Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.2
USERS' SCORE
Good
Based on 14 Reviews
8
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Turmeric Root Extract (Curcuma longa) (Standardized to min. 95% Curcuminoids)
600 mg
*
Bromelain (2400 GDU/g)† (from Pineapple)
300 mg
*
Top Medical Research Studies
8
We explored a new way to deliver bromelain, a natural enzyme, using nanostructured lipid carriers (Br-NCs).
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Read More
8
We evaluated the effects of a new glucosamine combination, which includes bromelain, on cartilage damage in rats induced by formalin. The study involved different groups of rats, including a control group, and assessed various biochemical and gene expression markers after 30 days of treatment.
Our findings showed that the new combination significantly reduced markers of inflammation and oxidative damage while improving antioxidants compared to the control group. Notably, this new formula helped protect cartilage, indicating its potential clinical relevance for osteoarthritis treatment. However, the standard glucosamine combination did not demonstrate similar benefits.
Our findings showed that the new combination significantly reduced markers of inflammation and oxidative damage while improving antioxidants compared to the control group. Notably, this new formula helped protect cartilage, indicating its potential clinical relevance for osteoarthritis treatment. However, the standard glucosamine combination did not demonstrate similar benefits.
Read More
4
We aimed to understand how bromelain, an enzyme from pineapples, affects knee osteoarthritis (OA) over a 16-week period. Our randomized, single-blind pilot study involved 40 participants who received either bromelain or diclofenac.
While both groups showed improvements in pain and function after four weeks, no significant differences emerged between the treatments. By week 16, bromelain users showed some enhancements in WOMAC scores and reductions in oxidative stress markers. However, bromelain didn't significantly outperform diclofenac in relieving OA symptoms.
While both groups showed improvements in pain and function after four weeks, no significant differences emerged between the treatments. By week 16, bromelain users showed some enhancements in WOMAC scores and reductions in oxidative stress markers. However, bromelain didn't significantly outperform diclofenac in relieving OA symptoms.
Read More
Most Useful Reviews
7.5
Inflammation management
86 people found this helpful
Great for my fibro and arthritis. Awesome for inflammation! I take this supplement three times daily to combat inflammation from fibromyalgia and arthritis. I notice a huge difference when I miss a dose. Highly recommend for any inflammatory condition, as well as magnesium.
Read More
9
Effective pain relief
12 people found this helpful
Great for arthritis pain. This product works on my arthritis better than more expensive brands. I live in Michigan and have pain in my joints, especially one knee. If I take this regularly, the pain disappears. I will always have this in my cabinet.
Read More
9
Preferred product found
10 people found this helpful
Mediocre product. Now Foods does not state the quantity of turmeric extract in their product. I used a bottle and then ordered the Jarrow product, which contains 500 mg of turmeric extract - stated on the Jarrow label. The Jarrow product is superior, giving me great relief from RA arthritis joint pain.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.2
- All Researches
8
We explored a new way to deliver bromelain, a natural enzyme, using nanostructured lipid carriers (Br-NCs).
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Read More
8
This pilot study focused on whether a food supplement containing bromelain and Boswellia could enhance the quality of life for osteoarthritis (OA) patients. Over 49 participants took the supplement for 1 to 6 months and reported on their daily activities.
We found that, after treatment, 7 out of 10 questions regarding patient quality of life showed significant improvements, especially in the joints most affected. Notably, no adverse effects were reported.
These findings suggest that this combination may serve as a helpful, non-drug option for OA patients, paving the way for further research.
We found that, after treatment, 7 out of 10 questions regarding patient quality of life showed significant improvements, especially in the joints most affected. Notably, no adverse effects were reported.
These findings suggest that this combination may serve as a helpful, non-drug option for OA patients, paving the way for further research.
Read More
8
We evaluated the effects of a new glucosamine combination, which includes bromelain, on cartilage damage in rats induced by formalin. The study involved different groups of rats, including a control group, and assessed various biochemical and gene expression markers after 30 days of treatment.
Our findings showed that the new combination significantly reduced markers of inflammation and oxidative damage while improving antioxidants compared to the control group. Notably, this new formula helped protect cartilage, indicating its potential clinical relevance for osteoarthritis treatment. However, the standard glucosamine combination did not demonstrate similar benefits.
Our findings showed that the new combination significantly reduced markers of inflammation and oxidative damage while improving antioxidants compared to the control group. Notably, this new formula helped protect cartilage, indicating its potential clinical relevance for osteoarthritis treatment. However, the standard glucosamine combination did not demonstrate similar benefits.
