Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.5
USERS' SCORE
Good
Based on 8 Reviews
8.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
9
Vitamin D improves EPTB treatment outcomes
We assessed vitamin D levels in patients with extrapulmonary tuberculosis (EPTB) and evaluated the effects of vitamin D3 supplementation on their treatment.
In our study, 47 EPTB patients received vitamin D3 or standard anti-TB treatment alone. We found that vitamin D levels were much lower in EPTB patients compared to healthy controls.
Those receiving vitamin D3 showed improvements, such as better weight gain, higher albumin and hemoglobin levels, and reduced inflammation markers, suggesting that vitamin D supplementation can enhance anti-TB therapy.
In our study, 47 EPTB patients received vitamin D3 or standard anti-TB treatment alone. We found that vitamin D levels were much lower in EPTB patients compared to healthy controls.
Those receiving vitamin D3 showed improvements, such as better weight gain, higher albumin and hemoglobin levels, and reduced inflammation markers, suggesting that vitamin D supplementation can enhance anti-TB therapy.
Read More
9
Vitamin D possibly protects against TB
We investigated the role of vitamin D in preventing active tuberculosis (TB) in individuals closely associated with TB patients. In a year-long study involving 20 high-risk contacts, we monitored vitamin D levels and related immune markers.
Interestingly, none of the participants developed active TB, even though they were frequently exposed to highly infectious individuals. This suggests that adequate vitamin D levels could play a protective role against the disease. However, we noticed a decrease in other immune markers over time, implying a potential decline in bacterial exposure.
While our findings indicate that maintaining optimal vitamin D levels may offer some defense, a more extensive follow-up of individuals with severe vitamin D deficiency would help clarify its effectiveness further.
Interestingly, none of the participants developed active TB, even though they were frequently exposed to highly infectious individuals. This suggests that adequate vitamin D levels could play a protective role against the disease. However, we noticed a decrease in other immune markers over time, implying a potential decline in bacterial exposure.
While our findings indicate that maintaining optimal vitamin D levels may offer some defense, a more extensive follow-up of individuals with severe vitamin D deficiency would help clarify its effectiveness further.
Read More
7
We examined whether vitamin D supplementation could enhance treatment responses in pulmonary tuberculosis patients with different vitamin D receptor gene polymorphisms.
Over two years, 73 patients received an 800 IU daily dose for eight weeks, significantly boosting their serum vitamin D levels.
Interestingly, those with the FF genotype of the Fok1 polymorphism showed a more positive response to vitamin D treatment. In contrast, other polymorphisms did not show statistically significant improvements.
Thus, vitamin D may be beneficial when tailored to genetic factors in TB patients.
Over two years, 73 patients received an 800 IU daily dose for eight weeks, significantly boosting their serum vitamin D levels.
Interestingly, those with the FF genotype of the Fok1 polymorphism showed a more positive response to vitamin D treatment. In contrast, other polymorphisms did not show statistically significant improvements.
Thus, vitamin D may be beneficial when tailored to genetic factors in TB patients.
Read More
Most Useful Reviews
9
Supports immune function
Vitamin D is key for the immune system, supporting both innate and acquired immunity. It aids in producing antibodies that are crucial in fighting tuberculosis. Additionally, it plays a role in the formation of blood cells. It also supports skin health and helps manage autoimmune reactions, making it an essential vitamin for overall well-being.
Read More
7.5
Supports vitamin absorption
Thanks for the great vitamins, I've been taking them for the second week. My vitamin D was very low at 19, so I was prescribed 5000 IU. I've been buying vitamins for quite a while. They help me feel normal. Before starting aquadetrim, I found other vitamins unsuitable. Vitamin D is best taken with calcium, phosphorus, magnesium, Omega-3 fatty acids, and vitamin K2. Beware that iron, high doses of vitamin E, certain anti-tuberculosis drugs, and some other medications can disrupt absorption. It's important to take B vitamins to counteract side effects.
Read More
7.5
Boosts energy levels
This excellent vitamin raises blood vitamin D levels. I knew vitamin D deficiency could result in rickets due to its role in calcium-phosphorus metabolism. However, it's also linked to conditions like obesity, autoimmune diseases, and infections like tuberculosis. After two months of taking capsules, my vitamin D levels rose significantly from 19 to 60. I felt more energetic but noticed no weight change yet. It's important to take it with fatty foods for better absorption.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.5
- All Researches
9.5
We explored a series involving 130 patients with spinal tuberculosis (TB) who faced neurological issues and vitamin D deficiencies. Following surgery and the administration of anti-TB drugs alongside vitamin D for 12 months, results showed remarkable recovery. Remarkably, all patients regained normal motor function and had high fusion rates.
