Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
USERS' SCORE
Moderately Good
Based on 20 Reviews
7.8
Supplement Facts
Serving Size:   1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%

Top Medical Research Studies

8
Vitamin D deficiency affects symptoms
We aimed to understand how vitamin D deficiency (VDD) might influence symptoms like chest pain, anxiety, and fatigue in people living with coronary artery disease (CAD). In our investigation, we collected data from 90 CAD patients, focusing on their vitamin D levels and experiences with these symptoms.

The findings were quite revealing. A significant 80% of the participants were found to have low vitamin D levels. Interestingly, we discovered that lower vitamin D levels were linked to increased chest pain and heightened anxiety and fatigue. Specifically, there were strong negative relationships noted: as vitamin D levels dropped, chest pain, anxiety, and fatigue scores rose.

This suggests that addressing vitamin D deficiency might be an important step for managing cardiac-related symptoms in patients with CAD. As this connection unfolds, it seems valuable for healthcare providers to monitor vitamin D levels in CAD patients and consider interventions to correct deficiencies.
Read More
We investigated how vitamin D influences chest pain in individuals experiencing vaccine-related myocarditis after receiving the BNT162b2 COVID-19 vaccine. Our study involved analyzing vitamin D levels, immune profiles, and genetic factors in 60 patients who suffered from this condition.

A significant finding was that a high percentage of these patients, about 73.3%, were found to have low vitamin D levels. Particularly concerning was the observation that those patients who presented with chest pain were more likely to be vitamin D deficient. We also found that lower vitamin D levels were linked to higher peak levels of cardiac troponin T, a marker indicating heart stress.

Additionally, we explored genetic factors and found that certain genetic variations could either increase or increase the potential risk related to vitamin D status. These findings suggest that hypovitaminosis D may exacerbate inflammation and activate specific immune cells, leading to symptoms like chest pain.

Overall, our research supports the idea that improving vitamin D status could be crucial in reducing vaccine-related myocarditis and associated chest pain, revealing a path for potential preventive measures and treatment strategies.
Read More
9
Impact of Vitamin D on Chest Pain
We observed a case involving a middle-aged woman who reported persistent chest pain after starting a new weight training routine. Initially, her pain was localized around the right chest area, making it hard to pinpoint the exact cause. Standard examinations, including ultrasound and X-rays, didn’t uncover any issues, leading to further investigation with an MRI.

The MRI revealed swelling in the sternum, indicating a sternal stress fracture. In response to this finding, the patient was prescribed calcium and vitamin D supplements and advised to rest for six weeks. Following her recovery period, she gradually resumed her activities and was pleased to find herself pain-free after four months.

While it’s clear that vitamin D was part of her treatment regimen, we can only speculate on its specific role in alleviating her chest pain because it was combined with calcium. This means we can't definitively state that vitamin D alone was effective in this case.

Overall, this case serves as an interesting insight into the management of stress fractures in the chest area, showing the importance of proper supplementation and rest in recovery.
Read More

Most Useful Reviews

7.5
Joint pain relief
12 people found this helpful
This vitamin has greatly improved my health. After two months of taking it, I found it easier to wake up, had more energy, and my joint pain vanished, which was attributed to a vitamin D deficiency. I’ve experienced no side effects, and I'm very satisfied with this product.
Read More
9
Back pain alleviated
6 people found this helpful
After experiencing low vitamin D levels post-pregnancy, my level rose significantly after two months on these 5000 IU vitamins. Consequently, my lower back and joint pain subsided. I highly recommend this product!
Read More
9
Joint pain disappearance
2 people found this helpful
I have experienced joint pain in my fingers and believed a D3 deficiency was the cause. Since I started taking it, the pain has completely disappeared, alleviating my worries about rheumatism.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
  • All Researches
We investigated the effectiveness of vitamin D in relieving chest pain associated with a complex case of adult-onset hypophosphatemic osteomalacia (HO) in a 47-year-old woman suffering from Sjogren’s syndrome. In this case, the patient experienced progressively worsening pain in the chest, back, and legs, along with muscle weakness, raising questions about the underlying causes and appropriate treatment options.

