5/15/2025
Last update
5/15/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 64 Reviews
8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
7,500 mcg
833%
Top Medical Research Studies
9
We explored how vitamin A affects our body’s response to cold, specifically looking at its role in transforming white fat into brown fat, a process known as browning. This transformation is significant, as it can help reduce obesity and improve metabolic health.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
Read More
Most Useful Reviews
9
Effective in winter
6 people found this helpful
I tend to have dry mucous membranes in my throat and nose, often leading to colds. I started with a small amount, but only realised its effect on dryness when I increased my intake to 25,000 to 50,000 IU. My supplement intake increases in winter, and thanks to it, I seldom catch colds.
Read More
9
Effective for cold
5 people found this helpful
I have been on a high protein diet for several years and take vitamin A every night, usually 1 tablet. When my throat feels uncomfortable, I take 2 tablets. I also take over 5g of vitamin C, and the signs of a cold usually disappear by the next morning. It is an essential supplement.
Read More
9
Quick cold remedy
4 people found this helpful
I have been using vitamin A throughout my adult life for myself and my children when they start to sniffle. The cold typically goes away in 2-3 days. Unfortunately, it's less available in pharmacies now due to a fear campaign, but it is also a wonderful sleep aid that induces deep, restful sleep without side effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We explored how vitamin A affects our body’s response to cold, specifically looking at its role in transforming white fat into brown fat, a process known as browning. This transformation is significant, as it can help reduce obesity and improve metabolic health.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
Read More
User Reviews
USERS' SCORE
Good
Based on 64 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective in winter
6 people found this helpful
I tend to have dry mucous membranes in my throat and nose, often leading to colds. I started with a small amount, but only realised its effect on dryness when I increased my intake to 25,000 to 50,000 IU. My supplement intake increases in winter, and thanks to it, I seldom catch colds.
Read More
9
Effective for cold
5 people found this helpful
I have been on a high protein diet for several years and take vitamin A every night, usually 1 tablet. When my throat feels uncomfortable, I take 2 tablets. I also take over 5g of vitamin C, and the signs of a cold usually disappear by the next morning. It is an essential supplement.
Read More
9
Quick cold remedy
4 people found this helpful
I have been using vitamin A throughout my adult life for myself and my children when they start to sniffle. The cold typically goes away in 2-3 days. Unfortunately, it's less available in pharmacies now due to a fear campaign, but it is also a wonderful sleep aid that induces deep, restful sleep without side effects.
Read More
9
Improved immune response
1 people found this helpful
NOW Foods Vitamin A 25,000 IU Softgels are crucial for my health. They support eye health and strengthen my immune system. I’ve noticed fewer colds, even during seasonal changes. The softgel format is easy to incorporate into my routine, and the price is reasonable. I plan to keep taking them!
Read More
9
Effective against cold
1 people found this helpful
Works great for me. I take this daily, but at the first sign of a cold or virus, I increase to 100,000 IU for three days and see a significant difference compared to not taking it!
Read More
Frequently Asked Questions
9
Effective against cold
1 people found this helpful
Works great for me. I take this daily, but at the first sign of a cold or virus, I increase to 100,000 IU for three days and see a significant difference compared to not taking it!
9
Effective for cold
5 people found this helpful
I have been on a high protein diet for several years and take vitamin A every night, usually 1 tablet. When my throat feels uncomfortable, I take 2 tablets. I also take over 5g of vitamin C, and the signs of a cold usually disappear by the next morning. It is an essential supplement.
9
Strengthened throat
I'm enjoying it without any issues. While excess vitamin A may irritate the skin, I haven't noticed any reactions so far. Taking one tablet daily appears to have strengthened my throat's mucous membrane, and I no longer get colds there.
9
Very effective during cold
11 people found this helpful
Good vitamin A that works very well during colds. It’s important to drink it together with D3 and C.
9
Effective during cold
11 people found this helpful
Okay 💕💯❤️ Vitamin A helps significantly during colds. It's essential to take it with D3 and C.
7.5
Helpful for throat
4 people found this helpful
Dr. Megavita Fujikawa recommends this supplement. It is tasteless, small, and easy to take. For many years, when I have a cold or throat irritation, I take 2 tablets daily, which help protect mucous membranes. However, temporary higher doses are better as they might cause nosebleeds. It's crucial to monitor symptoms and adjust the dosage accordingly.
9
We explored how vitamin A affects our body’s response to cold, specifically looking at its role in transforming white fat into brown fat, a process known as browning. This transformation is significant, as it can help reduce obesity and improve metabolic health.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
References
- Fenzl A, Kulterer OC, Spirk K, Mitulović G, Marculescu R, et al. Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis. Mol Metab. 2020;42:101088. 10.1016/j.molmet.2020.101088