While these findings are promising, they still highlight the need for further research to confirm vitamin D's overall effectiveness and safety as an adjunct in spinal TB treatment. Surgery and anti-TB medication remain critical aspects of the treatment protocol.
While these findings are promising, they still highlight the need for further research to confirm vitamin D's overall effectiveness and safety as an adjunct in spinal TB treatment. Surgery and anti-TB medication remain critical aspects of the treatment protocol.
Read More
9
Vitamin D improves EPTB treatment outcomes
We assessed vitamin D levels in patients with extrapulmonary tuberculosis (EPTB) and evaluated the effects of vitamin D3 supplementation on their treatment.
In our study, 47 EPTB patients received vitamin D3 or standard anti-TB treatment alone. We found that vitamin D levels were much lower in EPTB patients compared to healthy controls.
Those receiving vitamin D3 showed improvements, such as better weight gain, higher albumin and hemoglobin levels, and reduced inflammation markers, suggesting that vitamin D supplementation can enhance anti-TB therapy.
In our study, 47 EPTB patients received vitamin D3 or standard anti-TB treatment alone. We found that vitamin D levels were much lower in EPTB patients compared to healthy controls.
Those receiving vitamin D3 showed improvements, such as better weight gain, higher albumin and hemoglobin levels, and reduced inflammation markers, suggesting that vitamin D supplementation can enhance anti-TB therapy.
Read More
9
Vitamin D possibly protects against TB
We investigated the role of vitamin D in preventing active tuberculosis (TB) in individuals closely associated with TB patients. In a year-long study involving 20 high-risk contacts, we monitored vitamin D levels and related immune markers.
Interestingly, none of the participants developed active TB, even though they were frequently exposed to highly infectious individuals. This suggests that adequate vitamin D levels could play a protective role against the disease. However, we noticed a decrease in other immune markers over time, implying a potential decline in bacterial exposure.
While our findings indicate that maintaining optimal vitamin D levels may offer some defense, a more extensive follow-up of individuals with severe vitamin D deficiency would help clarify its effectiveness further.
Interestingly, none of the participants developed active TB, even though they were frequently exposed to highly infectious individuals. This suggests that adequate vitamin D levels could play a protective role against the disease. However, we noticed a decrease in other immune markers over time, implying a potential decline in bacterial exposure.
While our findings indicate that maintaining optimal vitamin D levels may offer some defense, a more extensive follow-up of individuals with severe vitamin D deficiency would help clarify its effectiveness further.
Read More
7
We examined whether vitamin D supplementation could enhance treatment responses in pulmonary tuberculosis patients with different vitamin D receptor gene polymorphisms.
Over two years, 73 patients received an 800 IU daily dose for eight weeks, significantly boosting their serum vitamin D levels.
Interestingly, those with the FF genotype of the Fok1 polymorphism showed a more positive response to vitamin D treatment. In contrast, other polymorphisms did not show statistically significant improvements.
Thus, vitamin D may be beneficial when tailored to genetic factors in TB patients.
Over two years, 73 patients received an 800 IU daily dose for eight weeks, significantly boosting their serum vitamin D levels.
Interestingly, those with the FF genotype of the Fok1 polymorphism showed a more positive response to vitamin D treatment. In contrast, other polymorphisms did not show statistically significant improvements.
Thus, vitamin D may be beneficial when tailored to genetic factors in TB patients.
Read More
7
Micronutrient supplements improve HIV health
We analyzed the effects of micronutrient supplementation, including vitamin D, on clinical outcomes for adults living with HIV undergoing antiretroviral therapy (HAART). While vitamin D increased blood levels significantly, it didn't show a meaningful impact on CD4 counts overall.
Interestingly, vitamin D appears to have potential benefits for preventing sputum-smear-positive tuberculosis. Likewise, selenium and vitamin E supplementation may help with anemia. However, zinc showed limited effectiveness on CD4 counts and other measures.
Overall, these findings suggest that micronutrients like zinc and vitamin D can support immune health for many individuals with HIV on HAART.
Interestingly, vitamin D appears to have potential benefits for preventing sputum-smear-positive tuberculosis. Likewise, selenium and vitamin E supplementation may help with anemia. However, zinc showed limited effectiveness on CD4 counts and other measures.
