Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
USERS' SCORE
Good
Based on 14 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
7,500 mcg
833%
Top Medical Research Studies
9.5
We focused on the protective effects of vitamin A on stress-induced gastric lesions in piglets after experiencing hemorrhagic shock. In our study, piglets were subjected to low blood pressure and then treated with different doses of vitamin A. Remarkably, those receiving vitamin A showed no signs of gastric lesions.
This suggests that vitamin A plays a significant role in safeguarding the gastric lining against stress-related damage during critical conditions.
Overall, our findings highlight the potential benefits of vitamin A in both veterinary and human medicine for ulcer prevention under stress.
This suggests that vitamin A plays a significant role in safeguarding the gastric lining against stress-related damage during critical conditions.
Overall, our findings highlight the potential benefits of vitamin A in both veterinary and human medicine for ulcer prevention under stress.
Read More
9
We explored the effects of dietary vitamin A on preventing duodenal ulcers in rats induced by cysteamine-HCl. In our study, we compared two groups of rats—one receiving a standard diet and the other supplemented with vitamin A.
After exposing them to cysteamine-HCl, we observed that only 32% of the vitamin A group developed ulcers, compared to 74% in the control group. This shows a significant protective effect of vitamin A on ulcer formation, although it did not influence gastric acid production.
Overall, our findings suggest vitamin A supplementation could be beneficial in reducing duodenal ulcer risk in this experimental model.
After exposing them to cysteamine-HCl, we observed that only 32% of the vitamin A group developed ulcers, compared to 74% in the control group. This shows a significant protective effect of vitamin A on ulcer formation, although it did not influence gastric acid production.
Overall, our findings suggest vitamin A supplementation could be beneficial in reducing duodenal ulcer risk in this experimental model.
Read More
8
Beta-carotene shows ulcer benefits
We explored the effects of daily beta-carotene treatment on patients with duodenal ulcers and erosive gastritis. After administering 18 mg of beta-carotene in an oil solution, we observed a threefold increase in its blood serum levels.
Although the concentration of retinol remained unchanged, indicating no harmful effects, the treatment showed promising results. It improved the antioxidative system, reduced pain, helped heal ulcers, and led to the healing of erosions in the gastric mucosa.
Although the concentration of retinol remained unchanged, indicating no harmful effects, the treatment showed promising results. It improved the antioxidative system, reduced pain, helped heal ulcers, and led to the healing of erosions in the gastric mucosa.
Read More
Most Useful Reviews
9
Improvement observed
56 people found this helpful
The required dosage of vitamin A varies significantly between individuals, particularly for those with dry eyes, asthma, gastrointestinal issues, or a history of cancer. Due to my low protein intake, I've gradually increased my dosage to 100,000 units over a year. Remarkably, my persistent gastritis, unresolved for over ten years, has cleared, eliminating the need for medication.
Read More
7.5
Reduced ulcers significantly
7 people found this helpful
My family has been notably deficient in vitamin A. I've adjusted my intake to 25,000 IU daily, hoping it will benefit my severe myopia and dry eyes. Interestingly, my long-standing exfoliative cheilitis improved, which I struggled with for years. Unlike other vitamins, vitamin A noticeably reduced the roughness of my lips, leading to better skin condition.
Read More
7.5
Ulcer improvement noted
5 people found this helpful
I previously took three vitamin A tablets daily but am now pleased to manage with just one. This lower dosage, combined with a variety of other vitamins, has resulted in marked improvement in my mouth ulcers and eczema. Surprisingly, I haven't experienced hay fever this year, and I feel I've adequately replenished my body’s nutrient needs.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
- All Researches
9.5
We focused on the protective effects of vitamin A on stress-induced gastric lesions in piglets after experiencing hemorrhagic shock. In our study, piglets were subjected to low blood pressure and then treated with different doses of vitamin A. Remarkably, those receiving vitamin A showed no signs of gastric lesions.
This suggests that vitamin A plays a significant role in safeguarding the gastric lining against stress-related damage during critical conditions.
