Overview

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Good
Based on 11 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
L-Glutamine (Free-Form)
1 g (1,000 mg)
**

Top Medical Research Studies

We explored how L-glutamine affects liver health in ob/ob mice, specifically looking at its antioxidant and anti-inflammatory properties. Over 40 days, mice received either L-alanyl-L-glutamine or free L-glutamine, while control mice drank just water.

Our findings showed that the L-alanyl-L-glutamine group experienced improved insulin sensitivity and reduced liver fat. Although free L-glutamine raised muscle glutamine levels, it had less impact on overall insulin resistance. Ultimately, boosting glutamine levels helped mitigate oxidative stress and inflammation linked to obesity.
Read More
4
Potential muscle mass maintenance
We looked into the effectiveness of a beverage combining β-hydroxy-β-methyl butyrate, l-arginine, and l-glutamine, along with locomotion training, for patients undergoing treatment for unresectable hepatocellular carcinoma using lenvatinib.

In a pilot study involving 20 patients, we found that while the combination drink didn’t reduce hand-foot-skin reactions—one of the common side effects—it may help in preserving muscle mass. Thus, further research with a larger group is needed to confirm these results.
Read More

Most Useful Reviews

9
Detox support
9 people found this helpful
I use it with glycine, cysteine, NAC, and vitamin C to produce glutathione, acting as an antioxidant to cleanse the liver and body of toxins. If you find this review helpful, please click the Like button.
Read More
9
Reflux improvement
7 people found this helpful
This product has tremendously helped my terrible reflux and oesophagitis. I had taken NEXIUM but found it caused various other issues, so I stopped. The burning was severe initially, but taking Now Foods L-Glutamine a couple of times a day, just before or after meals, has allowed me to rarely experience reflux now. A fantastic product with super fast delivery thanks to iHerb and DHL.
Read More
7.5
Eases symptoms
6 people found this helpful
Great! I have leaky gut syndrome, which gives me all sorts of symptoms, including food allergies. This eases them up.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
  • All Researches
We explored how L-glutamine affects liver health in ob/ob mice, specifically looking at its antioxidant and anti-inflammatory properties. Over 40 days, mice received either L-alanyl-L-glutamine or free L-glutamine, while control mice drank just water.

Our findings showed that the L-alanyl-L-glutamine group experienced improved insulin sensitivity and reduced liver fat. Although free L-glutamine raised muscle glutamine levels, it had less impact on overall insulin resistance. Ultimately, boosting glutamine levels helped mitigate oxidative stress and inflammation linked to obesity.
Read More
4
Potential muscle mass maintenance
We looked into the effectiveness of a beverage combining β-hydroxy-β-methyl butyrate, l-arginine, and l-glutamine, along with locomotion training, for patients undergoing treatment for unresectable hepatocellular carcinoma using lenvatinib.

In a pilot study involving 20 patients, we found that while the combination drink didn’t reduce hand-foot-skin reactions—one of the common side effects—it may help in preserving muscle mass. Thus, further research with a larger group is needed to confirm these results.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Detox support
9 people found this helpful
I use it with glycine, cysteine, NAC, and vitamin C to produce glutathione, acting as an antioxidant to cleanse the liver and body of toxins. If you find this review helpful, please click the Like button.
Read More
9
Reflux improvement
7 people found this helpful
This product has tremendously helped my terrible reflux and oesophagitis. I had taken NEXIUM but found it caused various other issues, so I stopped. The burning was severe initially, but taking Now Foods L-Glutamine a couple of times a day, just before or after meals, has allowed me to rarely experience reflux now. A fantastic product with super fast delivery thanks to iHerb and DHL.
Read More
7.5
Eases symptoms
6 people found this helpful
Great! I have leaky gut syndrome, which gives me all sorts of symptoms, including food allergies. This eases them up.
Read More
7.5
Healing support
5 people found this helpful
This product is reputed to aid intestinal healing, particularly for individuals with Crohn's disease, which is why I use it. Combining it with wormwood, ashwagandha, and Boswellia has significantly improved my health. I also incorporate Reishi in the evening, panax ginseng in the afternoon, and rhodiola in the morning. Maintaining a healthy diet and mindset, along with these supplements, fosters overall well-being.
Read More
6
Boosts immunity and recovery
3 people found this helpful
Glutamine, when combined with taurine, enhances recovery and immunity. As protein is broken down into glutamine, excess intake can improve muscle resilience and intestinal health. Taurine also supports liver function and fatigue recovery. For optimal recovery, it's advised to combine both supplements, particularly after intense exercises.
Read More

