Overview
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
7,500 mcg
833%
Top Medical Research Studies
9
We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.
Read More
9
We examined how retinoic acid (a form of vitamin A) could promote the repair of heart tissue after injury. Through the use of self-assembling peptides to deliver retinoic acid, we found that it effectively increased the proliferation of heart cells in rats. This treatment also boosted the expression of key genes associated with heart regeneration and improved heart function within four weeks. Overall, our findings suggest that retinoic acid might be a promising strategy to enhance the recovery of damaged heart tissue.
Read More
7
We explored how vitamin A influences heart health in mice with diet-induced obesity. Through a study comparing genetically altered mice with vitamin A deficiencies to normal mice fed a vitamin A-sufficient diet, we found that, despite vitamin A deficiency, the heart's structure, function, and energy production capabilities remained intact after 20 weeks.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Read More
Most Useful Reviews
9
Effective recovery
An excellent choice. The main thing is to overcome the disease, and this has greatly helped in my recovery.
Read More
7.5
Minimal side effects
40 people found this helpful
It aids in repairing and maintaining mucous membranes, making it effective for rough stomachs and throats. The talk about excess Vitamin A often stems from misconceptions. The acceptable amount can vary significantly among individuals, but it’s not a potent drug that leads to hospitalisation after a single tablet. If you're cautious about overdosing, you may opt for one tablet every three days. Personally, I have no issues taking it daily potentially due to my family history of cancer. If taken long-term and feeling unwell, it’s wise to take a break occasionally.
Read More
7.5
Positive impact
4 people found this helpful
I’m giving this product to my partner who has had a severe heart attack, and I truly believe it’s aiding him. His skin tone is good, and his heart seems to be doing well.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
- All Researches
9
We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.
Read More
9
We examined how retinoic acid (a form of vitamin A) could promote the repair of heart tissue after injury. Through the use of self-assembling peptides to deliver retinoic acid, we found that it effectively increased the proliferation of heart cells in rats. This treatment also boosted the expression of key genes associated with heart regeneration and improved heart function within four weeks. Overall, our findings suggest that retinoic acid might be a promising strategy to enhance the recovery of damaged heart tissue.
Read More
8
We examined the connection between serum retinol levels, a marker for vitamin A, and long-term mortality over 30 years. Our analysis involved nearly 29,000 men and revealed that those with higher retinol levels had a 17-32% lower risk of dying from heart disease and other causes compared to those with lower levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
Read More
7
We explored how vitamin A influences heart health in mice with diet-induced obesity. Through a study comparing genetically altered mice with vitamin A deficiencies to normal mice fed a vitamin A-sufficient diet, we found that, despite vitamin A deficiency, the heart's structure, function, and energy production capabilities remained intact after 20 weeks.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Read More
4
We analyzed data from 7,341 adults aged 65 and older to see how various nutrients affect heart disease.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective recovery
An excellent choice. The main thing is to overcome the disease, and this has greatly helped in my recovery.
Read More
7.5
Minimal side effects
40 people found this helpful
It aids in repairing and maintaining mucous membranes, making it effective for rough stomachs and throats. The talk about excess Vitamin A often stems from misconceptions. The acceptable amount can vary significantly among individuals, but it’s not a potent drug that leads to hospitalisation after a single tablet. If you're cautious about overdosing, you may opt for one tablet every three days. Personally, I have no issues taking it daily potentially due to my family history of cancer. If taken long-term and feeling unwell, it’s wise to take a break occasionally.
Read More
7.5
Positive impact
4 people found this helpful
I’m giving this product to my partner who has had a severe heart attack, and I truly believe it’s aiding him. His skin tone is good, and his heart seems to be doing well.
Read More
6
Prevention and care
3 people found this helpful
Excellent! I find it beneficial for disease prevention and improving my constitution. However, if intake exceeds individual needs, skin symptoms may arise, so caution is necessary. In my case, I reduced the intake to every other day when I experienced skin issues, which subsequently improved.
Read More
9
Immunity boost
2 people found this helpful
This supplement improved my immunity and remarkably cured my chronic cough, which I had struggled with for ages. I recommend it for those who often fall ill; it strengthens the immune system without any downsides.
Read More
Frequently Asked Questions
7.5
Positive impact
4 people found this helpful
I’m giving this product to my partner who has had a severe heart attack, and I truly believe it’s aiding him. His skin tone is good, and his heart seems to be doing well.
6
Dry eyes improved
Taking two tablets weekly has been beneficial, especially as I initially used retinol for dry eye care and noticed improvements. Previously needing eye drops consistently, I believe my heart health has now improved too.