Overall, our findings highlight the potential benefits of vitamin A in both veterinary and human medicine for ulcer prevention under stress.
This suggests that vitamin A plays a significant role in safeguarding the gastric lining against stress-related damage during critical conditions.
Overall, our findings highlight the potential benefits of vitamin A in both veterinary and human medicine for ulcer prevention under stress.
Read More
9
We explored the effects of dietary vitamin A on preventing duodenal ulcers in rats induced by cysteamine-HCl. In our study, we compared two groups of rats—one receiving a standard diet and the other supplemented with vitamin A.
After exposing them to cysteamine-HCl, we observed that only 32% of the vitamin A group developed ulcers, compared to 74% in the control group. This shows a significant protective effect of vitamin A on ulcer formation, although it did not influence gastric acid production.
Overall, our findings suggest vitamin A supplementation could be beneficial in reducing duodenal ulcer risk in this experimental model.
After exposing them to cysteamine-HCl, we observed that only 32% of the vitamin A group developed ulcers, compared to 74% in the control group. This shows a significant protective effect of vitamin A on ulcer formation, although it did not influence gastric acid production.
Overall, our findings suggest vitamin A supplementation could be beneficial in reducing duodenal ulcer risk in this experimental model.
Read More
9
In our investigation, we examined how vitamin A and beta-carotene impact gastric ulcers in rats. By administering these compounds before inducing gastric damage with ethanol or hydrochloric acid, we observed a notable reduction in both the number and severity of ulcers.
This suggests that both vitamin A and beta-carotene help protect the stomach lining. However, while they effectively prevent ulcers, they don't fully restore the activity of a crucial enzyme involved in gastric defense. Overall, we found that these vitamins play a key protective role, primarily due to their ability to act as antioxidants.
This suggests that both vitamin A and beta-carotene help protect the stomach lining. However, while they effectively prevent ulcers, they don't fully restore the activity of a crucial enzyme involved in gastric defense. Overall, we found that these vitamins play a key protective role, primarily due to their ability to act as antioxidants.
Read More
9
We examined a unique case of lip ulcers linked to the intravenous use of zoledronic acid (ZA) in a patient undergoing treatment for metastatic breast cancer. Despite managing the patient's anemia and an E. coli infection, the ulcers persisted until ZA was discontinued.
After halting the medication, the ulcers healed within three months with a treatment plan that included systemic antibiotics and vitamins A and E. However, upon resuming ZA, recurrence occurred, but follow-up treatment kept the patient clear of lesions for 18 months.
This case highlights how vitamin A can aid in the healing of severe oral mucosal ulcers related to bisphosphonate therapy.
After halting the medication, the ulcers healed within three months with a treatment plan that included systemic antibiotics and vitamins A and E. However, upon resuming ZA, recurrence occurred, but follow-up treatment kept the patient clear of lesions for 18 months.
This case highlights how vitamin A can aid in the healing of severe oral mucosal ulcers related to bisphosphonate therapy.
Read More
8
Vitamin A protects against ARA-C damage
We investigated whether vitamin A could shield against intestinal damage caused by ARA-C, a common leukemia treatment known for its side effects like mucosal lesions. Mice in our study were divided into several groups, some receiving vitamin A alongside ARA-C.
Our results revealed that mice treated with vitamin A showed significantly improved gut health compared to those who did not receive it. They exhibited better mucosal integrity and less tissue damage, suggesting that vitamin A can indeed play a protective role against the harmful effects of ARA-C.
Our results revealed that mice treated with vitamin A showed significantly improved gut health compared to those who did not receive it. They exhibited better mucosal integrity and less tissue damage, suggesting that vitamin A can indeed play a protective role against the harmful effects of ARA-C.
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User Reviews
USERS' SCORE
Good
Based on 14 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improvement observed
56 people found this helpful
The required dosage of vitamin A varies significantly between individuals, particularly for those with dry eyes, asthma, gastrointestinal issues, or a history of cancer. Due to my low protein intake, I've gradually increased my dosage to 100,000 units over a year. Remarkably, my persistent gastritis, unresolved for over ten years, has cleared, eliminating the need for medication.
