Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.5
USERS' SCORE
Good
Based on 4 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Taurine (Free-Form)
1 g (1,000 mg)
*
Top Medical Research Studies
9
We explored how taurine, an amino acid that might seem simple, plays a significant role in helping people with allergic rhinitis (AR). Allergic rhinitis, a common condition, can cause a lot of discomfort, and while various treatments are available, many come with unwanted side effects. Our focus was to see if taurine could be an effective and safer alternative for managing AR symptoms.
In our investigation, we looked at blood samples from individuals, both healthy donors and AR patients, to determine the effects of taurine on T regulatory cells, or Tregs, which are crucial for regulating immune responses. We also examined how taurine might influence specific cytokines involved in allergic reactions and help restore normal nasal function. Additionally, we conducted tests on a mouse model of AR, administering taurine to see how it affected sneezing, inflammation, and the overall condition of the nasal mucosa.
Our findings revealed that taurine promotes the production of IL-35, a cytokine that, in turn, stimulates the creation of Tregs through the STAT1 signaling pathway. By increasing Treg populations, taurine helps to normalize the immune response, alleviating symptoms of allergic rhinitis and even improving histological signs associated with the condition. Through this research, we clearly demonstrated taurine's promising potential in managing allergies effectively and safely.
In our investigation, we looked at blood samples from individuals, both healthy donors and AR patients, to determine the effects of taurine on T regulatory cells, or Tregs, which are crucial for regulating immune responses. We also examined how taurine might influence specific cytokines involved in allergic reactions and help restore normal nasal function. Additionally, we conducted tests on a mouse model of AR, administering taurine to see how it affected sneezing, inflammation, and the overall condition of the nasal mucosa.
Our findings revealed that taurine promotes the production of IL-35, a cytokine that, in turn, stimulates the creation of Tregs through the STAT1 signaling pathway. By increasing Treg populations, taurine helps to normalize the immune response, alleviating symptoms of allergic rhinitis and even improving histological signs associated with the condition. Through this research, we clearly demonstrated taurine's promising potential in managing allergies effectively and safely.
Read More
9
We're diving into the potential of taurine as a treatment for allergic rhinitis (AR). This study set out to examine how taurine can impact AR and the mechanisms behind its effects. We looked at patients with AR and measured the levels of an important antioxidant enzyme called SOD3, finding that those with AR had lower levels compared to healthy individuals.
To understand taurine's effects further, we tested it on cells from a human mast cell line and in an animal model that mimics AR symptoms. Our findings showed that taurine treatment led to an increase in SOD3 levels in a dose-dependent manner, suggesting it boosts the body’s ability to combat inflammation. Importantly, this increase in SOD3 was linked to the activity of a receptor called PPAR-γ, which then helped reduce the release of inflammatory substances associated with allergic reactions.
In the animal model, taurine eased allergic symptoms and reduced the number of eosinophils and mast cells in the nasal cavity, key players in allergic responses. Overall, taurine showed promise in enhancing SOD3 production, which contributed to its beneficial effects against inflammation in allergies. This suggests that taurine could be a valuable addition to the current treatment options for allergic disorders.
To understand taurine's effects further, we tested it on cells from a human mast cell line and in an animal model that mimics AR symptoms. Our findings showed that taurine treatment led to an increase in SOD3 levels in a dose-dependent manner, suggesting it boosts the body’s ability to combat inflammation. Importantly, this increase in SOD3 was linked to the activity of a receptor called PPAR-γ, which then helped reduce the release of inflammatory substances associated with allergic reactions.
In the animal model, taurine eased allergic symptoms and reduced the number of eosinophils and mast cells in the nasal cavity, key players in allergic responses. Overall, taurine showed promise in enhancing SOD3 production, which contributed to its beneficial effects against inflammation in allergies. This suggests that taurine could be a valuable addition to the current treatment options for allergic disorders.