After examining lab results, radiographic findings, and pathology, the diagnosis of adult-onset HO was confirmed. The treatment regimen included not only vitamin D but also alkalinization, steroids, neutral phosphate, and calcium supplements. Although the combination of treatments resulted in improved outcomes—such as pain relief and increased serum phosphorus levels—it’s difficult to isolate the effect of vitamin D specifically on chest pain, as it was one part of a broader therapeutic approach.

This case highlights the challenges of diagnosing and treating complex conditions like hypophosphatemic osteomalacia, particularly when associated with autoimmune disorders like Sjogren's syndrome. It underscores the importance of considering various factors and the potential interplay of treatments in managing such cases.
Read More
9
Impact of Vitamin D on Chest Pain
We observed a case involving a middle-aged woman who reported persistent chest pain after starting a new weight training routine. Initially, her pain was localized around the right chest area, making it hard to pinpoint the exact cause. Standard examinations, including ultrasound and X-rays, didn’t uncover any issues, leading to further investigation with an MRI.

The MRI revealed swelling in the sternum, indicating a sternal stress fracture. In response to this finding, the patient was prescribed calcium and vitamin D supplements and advised to rest for six weeks. Following her recovery period, she gradually resumed her activities and was pleased to find herself pain-free after four months.

While it’s clear that vitamin D was part of her treatment regimen, we can only speculate on its specific role in alleviating her chest pain because it was combined with calcium. This means we can't definitively state that vitamin D alone was effective in this case.

Overall, this case serves as an interesting insight into the management of stress fractures in the chest area, showing the importance of proper supplementation and rest in recovery.
Read More
We investigated how vitamin D influences chest pain in individuals experiencing vaccine-related myocarditis after receiving the BNT162b2 COVID-19 vaccine. Our study involved analyzing vitamin D levels, immune profiles, and genetic factors in 60 patients who suffered from this condition.

A significant finding was that a high percentage of these patients, about 73.3%, were found to have low vitamin D levels. Particularly concerning was the observation that those patients who presented with chest pain were more likely to be vitamin D deficient. We also found that lower vitamin D levels were linked to higher peak levels of cardiac troponin T, a marker indicating heart stress.

Additionally, we explored genetic factors and found that certain genetic variations could either increase or increase the potential risk related to vitamin D status. These findings suggest that hypovitaminosis D may exacerbate inflammation and activate specific immune cells, leading to symptoms like chest pain.

Overall, our research supports the idea that improving vitamin D status could be crucial in reducing vaccine-related myocarditis and associated chest pain, revealing a path for potential preventive measures and treatment strategies.
Read More
8
Vitamin D deficiency affects symptoms
We aimed to understand how vitamin D deficiency (VDD) might influence symptoms like chest pain, anxiety, and fatigue in people living with coronary artery disease (CAD). In our investigation, we collected data from 90 CAD patients, focusing on their vitamin D levels and experiences with these symptoms.

The findings were quite revealing. A significant 80% of the participants were found to have low vitamin D levels. Interestingly, we discovered that lower vitamin D levels were linked to increased chest pain and heightened anxiety and fatigue. Specifically, there were strong negative relationships noted: as vitamin D levels dropped, chest pain, anxiety, and fatigue scores rose.

This suggests that addressing vitamin D deficiency might be an important step for managing cardiac-related symptoms in patients with CAD. As this connection unfolds, it seems valuable for healthcare providers to monitor vitamin D levels in CAD patients and consider interventions to correct deficiencies.
Read More
8
Vitamin D3's Heart Impact
We explored how vitamin D3 plays a role in managing chest pain, particularly in relation to various cardiovascular health indicators. Our investigation emphasizes the significance of optimal vitamin D3 dosage; notably, 400 IU proves beneficial for heart health. However, we also highlighted the potential risks associated with higher doses, such as the commonly used 2000 IU, which can be detrimental.

While vitamin D3 shows promise for overall wellness, its direct impact on alleviating chest pain remains less clear. The study examines visible and invisible changes on the face that suggest cardiovascular issues, with a focus on areas like the eyebrows and left upper lip. However, there’s no conclusive evidence to suggest a marked improvement in chest pain solely from vitamin D3 treatment.

