5/6/2025
Last update
5/6/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Questionable
Based on 27 Reviews
5.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
5
We explored how vitamin D levels affect nausea and other premenstrual symptoms (PMS) while considering the influence of genetics. Our study involved 716 women between the ages of 20 and 29, who provided blood samples to measure their vitamin D status and completed questionnaires about their PMS experiences.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
Read More
Most Useful Reviews
9
No nausea benefit
18 people found this helpful
The pill is small, odourless, and does not cause nausea. I find one a week sufficient for my needs. According to my doctor, it's best taken after a fatty meal, such as eggs or avocado, for better absorption.
Read More
10
No nausea reported
6 people found this helpful
These tiny gel caps are easy to swallow and were recommended for their potency. My husband takes them in the morning on an empty stomach without experiencing any nausea or upset stomach.
Read More
9
Post-illness recovery
This dosage is ideal after an illness. I take it daily and will order more. It doesn't cause nausea, and I find the vitamins to be great for the price.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
- All Researches
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
5
We explored how vitamin D levels affect nausea and other premenstrual symptoms (PMS) while considering the influence of genetics. Our study involved 716 women between the ages of 20 and 29, who provided blood samples to measure their vitamin D status and completed questionnaires about their PMS experiences.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
Read More
User Reviews
USERS' SCORE
Questionable
Based on 27 Reviews
5.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
No nausea benefit
18 people found this helpful
The pill is small, odourless, and does not cause nausea. I find one a week sufficient for my needs. According to my doctor, it's best taken after a fatty meal, such as eggs or avocado, for better absorption.
Read More
10
No nausea reported
6 people found this helpful
These tiny gel caps are easy to swallow and were recommended for their potency. My husband takes them in the morning on an empty stomach without experiencing any nausea or upset stomach.
Read More
9
Post-illness recovery
This dosage is ideal after an illness. I take it daily and will order more. It doesn't cause nausea, and I find the vitamins to be great for the price.
Read More
0
Nausea and insomnia
I take vitamin D every other day. It caused me nausea, a loss of appetite, and insomnia. I will attempt to take it weekly instead.
Read More
0
Nausea and breathlessness
This did not work for me; I experienced nausea and shortness of breath.
Read More
Frequently Asked Questions
6
Energy boost
33 people found this helpful
Very excellent for psychological effects, mood, and activity. I recommend taking it with two tablespoons of original olive oil on an empty stomach or with lunch. It worked wonders from the first use. Initially, there was a slight nausea, but then it became a great source of energy.
7.5
Energy boost
4 people found this helpful
Taking two tablespoons of olive oil with it on an empty stomach or lunch works wonders. From the first use, I experienced a bit of nausea, but then it provided a burst of energy.
0
Shock to system
After taking this 5000 IU pill, I experienced nausea and blurred vision. A second dose caused the same effects. While many have positive experiences, I reacted poorly to this high dose, which felt shocking to my body. It would be wise to try a lower IU.
0
Careful dosage
I encountered nausea and headaches from daily use of this product, likely due to overdosing. Caution is advised with high doses.
7.5
Consult when deficient
We purchase this to maintain a healthy immune system. If you're deficient in D3, see a doctor for dosage. Nausea and other symptoms can occur from improper use. It's best taken with calcium for absorption.
0
Doctor's advice
1 people found this helpful
I take this on my doctor's recommendation for COVID-19 prevention, as my friend used it successfully. However, it can cause nausea if not taken with food.
2
Slight nausea
The price is good, and the small capsules are easy to swallow. However, the dosage is very high. After a couple of weeks, I noticed slight nausea, so I switched to taking 1 capsule every other day, which resolved the nausea.
0
Be cautious
Not suitable for everyone. I managed to consume only about 10 capsules intermittently due to terrible nausea. I discovered online that the maximum daily dosage for a healthy adult is 4000 IU. I subsequently tested low for vitamin D and will consult a doctor for the appropriate dosage, as excess vitamin D is worse than a deficiency. Always read up and test your levels. With COVID, I took 400 IU daily without side effects. Take care.
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
5
We explored how vitamin D levels affect nausea and other premenstrual symptoms (PMS) while considering the influence of genetics. Our study involved 716 women between the ages of 20 and 29, who provided blood samples to measure their vitamin D status and completed questionnaires about their PMS experiences.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
References
- Koch KL, Parkman HP, Yates KP, Van Natta ML, Grover M, et al. Low Vitamin D Levels in Patients with Symptoms of Gastroparesis: Relationships with Nausea and Vomiting, Gastric Emptying and Gastric Myoelectrical Activity. Dig Dis Sci. 2024;69:2904. 10.1007/s10620-024-08520-8
- Jarosz AC, Noori D, Zeitoun T, Garcia-Bailo B, El-Sohemy A. Variation in the vitamin D receptor gene, plasma 25-hydroxyvitamin D, and risk of premenstrual symptoms. Genes Nutr. 2021;16:15. 10.1186/s12263-021-00696-2
