SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 4 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
10 mcg (400 IU)
50%
Top Medical Research Studies
8
Genetic factors in cold sores
Associations between host genetic variants and Herpes Simplex Labialis in the TwinsUK cohort.
Genetic variant relevance acknowledged
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Read More
Most Useful Reviews
9.5
Miracle vitamin
If I had known earlier how this miracle vitamin could combat colds and flu, I would have taken it sooner. Vitamin D3 is an incredible prohormone that strengthens bone structure and protects against viruses, bacteria, and fungi. I’ve recommended it to everyone.
Read More
9.5
Highly recommended
I often caught colds but rarely do now, thanks to this vitamin and zinc. Vitamin D3 has significantly improved my immunity during the Covid period. I recommend everyone takes it, especially during winter.
Read More
9.5
Boosts immunity effectively
My favourite for boosting immunity! This is the best vitamin D3 I have tried. The small capsules are convenient to swallow and tasteless, making them easy to give to children. I take 2-3 daily. With insufficient sunlight, vitamin D is essential for the body during colds and helps strengthen the immune system, especially with the ongoing coronavirus threat.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Genetic factors in cold sores
Associations between host genetic variants and Herpes Simplex Labialis in the TwinsUK cohort.
Genetic variant relevance acknowledged
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Miracle vitamin
If I had known earlier how this miracle vitamin could combat colds and flu, I would have taken it sooner. Vitamin D3 is an incredible prohormone that strengthens bone structure and protects against viruses, bacteria, and fungi. I’ve recommended it to everyone.
9.5
Highly recommended
I often caught colds but rarely do now, thanks to this vitamin and zinc. Vitamin D3 has significantly improved my immunity during the Covid period. I recommend everyone takes it, especially during winter.
9.5
Boosts immunity effectively
My favourite for boosting immunity! This is the best vitamin D3 I have tried. The small capsules are convenient to swallow and tasteless, making them easy to give to children. I take 2-3 daily. With insufficient sunlight, vitamin D is essential for the body during colds and helps strengthen the immune system, especially with the ongoing coronavirus threat.
Read More
8.8
Treats cold sores
Everyone should buy this! It’s essential for people who work indoors and lack sunlight, as vitamin D deficiency leads to bone loss and depression. I find it effective for both depression and immunity. After a month of taking this, my cold sores disappeared.
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