Overall, while maintaining adequate vitamin D3 levels is crucial for heart health, relying on it exclusively to relieve chest pain doesn't seem fully supported by our findings. The emphasis is on a comprehensive approach, combining dietary supplements with other medical interventions for heart conditions.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 20 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Joint pain relief
12 people found this helpful
This vitamin has greatly improved my health. After two months of taking it, I found it easier to wake up, had more energy, and my joint pain vanished, which was attributed to a vitamin D deficiency. I’ve experienced no side effects, and I'm very satisfied with this product.
Read More
9
Back pain alleviated
6 people found this helpful
After experiencing low vitamin D levels post-pregnancy, my level rose significantly after two months on these 5000 IU vitamins. Consequently, my lower back and joint pain subsided. I highly recommend this product!
Read More
9
Joint pain disappearance
2 people found this helpful
I have experienced joint pain in my fingers and believed a D3 deficiency was the cause. Since I started taking it, the pain has completely disappeared, alleviating my worries about rheumatism.
Read More
9
Tooth pain reduced
1 people found this helpful
I had severe toothache attributed to vitamin D deficiency. After taking 5,000 IU, the pain started to fade within two days. A lower dose wouldn't suffice.
Read More
9
Pain completely vanished
1 people found this helpful
After increasing my vitamin D3 intake to 20,000 IU daily for my cervical herniated disc, I was astonished to find that the pain, including chest pain, had vanished overnight. Initially, movements caused sharp discomfort, and I feared I might become depressed due to my injury. Now, even after reducing my dose to 15,000 IU, the pain has not returned.
Read More

Frequently Asked Questions

9
Tooth pain reduced
1 people found this helpful
I had severe toothache attributed to vitamin D deficiency. After taking 5,000 IU, the pain started to fade within two days. A lower dose wouldn't suffice.
9
Pain completely vanished
1 people found this helpful
After increasing my vitamin D3 intake to 20,000 IU daily for my cervical herniated disc, I was astonished to find that the pain, including chest pain, had vanished overnight. Initially, movements caused sharp discomfort, and I feared I might become depressed due to my injury. Now, even after reducing my dose to 15,000 IU, the pain has not returned.
7.5
Back pain improved
2 people found this helpful
After suffering from back pain for years, a doctor recommended vitamin D. After three months of use, my pain diminished significantly, and I felt more energetic and in a better mood during winter.
9
Chest pain relief
Using this supplement for some time has notably alleviated my chest pain, which used to be tight and severe. I'm relieved and grateful for the results I've seen.
9
Chest pain improved
1 people found this helpful
After suffering from bone pain, I've noticed significant improvement thanks to this supplement. I recommend having an analysis first to determine the right dosage for your needs. Thankfully, I experienced no adverse reactions, and my chest pain has shown noticeable improvement.
9
Joint pain disappearance
2 people found this helpful
I have experienced joint pain in my fingers and believed a D3 deficiency was the cause. Since I started taking it, the pain has completely disappeared, alleviating my worries about rheumatism.
7
Knee pain improvement
1 people found this helpful
My elderly relatives suffered from knee degeneration. After starting D3 alongside their usual supplements, their knee pain improved significantly when rising.
9
Back pain alleviated
6 people found this helpful
After experiencing low vitamin D levels post-pregnancy, my level rose significantly after two months on these 5000 IU vitamins. Consequently, my lower back and joint pain subsided. I highly recommend this product!
0
Joint pain noted
1 people found this helpful
I mistakenly took this without tests and ended up with excess vitamin D, leading to joint pain and chest pain, as well as high blood pressure and kidney issues. Thankfully, I'm fine now but caution that attention to health is crucial.
7.5
Pain improvement noted
So far, I've been taking one softgel every third day for three weeks, alongside Strontium. I'm noticing improvements; my fingers and ankles feel better, and the pain, including chest pain, is lessening significantly, which I hope continues.
We investigated how vitamin D influences chest pain in individuals experiencing vaccine-related myocarditis after receiving the BNT162b2 COVID-19 vaccine. Our study involved analyzing vitamin D levels, immune profiles, and genetic factors in 60 patients who suffered from this condition.

A significant finding was that a high percentage of these patients, about 73.3%, were found to have low vitamin D levels. Particularly concerning was the observation that those patients who presented with chest pain were more likely to be vitamin D deficient. We also found that lower vitamin D levels were linked to higher peak levels of cardiac troponin T, a marker indicating heart stress.