Overall, these findings suggest that micronutrients like zinc and vitamin D can support immune health for many individuals with HIV on HAART.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports immune function
Vitamin D is key for the immune system, supporting both innate and acquired immunity. It aids in producing antibodies that are crucial in fighting tuberculosis. Additionally, it plays a role in the formation of blood cells. It also supports skin health and helps manage autoimmune reactions, making it an essential vitamin for overall well-being.
Read More
7.5
Supports vitamin absorption
Thanks for the great vitamins, I've been taking them for the second week. My vitamin D was very low at 19, so I was prescribed 5000 IU. I've been buying vitamins for quite a while. They help me feel normal. Before starting aquadetrim, I found other vitamins unsuitable. Vitamin D is best taken with calcium, phosphorus, magnesium, Omega-3 fatty acids, and vitamin K2. Beware that iron, high doses of vitamin E, certain anti-tuberculosis drugs, and some other medications can disrupt absorption. It's important to take B vitamins to counteract side effects.
Read More
7.5
Boosts energy levels
This excellent vitamin raises blood vitamin D levels. I knew vitamin D deficiency could result in rickets due to its role in calcium-phosphorus metabolism. However, it's also linked to conditions like obesity, autoimmune diseases, and infections like tuberculosis. After two months of taking capsules, my vitamin D levels rose significantly from 19 to 60. I felt more energetic but noticed no weight change yet. It's important to take it with fatty foods for better absorption.
Read More
7.5
Unique vitamin-hormone benefits
Vitamin D serves as both a vitamin and a hormone. It helps prevent fractures and boosts resistance to tuberculosis. Unfortunately, my tests revealed a vitamin D level of just 21. Since adequate sunlight exposure is limited, I take this supplement, which aids calcium absorption and overall metabolism. I advise taking one capsule every two to three days with meals, preferably alongside NOW Vitamin A and Calcium Supplements. Overall, it’s beneficial for health!
Read More
7.5
Enhances immunity year-round
This D3 supplement is wonderful! Nutritionists recommend taking it regularly to boost immunity, especially in fall and winter. It's a misconception that sunlight provides adequate vitamin D. A deficiency can lead to bronchitis, asthma, and tuberculosis, making consistent vitamin D intake essential for health.
Read More
Frequently Asked Questions
7.5
Boosts energy levels
This excellent vitamin raises blood vitamin D levels. I knew vitamin D deficiency could result in rickets due to its role in calcium-phosphorus metabolism. However, it's also linked to conditions like obesity, autoimmune diseases, and infections like tuberculosis. After two months of taking capsules, my vitamin D levels rose significantly from 19 to 60. I felt more energetic but noticed no weight change yet. It's important to take it with fatty foods for better absorption.
7.5
Enhances immunity year-round
This D3 supplement is wonderful! Nutritionists recommend taking it regularly to boost immunity, especially in fall and winter. It's a misconception that sunlight provides adequate vitamin D. A deficiency can lead to bronchitis, asthma, and tuberculosis, making consistent vitamin D intake essential for health.
7.5
Supports vitamin absorption
Thanks for the great vitamins, I've been taking them for the second week. My vitamin D was very low at 19, so I was prescribed 5000 IU. I've been buying vitamins for quite a while. They help me feel normal. Before starting aquadetrim, I found other vitamins unsuitable. Vitamin D is best taken with calcium, phosphorus, magnesium, Omega-3 fatty acids, and vitamin K2. Beware that iron, high doses of vitamin E, certain anti-tuberculosis drugs, and some other medications can disrupt absorption. It's important to take B vitamins to counteract side effects.
9
Supports immune function
Vitamin D is key for the immune system, supporting both innate and acquired immunity. It aids in producing antibodies that are crucial in fighting tuberculosis. Additionally, it plays a role in the formation of blood cells. It also supports skin health and helps manage autoimmune reactions, making it an essential vitamin for overall well-being.
7.5
Prevents serious ailments
Vitamin D3 is crucial for proper bone growth and development. Its deficiency in children can lead to rickets, while in adults, it can cause osteoporosis. Vitamin D is important in treating diseases like coronavirus and tuberculosis. A deficiency can cause muscle weakness, depression, irritability, and dental issues. This product has excellent quality, containing vegetable oil, vitamin D3, and other beneficial ingredients.