7.5
Essential vitamin
1 people found this helpful
It’s an essential vitamin for maintaining healthy eyes, heart, and blood vessels, promoting youthful skin and enhancing blood circulation. The large size, reasonable price, and excellent quality make it highly recommendable.
9
Immunity boost
2 people found this helpful
This supplement improved my immunity and remarkably cured my chronic cough, which I had struggled with for ages. I recommend it for those who often fall ill; it strengthens the immune system without any downsides.
6
Prevention and care
3 people found this helpful
Excellent! I find it beneficial for disease prevention and improving my constitution. However, if intake exceeds individual needs, skin symptoms may arise, so caution is necessary. In my case, I reduced the intake to every other day when I experienced skin issues, which subsequently improved.
7.5
Minimal side effects
40 people found this helpful
It aids in repairing and maintaining mucous membranes, making it effective for rough stomachs and throats. The talk about excess Vitamin A often stems from misconceptions. The acceptable amount can vary significantly among individuals, but it’s not a potent drug that leads to hospitalisation after a single tablet. If you're cautious about overdosing, you may opt for one tablet every three days. Personally, I have no issues taking it daily potentially due to my family history of cancer. If taken long-term and feeling unwell, it’s wise to take a break occasionally.
6
Immune booster
1 people found this helpful
Vitamin A is excellent for heart, kidney, lung, skin, eyes, and bone health. It's an immune booster and anti-aging ally. I take this three times a week for maintenance, with brands like California Gold being my preferred choice for supplements. Thanks to iHerb!
4
We analyzed data from 7,341 adults aged 65 and older to see how various nutrients affect heart disease.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
9
We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.
8
We examined the connection between serum retinol levels, a marker for vitamin A, and long-term mortality over 30 years. Our analysis involved nearly 29,000 men and revealed that those with higher retinol levels had a 17-32% lower risk of dying from heart disease and other causes compared to those with lower levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
7
We explored how vitamin A influences heart health in mice with diet-induced obesity. Through a study comparing genetically altered mice with vitamin A deficiencies to normal mice fed a vitamin A-sufficient diet, we found that, despite vitamin A deficiency, the heart's structure, function, and energy production capabilities remained intact after 20 weeks.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
2
We explored the potential impact of various nutrition-related factors, including vitamin B12, vitamin E, and retinol, on atrial fibrillation (AF) risk. Using a robust Mendelian randomization approach involving data from over 60,000 cases and almost a million controls, we found no significant causal effects from any of these vitamins or minerals. Our analysis remains consistent even when subjected to different scrutiny methods. This study suggests that circulating levels of these nutrients do not play a role in the development of AF.
References
- Li W, Liu S, Meng X, Liu H. A nutrient wide association study of cardiovascular disease prevalence in older adults from NHANES 2007 to 2018. Sci Rep. 2025;15:12710. doi:10.1038/s41598-025-97143-8
- Rettkowski J, Romero-Mulero MC, Singh I, Wadle C, Wrobel J, et al. Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study. Nat Cell Biol. 2025;27:591. doi:10.1038/s41556-025-01639-4
- Kawai S, Pak K, Iwamoto S, Kawakami C, Inuzuka R, et al. Association Between Maternal Factors in Early Pregnancy and Congenital Heart Defects in Offspring: The Japan Environment and Children's Study. J Am Heart Assoc. 2023;12:e029268. doi:10.1161/JAHA.122.029268
- Tan YZ, Shen HR, Wang YL, Wang QL, Wu XP, et al. Retinoic acid released from self-assembling peptide activates cardiomyocyte proliferation and enhances repair of infarcted myocardium. Exp Cell Res. 2023;422:113440. doi:10.1016/j.yexcr.2022.113440
- Naasner L, Froese N, Hofmann W, Galuppo P, Werlein C, et al. Vitamin A preserves cardiac energetic gene expression in a murine model of diet-induced obesity. Am J Physiol Heart Circ Physiol. 2022;323:H1352. doi:10.1152/ajpheart.00514.2022
- Huang J. Circulating Concentrations of Nutrition-Related Factors Are Not Causally Associated With Atrial Fibrillation: A Mendelian Randomization Study. J Cardiovasc Pharmacol. 2022;80:210. doi:10.1097/FJC.0000000000001263
- Huang J, Weinstein SJ, Yu K, Männistö S, Albanes D. Association between serum retinol and overall and cause-specific mortality in a 30-year prospective cohort study. Nat Commun. 2021;12:6418. doi:10.1038/s41467-021-26639-4