Read More
7.5
Reduced ulcers significantly
7 people found this helpful
My family has been notably deficient in vitamin A. I've adjusted my intake to 25,000 IU daily, hoping it will benefit my severe myopia and dry eyes. Interestingly, my long-standing exfoliative cheilitis improved, which I struggled with for years. Unlike other vitamins, vitamin A noticeably reduced the roughness of my lips, leading to better skin condition.
Read More
7.5
Ulcer improvement noted
5 people found this helpful
I previously took three vitamin A tablets daily but am now pleased to manage with just one. This lower dosage, combined with a variety of other vitamins, has resulted in marked improvement in my mouth ulcers and eczema. Surprisingly, I haven't experienced hay fever this year, and I feel I've adequately replenished my body’s nutrient needs.
Read More
10
Quick ulcer recovery
3 people found this helpful
I've noticed fantastic results with my eye strain and mouth ulcers since starting this vitamin A supplement. My eye discomfort from excessive smartphone use has greatly diminished, and my lip ulcers healed remarkably fast. After a brief hiatus from the supplement, I experienced headaches again, highlighting its effectiveness. My skin has also improved significantly.
Read More
9
Preventive effects observed
2 people found this helpful
I was frequently plagued by mouth ulcers, but since taking vitamin A, I’ve found a significant decrease in their occurrence. Skipping doses makes me anxious about ulcer signs returning, reinforcing its preventative capabilities for me.
Read More
Frequently Asked Questions
9
Ulcers less frequent
1 people found this helpful
Previously, I was susceptible to mouth ulcers and took vitamin B for relief. Since adding vitamin A, I’ve noticed a significant decrease in their occurrence.
9
Immediate effect
It's easy to drink. For me, it works immediately on my mouth ulcers!
9
Preventive effects observed
2 people found this helpful
I was frequently plagued by mouth ulcers, but since taking vitamin A, I’ve found a significant decrease in their occurrence. Skipping doses makes me anxious about ulcer signs returning, reinforcing its preventative capabilities for me.
10
Quick ulcer recovery
3 people found this helpful
I've noticed fantastic results with my eye strain and mouth ulcers since starting this vitamin A supplement. My eye discomfort from excessive smartphone use has greatly diminished, and my lip ulcers healed remarkably fast. After a brief hiatus from the supplement, I experienced headaches again, highlighting its effectiveness. My skin has also improved significantly.
7.5
Reduced ulcers significantly
7 people found this helpful
My family has been notably deficient in vitamin A. I've adjusted my intake to 25,000 IU daily, hoping it will benefit my severe myopia and dry eyes. Interestingly, my long-standing exfoliative cheilitis improved, which I struggled with for years. Unlike other vitamins, vitamin A noticeably reduced the roughness of my lips, leading to better skin condition.
8
Ulcers and dryness decreased
1 people found this helpful
Taking one vitamin A tablet daily has eliminated my mouth ulcers and resolved the roughness of my lips. The value for money is also commendable.
9
Improvement observed
56 people found this helpful
The required dosage of vitamin A varies significantly between individuals, particularly for those with dry eyes, asthma, gastrointestinal issues, or a history of cancer. Due to my low protein intake, I've gradually increased my dosage to 100,000 units over a year. Remarkably, my persistent gastritis, unresolved for over ten years, has cleared, eliminating the need for medication.
7.5
Ulcer improvement noted
5 people found this helpful
I previously took three vitamin A tablets daily but am now pleased to manage with just one. This lower dosage, combined with a variety of other vitamins, has resulted in marked improvement in my mouth ulcers and eczema. Surprisingly, I haven't experienced hay fever this year, and I feel I've adequately replenished my body’s nutrient needs.
9
Mandatory intake for prevention
I take vitamin D, making the intake of vitamin A essential for preventing mouth ulcers.
6
Fewer mouth ulcers
Since it is a fat-soluble vitamin, I take it about 2-3 times a week to avoid overdoing it. I feel that I have fewer mouth ulcers.
