Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
9.5
We set out to investigate how vitamin D affects angina and exercise-induced ischemia in individuals with cardiac syndrome X who have low levels of this important vitamin. In our study, we treated participants with intramuscular injections of vitamin D3, administered every other week for two months, and monitored changes in their angina episodes as well as their exercise capacity.
After completing the treatment, we observed a noticeable rise in serum vitamin D levels among participants, bringing them into the normal range. More importantly, the frequency of angina episodes significantly decreased, indicating a direct correlation between vitamin D levels and angina symptoms. We also noted impressive increases in exercise duration and maximum work capacity, alongside significant improvements in indicators of cardiac stress, such as ST-segment depression.
These findings strongly suggest that vitamin D replacement can dramatically enhance the quality of life for those experiencing angina due to cardiac syndrome X. Our research highlights an often-overlooked solution to managing heart-related symptoms by simply addressing vitamin D deficiency.
After completing the treatment, we observed a noticeable rise in serum vitamin D levels among participants, bringing them into the normal range. More importantly, the frequency of angina episodes significantly decreased, indicating a direct correlation between vitamin D levels and angina symptoms. We also noted impressive increases in exercise duration and maximum work capacity, alongside significant improvements in indicators of cardiac stress, such as ST-segment depression.
These findings strongly suggest that vitamin D replacement can dramatically enhance the quality of life for those experiencing angina due to cardiac syndrome X. Our research highlights an often-overlooked solution to managing heart-related symptoms by simply addressing vitamin D deficiency.
Read More
8
We conducted a case-control study to explore the relationship between vitamin D levels and chronic stable angina. This involved comparing 42 patients suffering from chronic stable angina to 42 matched individuals without the condition, all sourced from Cairo University Hospitals.
Our findings revealed a stark contrast in vitamin D levels between the two groups. A staggering 78.6% of the angina patients were found to be severely deficient in vitamin D, compared to just 7.1% of the controls. This significant difference highlights the potential role vitamin D deficiency may play as a risk factor for chronic stable angina.
Moreover, our analysis indicated that increasing vitamin D levels could reduce the chances of developing angina. Specifically, for every 1 ng/ml increase in vitamin D, the likelihood of suffering from chronic stable angina decreased by 30%. This suggests that maintaining adequate vitamin D levels could be an important aspect of managing heart health.
However, it's important to note that while our research establishes a correlation, it does not specifically address any treatment efficacy of vitamin D supplements in patients with angina. Nonetheless, the association we observed prompts further investigation into how improving vitamin D status might benefit cardiovascular health.
Our findings revealed a stark contrast in vitamin D levels between the two groups. A staggering 78.6% of the angina patients were found to be severely deficient in vitamin D, compared to just 7.1% of the controls. This significant difference highlights the potential role vitamin D deficiency may play as a risk factor for chronic stable angina.
Moreover, our analysis indicated that increasing vitamin D levels could reduce the chances of developing angina. Specifically, for every 1 ng/ml increase in vitamin D, the likelihood of suffering from chronic stable angina decreased by 30%. This suggests that maintaining adequate vitamin D levels could be an important aspect of managing heart health.
However, it's important to note that while our research establishes a correlation, it does not specifically address any treatment efficacy of vitamin D supplements in patients with angina. Nonetheless, the association we observed prompts further investigation into how improving vitamin D status might benefit cardiovascular health.
Read More
7
We conducted a prospective case-control study to investigate the relationship between vitamin D levels and chronic stable angina. Our research involved 100 patients suffering from angina and a matched group of 100 individuals without the condition. We discovered alarming levels of vitamin D deficiency, particularly among those with angina.
Specifically, 75% of angina patients had deficient levels of vitamin D, defined as below 20 ng/mL. In contrast, only 10% of the control group fell into this category. This stark difference raises questions about the role of vitamin D as a potential factor influencing heart health.
While we found a clear correlation between low vitamin D levels and chronic stable angina, we didn’t establish that vitamin D is an independent risk factor. The study highlighted that increasing age correlates with declining vitamin D levels, which could add another layer to our understanding of cardiovascular health.
Essentially, while our findings don't definitively prove that vitamin D treatment can alleviate angina, they suggest a significant connection worth exploring further. It opens the door for considering vitamin D as a modifiable aspect of health in the context of heart disease.
Specifically, 75% of angina patients had deficient levels of vitamin D, defined as below 20 ng/mL. In contrast, only 10% of the control group fell into this category. This stark difference raises questions about the role of vitamin D as a potential factor influencing heart health.