Read More
8
We evaluated how a blend of three natural ingredients—Devil's claw, turmeric, and bromelain—could help alleviate osteoarthritis pain. Conducted in eight rheumatology centers, the study looked at both acute and chronic pain experienced by 42 participants, mostly women around 67 years old.
After taking AINAT capsules, patients reported a significant reduction in joint pain within three days for acute cases and 60 days for chronic cases. With an excellent safety profile, this natural remedy offers a promising alternative to conventional painkillers for those suffering from joint discomfort.
After taking AINAT capsules, patients reported a significant reduction in joint pain within three days for acute cases and 60 days for chronic cases. With an excellent safety profile, this natural remedy offers a promising alternative to conventional painkillers for those suffering from joint discomfort.
Read More
8
We explored how bromelain affects mild acute knee pain in healthy individuals. This study involved volunteers taking either 200 mg or 400 mg of bromelain per day for a month.
The results were promising: both dosage groups reported significant reductions in pain and overall improvement in well-being. The high-dose group experienced even greater benefits, suggesting that more bromelain leads to better outcomes.
However, further double-blind, placebo-controlled studies are necessary to confirm these findings and fully understand bromelain's role in joint health.
The results were promising: both dosage groups reported significant reductions in pain and overall improvement in well-being. The high-dose group experienced even greater benefits, suggesting that more bromelain leads to better outcomes.
However, further double-blind, placebo-controlled studies are necessary to confirm these findings and fully understand bromelain's role in joint health.
Read More
User Reviews
USERS' SCORE
Good
Based on 14 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Inflammation management
86 people found this helpful
Great for my fibro and arthritis. Awesome for inflammation! I take this supplement three times daily to combat inflammation from fibromyalgia and arthritis. I notice a huge difference when I miss a dose. Highly recommend for any inflammatory condition, as well as magnesium.
Read More
9
Effective pain relief
12 people found this helpful
Great for arthritis pain. This product works on my arthritis better than more expensive brands. I live in Michigan and have pain in my joints, especially one knee. If I take this regularly, the pain disappears. I will always have this in my cabinet.
Read More
9
Preferred product found
10 people found this helpful
Mediocre product. Now Foods does not state the quantity of turmeric extract in their product. I used a bottle and then ordered the Jarrow product, which contains 500 mg of turmeric extract - stated on the Jarrow label. The Jarrow product is superior, giving me great relief from RA arthritis joint pain.
Read More
9
Eliminated prescription meds
3 people found this helpful
Controls my arthritis pain! I have eliminated my prescription medicine for arthritis in my knees by using this supplement. I haven’t needed the prescription for over a year, thanks to Mother Nature!
Read More
9
Significant pain decrease
3 people found this helpful
Definitely worth every penny! This has been an amazing supplement for my daughter. She has arthritis and severe joint pain in her knees. Within less than 2 weeks of taking these pills, her pain has significantly decreased, and the swelling has reduced. She takes four pills a day. I’m definitely a fan of Now Foods turmeric and keep this on hand.
Read More
Frequently Asked Questions
9
Pain relief achieved
2 people found this helpful
It’s effective! Since I began taking this dietary supplement not long ago, I have already noticed a difference. My rheumatoid arthritis pain has diminished, and my hands are functioning better. The discomfort from rheumatism has subsided. However, I didn’t like that the capsules do have a slight wakefulness effect. The powder inside is yellow, reminiscent of turmeric.
6
Boosts immune system
1 people found this helpful
Turmeric contains essential oils rich in phosphorus, iron, iodine, calcium, choline, and B vitamins. Its benefits derive from the beneficial substances present, helping with inflammation and arthritis while supporting metabolic processes. It also strengthens immunity and overall wellness. I felt more energetic after two weeks of taking it, and my recovery from illness was quick, which I attribute to it.
7.5
Nerve inflammation relief
1 people found this helpful
Wonderful and beneficial for inflammation of the nerves, it eliminates pulsed electricity and arthritis pain effectively.
7
We observed that human synovial cells from osteoarthritis (OA) patients respond to lipopolysaccharide (LPS) by mimicking changes seen in inflamed joint tissues. Our study tested a unique blend of curcumin, bromelain, and harpagophytum for their potential to reduce inflammation.
The results showed that this combination of natural compounds has anti-inflammatory and anti-catabolic effects. This suggests they might help alleviate pain and slow the progression of OA, offering a glimpse of hope for those battling this common form of arthritis.