Read More
9
Taurine mitigates food allergy damage
We explored the effects of taurine on intestinal damage caused by cow's milk protein, specifically beta-lactoglobulin (β-Lg), in a study using Balb/c mice. By administering taurine either orally or intraperitoneally for two weeks, we aimed to understand how it might prevent the allergic reactions that often lead to chronic inflammation in infants.
After sensitizing the mice to β-Lg, we measured important electrical properties of their intestinal epithelium in a controlled setting. Surprisingly, we found that pre-treatment with taurine did not alter the active ion transport or passive ion permeability in the intestines, suggesting a reduced secretory response and improved intestinal barrier function.
Additionally, histological evaluations indicated that taurine treatment significantly diminished intestinal damage and retraction following sensitization. While there were no notable changes in inflammatory markers TNF-α and IL-6, we did observe that taurine effectively lowered serum levels of both IgG and IgE antibodies specific to β-Lg, underscoring its potential to mitigate allergic responses.
Overall, our findings suggest that taurine is a promising candidate for preventing intestinal damage related to cow's milk allergies, although further research is necessary to fully understand its mechanisms and confirm its effectiveness in broader contexts.
After sensitizing the mice to β-Lg, we measured important electrical properties of their intestinal epithelium in a controlled setting. Surprisingly, we found that pre-treatment with taurine did not alter the active ion transport or passive ion permeability in the intestines, suggesting a reduced secretory response and improved intestinal barrier function.
Additionally, histological evaluations indicated that taurine treatment significantly diminished intestinal damage and retraction following sensitization. While there were no notable changes in inflammatory markers TNF-α and IL-6, we did observe that taurine effectively lowered serum levels of both IgG and IgE antibodies specific to β-Lg, underscoring its potential to mitigate allergic responses.
Overall, our findings suggest that taurine is a promising candidate for preventing intestinal damage related to cow's milk allergies, although further research is necessary to fully understand its mechanisms and confirm its effectiveness in broader contexts.
Read More
Most Useful Reviews
9
Effective for allergies
Excellent quality product. The ingredients are well chosen. There were no allergies or negative reactions. The package size is adequate for long-term use. The capsules are of medium size, and the taste is neutral. The badge arrived quickly and undamaged. The composition contains useful natural ingredients and folic acid. My bowel function and metabolism improved, with noticeable results after a week. I found my nervous system functioning better and I felt less anxious. I have complete confidence in this vitamin's effectiveness. Ensure to check your dosage for your age.
Read More
9
Good for energy
Fabulous! It acts like an energy drink for me. Excellent quality product with well-selected ingredients. No allergies or negative reactions were experienced. The packaging is substantial, lasting long. Capsules are of medium size and neutral in taste. The dietary supplement arrived promptly and without damage. It contains only beneficial natural elements and folic acid. Improvements in bowel function and metabolism were noticeable within a week. My nervous system functioned better, and my nerves were calmer. I am fully confident in the vitamin's effectiveness. Thanks for the likes!
Read More
9
Trustworthy supplement
Great supplement! This product is of excellent quality with perfectly selected ingredients. It caused no allergies or adverse reactions. The large packaging ensures long-lasting use. Medium-sized capsules feature a neutral taste and were delivered quickly and undamaged. The composition consists of only useful natural components and folic acid. I observed improvements in bowel function and metabolism within a week. My nervous system functions better, and I feel less anxious. There is no doubt about the product's effectiveness for me.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.5
- All Researches
9
We explored how taurine, an amino acid that might seem simple, plays a significant role in helping people with allergic rhinitis (AR). Allergic rhinitis, a common condition, can cause a lot of discomfort, and while various treatments are available, many come with unwanted side effects. Our focus was to see if taurine could be an effective and safer alternative for managing AR symptoms.
In our investigation, we looked at blood samples from individuals, both healthy donors and AR patients, to determine the effects of taurine on T regulatory cells, or Tregs, which are crucial for regulating immune responses. We also examined how taurine might influence specific cytokines involved in allergic reactions and help restore normal nasal function. Additionally, we conducted tests on a mouse model of AR, administering taurine to see how it affected sneezing, inflammation, and the overall condition of the nasal mucosa.
