Last update
5/15/2025

Overview

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Medium or Average
Based on 6 Reviews
6.6
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
7,500 mcg
833%

Top Medical Research Studies

8
Vitamin A toxicity's impact on headaches
We examined a rare case involving a 13-year-old girl who experienced symptoms of headache and visual disturbances due to benign intracranial hypertension (BIH) related to vitamin A toxicity. This condition was characterized by elevated pressure inside her skull, which led to her experiencing severe headaches, photophobia, and vomiting.

After conducting various tests, including magnetic resonance imaging and a lumbar puncture, we confirmed the diagnosis of BIH. Treatment was initiated with acetazolamide, a medication commonly used to reduce intracranial pressure. Although the study primarily focuses on the condition resulting from vitamin A excess, the use of acetazolamide makes it challenging to isolate the effect of vitamin A on headache relief specifically.

What's particularly noteworthy in this case is the significant elevation of serum vitamin A levels, which aligned with her symptoms. Following treatment, this patient showed a remarkable clinical improvement, including a reduction in papilledema during regular eye check-ups. Within just two weeks after starting treatment, she was discharged symptom-free, highlighting how important it is to consider vitamin A levels in children presenting with similar symptoms.

This case serves as a reminder for clinicians regarding the potential consequences of vitamin A toxicity, especially when evaluating children with headaches correlated to papilledema.
Read More
7
Vitamin A shows potential for headaches
We explored a fascinating case of a 36-year-old woman suffering from persistent orthostatic headaches after suffering a seizure. Despite numerous conventional treatments, including five epidural blood patches, she showed little improvement. However, we noticed marked progress when she began vitamin A supplementation.

This case aligns with a discussion of similar cases, where most patients experienced prolonged symptoms without relief. It suggests a link between vitamin A and headache relief, indicating that the underlying issues causing orthostatic headaches may not solely stem from intracranial hypotension. This opens doors for further research into non-traditional treatments.
Read More
5
Limited benefit from vitamin A
We explored a rare condition called orthostatic headache, which lacks evidence of low cerebrospinal fluid pressure. A case followed since 2013 showed that vitamin A supplementation led to some improvement, though it was halted due to side effects from a liver injury in 2017. This patient's headaches then became chronic, requiring alternative treatments. Despite some relief with nerve blocks and medication, the prognosis remains largely unfavorable for many with this condition.
Read More

Most Useful Reviews

7.5
Quality vitamins noted
2 people found this helpful
I started taking this product for chronic headaches related to low cerebrospinal fluid. I advise against using it without a doctor’s supervision, as Vitamin A can build up to toxic levels. The product quality is good, arriving in a sealed bottle. Despite being fish liver derived, it has no fishy aftertaste. I will order this again.
Read More
4
High dosage needed
8 people found this helpful
I take this supplement for my atrophic gastritis and functional dyspepsia. Initially, I took up to 200,000 IU daily, which improved my throat and stomach issues, but led to hair loss. I learned to reduce my intake to 50,000-75,000 IU. It's important to start low and adjust. Interestingly, my sister experienced headaches even with a lower dose of 10,000 IU.
Read More
4
Supplement necessity
8 people found this helpful
While following Dr. Fujikawa's nutrition therapy, I found vitamin A quite effective for my acne. However, taking 50,000 IU daily resulted in headaches and fatigue, so I switched to alternately taking 50,000 IU and 25,000 IU every other day. It's now an essential supplement for me.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
  • All Researches
8
Vitamin A toxicity's impact on headaches
We examined a rare case involving a 13-year-old girl who experienced symptoms of headache and visual disturbances due to benign intracranial hypertension (BIH) related to vitamin A toxicity. This condition was characterized by elevated pressure inside her skull, which led to her experiencing severe headaches, photophobia, and vomiting.

After conducting various tests, including magnetic resonance imaging and a lumbar puncture, we confirmed the diagnosis of BIH. Treatment was initiated with acetazolamide, a medication commonly used to reduce intracranial pressure. Although the study primarily focuses on the condition resulting from vitamin A excess, the use of acetazolamide makes it challenging to isolate the effect of vitamin A on headache relief specifically.

What's particularly noteworthy in this case is the significant elevation of serum vitamin A levels, which aligned with her symptoms. Following treatment, this patient showed a remarkable clinical improvement, including a reduction in papilledema during regular eye check-ups. Within just two weeks after starting treatment, she was discharged symptom-free, highlighting how important it is to consider vitamin A levels in children presenting with similar symptoms.

This case serves as a reminder for clinicians regarding the potential consequences of vitamin A toxicity, especially when evaluating children with headaches correlated to papilledema.
Read More
7
Vitamin A shows potential for headaches
We explored a fascinating case of a 36-year-old woman suffering from persistent orthostatic headaches after suffering a seizure. Despite numerous conventional treatments, including five epidural blood patches, she showed little improvement. However, we noticed marked progress when she began vitamin A supplementation.