While we found a clear correlation between low vitamin D levels and chronic stable angina, we didn’t establish that vitamin D is an independent risk factor. The study highlighted that increasing age correlates with declining vitamin D levels, which could add another layer to our understanding of cardiovascular health.
Essentially, while our findings don't definitively prove that vitamin D treatment can alleviate angina, they suggest a significant connection worth exploring further. It opens the door for considering vitamin D as a modifiable aspect of health in the context of heart disease.
Read More
Most Useful Reviews
9
Angina improvement
1 people found this helpful
I started taking 5,000 IU of Vitamin D daily after years on lower doses. My wife's 15-year battle with night sweats and depression has ended, and her energy has returned. For my angina, which lasted five years, it has also vanished in the last month. We think the higher dose of Vitamin D is responsible. We previously found only temporary relief.
Read More
7.5
Angina relief
I only take it during autumn and winter, and I've noticed a decrease in my angina. There is significant evidence supporting its benefits for the immune system and its ability to synthesise antibacterial peptides. I generally take 3 (5000) capsules weekly in winter, and I prefer Vitamin D3 as it is better absorbed.
Read More
7.5
Angina reduction
I take Vitamin D in autumn and winter, noticing a reduction in my angina during this time. It is essential for immune support, and I rely on it almost constantly. In winter, I consume 3 (5000) capsules weekly, favouring D3 for its superior absorption.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.6
- All Researches
9.5
We set out to investigate how vitamin D affects angina and exercise-induced ischemia in individuals with cardiac syndrome X who have low levels of this important vitamin. In our study, we treated participants with intramuscular injections of vitamin D3, administered every other week for two months, and monitored changes in their angina episodes as well as their exercise capacity.
After completing the treatment, we observed a noticeable rise in serum vitamin D levels among participants, bringing them into the normal range. More importantly, the frequency of angina episodes significantly decreased, indicating a direct correlation between vitamin D levels and angina symptoms. We also noted impressive increases in exercise duration and maximum work capacity, alongside significant improvements in indicators of cardiac stress, such as ST-segment depression.
These findings strongly suggest that vitamin D replacement can dramatically enhance the quality of life for those experiencing angina due to cardiac syndrome X. Our research highlights an often-overlooked solution to managing heart-related symptoms by simply addressing vitamin D deficiency.
After completing the treatment, we observed a noticeable rise in serum vitamin D levels among participants, bringing them into the normal range. More importantly, the frequency of angina episodes significantly decreased, indicating a direct correlation between vitamin D levels and angina symptoms. We also noted impressive increases in exercise duration and maximum work capacity, alongside significant improvements in indicators of cardiac stress, such as ST-segment depression.
These findings strongly suggest that vitamin D replacement can dramatically enhance the quality of life for those experiencing angina due to cardiac syndrome X. Our research highlights an often-overlooked solution to managing heart-related symptoms by simply addressing vitamin D deficiency.
Read More
8
We conducted a case-control study to explore the relationship between vitamin D levels and chronic stable angina. This involved comparing 42 patients suffering from chronic stable angina to 42 matched individuals without the condition, all sourced from Cairo University Hospitals.
Our findings revealed a stark contrast in vitamin D levels between the two groups. A staggering 78.6% of the angina patients were found to be severely deficient in vitamin D, compared to just 7.1% of the controls. This significant difference highlights the potential role vitamin D deficiency may play as a risk factor for chronic stable angina.
Moreover, our analysis indicated that increasing vitamin D levels could reduce the chances of developing angina. Specifically, for every 1 ng/ml increase in vitamin D, the likelihood of suffering from chronic stable angina decreased by 30%. This suggests that maintaining adequate vitamin D levels could be an important aspect of managing heart health.
However, it's important to note that while our research establishes a correlation, it does not specifically address any treatment efficacy of vitamin D supplements in patients with angina. Nonetheless, the association we observed prompts further investigation into how improving vitamin D status might benefit cardiovascular health.
Our findings revealed a stark contrast in vitamin D levels between the two groups. A staggering 78.6% of the angina patients were found to be severely deficient in vitamin D, compared to just 7.1% of the controls. This significant difference highlights the potential role vitamin D deficiency may play as a risk factor for chronic stable angina.
Moreover, our analysis indicated that increasing vitamin D levels could reduce the chances of developing angina. Specifically, for every 1 ng/ml increase in vitamin D, the likelihood of suffering from chronic stable angina decreased by 30%. This suggests that maintaining adequate vitamin D levels could be an important aspect of managing heart health.