Our findings revealed that taurine promotes the production of IL-35, a cytokine that, in turn, stimulates the creation of Tregs through the STAT1 signaling pathway. By increasing Treg populations, taurine helps to normalize the immune response, alleviating symptoms of allergic rhinitis and even improving histological signs associated with the condition. Through this research, we clearly demonstrated taurine's promising potential in managing allergies effectively and safely.
In our investigation, we looked at blood samples from individuals, both healthy donors and AR patients, to determine the effects of taurine on T regulatory cells, or Tregs, which are crucial for regulating immune responses. We also examined how taurine might influence specific cytokines involved in allergic reactions and help restore normal nasal function. Additionally, we conducted tests on a mouse model of AR, administering taurine to see how it affected sneezing, inflammation, and the overall condition of the nasal mucosa.
Our findings revealed that taurine promotes the production of IL-35, a cytokine that, in turn, stimulates the creation of Tregs through the STAT1 signaling pathway. By increasing Treg populations, taurine helps to normalize the immune response, alleviating symptoms of allergic rhinitis and even improving histological signs associated with the condition. Through this research, we clearly demonstrated taurine's promising potential in managing allergies effectively and safely.
Read More
9
We're diving into the potential of taurine as a treatment for allergic rhinitis (AR). This study set out to examine how taurine can impact AR and the mechanisms behind its effects. We looked at patients with AR and measured the levels of an important antioxidant enzyme called SOD3, finding that those with AR had lower levels compared to healthy individuals.
To understand taurine's effects further, we tested it on cells from a human mast cell line and in an animal model that mimics AR symptoms. Our findings showed that taurine treatment led to an increase in SOD3 levels in a dose-dependent manner, suggesting it boosts the body’s ability to combat inflammation. Importantly, this increase in SOD3 was linked to the activity of a receptor called PPAR-γ, which then helped reduce the release of inflammatory substances associated with allergic reactions.
In the animal model, taurine eased allergic symptoms and reduced the number of eosinophils and mast cells in the nasal cavity, key players in allergic responses. Overall, taurine showed promise in enhancing SOD3 production, which contributed to its beneficial effects against inflammation in allergies. This suggests that taurine could be a valuable addition to the current treatment options for allergic disorders.
To understand taurine's effects further, we tested it on cells from a human mast cell line and in an animal model that mimics AR symptoms. Our findings showed that taurine treatment led to an increase in SOD3 levels in a dose-dependent manner, suggesting it boosts the body’s ability to combat inflammation. Importantly, this increase in SOD3 was linked to the activity of a receptor called PPAR-γ, which then helped reduce the release of inflammatory substances associated with allergic reactions.
In the animal model, taurine eased allergic symptoms and reduced the number of eosinophils and mast cells in the nasal cavity, key players in allergic responses. Overall, taurine showed promise in enhancing SOD3 production, which contributed to its beneficial effects against inflammation in allergies. This suggests that taurine could be a valuable addition to the current treatment options for allergic disorders.
Read More
9
Taurine mitigates food allergy damage
We explored the effects of taurine on intestinal damage caused by cow's milk protein, specifically beta-lactoglobulin (β-Lg), in a study using Balb/c mice. By administering taurine either orally or intraperitoneally for two weeks, we aimed to understand how it might prevent the allergic reactions that often lead to chronic inflammation in infants.
After sensitizing the mice to β-Lg, we measured important electrical properties of their intestinal epithelium in a controlled setting. Surprisingly, we found that pre-treatment with taurine did not alter the active ion transport or passive ion permeability in the intestines, suggesting a reduced secretory response and improved intestinal barrier function.
Additionally, histological evaluations indicated that taurine treatment significantly diminished intestinal damage and retraction following sensitization. While there were no notable changes in inflammatory markers TNF-α and IL-6, we did observe that taurine effectively lowered serum levels of both IgG and IgE antibodies specific to β-Lg, underscoring its potential to mitigate allergic responses.