This case aligns with a discussion of similar cases, where most patients experienced prolonged symptoms without relief. It suggests a link between vitamin A and headache relief, indicating that the underlying issues causing orthostatic headaches may not solely stem from intracranial hypotension. This opens doors for further research into non-traditional treatments.
Read More
5
Limited benefit from vitamin A
We explored a rare condition called orthostatic headache, which lacks evidence of low cerebrospinal fluid pressure. A case followed since 2013 showed that vitamin A supplementation led to some improvement, though it was halted due to side effects from a liver injury in 2017. This patient's headaches then became chronic, requiring alternative treatments. Despite some relief with nerve blocks and medication, the prognosis remains largely unfavorable for many with this condition.
Read More

User Reviews

USERS' SCORE
Medium or Average
Based on 6 Reviews
6.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Quality vitamins noted
2 people found this helpful
I started taking this product for chronic headaches related to low cerebrospinal fluid. I advise against using it without a doctor’s supervision, as Vitamin A can build up to toxic levels. The product quality is good, arriving in a sealed bottle. Despite being fish liver derived, it has no fishy aftertaste. I will order this again.
Read More
4
High dosage needed
8 people found this helpful
I take this supplement for my atrophic gastritis and functional dyspepsia. Initially, I took up to 200,000 IU daily, which improved my throat and stomach issues, but led to hair loss. I learned to reduce my intake to 50,000-75,000 IU. It's important to start low and adjust. Interestingly, my sister experienced headaches even with a lower dose of 10,000 IU.
Read More
4
Supplement necessity
8 people found this helpful
While following Dr. Fujikawa's nutrition therapy, I found vitamin A quite effective for my acne. However, taking 50,000 IU daily resulted in headaches and fatigue, so I switched to alternately taking 50,000 IU and 25,000 IU every other day. It's now an essential supplement for me.
Read More
0
Side effects noted
2 people found this helpful
Attention should be paid to the dosage, as side effects can be significant. I experienced chest pain, liver pain, headaches, and even shock when taken continually for weeks. It's vital to use it cautiously, perhaps just a week or two daily, or spaced every three days if deficient. Overdoing it can be hazardous.
Read More
2
Monitor intake
Be cautious of excessive intake; while it's good value, being a fat-soluble vitamin, it’s easy to consume too much. Daily usage can lead to headaches, so moderation is key.
Read More

Frequently Asked Questions

4
High dosage needed
8 people found this helpful
I take this supplement for my atrophic gastritis and functional dyspepsia. Initially, I took up to 200,000 IU daily, which improved my throat and stomach issues, but led to hair loss. I learned to reduce my intake to 50,000-75,000 IU. It's important to start low and adjust. Interestingly, my sister experienced headaches even with a lower dose of 10,000 IU.
1
Severe headaches occurred
The results were remarkable; my skin became soft and smooth, but after three months, I began experiencing severe headaches and muscle pain. After doing my research, I learned that the high levels of vitamin A could be responsible, leading me to stop usage. Careful dosage is crucial.
2
Monitor intake
Be cautious of excessive intake; while it's good value, being a fat-soluble vitamin, it’s easy to consume too much. Daily usage can lead to headaches, so moderation is key.
0
Side effects noted
2 people found this helpful
Attention should be paid to the dosage, as side effects can be significant. I experienced chest pain, liver pain, headaches, and even shock when taken continually for weeks. It's vital to use it cautiously, perhaps just a week or two daily, or spaced every three days if deficient. Overdoing it can be hazardous.
4
Supplement necessity
8 people found this helpful
While following Dr. Fujikawa's nutrition therapy, I found vitamin A quite effective for my acne. However, taking 50,000 IU daily resulted in headaches and fatigue, so I switched to alternately taking 50,000 IU and 25,000 IU every other day. It's now an essential supplement for me.
8
Vitamin A toxicity's impact on headaches
We examined a rare case involving a 13-year-old girl who experienced symptoms of headache and visual disturbances due to benign intracranial hypertension (BIH) related to vitamin A toxicity. This condition was characterized by elevated pressure inside her skull, which led to her experiencing severe headaches, photophobia, and vomiting.

After conducting various tests, including magnetic resonance imaging and a lumbar puncture, we confirmed the diagnosis of BIH. Treatment was initiated with acetazolamide, a medication commonly used to reduce intracranial pressure. Although the study primarily focuses on the condition resulting from vitamin A excess, the use of acetazolamide makes it challenging to isolate the effect of vitamin A on headache relief specifically.

What's particularly noteworthy in this case is the significant elevation of serum vitamin A levels, which aligned with her symptoms. Following treatment, this patient showed a remarkable clinical improvement, including a reduction in papilledema during regular eye check-ups. Within just two weeks after starting treatment, she was discharged symptom-free, highlighting how important it is to consider vitamin A levels in children presenting with similar symptoms.

This case serves as a reminder for clinicians regarding the potential consequences of vitamin A toxicity, especially when evaluating children with headaches correlated to papilledema.
7
Vitamin A shows potential for headaches
We explored a fascinating case of a 36-year-old woman suffering from persistent orthostatic headaches after suffering a seizure. Despite numerous conventional treatments, including five epidural blood patches, she showed little improvement. However, we noticed marked progress when she began vitamin A supplementation.

This case aligns with a discussion of similar cases, where most patients experienced prolonged symptoms without relief. It suggests a link between vitamin A and headache relief, indicating that the underlying issues causing orthostatic headaches may not solely stem from intracranial hypotension. This opens doors for further research into non-traditional treatments.

References

  1. Hajaj H, Ghanam A, Zahiri H, Babakhouya A, Rkain M. A Rare Case Report of Benign Intracranial Hypertension Caused by Hypervitaminosis A. Cureus. 2024;16:e59401. 10.7759/cureus.59401
  2. Bonifácio GV, Gil-Gouveia R. Update on "Treatment of orthostatic headache without intracranial hypotension: A case report" - nine years later. Cephalalgia. 2022;42:273. 10.1177/03331024211038656
  3. Gil-Gouveia R. Treatment of orthostatic headache without intracranial hypotension: a case report. Cephalalgia. 2013;33:948. 10.1177/0333102413482192
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