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SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
9
Vitamin D3 supplementation effective
Vitamin D in blood serum and chronic pancreatitis.
Highly relevant to research question
We explored the relationship between vitamin D levels and chronic pancreatitis, a condition often characterized by malabsorption and malnutrition. In a study involving fifty patients with chronic pancreatitis and a control group of twenty individuals without gastrointestinal diseases, we measured the vitamin D levels in their blood serum.
Our findings revealed that a significant number of patients with chronic pancreatitis—about 60-80%—had notably low vitamin D levels. This is concerning, as low vitamin D can contribute to various health issues. To address this, we administered a high dose of 1.5 million IU of vitamin D3 daily to those with low levels for a duration of 24 weeks. After this treatment, we reassessed the participants' vitamin D levels.
The results were promising; vitamin D levels in patients improved significantly following supplementation. However, while we observed effective correction of vitamin D deficiency, more research is essential to determine potential long-term benefits, particularly regarding its role in fibrogenesis. Our study's limitations include the relatively small number of subjects, which suggests the need for broader studies in the future.
Our findings revealed that a significant number of patients with chronic pancreatitis—about 60-80%—had notably low vitamin D levels. This is concerning, as low vitamin D can contribute to various health issues. To address this, we administered a high dose of 1.5 million IU of vitamin D3 daily to those with low levels for a duration of 24 weeks. After this treatment, we reassessed the participants' vitamin D levels.
The results were promising; vitamin D levels in patients improved significantly following supplementation. However, while we observed effective correction of vitamin D deficiency, more research is essential to determine potential long-term benefits, particularly regarding its role in fibrogenesis. Our study's limitations include the relatively small number of subjects, which suggests the need for broader studies in the future.
Read More
7
Assessment of vitamin D3 supplementation
Fat-Soluble Vitamin Supplementation Using Liposomes, Cyclodextrins, or Medium-Chain Triglycerides in Cystic Fibrosis: A Randomized Controlled Trial.
Moderate relevance to pancreatitis effects
In a quest to tackle fat-soluble vitamin deficiencies—common among patients with pancreatic issues such as cystic fibrosis—we embarked on a study comparing various methods of vitamin D3 supplementation. Over three months, we tested the effectiveness of liposomal and cyclodextrin formulations against medium-chain triglycerides (MCTs) in a group of 75 pancreatic-insufficient cystic fibrosis patients.
Our findings revealed intriguing results. While the study showed promising improvements in vitamin A and D3 levels with certain formulations, we noticed that those taking cyclodextrins experienced a more significant increase in vitamin D3 levels compared to the MCT group. Specifically, participants using cyclodextrins saw an average rise of 9.0 ng/mL in vitamin D3, suggesting this method could enhance vitamin D3 bioavailability.
However, it’s important to note that while there was a positive trend, the overall impact on direct pancreatitis effects remains unclear due to the presence of multiple vitamins and other factors in our approach. Consequently, we advocate for further research to better disentangle these effects and clarify vitamin D3's benefits specifically related to pancreatic health.
Our findings revealed intriguing results. While the study showed promising improvements in vitamin A and D3 levels with certain formulations, we noticed that those taking cyclodextrins experienced a more significant increase in vitamin D3 levels compared to the MCT group. Specifically, participants using cyclodextrins saw an average rise of 9.0 ng/mL in vitamin D3, suggesting this method could enhance vitamin D3 bioavailability.
However, it’s important to note that while there was a positive trend, the overall impact on direct pancreatitis effects remains unclear due to the presence of multiple vitamins and other factors in our approach. Consequently, we advocate for further research to better disentangle these effects and clarify vitamin D3's benefits specifically related to pancreatic health.
Read More
8
Vitamin D3 in pancreatitis treatment
Ayurvedic Treatment Protocol for Hereditary Pancreatitis: A Case Report Demonstrating Disease Arrestation.