Overall, our findings suggest that taurine is a promising candidate for preventing intestinal damage related to cow's milk allergies, although further research is necessary to fully understand its mechanisms and confirm its effectiveness in broader contexts.
After sensitizing the mice to β-Lg, we measured important electrical properties of their intestinal epithelium in a controlled setting. Surprisingly, we found that pre-treatment with taurine did not alter the active ion transport or passive ion permeability in the intestines, suggesting a reduced secretory response and improved intestinal barrier function.
Additionally, histological evaluations indicated that taurine treatment significantly diminished intestinal damage and retraction following sensitization. While there were no notable changes in inflammatory markers TNF-α and IL-6, we did observe that taurine effectively lowered serum levels of both IgG and IgE antibodies specific to β-Lg, underscoring its potential to mitigate allergic responses.
Overall, our findings suggest that taurine is a promising candidate for preventing intestinal damage related to cow's milk allergies, although further research is necessary to fully understand its mechanisms and confirm its effectiveness in broader contexts.
Read More
9
We aimed to understand how taurine, a compound known for its potential benefits in chronic inflammation, affects allergic responses. By looking at human mast cell line HMC-1 cells exposed to specific triggers, we evaluated taurine's ability to modulate various pro-inflammatory markers.
Our findings revealed that taurine significantly reduced levels of thymic stromal lymphopoietin (TSLP) and other inflammatory cytokines. It also blunted key signaling pathways involved in allergic reactions, such as the phosphorylation of JNK and p38, while inhibiting the activities of NF-κB and caspase-1.
In animal models of allergic rhinitis induced by ovalbumin, we saw that taurine could effectively diminish symptoms such as nose rubbing and lower levels of histamine and immunoglobulin E. Overall, these results suggest that taurine might serve as a promising new treatment option for allergic inflammatory disorders.
Our findings revealed that taurine significantly reduced levels of thymic stromal lymphopoietin (TSLP) and other inflammatory cytokines. It also blunted key signaling pathways involved in allergic reactions, such as the phosphorylation of JNK and p38, while inhibiting the activities of NF-κB and caspase-1.
In animal models of allergic rhinitis induced by ovalbumin, we saw that taurine could effectively diminish symptoms such as nose rubbing and lower levels of histamine and immunoglobulin E. Overall, these results suggest that taurine might serve as a promising new treatment option for allergic inflammatory disorders.
Read More
8
We set out to understand how the chemical chaperone TUDCA (tauroursodeoxycholic acid) impacts allergic responses, particularly the production of allergen-specific IgE. In our study, we used a low-dose model of allergy, administering a small amount of ovalbumin to BALB/c mice over six weeks to simulate an allergic reaction.
Our findings showed that TUDCA significantly reduced the production of allergen-specific IgE, which is a key player in allergic reactions, by about 2.5 times. Interestingly, we didn’t observe a similar effect with another chemical chaperone called 4-PBA, which did not influence IgE levels.
The mechanism behind TUDCA's effectiveness seems to involve a reduction in the expression of cytokines related to type 2 immune responses, including IL-4 and IL-9, likely due to decreased levels of IL-33. TUDCA also affected the expression of two important cytokines, APRIL and BAFF, further supporting its role in allergy management. Overall, these results suggest that TUDCA might be a beneficial treatment for allergies by selectively inhibiting the production of IgE.
Our findings showed that TUDCA significantly reduced the production of allergen-specific IgE, which is a key player in allergic reactions, by about 2.5 times. Interestingly, we didn’t observe a similar effect with another chemical chaperone called 4-PBA, which did not influence IgE levels.
