Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
USERS' SCORE
Good
Based on 13 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (from Thiamin HCl) (Vitamin B-1)
100 mg
8333%
Riboflavin (Vitamin B-2)
100 mg
7692%
Niacin (Vitamin B-3) (as Niacinamide)
100 mg
625%
Vitamin B-6 (from Pyridoxine HCl)
100 mg
5882%
Folate
680 mcg DFE(400 mcg folic acid)
170%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4167%
Biotin
100 mcg
333%
Pantothenic Acid (from Calcium Pantothenate)
100 mg
2000%
Choline (from Choline Bitartrate)
35 mg
6%
Inositol
100 mg
PABA (Para-Aminobenzoic Acid)
10 mg

Top Medical Research Studies

9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
8
Methylcobalamin shows promising effectiveness
This study evaluated the effects of intramuscular methylcobalamin injections on chronic low back pain.

In a rigorously designed double-blinded, randomized controlled trial, 60 patients were divided into treatment and placebo groups.

We observed significant improvements in pain and disability scores among those receiving methylcobalamin compared to the placebo.

Additionally, the treatment was found to be safe, with only minor side effects reported.
Read More
8
Vitamin B complex aids back pain relief
We examined how well celecoxib and a combined vitamin B complex worked for people experiencing lower back pain, comparing them with meloxicam.

Our findings indicated that celecoxib, especially when paired with Neuromultivit (a vitamin B complex), showed improved effectiveness in relieving both acute and chronic back pain.

Interestingly, while meloxicam offered similar initial pain relief, celecoxib was found to be superior for long-term recovery and quality of life improvements.

This suggests that adding vitamin B to treatment could enhance outcomes for those suffering from chronic lower back pain.
Read More

Most Useful Reviews

7.5
Back pain reduced
31 people found this helpful
After learning to crush this product and mix it with yogurt, I noticed dramatic results. The probiotics increased absorption and within 45 minutes, my back pain was halved. I’m a bit concerned about the silica in it, but I plan to stock up on this product.
Read More
9
Pain relief solution
Vitamin B is my salvation for muscle pain. I ordered two jars at once.
Read More
9
No more back pain
A very effective supplement! I am sleeping better, I’m less irritable, and my back pain has vanished.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
  • All Researches
9
Combination therapy shows effectiveness
We set out to explore whether a rehabilitation program combined with specific supplements could effectively treat sciatica in young patients. Our study involved 128 individuals who were divided into three groups: one receiving both rehabilitation and supplements, one only with rehabilitation, and one with only supplements.

After treatment, the group with both rehabilitation and supplements showed significant improvement in pain relief and overall quality of life compared to the others. While the supplement-only group didn’t perform as well, this combination approach proved beneficial, particularly in reducing pain and enhancing stability.
Read More
We explored how effective vitamin B complex, alongside nonsteroidal anti-inflammatory drugs, is in treating back pain. Our study involved 70 patients divided into two groups, one receiving a vitamin B complex blend and the other a different pain relief combination.

Both groups showed improvement, but the first group experienced a clearer reduction in pain levels over time. By the third visit, they reported significantly less discomfort compared to the second group. Though both treatments were effective, the vitamin B complex showed a more pronounced impact on pain relief and patient satisfaction.
Read More
9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
9
Vitamin B complex effective for pain
We examined how Dolo-Neurobion, a blend of essential B vitamins and an analgesic, affects acute lumbosacral pain. In a study of 53 patients, we found that this treatment yielded good to excellent results in 77.4% of cases, while 15.1% experienced moderate effects. The approach combined initial parenteral dosing with continuation through oral intake, and any necessary antibiotics were also used. Most notably, we observed no significant side effects, making Dolo-Neurobion a promising option for back pain relief linked to pelvic organ issues.
Read More
8
Vitamin B12 aids postoperative recovery
We explored how combining dexamethasone with vitamin B12 could impact early recovery from back and leg pain after a specific spine surgery called percutaneous endoscopic interlaminar discectomy (PEID).