Combination approach limits evaluation
We explored the potential benefits of vitamin D3 in a treatment protocol for hereditary pancreatitis (HP). In a notable case involving a 14-year-old boy, we implemented an Ayurvedic treatment protocol (ATP) that not only utilized specific herbo-mineral formulations but also included vitamin D3 supplementation.
Although the boy had experienced frequent and severe episodes of pancreatitis under conventional treatment, we observed significant improvements after commencing the ATP in February 2022. He reported feeling better overall and returned to a normal routine without discomfort.
Importantly, we noted that after a year of following this treatment approach, the disease progression appeared to have arrested. While the specific impact of vitamin D3 alone cannot be isolated due to this multi-faceted treatment, it was part of an overall strategy that effectively reduced the size of the pancreatic duct and improved the patient's quality of life.
Our findings suggest that vitamin D3, when combined with other Ayurvedic strategies, may contribute to better management of hereditary pancreatitis. However, we acknowledge the need for further studies to clearly define its role and understand how it works in conjunction with other treatments.
Although the boy had experienced frequent and severe episodes of pancreatitis under conventional treatment, we observed significant improvements after commencing the ATP in February 2022. He reported feeling better overall and returned to a normal routine without discomfort.
Importantly, we noted that after a year of following this treatment approach, the disease progression appeared to have arrested. While the specific impact of vitamin D3 alone cannot be isolated due to this multi-faceted treatment, it was part of an overall strategy that effectively reduced the size of the pancreatic duct and improved the patient's quality of life.
Our findings suggest that vitamin D3, when combined with other Ayurvedic strategies, may contribute to better management of hereditary pancreatitis. However, we acknowledge the need for further studies to clearly define its role and understand how it works in conjunction with other treatments.
Read More
Most Useful Reviews
8
Bone health complications
In acute vitamin D deficiency, symptoms such as weight loss, insomnia, frequent bone fractures, and deterioration of vision can arise before more severe issues like rickets or osteoporosis. I also experienced complications like lupus erythematosus, pancreatitis, enterocolitis, and chronic gastritis, which underscored the importance of addressing vitamin deficiencies.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
9
Vitamin D3 supplementation effective
Vitamin D in blood serum and chronic pancreatitis.
Highly relevant to research question
We explored the relationship between vitamin D levels and chronic pancreatitis, a condition often characterized by malabsorption and malnutrition. In a study involving fifty patients with chronic pancreatitis and a control group of twenty individuals without gastrointestinal diseases, we measured the vitamin D levels in their blood serum.
Our findings revealed that a significant number of patients with chronic pancreatitis—about 60-80%—had notably low vitamin D levels. This is concerning, as low vitamin D can contribute to various health issues. To address this, we administered a high dose of 1.5 million IU of vitamin D3 daily to those with low levels for a duration of 24 weeks. After this treatment, we reassessed the participants' vitamin D levels.
The results were promising; vitamin D levels in patients improved significantly following supplementation. However, while we observed effective correction of vitamin D deficiency, more research is essential to determine potential long-term benefits, particularly regarding its role in fibrogenesis. Our study's limitations include the relatively small number of subjects, which suggests the need for broader studies in the future.
Our findings revealed that a significant number of patients with chronic pancreatitis—about 60-80%—had notably low vitamin D levels. This is concerning, as low vitamin D can contribute to various health issues. To address this, we administered a high dose of 1.5 million IU of vitamin D3 daily to those with low levels for a duration of 24 weeks. After this treatment, we reassessed the participants' vitamin D levels.
The results were promising; vitamin D levels in patients improved significantly following supplementation. However, while we observed effective correction of vitamin D deficiency, more research is essential to determine potential long-term benefits, particularly regarding its role in fibrogenesis. Our study's limitations include the relatively small number of subjects, which suggests the need for broader studies in the future.
Read More
8
Vitamin D3 in pancreatitis treatment
Ayurvedic Treatment Protocol for Hereditary Pancreatitis: A Case Report Demonstrating Disease Arrestation.