However, it's important to note that while our research establishes a correlation, it does not specifically address any treatment efficacy of vitamin D supplements in patients with angina. Nonetheless, the association we observed prompts further investigation into how improving vitamin D status might benefit cardiovascular health.
Read More
8
We studied the effects of vitamin D3, combined with calcium, on patients suffering from chronic coronary heart disease, particularly those experiencing angina. Our research involved 130 patients divided into two groups: one receiving standard treatment and the other receiving calcium-D3 alongside their regular medications.
Both groups showed a positive shift, particularly in the reduction of angina severity and the need for nitroglycerin. Importantly, we observed no negative impact from calcium-D3 on the severity of coronary heart disease. However, some side effects were noted, particularly in those taking furosemide and hydrochlorothiazide, leading to adjustments in their medication.
Overall, this study indicates that while the addition of calcium-D3 did not harm treatment outcomes for angina, it also highlights that we cannot definitively attribute improvements solely to vitamin D3. Instead, it appears to be safely included as part of a broader treatment strategy without undermining the effectiveness of existing therapies.
Both groups showed a positive shift, particularly in the reduction of angina severity and the need for nitroglycerin. Importantly, we observed no negative impact from calcium-D3 on the severity of coronary heart disease. However, some side effects were noted, particularly in those taking furosemide and hydrochlorothiazide, leading to adjustments in their medication.
Overall, this study indicates that while the addition of calcium-D3 did not harm treatment outcomes for angina, it also highlights that we cannot definitively attribute improvements solely to vitamin D3. Instead, it appears to be safely included as part of a broader treatment strategy without undermining the effectiveness of existing therapies.
Read More
7
We conducted a prospective case-control study to investigate the relationship between vitamin D levels and chronic stable angina. Our research involved 100 patients suffering from angina and a matched group of 100 individuals without the condition. We discovered alarming levels of vitamin D deficiency, particularly among those with angina.
Specifically, 75% of angina patients had deficient levels of vitamin D, defined as below 20 ng/mL. In contrast, only 10% of the control group fell into this category. This stark difference raises questions about the role of vitamin D as a potential factor influencing heart health.
While we found a clear correlation between low vitamin D levels and chronic stable angina, we didn’t establish that vitamin D is an independent risk factor. The study highlighted that increasing age correlates with declining vitamin D levels, which could add another layer to our understanding of cardiovascular health.
Essentially, while our findings don't definitively prove that vitamin D treatment can alleviate angina, they suggest a significant connection worth exploring further. It opens the door for considering vitamin D as a modifiable aspect of health in the context of heart disease.
Specifically, 75% of angina patients had deficient levels of vitamin D, defined as below 20 ng/mL. In contrast, only 10% of the control group fell into this category. This stark difference raises questions about the role of vitamin D as a potential factor influencing heart health.
While we found a clear correlation between low vitamin D levels and chronic stable angina, we didn’t establish that vitamin D is an independent risk factor. The study highlighted that increasing age correlates with declining vitamin D levels, which could add another layer to our understanding of cardiovascular health.
Essentially, while our findings don't definitively prove that vitamin D treatment can alleviate angina, they suggest a significant connection worth exploring further. It opens the door for considering vitamin D as a modifiable aspect of health in the context of heart disease.
Read More
7
We examined the relationship between vitamin D levels and a condition known as cardiac X syndrome, which is characterized by typical chest pain and evidence of myocardial ischemia despite normal coronary angiogram results. In this study, we compared serum vitamin D levels in 66 patients with syndrome X to 47 healthy individuals, looking for any noticeable differences.
Our analysis revealed that patients with syndrome X had significantly lower vitamin D levels compared to the control group. Specifically, the average vitamin D level in patients was just 6 ng/ml, whereas the controls averaged 11.9 ng/ml. Additionally, we observed higher levels of parathormone and hsCRP, indicating there may be a link between vitamin D deficiency and increased inflammation in these patients.
While these findings suggest that vitamin D deficiency could be a risk factor for syndrome X, we didn’t directly address how vitamin D treatment for angina might affect this condition. As such, this study does not fully clarify the efficacy of vitamin D treatment specifically for alleviating angina symptoms.
Our analysis revealed that patients with syndrome X had significantly lower vitamin D levels compared to the control group. Specifically, the average vitamin D level in patients was just 6 ng/ml, whereas the controls averaged 11.9 ng/ml. Additionally, we observed higher levels of parathormone and hsCRP, indicating there may be a link between vitamin D deficiency and increased inflammation in these patients.
