Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (from Thiamin HCl) (Vitamin B-1)
100 mg
8333%
Riboflavin (Vitamin B-2)
100 mg
7692%
Niacin (Vitamin B-3) (as Niacinamide)
100 mg
625%
Vitamin B-6 (from Pyridoxine HCl)
100 mg
5882%
Folate
680 mcg DFE(400 mcg folic acid)
170%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4167%
Biotin
100 mcg
333%
Pantothenic Acid (from Calcium Pantothenate)
100 mg
2000%
Choline (from Choline Bitartrate)
35 mg
6%
Inositol
100 mg
PABA (Para-Aminobenzoic Acid)
10 mg

Top Medical Research Studies

9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Read More
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
Read More
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
Read More

Most Useful Reviews

7.5
No nausea experienced
3 people found this helpful
Good composition. The tablets are large but easy to swallow, and the smell is normal. I do not experience any feelings of nausea. I hope for good results as I have not been taking them long.
Read More
9
No nausea as directed
This is simply the best! The dose is perfect with sustained release, enhancing my energy levels and mental clarity. The size is manageable, easy to swallow, and I do not experience nausea as long as I take it after food.
Read More
9
No tummy aches
We all take this B-100 in the family. The size is suitable, not too big even for my children, who are better than average at swallowing vitamins. The ingredients are clean, and there is a great variety of B vitamins. We trust NOW for their quality and take them with meals, with no tummy aches or feelings of nausea experienced.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
  • All Researches
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
Read More
9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Read More
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
Read More
7
Pyridoxine shows potential for PONV
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.

Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 5 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
No nausea experienced
3 people found this helpful
Good composition. The tablets are large but easy to swallow, and the smell is normal. I do not experience any feelings of nausea. I hope for good results as I have not been taking them long.
Read More
9
No nausea as directed
This is simply the best! The dose is perfect with sustained release, enhancing my energy levels and mental clarity. The size is manageable, easy to swallow, and I do not experience nausea as long as I take it after food.
Read More
9
No tummy aches
We all take this B-100 in the family. The size is suitable, not too big even for my children, who are better than average at swallowing vitamins. The ingredients are clean, and there is a great variety of B vitamins. We trust NOW for their quality and take them with meals, with no tummy aches or feelings of nausea experienced.
Read More
0
Nausea after overdose
1 people found this helpful
I was aware that one tablet exceeded the upper limit, but I experienced palpitation and nausea immediately after ingestion. From now on, I will use a pill cutter to take a smaller dose gradually.
Read More
7.5
No nausea from brand
Probably the best I've tried. B-100 usually makes me feel nauseated and tastes peculiar, but this brand does not. The ingredient quality is excellent, leaving me feel energised and more alert after taking it. I would definitely choose this vitamin B-100 again.
Read More

Frequently Asked Questions

7.5
No nausea experienced
3 people found this helpful
Good composition. The tablets are large but easy to swallow, and the smell is normal. I do not experience any feelings of nausea. I hope for good results as I have not been taking them long.
9
No nausea as directed
This is simply the best! The dose is perfect with sustained release, enhancing my energy levels and mental clarity. The size is manageable, easy to swallow, and I do not experience nausea as long as I take it after food.
9
No tummy aches
We all take this B-100 in the family. The size is suitable, not too big even for my children, who are better than average at swallowing vitamins. The ingredients are clean, and there is a great variety of B vitamins. We trust NOW for their quality and take them with meals, with no tummy aches or feelings of nausea experienced.
0
Nausea after overdose
1 people found this helpful
I was aware that one tablet exceeded the upper limit, but I experienced palpitation and nausea immediately after ingestion. From now on, I will use a pill cutter to take a smaller dose gradually.
7
Pyridoxine shows potential for PONV
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.

Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.

References

  1. Zhang Q, Ye X, Shi S, Zhou S, Ma D, et al. Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial. Anesthesiology. 2024. doi:10.1097/ALN.0000000000005354
  2. Hayashi E, Matuura T, Takano J, Morofushi K, Toriizuka K, et al. Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi. Palliat Support Care. 2024;22:1511. doi:10.1017/S1478951524000415
  3. Saz-Leal P, Zamorano-Domínguez L, Frías J, Guerra P, Saura-Valls M, et al. Bioavailability of Cariban Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy. Drugs R D. 2023;23:185. doi:10.1007/s40268-023-00425-7
  4. Jayawardena R, Majeed S, Sooriyaarachchi P, Abeywarne U, Ranaweera P. The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis. Arch Gynecol Obstet. 2023;308:1075. doi:10.1007/s00404-023-06925-w
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