The results showed that this combination of natural compounds has anti-inflammatory and anti-catabolic effects. This suggests they might help alleviate pain and slow the progression of OA, offering a glimpse of hope for those battling this common form of arthritis.
8
We explored a new way to deliver bromelain, a natural enzyme, using nanostructured lipid carriers (Br-NCs).
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis.
8
This pilot study focused on whether a food supplement containing bromelain and Boswellia could enhance the quality of life for osteoarthritis (OA) patients. Over 49 participants took the supplement for 1 to 6 months and reported on their daily activities.
We found that, after treatment, 7 out of 10 questions regarding patient quality of life showed significant improvements, especially in the joints most affected. Notably, no adverse effects were reported.
These findings suggest that this combination may serve as a helpful, non-drug option for OA patients, paving the way for further research.
We found that, after treatment, 7 out of 10 questions regarding patient quality of life showed significant improvements, especially in the joints most affected. Notably, no adverse effects were reported.
These findings suggest that this combination may serve as a helpful, non-drug option for OA patients, paving the way for further research.
4
We aimed to understand how bromelain, an enzyme from pineapples, affects knee osteoarthritis (OA) over a 16-week period. Our randomized, single-blind pilot study involved 40 participants who received either bromelain or diclofenac.
While both groups showed improvements in pain and function after four weeks, no significant differences emerged between the treatments. By week 16, bromelain users showed some enhancements in WOMAC scores and reductions in oxidative stress markers. However, bromelain didn't significantly outperform diclofenac in relieving OA symptoms.
While both groups showed improvements in pain and function after four weeks, no significant differences emerged between the treatments. By week 16, bromelain users showed some enhancements in WOMAC scores and reductions in oxidative stress markers. However, bromelain didn't significantly outperform diclofenac in relieving OA symptoms.
7
We explored how an oral enzyme combination, including bromelain, stacks up against diclofenac for treating knee osteoarthritis. In a well-designed study involving 103 patients over six weeks, both treatments showed improvements in pain and function.
The enzyme combination was found to be non-inferior to diclofenac, showing similar benefits in pain relief and functionality. Interestingly, the enzyme treatment even received better ratings from physicians for efficacy in some cases.
While both options were well-tolerated, further placebo-controlled studies are needed for confirmation.
The enzyme combination was found to be non-inferior to diclofenac, showing similar benefits in pain relief and functionality. Interestingly, the enzyme treatment even received better ratings from physicians for efficacy in some cases.
While both options were well-tolerated, further placebo-controlled studies are needed for confirmation.
References
- Brochard S, Pontin J, Bernay B, Boumediene K, Conrozier T, et al. The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells. BMC Complement Med Ther. 2021;21:261. doi:10.1186/s12906-021-03435-7
- Sharma M, Chaudhary D. Exploration of bromelain laden nanostructured lipid carriers: An oral platform for bromelain delivery in rheumatoid arthritis management. Int J Pharm. 2021;594:120176. doi:10.1016/j.ijpharm.2020.120176
- Italiano G, Raimondo M, Giannetti G, Gargiulo A. Benefits of a Food Supplement Containing and Bromelain for Improving the Quality of Life in Patients with Osteoarthritis: A Pilot Study. J Altern Complement Med. 2020;26:123. doi:10.1089/acm.2019.0258
- Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016;35:2531. doi:10.1007/s10067-016-3363-1
- Ucuncu Y, Celik N, Ozturk C, Turkoglu M, Cetin N, et al. Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation. Life Sci. 2015;130:31. doi:10.1016/j.lfs.2015.03.012
- Conrozier T, Mathieu P, Bonjean M, Marc JF, Renevier JL, et al. A complex of three natural anti-inflammatory agents provides relief of osteoarthritis pain. Altern Ther Health Med. 2014;20 Suppl 1:32.
- Akhtar NM, Naseer R, Farooqi AZ, Aziz W, Nazir M. Oral enzyme combination versus diclofenac in the treatment of osteoarthritis of the knee--a double-blind prospective randomized study. Clin Rheumatol. 2004;23:410.
- Walker AF, Bundy R, Hicks SM, Middleton RW. Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults. Phytomedicine. 2002;9:681.
- Desser L, Holomanova D, Zavadova E, Pavelka K, Mohr T, et al. Oral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human blood. Cancer Chemother Pharmacol. 2001;47 Suppl:S10.
