day due to high daily percentage claims. My hair improved significantly, but after three weeks, I developed an itchy rash and experienced menstruation with large clots. I learned that too much B vitamins could be a cause. I stopped taking them, and the issues ceased. Be cautious when reading descriptions.
Read More
8
Energy restoration
A very good B vitamin complex, it contains everything necessary to restore the nervous system and boost energy. It can also augment blood haemoglobin levels alongside iron. My physician recommended it as a cofactor for better absorption, and I found the capsules easy to take.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
- All Researches
8
Vitamin B12 deficiency and thrombosis
Cerebral Venous Sinus Thrombosis Secondary to Vitamin B12 Deficiency - A Case Series with Emphasis on Food Fortification.
Case series, dietary implications
We examined the impact of vitamin B12 deficiency on cerebral venous sinus thrombosis (CVST) through a case series involving three patients. Each case presented symptoms like headaches and, in some instances, visual disturbances. All patients showed elevated homocysteine levels and had low vitamin B12. Treatment included anticoagulation therapy and vitamin supplementation, leading to positive responses and, in two cases, resolution of thrombosis. This suggests that monitoring vitamin B12 levels, particularly in vegetarian diets, is crucial and could help prevent CVST.
Read More
8
Vitamin B12 aids in thromboembolism recovery
Cerebral venous thrombosis associated with hyperhomocysteinemia and iron-deficiency anemia induced by autoimmune gastritis: A case report and literature review.
Case report on thrombosis treatment.
We observed a rare case of cerebral venous thrombosis (CVT) associated with hyperhomocysteinemia and iron-deficiency anemia due to autoimmune gastritis.
The patient, a 47-year-old woman, experienced serious symptoms like impaired consciousness and motor difficulties. After thorough examinations like CT and MRI, she was treated with anticoagulants and given iron and vitamin B12 supplements.
Remarkably, the patient showed significant improvement and was discharged without neurological deficits, highlighting the potential role of vitamin B12 and iron in managing conditions linked to blood clots.
The patient, a 47-year-old woman, experienced serious symptoms like impaired consciousness and motor difficulties. After thorough examinations like CT and MRI, she was treated with anticoagulants and given iron and vitamin B12 supplements.
Remarkably, the patient showed significant improvement and was discharged without neurological deficits, highlighting the potential role of vitamin B12 and iron in managing conditions linked to blood clots.
Read More
8
Folic acid reduces clot events
Supplementation with Folic Acid and Cardiovascular Outcomes in End-Stage Kidney Disease: A Multi-Institution Cohort Study.
Research score: Moderate relevance
We examined the effects of folic acid supplementation on blood clot events in patients with end-stage kidney disease (ESKD). Analyzing data from over 2,000 patients, we divided them into daily and weekly supplementation groups for a mean follow-up of 5.8 years.
Our findings indicated that patients receiving daily folic acid had a lower rate of arteriovenous access thrombosis compared to those on a weekly regimen. However, we found no significant differences between the groups concerning major cardiovascular events or overall mortality.
More research is needed to fully understand the potential of folate in preventing thrombosis in this population.
Our findings indicated that patients receiving daily folic acid had a lower rate of arteriovenous access thrombosis compared to those on a weekly regimen. However, we found no significant differences between the groups concerning major cardiovascular events or overall mortality.
More research is needed to fully understand the potential of folate in preventing thrombosis in this population.
Read More
8
Folic acid mitigates coagulation risk
Folic acid targets splenic extramedullary hemopoiesis to attenuate carbon black-induced coagulation-thrombosis potential.
High relevance to blood clotting
We investigated how folic acid (FA) affects blood clotting in response to carbon black exposure. Adult mice were exposed to filtered air or carbon black for 28 days. We found that carbon black increased blood clotting and spurred the development of a certain type of blood cells in the spleen. Interestingly, while carbon black lowered folic acid levels, administering FA helped restore normal coagulation by inhibiting certain enzymes in spleen macrophages. This suggests that folic acid could be beneficial in protecting against increased clotting risks related to carbon black exposure.
Read More
8
Nitrous oxide use leads to health risks
A 19-Year-Old Man with a History of Recreational Inhalation of Nitrous Oxide with Severe Peripheral Neuropathy and Central Pulmonary Embolism.
High relevance for young users
In this case, we observed a 19-year-old man who developed severe peripheral neuropathy and central pulmonary embolism after using nitrous oxide recreationally. Elevated levels of homocysteine and methylmalonic acid indicated vitamin B₁₂ inactivation due to the substance. After discontinuing nitrous oxide and undergoing treatment with B vitamins for six months, the patient showed remarkable recovery, with symptoms significantly reduced. This highlights that even low levels of nitrous oxide use can lead to serious health issues, including increased blood clot risks. Awareness is crucial for young individuals who may use this substance.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Cardiovascular protection
Works well and aids in combating homocysteine. I've taken the second can of this complex with no side effects, and the positive effects are clear. B12 and folic acid are vital for lowering homocysteine, which can lead to blood clots. It serves as a good preventative measure for cardiovascular diseases when combined with Omega-3.
Read More
3.8
Excessive reactions
I sought to replenish my B vitamin levels and opted to take one every other day due to high daily percentage claims. My hair improved significantly, but after three weeks, I developed an itchy rash and experienced menstruation with large clots. I learned that too much B vitamins could be a cause. I stopped taking them, and the issues ceased. Be cautious when reading descriptions.
Read More
8
Energy restoration
A very good B vitamin complex, it contains everything necessary to restore the nervous system and boost energy. It can also augment blood haemoglobin levels alongside iron. My physician recommended it as a cofactor for better absorption, and I found the capsules easy to take.
4.8
Blood pressure drop
On the second day of taking these, my blood pressure dropped (100/60). It seems the dosage is quite high for my weight of 45 kg. I’ll try taking it every other day instead. It does help calm my nerves and reduces my sense of anxiety.