Additionally, we explored genetic factors and found that certain genetic variations could either increase or increase the potential risk related to vitamin D status. These findings suggest that hypovitaminosis D may exacerbate inflammation and activate specific immune cells, leading to symptoms like chest pain.

Overall, our research supports the idea that improving vitamin D status could be crucial in reducing vaccine-related myocarditis and associated chest pain, revealing a path for potential preventive measures and treatment strategies.
8
Vitamin D deficiency affects symptoms
We aimed to understand how vitamin D deficiency (VDD) might influence symptoms like chest pain, anxiety, and fatigue in people living with coronary artery disease (CAD). In our investigation, we collected data from 90 CAD patients, focusing on their vitamin D levels and experiences with these symptoms.

The findings were quite revealing. A significant 80% of the participants were found to have low vitamin D levels. Interestingly, we discovered that lower vitamin D levels were linked to increased chest pain and heightened anxiety and fatigue. Specifically, there were strong negative relationships noted: as vitamin D levels dropped, chest pain, anxiety, and fatigue scores rose.

This suggests that addressing vitamin D deficiency might be an important step for managing cardiac-related symptoms in patients with CAD. As this connection unfolds, it seems valuable for healthcare providers to monitor vitamin D levels in CAD patients and consider interventions to correct deficiencies.
We explored the intriguing link between vitamin D levels, calcium intake, and non-cardiac chest pain (NCCP), particularly focusing on psychological factors like anxiety. In this case-control study, we compared 40 individuals experiencing NCCP with 40 healthy controls matched by age and gender.

Our findings revealed that those suffering from NCCP had notably higher anxiety and depression scores, alongside lower levels of vitamin D and dietary calcium compared to their healthier counterparts. Notably, the presence of NCCP was strongly associated with increased anxiety, showing an odds ratio of 1.40.

What's more, we observed a striking correlation: the anxiety scores were inversely related to both vitamin D levels and calcium intake. In simple terms, lower levels of vitamin D were connected to higher anxiety scores among participants with NCCP.

While these results spotlight an important relationship, it's essential to remember that the study doesn't isolate the effects of vitamin D from psychological factors. This means we should look at these findings with caution—they suggest a potential link but don't conclusively prove that increasing vitamin D directly alleviates NCCP.

Overall, our study encourages a broader consideration of anxiety and vitamin D deficiency when addressing non-cardiac chest pain, highlighting a potential path for future research and treatments.
We investigated the effectiveness of vitamin D in relieving chest pain associated with a complex case of adult-onset hypophosphatemic osteomalacia (HO) in a 47-year-old woman suffering from Sjogren’s syndrome. In this case, the patient experienced progressively worsening pain in the chest, back, and legs, along with muscle weakness, raising questions about the underlying causes and appropriate treatment options.

After examining lab results, radiographic findings, and pathology, the diagnosis of adult-onset HO was confirmed. The treatment regimen included not only vitamin D but also alkalinization, steroids, neutral phosphate, and calcium supplements. Although the combination of treatments resulted in improved outcomes—such as pain relief and increased serum phosphorus levels—it’s difficult to isolate the effect of vitamin D specifically on chest pain, as it was one part of a broader therapeutic approach.

This case highlights the challenges of diagnosing and treating complex conditions like hypophosphatemic osteomalacia, particularly when associated with autoimmune disorders like Sjogren's syndrome. It underscores the importance of considering various factors and the potential interplay of treatments in managing such cases.
8
Vitamin D3's Heart Impact
We explored how vitamin D3 plays a role in managing chest pain, particularly in relation to various cardiovascular health indicators. Our investigation emphasizes the significance of optimal vitamin D3 dosage; notably, 400 IU proves beneficial for heart health. However, we also highlighted the potential risks associated with higher doses, such as the commonly used 2000 IU, which can be detrimental.

While vitamin D3 shows promise for overall wellness, its direct impact on alleviating chest pain remains less clear. The study examines visible and invisible changes on the face that suggest cardiovascular issues, with a focus on areas like the eyebrows and left upper lip. However, there’s no conclusive evidence to suggest a marked improvement in chest pain solely from vitamin D3 treatment.