The mechanism behind TUDCA's effectiveness seems to involve a reduction in the expression of cytokines related to type 2 immune responses, including IL-4 and IL-9, likely due to decreased levels of IL-33. TUDCA also affected the expression of two important cytokines, APRIL and BAFF, further supporting its role in allergy management. Overall, these results suggest that TUDCA might be a beneficial treatment for allergies by selectively inhibiting the production of IgE.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for allergies
Excellent quality product. The ingredients are well chosen. There were no allergies or negative reactions. The package size is adequate for long-term use. The capsules are of medium size, and the taste is neutral. The badge arrived quickly and undamaged. The composition contains useful natural ingredients and folic acid. My bowel function and metabolism improved, with noticeable results after a week. I found my nervous system functioning better and I felt less anxious. I have complete confidence in this vitamin's effectiveness. Ensure to check your dosage for your age.
Read More
9
Good for energy
Fabulous! It acts like an energy drink for me. Excellent quality product with well-selected ingredients. No allergies or negative reactions were experienced. The packaging is substantial, lasting long. Capsules are of medium size and neutral in taste. The dietary supplement arrived promptly and without damage. It contains only beneficial natural elements and folic acid. Improvements in bowel function and metabolism were noticeable within a week. My nervous system functioned better, and my nerves were calmer. I am fully confident in the vitamin's effectiveness. Thanks for the likes!
Read More
9
Trustworthy supplement
Great supplement! This product is of excellent quality with perfectly selected ingredients. It caused no allergies or adverse reactions. The large packaging ensures long-lasting use. Medium-sized capsules feature a neutral taste and were delivered quickly and undamaged. The composition consists of only useful natural components and folic acid. I observed improvements in bowel function and metabolism within a week. My nervous system functions better, and I feel less anxious. There is no doubt about the product's effectiveness for me.
Read More
9
No negative reactions
Super Excellent quality product with perfectly selected ingredients, and I experienced no allergies or adverse reactions. The large packaging will last a long time and the capsules are medium-sized. The taste is neutral, and the dietary supplement arrived promptly and undamaged. It includes useful, natural components and folic acid. Improvements in bowel function and metabolism were noticeable after a week. My nervous system functioned better, and I felt less nervous. I liked everything about this supplement and have no doubt about its effectiveness. Be sure to check your dosage for age.
Read More
Frequently Asked Questions
9
Trustworthy supplement
Great supplement! This product is of excellent quality with perfectly selected ingredients. It caused no allergies or adverse reactions. The large packaging ensures long-lasting use. Medium-sized capsules feature a neutral taste and were delivered quickly and undamaged. The composition consists of only useful natural components and folic acid. I observed improvements in bowel function and metabolism within a week. My nervous system functions better, and I feel less anxious. There is no doubt about the product's effectiveness for me.
9
Effective for allergies
Excellent quality product. The ingredients are well chosen. There were no allergies or negative reactions. The package size is adequate for long-term use. The capsules are of medium size, and the taste is neutral. The badge arrived quickly and undamaged. The composition contains useful natural ingredients and folic acid. My bowel function and metabolism improved, with noticeable results after a week. I found my nervous system functioning better and I felt less anxious. I have complete confidence in this vitamin's effectiveness. Ensure to check your dosage for your age.
9
Good for energy
Fabulous! It acts like an energy drink for me. Excellent quality product with well-selected ingredients. No allergies or negative reactions were experienced. The packaging is substantial, lasting long. Capsules are of medium size and neutral in taste. The dietary supplement arrived promptly and without damage. It contains only beneficial natural elements and folic acid. Improvements in bowel function and metabolism were noticeable within a week. My nervous system functioned better, and my nerves were calmer. I am fully confident in the vitamin's effectiveness. Thanks for the likes!
9
No negative reactions
Super Excellent quality product with perfectly selected ingredients, and I experienced no allergies or adverse reactions. The large packaging will last a long time and the capsules are medium-sized. The taste is neutral, and the dietary supplement arrived promptly and undamaged. It includes useful, natural components and folic acid. Improvements in bowel function and metabolism were noticeable after a week. My nervous system functioned better, and I felt less nervous. I liked everything about this supplement and have no doubt about its effectiveness. Be sure to check your dosage for age.