In our study, patients were divided into two groups: one received only the surgery, while the other got epidural injections of both medications during surgery.

Results showed that the combined treatment significantly reduced pain and inflammation, leading to better early recovery outcomes. This suggests that using this combination might be a great option for patients undergoing this type of surgery.
Read More

User Reviews

USERS' SCORE
Good
Based on 13 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Back pain reduced
31 people found this helpful
After learning to crush this product and mix it with yogurt, I noticed dramatic results. The probiotics increased absorption and within 45 minutes, my back pain was halved. I’m a bit concerned about the silica in it, but I plan to stock up on this product.
Read More
9
Pain relief solution
Vitamin B is my salvation for muscle pain. I ordered two jars at once.
Read More
9
No more back pain
A very effective supplement! I am sleeping better, I’m less irritable, and my back pain has vanished.
Read More
9
Muscle pain relief
Perfectly, I regularly take vitamin B complex as it does not accumulate in the body. It helps alleviate muscle pain, and I found the quality to be good. The capsules are large, yet they are easy to swallow.
Read More
9
Eased back pain
5 people found this helpful
I take this in spring and autumn when my osteochondrosis flares up. It alleviates spasms and discomfort in my spine, even pain radiating to my sternum. I also take magnesium glycinate alongside these.
Read More

Frequently Asked Questions

7.5
Joint pain relief
By the second or third day of use, the nocturnal aching in my right knee, which followed physical exertion and hadn’t subsided with ointments or heat treatments, stopped bothering me. I recommend it for joint pain!
7.5
Improved back pain
1 people found this helpful
I took it as instructed by my neurologist for back pain, and it improved significantly. There were no side effects, and I follow the dosage of one tablet per day.
9
Quick back pain relief
4 people found this helpful
After experiencing pain in my arm due to myalgia from exercise, I was surprised that it eased within 10 minutes of taking it. The effect seems consistent, so I believe it’s due to the vitamin B. It’s easier to take than the capsule version, and I will repurchase.
9
No more back pain
A very effective supplement! I am sleeping better, I’m less irritable, and my back pain has vanished.
9
Eased back pain
5 people found this helpful
I take this in spring and autumn when my osteochondrosis flares up. It alleviates spasms and discomfort in my spine, even pain radiating to my sternum. I also take magnesium glycinate alongside these.
7.5
Joint pain reduction
This is fantastic! My joint pain has reduced and I feel energised.
7.5
Tendon pain relief
It is advisable to have a vitamin B test before ordering and to follow a doctor's guidance, as deficiency affects the nervous system. I ordered it after my test due to pain in the tendons of my right arm. The quality is excellent compared to previous brands, though the taste is below average. Note it can change urine colour. Continued use and testing are essential; I hope it benefits you.
7.5
Reduced back pain
26 people found this helpful
A good form of Vitamin B complex at a reasonable price. I take it with magnesium citrate and it effectively addresses my back pain. I've noticed I'm less anxious, and the anti-stress effect is quite clear. If my feedback was useful, please click "yes".
7.5
Alleviated back pain
10 people found this helpful
I bought this B complex after reading reviews. It’s working well—no allergies noted. It has helped relieve my lower back pain. I take half a tablet due to the high vitamin dosage. I share it with my husband and girlfriend, which is quite economical. Be healthy!
8
Vitamin B aids back pain relief
We examined how vitamin B complex affects back pain by comparing two treatments: diclofenac alone versus diclofenac with B vitamins. In our randomized double-blind study with 123 participants suffering from acute lumbar pain, we found that those using B vitamins alongside diclofenac experienced better pain relief.