While these findings suggest that vitamin D deficiency could be a risk factor for syndrome X, we didn’t directly address how vitamin D treatment for angina might affect this condition. As such, this study does not fully clarify the efficacy of vitamin D treatment specifically for alleviating angina symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Angina improvement
1 people found this helpful
I started taking 5,000 IU of Vitamin D daily after years on lower doses. My wife's 15-year battle with night sweats and depression has ended, and her energy has returned. For my angina, which lasted five years, it has also vanished in the last month. We think the higher dose of Vitamin D is responsible. We previously found only temporary relief.
Read More
7.5
Angina relief
I only take it during autumn and winter, and I've noticed a decrease in my angina. There is significant evidence supporting its benefits for the immune system and its ability to synthesise antibacterial peptides. I generally take 3 (5000) capsules weekly in winter, and I prefer Vitamin D3 as it is better absorbed.
Read More
7.5
Angina reduction
I take Vitamin D in autumn and winter, noticing a reduction in my angina during this time. It is essential for immune support, and I rely on it almost constantly. In winter, I consume 3 (5000) capsules weekly, favouring D3 for its superior absorption.
Read More
7.5
Angina management
I take this drug in courses after experiencing angina flare-ups, and it helps maintain my thyroid health. I am very satisfied with its effectiveness.
Read More
Frequently Asked Questions
9
Angina improvement
1 people found this helpful
I started taking 5,000 IU of Vitamin D daily after years on lower doses. My wife's 15-year battle with night sweats and depression has ended, and her energy has returned. For my angina, which lasted five years, it has also vanished in the last month. We think the higher dose of Vitamin D is responsible. We previously found only temporary relief.
7.5
Angina relief
I only take it during autumn and winter, and I've noticed a decrease in my angina. There is significant evidence supporting its benefits for the immune system and its ability to synthesise antibacterial peptides. I generally take 3 (5000) capsules weekly in winter, and I prefer Vitamin D3 as it is better absorbed.
7.5
Angina reduction
I take Vitamin D in autumn and winter, noticing a reduction in my angina during this time. It is essential for immune support, and I rely on it almost constantly. In winter, I consume 3 (5000) capsules weekly, favouring D3 for its superior absorption.
7.5
Angina management
I take this drug in courses after experiencing angina flare-ups, and it helps maintain my thyroid health. I am very satisfied with its effectiveness.
8
We conducted a case-control study to explore the relationship between vitamin D levels and chronic stable angina. This involved comparing 42 patients suffering from chronic stable angina to 42 matched individuals without the condition, all sourced from Cairo University Hospitals.
Our findings revealed a stark contrast in vitamin D levels between the two groups. A staggering 78.6% of the angina patients were found to be severely deficient in vitamin D, compared to just 7.1% of the controls. This significant difference highlights the potential role vitamin D deficiency may play as a risk factor for chronic stable angina.
Moreover, our analysis indicated that increasing vitamin D levels could reduce the chances of developing angina. Specifically, for every 1 ng/ml increase in vitamin D, the likelihood of suffering from chronic stable angina decreased by 30%. This suggests that maintaining adequate vitamin D levels could be an important aspect of managing heart health.
However, it's important to note that while our research establishes a correlation, it does not specifically address any treatment efficacy of vitamin D supplements in patients with angina. Nonetheless, the association we observed prompts further investigation into how improving vitamin D status might benefit cardiovascular health.
Our findings revealed a stark contrast in vitamin D levels between the two groups. A staggering 78.6% of the angina patients were found to be severely deficient in vitamin D, compared to just 7.1% of the controls. This significant difference highlights the potential role vitamin D deficiency may play as a risk factor for chronic stable angina.
Moreover, our analysis indicated that increasing vitamin D levels could reduce the chances of developing angina. Specifically, for every 1 ng/ml increase in vitamin D, the likelihood of suffering from chronic stable angina decreased by 30%. This suggests that maintaining adequate vitamin D levels could be an important aspect of managing heart health.
However, it's important to note that while our research establishes a correlation, it does not specifically address any treatment efficacy of vitamin D supplements in patients with angina. Nonetheless, the association we observed prompts further investigation into how improving vitamin D status might benefit cardiovascular health.
9.5
We set out to investigate how vitamin D affects angina and exercise-induced ischemia in individuals with cardiac syndrome X who have low levels of this important vitamin. In our study, we treated participants with intramuscular injections of vitamin D3, administered every other week for two months, and monitored changes in their angina episodes as well as their exercise capacity.