9
Cured multiple conditions
2 people found this helpful
Through nutritional therapy endorsed by Dr. Tokumi Fujikawa, I learned that vitamin A deficiency could be more harmful than excess. Taking a large dose during episodes of sore throat or ulcers alleviates discomfort swiftly. The quality of this supplement is commendable. It's particularly beneficial for anyone battling chronic illnesses, including cancer.
5
We reviewed the evidence on how diet influences duodenal ulcers (DU), focusing on a high-fibre diet as a potential protective factor.
Our findings suggest that increasing dietary fibre—especially from fruits and vegetables—can significantly reduce the risk of developing DU.
Furthermore, vitamin A intake may also lower the risk. However, there’s limited evidence that other factors like fat, protein, or alcohol consumption affect DU risk.
Our findings suggest that increasing dietary fibre—especially from fruits and vegetables—can significantly reduce the risk of developing DU.
Furthermore, vitamin A intake may also lower the risk. However, there’s limited evidence that other factors like fat, protein, or alcohol consumption affect DU risk.
7
We investigated the effects of a vitamin treatment, Aevit, alongside standard antiulcer therapy in patients with duodenal ulcers. Our findings indicate that Aevit, combined with piracetam, leads to quicker improvements in both clinical and endoscopic signs of ulcers.
Additionally, we noted enhancements in psychological responses and physical endurance. Overall, the results suggest that this vitamin treatment could be beneficial in managing duodenal ulcer recurrences effectively.
Additionally, we noted enhancements in psychological responses and physical endurance. Overall, the results suggest that this vitamin treatment could be beneficial in managing duodenal ulcer recurrences effectively.
9
We explored the effects of dietary vitamin A on preventing duodenal ulcers in rats induced by cysteamine-HCl. In our study, we compared two groups of rats—one receiving a standard diet and the other supplemented with vitamin A.
After exposing them to cysteamine-HCl, we observed that only 32% of the vitamin A group developed ulcers, compared to 74% in the control group. This shows a significant protective effect of vitamin A on ulcer formation, although it did not influence gastric acid production.
Overall, our findings suggest vitamin A supplementation could be beneficial in reducing duodenal ulcer risk in this experimental model.
After exposing them to cysteamine-HCl, we observed that only 32% of the vitamin A group developed ulcers, compared to 74% in the control group. This shows a significant protective effect of vitamin A on ulcer formation, although it did not influence gastric acid production.
Overall, our findings suggest vitamin A supplementation could be beneficial in reducing duodenal ulcer risk in this experimental model.
8
Vitamin A shows modest ulcer benefits
We compared the healing effects of vitamin A, De-Nol, and sucralfate with pirenzepine in patients suffering from chronic gastric ulcers. Over four weeks, 100 patients received different treatments and we monitored their progress through endoscopy.
While ulcer size decreased across all groups, De-Nol showed the most significant reduction. Interestingly, vitamin A demonstrated notably positive effects on ulcer healing during the second week, although its overall impact was less pronounced than that of De-Nol.
Thus, while vitamin A has some benefits, De-Nol appears to be the most effective for healing chronic gastric ulcers.
While ulcer size decreased across all groups, De-Nol showed the most significant reduction. Interestingly, vitamin A demonstrated notably positive effects on ulcer healing during the second week, although its overall impact was less pronounced than that of De-Nol.
Thus, while vitamin A has some benefits, De-Nol appears to be the most effective for healing chronic gastric ulcers.
References
- Elli M, Aydin O, Bilge S, Bozkurt A, Dagdemir A, et al. Protective effect of vitamin A on ARA-C induced intestinal damage in mice. Tumori. 2009;95:87.
- Ryan-Harshman M, Aldoori W. How diet and lifestyle affect duodenal ulcers. Review of the evidence. Can Fam Physician. 2004;50:727.
- Pimenov LT, Balobanov VIu, Pushina LN, Shemiakina TV. [The clinico-endoscopic, psychological and physical characteristics of duodenal peptic ulcer patients using piracetam and aevit]. Ter Arkh. 1997;69:10.