Notably, 30 patients in the combination group could stop treatment early due to symptom relief, compared to just 15 in the diclofenac-only group. This suggests that B vitamins not only improve outcomes but may also help reduce reliance on anti-inflammatory medications.
9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
9
Combination therapy shows effectiveness
We set out to explore whether a rehabilitation program combined with specific supplements could effectively treat sciatica in young patients. Our study involved 128 individuals who were divided into three groups: one receiving both rehabilitation and supplements, one only with rehabilitation, and one with only supplements.

After treatment, the group with both rehabilitation and supplements showed significant improvement in pain relief and overall quality of life compared to the others. While the supplement-only group didn’t perform as well, this combination approach proved beneficial, particularly in reducing pain and enhancing stability.
8
Combined therapy shows potential benefits
We initially aimed to explore whether combining diclofenac with thiamine, pyridoxine, and cyanocobalamin (B vitamins) could enhance pain relief for low back pain compared to diclofenac alone.

Our comprehensive review included randomized clinical trials and utilized a meta-analysis to analyze data from over 1,100 adults.

We observed that this combination therapy might significantly reduce treatment duration compared to diclofenac alone. However, we've concluded that the evidence isn't strong enough to recommend this approach universally, as more high-quality studies are necessary.

References

  1. He C, Li J, Hu W, Xiao B, Fan T, et al. Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial. J Orthop Surg Res. 2024;19:733. doi:10.1186/s13018-024-05210-z
  2. Scaturro D, Vitagliani F, Tomasello S, Sconza C, Respizzi S, et al. Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial. Medicina (Kaunas). 2023;59. doi:10.3390/medicina59122197
  3. Antonen EG, Kruchek MM, Nikitina MV. [Evaluation of the effectiveness of treatment of patients with nonspecific pain syndrome in the lower back with celecoxib and a combined preparation of B vitamins]. Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122:65. doi:10.17116/jnevro202212208165
  4. Barantsevich ER, Yakovlev AA, Gavrilova EA, Gavrichenko AV, Pushkarev MS, et al. [Study of the clinical efficacy and safety of the scheme of step therapy of nonsteroidal anti-inflammatory drugs and a complex of B vitamins in patients with low back pain]. Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121:67. doi:10.17116/jnevro202112110167
  5. Nava-Mesa MO, Aispuru Lanche GR. [Role of B vitamins, thiamine, pyridoxine, and cyanocobalamin in back pain and other musculoskeletal conditions: a narrative review]. Semergen. 2021;47:551. doi:10.1016/j.semerg.2021.01.010
  6. Calderon-Ospina CA, Nava-Mesa MO, Arbeláez Ariza CE. Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis. Pain Med. 2020;21:766. doi:10.1093/pm/pnz216
  7. Khabirov FA, Khaibullin TI, Granatov EV. [Evaluation of efficiency and safety of adding neuromultivit to basic therapy of vertebrogenic radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117:38. doi:10.17116/jnevro201711710138-43
  8. Chiu CK, Low TH, Tey YS, Singh VA, Shong HK. The efficacy and safety of intramuscular injections of methylcobalamin in patients with chronic nonspecific low back pain: a randomised controlled trial. Singapore Med J. 2011;52:868.
  9. Levin OS, Moseĭkin IA. [Vitamin B complex (milgamma) in the treatment of vertebrogenic lumbosacral radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2009;109:30.
  10. Mibielli MA, Geller M, Cohen JC, Goldberg SG, Cohen MT, et al. Diclofenac plus B vitamins versus diclofenac monotherapy in lumbago: the DOLOR study. Curr Med Res Opin. 2009;25:2589. doi:10.3111/13696990903246911
  11. Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000;4:53.
  12. Brüggemann G, Koehler CO, Koch EM. [Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study]. Klin Wochenschr. 1990;68:116.
  13. Kuhlwein A, Meyer HJ, Koehler CO. [Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes]. Klin Wochenschr. 1990;68:107.
  14. Kunt T. [Complaints in the lumbosacral region and their management with Dolo-Neurobion]. Fortschr Med. 1978;96:299.
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