Frequently Asked Questions

7.5
Important for bowel health
5 people found this helpful
Living with Crohn's disease, I’ve avoided immunosuppressive treatments and relied heavily on supplements to reclaim a normal life. Glutamine is crucial for my bowel health, and I was pleasantly surprised by the attractive packaging. I began taking it today, hoping for a swift recovery.
7.5
Liver restoration
This dosage has been beneficial for restoring my intestines and is also good for the liver, as I saw recommended.
9
Reflux improvement
7 people found this helpful
This product has tremendously helped my terrible reflux and oesophagitis. I had taken NEXIUM but found it caused various other issues, so I stopped. The burning was severe initially, but taking Now Foods L-Glutamine a couple of times a day, just before or after meals, has allowed me to rarely experience reflux now. A fantastic product with super fast delivery thanks to iHerb and DHL.
7.5
Eases symptoms
6 people found this helpful
Great! I have leaky gut syndrome, which gives me all sorts of symptoms, including food allergies. This eases them up.
7.5
Healing support
5 people found this helpful
This product is reputed to aid intestinal healing, particularly for individuals with Crohn's disease, which is why I use it. Combining it with wormwood, ashwagandha, and Boswellia has significantly improved my health. I also incorporate Reishi in the evening, panax ginseng in the afternoon, and rhodiola in the morning. Maintaining a healthy diet and mindset, along with these supplements, fosters overall well-being.
7.5
Improved bowel movements
I started taking glutamine after learning it could enhance my gut health. As I age, my bowel movements have slowed, causing discomfort. Since beginning this supplement, I've noticed improvement in my digestive regularity. The capsules are sizable but manageable. I typically take two at night and one in the morning, which has made a positive difference, and I appreciate the quality of the natural ingredients.
7.5
Eases outbreaks
This has helped to ease outbreaks of my leaky gut syndrome significantly.
9
Detox support
9 people found this helpful
I use it with glycine, cysteine, NAC, and vitamin C to produce glutathione, acting as an antioxidant to cleanse the liver and body of toxins. If you find this review helpful, please click the Like button.
6
Boosts immunity and recovery
3 people found this helpful
Glutamine, when combined with taurine, enhances recovery and immunity. As protein is broken down into glutamine, excess intake can improve muscle resilience and intestinal health. Taurine also supports liver function and fatigue recovery. For optimal recovery, it's advised to combine both supplements, particularly after intense exercises.
We explored how L-glutamine affects liver health in ob/ob mice, specifically looking at its antioxidant and anti-inflammatory properties. Over 40 days, mice received either L-alanyl-L-glutamine or free L-glutamine, while control mice drank just water.

Our findings showed that the L-alanyl-L-glutamine group experienced improved insulin sensitivity and reduced liver fat. Although free L-glutamine raised muscle glutamine levels, it had less impact on overall insulin resistance. Ultimately, boosting glutamine levels helped mitigate oxidative stress and inflammation linked to obesity.
4
Potential muscle mass maintenance
We looked into the effectiveness of a beverage combining β-hydroxy-β-methyl butyrate, l-arginine, and l-glutamine, along with locomotion training, for patients undergoing treatment for unresectable hepatocellular carcinoma using lenvatinib.

In a pilot study involving 20 patients, we found that while the combination drink didn’t reduce hand-foot-skin reactions—one of the common side effects—it may help in preserving muscle mass. Thus, further research with a larger group is needed to confirm these results.

References

  1. Leite JSM, Vilas-Boas EA, Takahashi HK, Munhoz AC, Araújo LCC, et al. Liver lipid metabolism, oxidative stress, and inflammation in glutamine-supplemented ob/ob mice. J Nutr Biochem. 2025;138:109842. 10.1016/j.jnutbio.2025.109842
  2. Naganuma A, Makita F, Sugimoto R, Kikuchi M, Furuta K, et al. An open-label, randomized, controlled trial on the benefit of β-hydroxy-β-methyl butyrate, l-arginine, l-glutamine combination beverages and locomotion training as supportive care for the treatment of unresectable hepatocellular carcinoma using lenvatinib: A pilot study (HELLO study). Clin Nutr ESPEN. 2025;65:357. 10.1016/j.clnesp.2024.12.005
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