- Aldoori WH, Giovannucci EL, Stampfer MJ, Rimm EB, Wing AL, et al. Prospective study of diet and the risk of duodenal ulcer in men. Am J Epidemiol. 1997;145:42.
- Stanislavchuk NA, Pentiuk AA, Vovk OG, Ostapchuk EI. [The influence of retinol, tocopherol and cimetidine on the ulcerogenic effect of Orthofen, indomethacin and naproxen]. Eksp Klin Farmakol. 1995;58:33.
- Mózsik G, Hunyady B, Garamszegi M, Németh A, Pakodi F, et al. Dynamism of cytoprotective and antisecretory drugs in patients with unhealed gastric and duodenal ulcers. J Gastroenterol Hepatol. 1994;9 Suppl 1:S88.
- Spirichev VB, Levachev MM, Rymarenko TV, Iakushina LM, Kharitonchik LA, et al. [The effect of administration of beta-carotene in an oil solution on its blood serum level and antioxidant status of patients with duodenal ulcer and erosive gastritis]. Vopr Med Khim. 1992;38:44.
- Király A, Sütö G, Vincze A, Tóth G, Matus Z, et al. Correlation between the cytoprotective effect of beta-carotene and its gastric mucosal level in indomethacin (IND) treated rats with or without acute surgical vagotomy. Acta Physiol Hung. 1992;80:213.
- Granov AM, Aiskhanov SK, Nikolaev LI, Smirnova NA. [Clinico-endoscopic evaluation of the effectiveness of the treatment of uncomplicated gastroduodenal ulcers after local administration of solcoseryl and aevit]. Vestn Khir Im I I Grek. 1989;144:12.
- Mahmood T, Tenenbaum S, Niu XT, Levenson SM, Seifter E, et al. Prevention of duodenal ulcer formation in the rat by dietary vitamin A supplementation. JPEN J Parenter Enteral Nutr. 1986;10:74.
- Mózsik G, Jávor T, Tóth G, Zsoldos T, Tigyi A. Interrelationships between the gastric cytoprotective effects of vitamin A and beta-carotene and the gastric mucosal superoxide dismutase activity in rats. Acta Physiol Hung. 1984;64:315.
- Patty I, Tárnok F, Simon L, Jávor T, Deák G, et al. A comparative dynamic study of the effectiveness of gastric cytoprotection by vitamin A, De-Nol, sucralfate and ulcer healing by pirenzepine in patients with chronic gastric ulcer (a multiclinical and randomized study). Acta Physiol Hung. 1984;64:379.
- Patty I, Benedek S, Deák G, Jávor T, Kenéz P, et al. Cytoprotective effect of vitamin A and its clinical importance in the treatment of patients with chronic gastric ulcer. Int J Tissue React. 1983;5:301.
- von Gerstenbergk L, Büsing M, Seufert RM, Doertenbach J, Hottenrott C. [Lose-dose treatment with vitamin A in prevention of stress ulcer in swine]. Langenbecks Arch Chir. 1976;Suppl:224.
- Schumpelick V, Farthmann E. [Study on the protective effect of vitamin A on stress ulcer of the rat (author's transl)]. Arzneimittelforschung. 1976;26:386.
- Kivilaakso E, Kalima TV, Lempinen M. Modification of procine stress ulceration by methylprednisolone, vitaminA and methysergide treatment. Eur Surg Res. 1976;8:281.
- Andreadis D, Mauroudis S, Poulopoulos A, Markopoulos A, Epivatianos A. Lip ulceration associated with intravenous administration of zoledronic acid: report of a case. Head Neck Pathol. 2012;6:275. doi:10.1007/s12105-011-0313-8
- Lischer CJ, Dietrich-Hunkeler A, Geyer H, Schulze J, Ossent P. [Healing process of uncomplicated sole ulcers in dairy cows kept in tie stalls: clinical description and blood chemical investigations]. Schweiz Arch Tierheilkd. 2001;143:125.