Combination approach limits evaluation
We explored the potential benefits of vitamin D3 in a treatment protocol for hereditary pancreatitis (HP). In a notable case involving a 14-year-old boy, we implemented an Ayurvedic treatment protocol (ATP) that not only utilized specific herbo-mineral formulations but also included vitamin D3 supplementation.
Although the boy had experienced frequent and severe episodes of pancreatitis under conventional treatment, we observed significant improvements after commencing the ATP in February 2022. He reported feeling better overall and returned to a normal routine without discomfort.
Importantly, we noted that after a year of following this treatment approach, the disease progression appeared to have arrested. While the specific impact of vitamin D3 alone cannot be isolated due to this multi-faceted treatment, it was part of an overall strategy that effectively reduced the size of the pancreatic duct and improved the patient's quality of life.
Our findings suggest that vitamin D3, when combined with other Ayurvedic strategies, may contribute to better management of hereditary pancreatitis. However, we acknowledge the need for further studies to clearly define its role and understand how it works in conjunction with other treatments.
Although the boy had experienced frequent and severe episodes of pancreatitis under conventional treatment, we observed significant improvements after commencing the ATP in February 2022. He reported feeling better overall and returned to a normal routine without discomfort.
Importantly, we noted that after a year of following this treatment approach, the disease progression appeared to have arrested. While the specific impact of vitamin D3 alone cannot be isolated due to this multi-faceted treatment, it was part of an overall strategy that effectively reduced the size of the pancreatic duct and improved the patient's quality of life.
Our findings suggest that vitamin D3, when combined with other Ayurvedic strategies, may contribute to better management of hereditary pancreatitis. However, we acknowledge the need for further studies to clearly define its role and understand how it works in conjunction with other treatments.
Read More
7
Assessment of vitamin D3 supplementation
Fat-Soluble Vitamin Supplementation Using Liposomes, Cyclodextrins, or Medium-Chain Triglycerides in Cystic Fibrosis: A Randomized Controlled Trial.
Moderate relevance to pancreatitis effects
In a quest to tackle fat-soluble vitamin deficiencies—common among patients with pancreatic issues such as cystic fibrosis—we embarked on a study comparing various methods of vitamin D3 supplementation. Over three months, we tested the effectiveness of liposomal and cyclodextrin formulations against medium-chain triglycerides (MCTs) in a group of 75 pancreatic-insufficient cystic fibrosis patients.
Our findings revealed intriguing results. While the study showed promising improvements in vitamin A and D3 levels with certain formulations, we noticed that those taking cyclodextrins experienced a more significant increase in vitamin D3 levels compared to the MCT group. Specifically, participants using cyclodextrins saw an average rise of 9.0 ng/mL in vitamin D3, suggesting this method could enhance vitamin D3 bioavailability.
However, it’s important to note that while there was a positive trend, the overall impact on direct pancreatitis effects remains unclear due to the presence of multiple vitamins and other factors in our approach. Consequently, we advocate for further research to better disentangle these effects and clarify vitamin D3's benefits specifically related to pancreatic health.
Our findings revealed intriguing results. While the study showed promising improvements in vitamin A and D3 levels with certain formulations, we noticed that those taking cyclodextrins experienced a more significant increase in vitamin D3 levels compared to the MCT group. Specifically, participants using cyclodextrins saw an average rise of 9.0 ng/mL in vitamin D3, suggesting this method could enhance vitamin D3 bioavailability.
However, it’s important to note that while there was a positive trend, the overall impact on direct pancreatitis effects remains unclear due to the presence of multiple vitamins and other factors in our approach. Consequently, we advocate for further research to better disentangle these effects and clarify vitamin D3's benefits specifically related to pancreatic health.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8
Bone health complications
In acute vitamin D deficiency, symptoms such as weight loss, insomnia, frequent bone fractures, and deterioration of vision can arise before more severe issues like rickets or osteoporosis. I also experienced complications like lupus erythematosus, pancreatitis, enterocolitis, and chronic gastritis, which underscored the importance of addressing vitamin deficiencies.
Read More