7.5
Unique vitamin-hormone benefits
Vitamin D serves as both a vitamin and a hormone. It helps prevent fractures and boosts resistance to tuberculosis. Unfortunately, my tests revealed a vitamin D level of just 21. Since adequate sunlight exposure is limited, I take this supplement, which aids calcium absorption and overall metabolism. I advise taking one capsule every two to three days with meals, preferably alongside NOW Vitamin A and Calcium Supplements. Overall, it’s beneficial for health!
7.5
Essential for all ages
In our current situation, it's crucial to highlight the importance of vitamin D not only for children but also for older adults. This vitamin, often called the 'vitamin from Coronavirus', helps combat fractures and increases resistance to tuberculosis. Ensuring adequate vitamin D intake is essential as it influences many aspects of health.
References
- Bavi H, Hosseini SA, Ekrami A, Alavi SM, Malehi AS. Effect of Vitamin D Supplementation on the Treatment of Pulmonary Tuberculosis Patients in Different Polymorphisms of the Vitamin D Receptor. Adv Biomed Res. 2024;13:102. 10.4103/abr.abr_76_24
- Meng J, Li X, Xiong Y, Wu Y, Liu P, et al. The role of vitamin D in the prevention and treatment of tuberculosis: a meta-analysis of randomized controlled trials. Infection. 2024. 10.1007/s15010-024-02446-z
- Okoka EM, Kuyebi MA, Oyadiran OT, Okusanya TR, Onaku E, et al. Effect of Micronutrients on HIV-Related Clinical Outcomes Among Adults Living With HIV on Antiretroviral Therapy: Systematic Review and Meta-analysis. Nutr Rev. 2024. 10.1093/nutrit/nuae171
- Rathored J, Sharma SK, Banavaliker JN, Sreenivas V, Srivastava AK. Response to treatment and low serum vitamin D levels in North Indian patients with treatment-naive category I and multi-drug resistant pulmonary tuberculosis. Ann Med. 2024;56:2407066. 10.1080/07853890.2024.2407066
- Zhou Y, Wu Q, Wang F, Chen S, Zhang Y, et al. Association of variant vitamin statuses and tuberculosis development: a systematic review and meta-analysis. Ann Med. 2024;56:2396566. 10.1080/07853890.2024.2396566
- Dholakia Y, Govekar L, Mistry N. Long-term follow-up of contacts of drug-resistant tuberculosis cases in high-burden areas of Mumbai, India. Indian J Tuberc. 2024;71 Suppl 1:S86. 10.1016/j.ijtb.2024.04.002
- Semita IN, Fatmawati H, Munawir A, Juliasih NN. Complete neurological recovery of spinal tuberculosis after spinal surgery and vitamin D supplementary: A case series. Int J Surg Case Rep. 2024;122:110053. 10.1016/j.ijscr.2024.110053
- Eletreby R, Elsharkawy A, Mohamed R, Hamed M, Kamal Ibrahim E, et al. Prevalence of vitamin D deficiency and the effect of vitamin D3 supplementation on response to anti-tuberculosis therapy in patients with extrapulmonary tuberculosis. BMC Infect Dis. 2024;24:681. 10.1186/s12879-024-09367-0
- Reddy DVS, Sofi HS, Roy T, Verma S, Washimkar KR, et al. Macrophage-targeted versus free calcitriol as host-directed adjunct therapy against Mycobacterium tuberculosis infection in mice is bacteriostatic and mitigates tissue pathology. Tuberculosis (Edinb). 2024;148:102536. 10.1016/j.tube.2024.102536
- Chandra H, Rahman A, Yadav P, Maurya G, Kumar Shukla S. Effect of adjunct Vitamin D treatment in vitamin D deficient pulmonary tuberculosis patients: A randomized, double blind, active controlled clinical trial. Indian J Tuberc. 2024;71:170. 10.1016/j.ijtb.2023.04.026
- Panda S, Tiwari A, Kumar V, Luthra K, Kumar K, et al. Protective Role of Vitamin D Against Development of Active Tuberculosis in Close Household Contacts of Pulmonary Tuberculosis Patients: A Prospective Cohort Study. Indian J Clin Biochem. 2024;39:248. 10.1007/s12291-022-01110-3
- Borborema MEA, Miranda DEO, de Lucena TMC, de Lorena VMB, Rabello MCDS, et al. Steroid immune responsive gene regulation in Mycobacterium tuberculosis infection in vitro. Tuberculosis (Edinb). 2024;146:102497. 10.1016/j.tube.2024.102497
