Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.3
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.9
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
7,500 mcg
833%

Top Medical Research Studies

We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.
Read More
7
ATRA shows mixed effects on pain
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.

Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.

Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Read More

Most Useful Reviews

9
Effective for bone pain
7 people found this helpful
I purchased this hoping to enhance my vision and improve my mucous membranes. Surprisingly, it was remarkably effective against my bone pain associated with hernias. After starting it, my back pain resolved in just four days. When I resumed taking it after a minor back injury, it worked instantly. I feel the combination with B vitamins has a positive effect, and while I'm unsure about my eyesight, my skin appears clearer.
Read More
9
Prevents bone pain
2 people found this helpful
I’ve managed my gout with medications for lowering uric acid, but I've read that vitamin A can help prevent bone pain. Initially, I took multiple liver oil tablets daily, but this product's high IU value allows me to take just one or two. It seems more effective when combined with 2g of vitamin C.
Read More
9
Eased bone pain
1 people found this helpful
Excellent! My bone pain has eased significantly. There's no need for compresses anymore.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.3
  • All Researches
We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.
Read More
7
ATRA shows mixed effects on pain
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.

Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.

Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 9 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective for bone pain
7 people found this helpful
I purchased this hoping to enhance my vision and improve my mucous membranes. Surprisingly, it was remarkably effective against my bone pain associated with hernias. After starting it, my back pain resolved in just four days. When I resumed taking it after a minor back injury, it worked instantly. I feel the combination with B vitamins has a positive effect, and while I'm unsure about my eyesight, my skin appears clearer.
Read More
9
Prevents bone pain
2 people found this helpful
I’ve managed my gout with medications for lowering uric acid, but I've read that vitamin A can help prevent bone pain. Initially, I took multiple liver oil tablets daily, but this product's high IU value allows me to take just one or two. It seems more effective when combined with 2g of vitamin C.
Read More
9
Eased bone pain
1 people found this helpful
Excellent! My bone pain has eased significantly. There's no need for compresses anymore.
Read More
9
Reduced bone pain
1 people found this helpful
Since my cancer diagnosis and reconstruction, I’ve suffered from joint pain and inflammation. Since starting NAC over two years ago, I’ve noticed a huge difference; my bone pain has greatly diminished. I store them in the fridge due to a sulphur smell, but they haven’t caused any upset.
Read More
0
Stopped due to pain
4 people found this helpful
When I took this daily, I experienced joint pain and brittle bones, so I've stopped. I hadn’t realised that excessive vitamin A could be harmful. I wonder if my body will recover to its original state.
Read More

Frequently Asked Questions

9
Effective for bone pain
7 people found this helpful
I purchased this hoping to enhance my vision and improve my mucous membranes. Surprisingly, it was remarkably effective against my bone pain associated with hernias. After starting it, my back pain resolved in just four days. When I resumed taking it after a minor back injury, it worked instantly. I feel the combination with B vitamins has a positive effect, and while I'm unsure about my eyesight, my skin appears clearer.
7.5
Improved bone pain
3 people found this helpful
After five days of use, my severe dry eye syndrome significantly improved, and my bone pain was also alleviated. I no longer feel pain in my eyes, and the acne on my skin has improved as well. However, I understand that long-term use of vitamin A isn't advisable, so I may take it again after a break.
7.5
Joint pain relief
1 people found this helpful
Works well! After spraining my elbow joint, the pain subsided. I just need to take it for a longer duration.
7.5
Bone pain management
1 people found this helpful
I’ve been taking it for nearly three years due to collagen disease. My health is gradually improving; even after having my lower wisdom tooth removed, I didn't experience severe bone pain post-extraction. I took an extra pill beforehand, which may have helped in avoiding discomfort.
9
Eased bone pain
1 people found this helpful
Excellent! My bone pain has eased significantly. There's no need for compresses anymore.
9
Prevents bone pain
2 people found this helpful
I’ve managed my gout with medications for lowering uric acid, but I've read that vitamin A can help prevent bone pain. Initially, I took multiple liver oil tablets daily, but this product's high IU value allows me to take just one or two. It seems more effective when combined with 2g of vitamin C.
9
Reduced bone pain
1 people found this helpful
Since my cancer diagnosis and reconstruction, I’ve suffered from joint pain and inflammation. Since starting NAC over two years ago, I’ve noticed a huge difference; my bone pain has greatly diminished. I store them in the fridge due to a sulphur smell, but they haven’t caused any upset.
0
Stopped due to pain
4 people found this helpful
When I took this daily, I experienced joint pain and brittle bones, so I've stopped. I hadn’t realised that excessive vitamin A could be harmful. I wonder if my body will recover to its original state.
7
ATRA shows mixed effects on pain
We explored the effects of all-trans retinoic acid (ATRA) when combined with dexamethasone and alpha-interferon in treating advanced multiple myeloma. Out of 10 treated patients, eight completed the regimen.

Notably, three experienced a stable plateau phase with improvement in their overall performance and relief from bone pain. However, only two showed a lasting partial response, while three patients did not improve.

Thus, while there was some positive impact on bone pain, further research is needed to confirm these findings and assess ATRA's full potential.
We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.

References

  1. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102:556. doi:10.1136/archdischild-2016-310631
  2. Musto P, Sajeva MR, Sanpaolo G, D'Arena G, Scalzulli PR, et al. All-trans retinoic acid in combination with alpha-interferon and dexamethasone for advanced multiple myeloma. Haematologica. 1997;82:354.
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