After completing the treatment, we observed a noticeable rise in serum vitamin D levels among participants, bringing them into the normal range. More importantly, the frequency of angina episodes significantly decreased, indicating a direct correlation between vitamin D levels and angina symptoms. We also noted impressive increases in exercise duration and maximum work capacity, alongside significant improvements in indicators of cardiac stress, such as ST-segment depression.
These findings strongly suggest that vitamin D replacement can dramatically enhance the quality of life for those experiencing angina due to cardiac syndrome X. Our research highlights an often-overlooked solution to managing heart-related symptoms by simply addressing vitamin D deficiency.
After completing the treatment, we observed a noticeable rise in serum vitamin D levels among participants, bringing them into the normal range. More importantly, the frequency of angina episodes significantly decreased, indicating a direct correlation between vitamin D levels and angina symptoms. We also noted impressive increases in exercise duration and maximum work capacity, alongside significant improvements in indicators of cardiac stress, such as ST-segment depression.
These findings strongly suggest that vitamin D replacement can dramatically enhance the quality of life for those experiencing angina due to cardiac syndrome X. Our research highlights an often-overlooked solution to managing heart-related symptoms by simply addressing vitamin D deficiency.
7
We set out to explore how vitamin D therapy might affect patients dealing with ischemic heart disease (IHD) and experiencing vitamin D deficiency or insufficiency. Our study included a group of 40 female patients, all of whom were undergoing treatment for heart issues, such as chronic angina. They received two significant injections of vitamin D, and we measured their endothelial function before treatment and again one month after the second injection.
After the therapy, we observed a notable improvement in certain aspects of vascular function, particularly a measurable increase in flow-mediated dilatation (FMD). Specifically, FMD rose from an average of 1.96% to 4.65%, which was statistically significant. However, when diving deeper into the data, we found that the improvements in FMD were not linked to the levels of vitamin D in the blood, indicating that the treatment might not have a direct connection to alleviating angina symptoms.
In conclusion, while we noted improvements in endothelial function post-treatment, the lack of significant correlation between vitamin D levels and angina means we may need to research further in controlled studies with more participants. This investigation opens the door to understanding how vitamin D affects heart health but leaves crucial questions unanswered regarding its role in directly easing angina symptoms.
After the therapy, we observed a notable improvement in certain aspects of vascular function, particularly a measurable increase in flow-mediated dilatation (FMD). Specifically, FMD rose from an average of 1.96% to 4.65%, which was statistically significant. However, when diving deeper into the data, we found that the improvements in FMD were not linked to the levels of vitamin D in the blood, indicating that the treatment might not have a direct connection to alleviating angina symptoms.
In conclusion, while we noted improvements in endothelial function post-treatment, the lack of significant correlation between vitamin D levels and angina means we may need to research further in controlled studies with more participants. This investigation opens the door to understanding how vitamin D affects heart health but leaves crucial questions unanswered regarding its role in directly easing angina symptoms.
References
- Raslan E, Soliman SSA, Nour ZA, Ahmed D, Saad NES. Association of Vitamin D Deficiency with Chronic Stable Angina: A Case Control Study. High Blood Press Cardiovasc Prev. 2019;26:77. doi:10.1007/s40292-018-0295-7
- Raina AH, Allai MS, Shah ZA, Changal KH, Raina MA, et al. Association of Low Levels of Vitamin D with Chronic Stable Angina: A Prospective Case-Control Study. N Am J Med Sci. 2016;8:143. doi:10.4103/1947-2714.179130
- Turhan Caglar FN, Ungan I, Ksanski V, Opan S, Çiftçi S, et al. Evaluation of serum vitamin D levels in patients with X syndrome. Eur Rev Med Pharmacol Sci. 2016;20:1155.
- Hashemi SM, Mokhtari SM, Sadeghi M, Foroozan R, Safari M. Effect of vitamin D therapy on endothelial function in ischemic heart disease female patients with vitamin D deficiency or insufficiency: A primary report. ARYA Atheroscler. 2015;11:54.
- Andishmand A, Ansari Z, Soltani MH, Mirshamsi H, Raafat S. Vitamin D replacement therapy in patients with cardiac syndrome X. Perfusion. 2015;30:60. doi:10.1177/0267659114526629
- Gordina MA, Orlovskiĭ VF. [Effect of vitamin D correction on insulin resistance in patients with coronary heart disease and metabolic syndrome]. Georgian Med News. 2014.
- Bazhenov AN, Kol'tsova IV, Iaroshenko GA. [Interaction of calcium drug and vitamin D3 with some medicines used in coronary heart disease therapy]. Klin Med (Mosk). 2008;86:51.