8
We set out to understand how the chemical chaperone TUDCA (tauroursodeoxycholic acid) impacts allergic responses, particularly the production of allergen-specific IgE. In our study, we used a low-dose model of allergy, administering a small amount of ovalbumin to BALB/c mice over six weeks to simulate an allergic reaction.
Our findings showed that TUDCA significantly reduced the production of allergen-specific IgE, which is a key player in allergic reactions, by about 2.5 times. Interestingly, we didn’t observe a similar effect with another chemical chaperone called 4-PBA, which did not influence IgE levels.
The mechanism behind TUDCA's effectiveness seems to involve a reduction in the expression of cytokines related to type 2 immune responses, including IL-4 and IL-9, likely due to decreased levels of IL-33. TUDCA also affected the expression of two important cytokines, APRIL and BAFF, further supporting its role in allergy management. Overall, these results suggest that TUDCA might be a beneficial treatment for allergies by selectively inhibiting the production of IgE.
Our findings showed that TUDCA significantly reduced the production of allergen-specific IgE, which is a key player in allergic reactions, by about 2.5 times. Interestingly, we didn’t observe a similar effect with another chemical chaperone called 4-PBA, which did not influence IgE levels.
The mechanism behind TUDCA's effectiveness seems to involve a reduction in the expression of cytokines related to type 2 immune responses, including IL-4 and IL-9, likely due to decreased levels of IL-33. TUDCA also affected the expression of two important cytokines, APRIL and BAFF, further supporting its role in allergy management. Overall, these results suggest that TUDCA might be a beneficial treatment for allergies by selectively inhibiting the production of IgE.
9
We explored how taurine, an amino acid that might seem simple, plays a significant role in helping people with allergic rhinitis (AR). Allergic rhinitis, a common condition, can cause a lot of discomfort, and while various treatments are available, many come with unwanted side effects. Our focus was to see if taurine could be an effective and safer alternative for managing AR symptoms.
In our investigation, we looked at blood samples from individuals, both healthy donors and AR patients, to determine the effects of taurine on T regulatory cells, or Tregs, which are crucial for regulating immune responses. We also examined how taurine might influence specific cytokines involved in allergic reactions and help restore normal nasal function. Additionally, we conducted tests on a mouse model of AR, administering taurine to see how it affected sneezing, inflammation, and the overall condition of the nasal mucosa.
Our findings revealed that taurine promotes the production of IL-35, a cytokine that, in turn, stimulates the creation of Tregs through the STAT1 signaling pathway. By increasing Treg populations, taurine helps to normalize the immune response, alleviating symptoms of allergic rhinitis and even improving histological signs associated with the condition. Through this research, we clearly demonstrated taurine's promising potential in managing allergies effectively and safely.
In our investigation, we looked at blood samples from individuals, both healthy donors and AR patients, to determine the effects of taurine on T regulatory cells, or Tregs, which are crucial for regulating immune responses. We also examined how taurine might influence specific cytokines involved in allergic reactions and help restore normal nasal function. Additionally, we conducted tests on a mouse model of AR, administering taurine to see how it affected sneezing, inflammation, and the overall condition of the nasal mucosa.
Our findings revealed that taurine promotes the production of IL-35, a cytokine that, in turn, stimulates the creation of Tregs through the STAT1 signaling pathway. By increasing Treg populations, taurine helps to normalize the immune response, alleviating symptoms of allergic rhinitis and even improving histological signs associated with the condition. Through this research, we clearly demonstrated taurine's promising potential in managing allergies effectively and safely.
9
We aimed to understand how taurine, a compound known for its potential benefits in chronic inflammation, affects allergic responses. By looking at human mast cell line HMC-1 cells exposed to specific triggers, we evaluated taurine's ability to modulate various pro-inflammatory markers.
Our findings revealed that taurine significantly reduced levels of thymic stromal lymphopoietin (TSLP) and other inflammatory cytokines. It also blunted key signaling pathways involved in allergic reactions, such as the phosphorylation of JNK and p38, while inhibiting the activities of NF-κB and caspase-1.