Overall, while maintaining adequate vitamin D3 levels is crucial for heart health, relying on it exclusively to relieve chest pain doesn't seem fully supported by our findings. The emphasis is on a comprehensive approach, combining dietary supplements with other medical interventions for heart conditions.
9
Impact of Vitamin D on Chest Pain
We observed a case involving a middle-aged woman who reported persistent chest pain after starting a new weight training routine. Initially, her pain was localized around the right chest area, making it hard to pinpoint the exact cause. Standard examinations, including ultrasound and X-rays, didn’t uncover any issues, leading to further investigation with an MRI.

The MRI revealed swelling in the sternum, indicating a sternal stress fracture. In response to this finding, the patient was prescribed calcium and vitamin D supplements and advised to rest for six weeks. Following her recovery period, she gradually resumed her activities and was pleased to find herself pain-free after four months.

While it’s clear that vitamin D was part of her treatment regimen, we can only speculate on its specific role in alleviating her chest pain because it was combined with calcium. This means we can't definitively state that vitamin D alone was effective in this case.

Overall, this case serves as an interesting insight into the management of stress fractures in the chest area, showing the importance of proper supplementation and rest in recovery.
8
Calcium and vitamin D3 treatment effective
We explored the case of a 25-year-old woman who experienced chest pain and ECG changes typically associated with a heart attack. After undergoing cardiac catheterization, doctors found her coronary arteries to be normal but noted impaired left ventricular performance.

Further tests revealed she had primary hypoparathyroidism leading to low calcium levels, or hypocalcemia. To address this, she was treated with calcium and vitamin D3 supplements, which significantly improved her condition and alleviated her symptoms.

Although she eventually remained symptom-free, some ECG repolarization disturbances persisted. This case provides important insights into how low calcium levels can mimic acute myocardial infarction and highlights the effective role of vitamin D3 and calcium in alleviating related chest pain.

References

  1. Tsang HW, Chua GT, Tung KTS, Wong RSM, Tsao SSL, et al. The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis. Front Immunol. 2025;16:1501609. doi:10.3389/fimmu.2025.1501609
  2. Khater WA, Alfarkh MA, Allnoubani A. The Association Between Vitamin D Level and Chest Pain, Anxiety, and Fatigue in Patients With Coronary Artery Disease. Clin Nurs Res. 2023;32:639. doi:10.1177/10547738221126325
  3. Alkhatatbeh MJ, Abdul-Razzak KK, Amara NA, Al-Jarrah M. Non-cardiac Chest Pain and Anxiety: A Possible Link to Vitamin D and Calcium. J Clin Psychol Med Settings. 2019;26:194. doi:10.1007/s10880-018-9579-2
  4. Tsuchiya M, Takaki R, Kobayashi F, Nagasaka T, Shindo K, et al. [Multiple pseudofractures due to Fanconi's syndrome associated with Wilson's disease]. Rinsho Shinkeigaku. 2017;57:527. doi:10.5692/clinicalneurol.cn-000953
  5. Shen G, Zhang Y, Hu S, Liu B, Kuang A. Adult-onset hypophosphatemic osteomalacia associated with Sjogren syndrome: Clinical case report. Medicine (Baltimore). 2017;96:e6493. doi:10.1097/MD.0000000000006493
  6. Lee J, Fields KB. Sternal stress fracture in a middle-aged woman. BMJ Case Rep. 2017;2017. doi:10.1136/bcr-2016-218203
  7. Omura Y, Jones MK, Duvvi H, Shimotsuura Y, Ohki M, et al. Non-invasive quick diagnosis of cardiovascular problems from visible and invisible abnormal changes with increased cardiac troponin I appearing on cardiovascular representation areas of the eyebrows, left upper lip, etc. of the face & hands: beneficial manual stimulation of hands for acute anginal chest pain, and important factors in safe, effective treatment. Acupunct Electrother Res. 2014;39:135.
  8. Lehmann G, Deisenhofer I, Ndrepepa G, Schmitt C. ECG changes in a 25-year-old woman with hypocalcemia due to hypoparathyroidism. Hypocalcemia mimicking acute myocardial infarction. Chest. 2000;118:260.
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