In animal models of allergic rhinitis induced by ovalbumin, we saw that taurine could effectively diminish symptoms such as nose rubbing and lower levels of histamine and immunoglobulin E. Overall, these results suggest that taurine might serve as a promising new treatment option for allergic inflammatory disorders.
Our findings revealed that taurine significantly reduced levels of thymic stromal lymphopoietin (TSLP) and other inflammatory cytokines. It also blunted key signaling pathways involved in allergic reactions, such as the phosphorylation of JNK and p38, while inhibiting the activities of NF-κB and caspase-1.
In animal models of allergic rhinitis induced by ovalbumin, we saw that taurine could effectively diminish symptoms such as nose rubbing and lower levels of histamine and immunoglobulin E. Overall, these results suggest that taurine might serve as a promising new treatment option for allergic inflammatory disorders.
7
We aimed to uncover whether certain metabolites could predict the effectiveness of subcutaneous immunotherapy in treating allergic rhinitis caused by Artemisia sieversiana pollen. In our study, 43 patients with this specific allergy underwent a year-long treatment. By comparing their serum samples before treatment, we categorized them into two groups: those who found the treatment effective and those who did not.
Through advanced analysis techniques, we identified 129 different metabolites that showed significant variations between the two groups. Among the key players, taurine stood out, alongside hypotaurine and l-alanine, indicating their potential role as biomarkers predicting the success of immunotherapy.
Our findings suggest that these metabolites could offer insights into how well individuals might respond to treatment, ultimately leading to more personalized allergy management. However, it’s important to note that while taurine is a promising candidate, our research does not confirm it as a standalone treatment for allergies.
Overall, this discovery could help streamline treatment options and improve outcomes for patients dealing with seasonal allergies.
Through advanced analysis techniques, we identified 129 different metabolites that showed significant variations between the two groups. Among the key players, taurine stood out, alongside hypotaurine and l-alanine, indicating their potential role as biomarkers predicting the success of immunotherapy.
Our findings suggest that these metabolites could offer insights into how well individuals might respond to treatment, ultimately leading to more personalized allergy management. However, it’s important to note that while taurine is a promising candidate, our research does not confirm it as a standalone treatment for allergies.
Overall, this discovery could help streamline treatment options and improve outcomes for patients dealing with seasonal allergies.
References
- Chudakov DB, Shustova OA, Kotsareva OD, Generalov AA, Streltsova MS, et al. Chemical chaperone TUDCA selectively inhibits production of allergen-specific IgE in a low-dose model of allergy. Biomed Khim. 2024;70:5. doi:10.18097/PBMC20247001005
- Yu RL, Pan C, Ma TT, Wang XY, Shi HY, et al. Prediction of clinical efficacy of subcutaneous immunotherapy for Artemisia sieversiana pollen allergic rhinitis by serum metabolomics. J Formos Med Assoc. 2022;121:2465. doi:10.1016/j.jfma.2022.05.006
- Zhou J, Lu Y, Wu W, Feng Y. Taurine promotes the production of CD4CD25FOXP3 Treg cells through regulating IL-35/STAT1 pathway in a mouse allergic rhinitis model. Allergy Asthma Clin Immunol. 2021;17:59. doi:10.1186/s13223-021-00562-1
- Zhou J, Lu Y, Li F, Wu W, Xie D, et al. In vitro and in vivo Antiallergic Effects of Taurine on Allergic Rhinitis. Int Arch Allergy Immunol. 2020;181:404. doi:10.1159/000505209
- Aïnad-Tabet S, Grar H, Haddi A, Negaoui H, Guermat A, et al. Taurine administration prevents the intestine from the damage induced by beta-lactoglobulin sensitization in a murine model of food allergy. Allergol Immunopathol (Madr). 2019;47:214. doi:10.1016/j.aller.2018.07.010
- Nam SY, Kim HM, Jeong HJ. The potential protective role of taurine against experimental allergic inflammation. Life Sci. 2017;184:18. doi:10.1016/j.lfs.2017.07.007
